Development Level

Tbio 95 | 11,651
Tdark 57 | 6,593
Tchem 34 | 1,388
Tclin 20 | 612

Collection

GPCR: IDG Consortium (Targets) 2 | 126
RFA-RM-18-021 2 | 328

IMPC Phenotype

preweaning lethality, incomple... 9 | 499
preweaning lethality, complete... 6 | 979
decreased total body fat amoun... 4 | 207
decreased circulating creatini... 3 | 39
decreased circulating glucose ... 3 | 126
decreased lymphocyte cell numb... 3 | 83
increased neutrophil cell numb... 3 | 46
abnormal femur morphology 2 | 14
abnormal gait 2 | 69
abnormal retina morphology 2 | 71
decreased circulating insulin ... 2 | 76
decreased leukocyte cell numbe... 2 | 73
decreased mean corpuscular vol... 2 | 79
decreased startle reflex 2 | 75
embryonic lethality prior to t... 2 | 278
increased circulating glucose ... 2 | 24
increased erythrocyte cell num... 2 | 39
increased lean body mass 2 | 172
increased mean corpuscular hem... 2 | 36
increased monocyte cell number 2 | 63
increased spleen weight 2 | 10
short tibia 2 | 97
abnormal behavior 1 | 298
abnormal coat-hair pigmentatio... 1 | 64
abnormal colon morphology 1 | 3
abnormal cornea morphology 1 | 31
abnormal eye anterior chamber ... 1 | 9
abnormal eye morphology 1 | 68
abnormal ileum morphology 1 | 2
abnormal kidney morphology 1 | 65
abnormal maxilla morphology 1 | 17
abnormal optic disc morphology 1 | 10
abnormal pericardium morpholog... 1 | 26
abnormal seminal vesicle morph... 1 | 114
abnormal sleep behavior 1 | 70
abnormal vitreous body morphol... 1 | 10
cataract 1 | 92
convulsive seizures 1 | 13
decreased blood urea nitrogen ... 1 | 51
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased circulating aspartat... 1 | 34
decreased circulating magnesiu... 1 | 13
decreased circulating serum al... 1 | 82
decreased circulating triglyce... 1 | 79
decreased coping response 1 | 8
decreased fasted circulating g... 1 | 65
decreased glycosylated hemoglo... 1 | 1
decreased grip strength 1 | 116
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased large unstained cell... 1 | 11
decreased lean body mass 1 | 135
decreased mean corpuscular hem... 1 | 50
decreased red blood cell distr... 1 | 41
decreased vertical activity 1 | 208
dilated heart left ventricle 1 | 11
edema 1 | 59
embryonic lethality prior to o... 1 | 239
enlarged heart 1 | 210
enlarged spleen 1 | 41
impaired glucose tolerance 1 | 75
increased blood urea nitrogen ... 1 | 48
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased circulating glycerol... 1 | 9
increased circulating sodium l... 1 | 71
increased circulating thyroxin... 1 | 7
increased circulating triglyce... 1 | 42
increased eosinophil cell numb... 1 | 11
increased heart weight 1 | 62
increased hemoglobin content 1 | 45
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 96
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
male infertility 1 | 123
mydriasis 1 | 6
pale yolk sac 1 | 25
polycystic kidney 1 | 15
prenatal lethality 1 | 28
thrombocytopenia 1 | 56
tremors 1 | 39

