Development Level

Tbio 6 | 11,445

Collection

GPCR: IDG Consortium (Complete... 1 | 25

IMPC Phenotype

decreased vertical activity 2 | 208
abnormal behavior 1 | 298
abnormal coat-hair pigmentatio... 1 | 64
abnormal eye morphology 1 | 68
abnormal eye size 1 | 7
abnormal heart morphology 1 | 162
abnormal retina morphology 1 | 71
decreased hemoglobin content 1 | 68
enlarged heart 1 | 210
hydrops fetalis 1 | 1
hyperactivity 1 | 148
microphthalmia 1 | 26

Disease

Carcinoma 5 | 11,493
medulloblastoma, large-cell 5 | 6,241
atypical teratoid / rhabdoid tumor 4 | 5,112
invasive ductal carcinoma 4 | 2,951
Astrocytoma, Pilocytic 3 | 3,081
Epilepsy 3 | 792
Kidney cancer 3 | 2,613
ductal carcinoma in situ 3 | 1,745
ependymoma 3 | 4,679
glioblastoma 3 | 5,792
lung adenocarcinoma 3 | 2,716
lung cancer 3 | 4,740
non-small cell lung cancer 3 | 2,890
oligodendroglioma 3 | 2,850
osteosarcoma 3 | 7,950
ovarian cancer 3 | 8,520
primitive neuroectodermal tumor 3 | 3,035
psoriasis 3 | 6,694
subependymal giant cell astrocytoma 3 | 2,287
Autosomal recessive predisposition 2 | 1,442
Breast cancer 2 | 3,578
Cerebellar Ataxia 2 | 304
Infantile onset 2 | 238
Retinal Diseases 2 | 55
Seizures 2 | 596
adult high grade glioma 2 | 3,801
astrocytic glioma 2 | 2,597
interstitial cystitis 2 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
malignant mesothelioma 2 | 3,232
medulloblastoma 2 | 720
pituitary cancer 2 | 1,972
'Curvilinear profiles' ultrastructurally in cells 1 | 5
'Fingerprint profiles' ultrastructurally in cells 1 | 3
'Rectilinear' profiles ultrastructurally 1 | 2
Abnormal nervous system electrophysiology 1 | 3
Adult Neuronal Ceroid Lipofuscinosis 1 | 1
Adult onset 1 | 82
Arachnodactyly 1 | 49
Atrophic 1 | 10
Atrophy 1 | 10
Attention Deficit Disorder with Hyperactivity 1 | 21
Blind Vision 1 | 111
Blindness 1 | 88
Blindness, Legal 1 | 110
CEROID LIPOFUSCINOSIS, NEURONAL, 6 1 | 6
Ceroid Lipofuscinosis, Neuronal, 4A, Autosomal Recessive 1 | 1
Ceroid lipofuscinosis neuronal 6 1 | 2
Chediak-Higashi syndrome 1 | 26
Craniofacial Abnormalities 1 | 151
Decreased visual acuity, progressive 1 | 36
Degenerative brain disorder 1 | 100
Diplopia 1 | 8
Disease Models, Animal 1 | 155
Extrapyramidal Disorders 1 | 29
Extrapyramidal sign 1 | 29
Frequent fractures 1 | 53
GRISCELLI SYNDROME, TYPE 3 1 | 2
Granular osmiophilic deposits (GROD) in cells 1 | 1
Griscelli syndrome 1 | 24
Hallucinations, Auditory 1 | 2
Hallucinations, Visual 1 | 6
Hermansky-Pudlak syndrome 1 | 42
Hyperlipidemia 1 | 43
Hypopigmentation disorder 1 | 25
Increased fracture rate 1 | 53
Increased neuronal autofluorescent lipopigment 1 | 7
Inflammation 1 | 120
Leukoencephalopathies 1 | 29
Lymphoid leukemia 1 | 160
Mesothelioma, Malignant 1 | 105
Motor Skills Disorders 1 | 8
Motor deterioration 1 | 5
Muscle Hypertonia 1 | 88
Myoclonic Epilepsies, Progressive 1 | 44
Myoclonus 1 | 74
Neuronal Ceroid-Lipofuscinoses 1 | 4
Neuronal ceroid lipofuscinosis 1 | 28
Neuronal ceroid lipofuscinosis 6 1 | 1
Neuronal lipopigments 1 | 7
Norrie disease 1 | 14
Peripheral Neuropathy 1 | 134
Pigmentary iris degeneration 1 | 20
Pigmentary retinal degeneration 1 | 11
Progressive visual loss 1 | 36
Reduced visual acuity 1 | 63
Retinal Degeneration 1 | 106
Retinal Detachment 1 | 51
Retinal Neovascularization 1 | 4
Retinal exudates 1 | 11
Retinopathy of prematurity 1 | 22
Slow progression 1 | 89
Supratentorial atrophy 1 | 94
Varying degree of multiple fractures 1 | 53
Vision Disorders 1 | 6
Visual pathway disease 1 | 4
Weight Loss 1 | 24
Weight decreased 1 | 103
chronic kidney disease 1 | 90
non-small cell lung carcinoma 1 | 317

Tissue

Blood and immune system 6 | 16,909
Cardiovascular System 6 | 15,192
Digestive Tract 6 | 17,369
Endocrine System 6 | 18,159
Female tissues 6 | 17,400
Liver and Pancreas 6 | 16,750
Male tissues 6 | 17,142
Nervous System 6 | 16,725
Respiratory system 6 | 16,393
Skin and soft tissues 6 | 17,230
Urinary Tract 6 | 16,678

Target Family

GPCR 3 | 408
Non-IDG 2 | 12,091
Enzyme 1 | 4,145

GO Process

locomotion involved in locomot... 6 | 6
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ceroid-lipofuscinosis neuronal protein 6 CLN6 Tbio Non-IDG -1.87357 0.00000 103
Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform PPP3CB Tbio Enzyme -1.53531 28.2 147
Adhesion G protein-coupled receptor L3 ADGRL3 Tbio GPCR -2.72560 511.0 123
Unconventional myosin-Va MYO5A Tbio Non-IDG -1.77097 54.9 83
Frizzled-4 FZD4 Tbio GPCR -2.05508 106.8 313
Prosaposin receptor GPR37 GPR37 Tbio GPCR -1.52739 42.5 191