Development Level

Tbio 45 | 10,625
Tchem 17 | 1,890
Tclin 16 | 602
Tdark 3 | 7,003

Collection

Eligible non-olfactory GPCR Proteins 3 | 143
Eligible Ion Channel Proteins 1 | 117
Eligible Kinase Proteins 1 | 134

IMPC Term

abnormal behavior 4 | 226
decreased bone mineral content 3 | 157
decreased fasted circulating g... 3 | 49
decreased grip strength 3 | 123
hyperactivity 3 | 108
increased blood urea nitrogen ... 3 | 44
abnormal epididymis morphology 2 | 31
decreased circulating amylase ... 2 | 24
decreased lean body mass 2 | 195
impaired righting response 2 | 19
increased circulating creatini... 2 | 29
increased circulating sodium l... 2 | 71
preweaning lethality, complete... 2 | 633
preweaning lethality, incomple... 2 | 260
abnormal behavioral response t... 1 | 52
abnormal bone structure 1 | 131
abnormal coping response 1 | 12
abnormal eyelid aperture 1 | 3
abnormal gait 1 | 51
abnormal lens morphology 1 | 73
abnormal sleep behavior 1 | 63
abnormal social/conspecific in... 1 | 3
abnormal startle reflex 1 | 14
abnormal tooth morphology 1 | 24
absent pinna reflex 1 | 21
absent teeth 1 | 4
anophthalmia 1 | 20
cataract 1 | 26
decreased NK T cell number 1 | 28
decreased NK cell number 1 | 16
decreased basophil cell number 1 | 11
decreased body weight 1 | 174
decreased circulating bilirubi... 1 | 14
decreased circulating insulin ... 1 | 75
decreased circulating triglyce... 1 | 83
decreased eosinophil cell numb... 1 | 41
decreased exploration in new e... 1 | 9
decreased heart weight 1 | 44
decreased red blood cell distr... 1 | 11
decreased respiratory quotient 1 | 12
decreased startle reflex 1 | 48
decreased total body fat amoun... 1 | 186
decreased vertical activity 1 | 22
enlarged epididymis 1 | 27
enlarged heart 1 | 111
hypoactivity 1 | 89
impaired pupillary reflex 1 | 14
improved glucose tolerance 1 | 56
increased body weight 1 | 42
increased circulating alanine ... 1 | 11
increased circulating alkaline... 1 | 119
increased circulating chloride... 1 | 43
increased coping response 1 | 3
increased exploration in new e... 1 | 56
increased grip strength 1 | 83
increased heart rate 1 | 17
increased heart weight 1 | 37
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 93
male infertility 1 | 62
mydriasis 1 | 9
premature death 1 | 5
short snout 1 | 4
shortened ST segment 1 | 9
shortened head 1 | 2
straub tail 1 | 26

