Development Level

Tbio 15 | 11,445
Tchem 9 | 1,598
Tclin 1 | 613

IMPC Phenotype

decreased vertical activity 2 | 208
enlarged heart 2 | 210
increased circulating choleste... 2 | 66
preweaning lethality, incomple... 2 | 499
abnormal cecum morphology 1 | 7
abnormal heart morphology 1 | 162
abnormal heart shape 1 | 5
abnormal seminal vesicle morph... 1 | 114
absent pinna reflex 1 | 23
cardiovascular system phenotyp... 1 | 36
decreased cardiac muscle contr... 1 | 11
decreased circulating HDL chol... 1 | 68
decreased circulating choleste... 1 | 93
decreased circulating unsatura... 1 | 2
decreased heart rate 1 | 18
decreased total body fat amoun... 1 | 207
enlarged cecum 1 | 5
enlarged seminal vesicle 1 | 10
enlarged spleen 1 | 41
hydrometra 1 | 53
hypoactivity 1 | 132
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating chloride... 1 | 41
increased circulating free fat... 1 | 20
increased circulating iron lev... 1 | 30
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
preweaning lethality, complete... 1 | 979
prolonged PQ interval 1 | 5
prolonged QT interval 1 | 38
small adrenal glands 1 | 16
small superior vagus ganglion 1 | 74

Disease

ovarian cancer 18 | 8,520
Carcinoma 16 | 11,493
psoriasis 14 | 6,694
osteosarcoma 12 | 7,950
Obesity 9 | 678
lung cancer 9 | 4,740
Atherosclerosis 8 | 291
Breast cancer 8 | 3,578
Coronary artery disease 8 | 268
diabetes mellitus 8 | 1,728
ependymoma 8 | 4,679
glioblastoma 8 | 5,792
invasive ductal carcinoma 8 | 2,951
Astrocytoma, Pilocytic 7 | 3,081
Autosomal recessive predisposition 7 | 1,442
ductal carcinoma in situ 7 | 1,745
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
pancreatic cancer 7 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
subependymal giant cell astrocytoma 7 | 2,287
Hypertensive disease 6 | 292
Kidney cancer 6 | 2,613
Lipid metabolism disorder 6 | 114
adrenocortical carcinoma 6 | 1,428
atypical teratoid / rhabdoid tumor 6 | 5,112
lung carcinoma 6 | 2,843
medulloblastoma, large-cell 6 | 6,241
Fatty liver disease 5 | 103
Heart disease 5 | 306
Hypercholesterolemia 5 | 44
Liver Cirrhosis, Experimental 5 | 769
active Crohn's disease 5 | 922
breast carcinoma 5 | 1,638
cystic fibrosis 5 | 1,696
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
tuberculosis 5 | 2,010
Cardiovascular system disease 4 | 246
Familial hypercholesterolemia - homozygous 4 | 7
Hepatomegaly 4 | 285
Hypercholesterolemia, Familial 4 | 23
Hyperlipoproteinemia Type IIa 4 | 11
Hypertension 4 | 396
Myocardial Ischemia 4 | 169
Rheumatoid arthritis 4 | 1,191
Serum cholesterol raised 4 | 22
acute quadriplegic myopathy 4 | 1,158
adult high grade glioma 4 | 3,801
aldosterone-producing adenoma 4 | 665
lung adenocarcinoma 4 | 2,716
oligodendroglioma 4 | 2,850
pituitary cancer 4 | 1,972
primitive neuroectodermal tumor 4 | 3,035
ulcerative colitis 4 | 1,819
Angina Pectoris 3 | 32
Arcus Senilis 3 | 11
Atherosclerosis of aorta 3 | 5
Atopic dermatitis 3 | 952
Cancer 3 | 2,499
Cataract 8 multiple types 3 | 33
Cerebrovascular disease 3 | 238
Chemical and Drug Induced Liver Injury 3 | 195
Coronary Arteriosclerosis 3 | 6
Coronary Disease 3 | 25
Coronary artery disease, premature 3 | 6
Coronary heart disease 3 | 16
Down syndrome 3 | 499
Duchenne muscular dystrophy 3 | 601
Dyspnea 3 | 76
Heart murmur 3 | 5
Hyperglycemia 3 | 137
Hyperinsulinism 3 | 133
Hyperlipidemia 3 | 43
Impaired left ventricular function 3 | 16
Insulin Resistance 3 | 72
Internal carotid artery abnormalities 3 | 3
Kidney Failure, Chronic 3 | 46
Kidney disease 3 | 430
Left-Sided Heart Failure 3 | 16
Liver disease 3 | 237
Low density lipoprotein increased 3 | 8
Mental and motor retardation 3 | 608
Multiple myeloma 3 | 1,332
Myocardial Infarction 3 | 151
Neonatal Jaundice 3 | 30
Non-alcoholic Fatty Liver Disease 3 | 42
Plaque build-up in arteries supplying blood to heart 3 | 6
Polycystic ovary syndrome 3 | 360
Precocious atherosclerosis 3 | 4
Premature arteriosclerosis 3 | 5
Renal Artery Stenosis 3 | 9
Steatohepatitis 3 | 44
Sudden Cardiac Death 3 | 29
Vascular disease 3 | 319
astrocytic glioma 3 | 2,597
fibroadenoma 3 | 559
group 3 medulloblastoma 3 | 4,104
interstitial cystitis 3 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
non-small cell lung cancer 3 | 2,890
pancreatic carcinoma 3 | 562

Tissue

Blood and immune system 25 | 16,909
Digestive Tract 25 | 17,369
Endocrine System 25 | 18,159
Female tissues 25 | 17,400
Liver and Pancreas 25 | 16,750
Male tissues 25 | 17,142
Skin and soft tissues 25 | 17,230
Urinary Tract 25 | 16,678
Respiratory system 24 | 16,393
Cardiovascular System 23 | 15,192
Nervous System 23 | 16,725

Target Family

Non-IDG 17 | 12,091
Enzyme 8 | 4,145

GO Process

low-density lipoprotein partic... 25 | 25
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Scavenger receptor class B member 1 SCARB1 Tchem Non-IDG -2.93920 915.7 378
Diacylglycerol O-acyltransferase 2 DGAT2 Tchem Enzyme -2.07482 112.0 230
Niemann-Pick C1 protein NPC1 Tbio Non-IDG -2.71962 551.3 284
Clathrin heavy chain 1 CLTC Tbio Non-IDG -1.66258 38.8 231
Lysosomal acid lipase/cholesteryl ester hydrolase LIPA Tchem Enzyme -2.80202 616.3 170
Clathrin light chain A CLTA Tbio Non-IDG -1.32676 16.0 244
Sterol O-acyltransferase 2 SOAT2 Tchem Enzyme -1.60747 40.5 68
Apolipoprotein B-100 APOB Tchem Non-IDG -4.00022 10024.1 856
Low-density lipoprotein receptor LDLR Tchem Non-IDG -3.06808 938.9 585
Platelet glycoprotein 4 CD36 Tbio Non-IDG -2.63884 376.0 1155