Disease

glioblastoma 46 | 5,572
medulloblastoma, large-cell 46 | 6,234
psoriasis 41 | 6,685
osteosarcoma 37 | 7,933
ovarian cancer 36 | 8,484
pilocytic astrocytoma 36 | 3,086
atypical teratoid / rhabdoid tumor 34 | 4,369
oligodendroglioma 32 | 2,849
astrocytic glioma 26 | 2,241
primitive neuroectodermal tumor 25 | 3,031
lung cancer 24 | 4,466
pediatric high grade glioma 24 | 2,712
Carcinoma 21 | 2,147
lung carcinoma 21 | 2,844
pituitary cancer 21 | 1,972
Breast cancer 20 | 3,094
adult high grade glioma 20 | 2,148
subependymal giant cell astrocytoma 19 | 2,287
ependymoma 18 | 2,514
invasive ductal carcinoma 18 | 2,950
malignant mesothelioma 18 | 3,162
Schizophrenia 17 | 501
medulloblastoma 17 | 1,524
Cancer 15 | 2,346
Parkinson's disease 14 | 364
Pick disease 14 | 1,893
group 3 medulloblastoma 14 | 2,254
posterior fossa group A ependymoma 14 | 1,511
Attention deficit hyperactivity disorder 13 | 156
Obesity 13 | 616
intraductal papillary-mucinous neoplasm (IPMN) 13 | 3,289
lung adenocarcinoma 13 | 2,713
cystic fibrosis 12 | 1,665
intraductal papillary-mucinous carcinoma (IPMC) 12 | 2,988
non-small cell lung cancer 12 | 2,798
Alcohol dependence 11 | 107
Epilepsy 11 | 346
Intellectual disability 11 | 573
Neurodegenerative disease 11 | 383
breast carcinoma 11 | 1,614
group 4 medulloblastoma 11 | 1,875
intraductal papillary-mucinous adenoma (IPMA) 11 | 2,956
pancreatic cancer 11 | 2,300
Alzheimer's disease 10 | 644
Atopic dermatitis 10 | 944
Seizures 10 | 95
Toxic encephalopathy 10 | 131
colon cancer 10 | 1,475
ductal carcinoma in situ 10 | 1,745
Autistic Disorder 9 | 320
adrenocortical carcinoma 9 | 1,427
posterior fossa group B ependymoma 9 | 1,530
Cocaine-Related Disorders 8 | 88
Substance Withdrawal Syndrome 8 | 52
astrocytoma 8 | 1,493
sonic hedgehog group medulloblastoma 8 | 1,482
Bipolar Disorder 7 | 266
Cocaine dependence 7 | 24
Dystonia 7 | 77
Nerve Degeneration 7 | 73
Nicotine dependence 7 | 53
aldosterone-producing adenoma 7 | 664
diabetes mellitus 7 | 1,663
interstitial cystitis 7 | 2,299
tuberculosis 7 | 1,557
Amphetamine-Related Disorders 6 | 74
Amyotrophic Lateral Sclerosis 6 | 431
Anxiety Disorders 6 | 37
Brain disease 6 | 83
Down syndrome 6 | 548
Substance abuse 6 | 55
atypical teratoid/rhabdoid tumor 6 | 1,095
juvenile dermatomyositis 6 | 1,189
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,795
Adenoma 5 | 165
Choreatic disease 5 | 27
Huntington's disease 5 | 72
Hyperactive behavior 5 | 31
Hypertensive disease 5 | 193
Major Depressive Disorder 5 | 106
Pain 5 | 70
acute quadriplegic myopathy 5 | 1,157
cutaneous lupus erythematosus 5 | 1,056
nasopharyngeal carcinoma 5 | 1,056
nervous system disorder 5 | 53
Acquired metabolic disease 4 | 267
Asthma 4 | 349
Fragile X syndrome 4 | 31
Movement Disorders 4 | 21
Multiple myeloma 4 | 1,327
Nonsyndromic deafness 4 | 121
Pain agnosia 4 | 99
Rheumatoid Arthritis 4 | 1,160
Vascular disease 4 | 281
Waldenstrons macroglobulinemia 4 | 765
active Crohn's disease 4 | 918
dermatomyositis 4 | 933
primary pancreatic ductal adenocarcinoma 4 | 1,271
spina bifida 4 | 1,064
ulcerative colitis 4 | 2,087

Tissue

Digestive Tract 81 | 18,473
Endocrine System 81 | 18,512
Female tissues 81 | 18,647
Nervous System 81 | 18,561
Skin and soft tissues 81 | 18,115
Urinary Tract 81 | 18,444
Cardiovascular System 80 | 17,958
Liver and Pancreas 79 | 18,136
Respiratory system 78 | 17,484
Blood and immune system 77 | 17,995
Male tissues 77 | 17,969

Target Family

Non-IDG 31 | 11,971
Enzyme 18 | 4,146
GPCR 13 | 406
Transcription Factor 9 | 1,400
Ion Channel 6 | 341
Transporter 3 | 473
Kinase 1 | 634

GO Process

locomotory behavior 81 | 81
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
D(2) dopamine receptor DRD2 Tclin GPCR -3.24474 1775.2 248
Methyl-CpG-binding protein 2 MECP2 Tchem Transcription Factor -3.22710 1827.6 567
Voltage-dependent N-type calcium channel subunit alpha-1B CACNA1B Tclin Ion Channel -2.21210 162.9 67
Striatin STRN Tbio Non-IDG -1.63637 51.0 118
Selenoprotein P SELENOP Tbio Non-IDG -2.42408 315.2 94
Mu-type opioid receptor OPRM1 Tclin GPCR -3.20440 1609.2 372
Neuropeptide Y receptor type 1 NPY1R Tchem GPCR -2.39345 177.9 280
Ubiquitin-like modifier-activating enzyme 6 UBA6 Tchem Non-IDG -0.80386 7.32 154
Neuron navigator 2 NAV2 Tbio Non-IDG -1.53469 35.6 51
Plasma membrane calcium-transporting ATPase 2 ATP2B2 Tbio Transporter -2.03165 116.3 74