Disease

osteosarcoma 104 | 7,950
Carcinoma 99 | 11,493
Cancer 87 | 2,499
lung cancer 81 | 4,740
psoriasis 80 | 6,694
glioblastoma 79 | 5,792
ovarian cancer 79 | 8,520
interstitial cystitis 65 | 2,312
invasive ductal carcinoma 64 | 2,951
non-small cell lung cancer 64 | 2,890
Breast cancer 61 | 3,578
medulloblastoma, large-cell 61 | 6,241
lung adenocarcinoma 57 | 2,716
lung carcinoma 56 | 2,843
malignant mesothelioma 52 | 3,232
ulcerative colitis 51 | 1,819
atypical teratoid / rhabdoid tumor 49 | 5,112
intraductal papillary-mucinous neoplasm (IPMN) 48 | 3,291
Astrocytoma, Pilocytic 47 | 3,081
intraductal papillary-mucinous carcinoma (IPMC) 47 | 2,989
pancreatic cancer 46 | 2,398
tuberculosis 45 | 2,010
ependymoma 42 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 42 | 2,955
adult high grade glioma 41 | 3,801
cutaneous lupus erythematosus 40 | 1,057
diabetes mellitus 36 | 1,728
group 3 medulloblastoma 34 | 4,104
cystic fibrosis 33 | 1,696
ductal carcinoma in situ 33 | 1,745
colon cancer 32 | 1,478
subependymal giant cell astrocytoma 32 | 2,287
Autosomal recessive predisposition 29 | 1,442
breast carcinoma 29 | 1,638
oligodendroglioma 27 | 2,850
Kidney cancer 26 | 2,613
Schizophrenia 26 | 1,160
astrocytoma 26 | 1,146
juvenile dermatomyositis 24 | 1,187
primary pancreatic ductal adenocarcinoma 24 | 1,109
dermatomyositis 23 | 966
mucosa-associated lymphoid tissue lymphoma 23 | 484
periodontitis 23 | 293
pituitary cancer 23 | 1,972
primary Sjogren syndrome 23 | 735
primitive neuroectodermal tumor 22 | 3,035
Liver Cirrhosis, Experimental 21 | 769
pancreatic ductal adenocarcinoma liver metastasis 21 | 1,962
Arthritis 20 | 290
adrenocortical carcinoma 20 | 1,428
Hypertension 19 | 396
astrocytic glioma 19 | 2,597
Coronary artery disease 18 | 268
Hypersensitivity reaction type II disease 18 | 253
gastric carcinoma 18 | 807
pediatric high grade glioma 18 | 1,064
Duchenne muscular dystrophy 17 | 601
Kidney disease 17 | 430
Multiple myeloma 17 | 1,332
Rheumatoid arthritis 17 | 1,191
Vascular disease 17 | 319
esophageal adenocarcinoma 17 | 737
nasopharyngeal carcinoma 17 | 1,058
Atherosclerosis 16 | 291
Down syndrome 16 | 499
active ulcerative colitis 16 | 764
group 4 medulloblastoma 16 | 1,855
pancreatic carcinoma 16 | 562
Anemia 14 | 365
Asthma 13 | 385
Atopic dermatitis 13 | 952
Cerebrovascular disease 13 | 238
Heart disease 13 | 306
Multiple Sclerosis 13 | 540
Waldenstrons macroglobulinemia 13 | 765
active Crohn's disease 13 | 922
acute myeloid leukemia 13 | 783
head and neck cancer and chronic obstructive pulmonary disease 13 | 239
non-small cell lung carcinoma 13 | 317
Breast Neoplasms 12 | 445
Muscle hypotonia 12 | 571
chronic lymphosyte leukemia 12 | 204
nephrosclerosis 12 | 333
Hypertensive disease 11 | 292
Liver disease 11 | 237
Malaria 11 | 160
Mammary Neoplasms 11 | 425
Neoplasm Metastasis 11 | 168
Prostatic Neoplasms 11 | 495
Short stature 11 | 531
Stomach Neoplasms 11 | 300
Thrombocytopenia 11 | 197
acute quadriplegic myopathy 11 | 1,158
autosomal dominant Emery-Dreifuss muscular dystrophy 11 | 510
Epilepsy 10 | 792
Inflammatory bowel disease 10 | 151
Lung Neoplasms 10 | 232
Lung disease 10 | 142
Pick disease 10 | 1,894
Seizures 10 | 596

Tissue

Blood and immune system 141 | 16,909
Endocrine System 141 | 18,159
Digestive Tract 140 | 17,369
Skin and soft tissues 140 | 17,230
Female tissues 139 | 17,400
Urinary Tract 139 | 16,678
Male tissues 136 | 17,142
Liver and Pancreas 135 | 16,750
Respiratory system 135 | 16,393
Nervous System 132 | 16,725
Cardiovascular System 124 | 15,192

Target Family

Non-IDG 150 | 12,091
Enzyme 20 | 4,145
Transporter 14 | 473
Kinase 11 | 634
GPCR 9 | 408
Transcription Factor 2 | 1,400

GO Process

leukocyte migration 206 | 206
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Syndecan-4 SDC4 Tbio Non-IDG -2.39649 274.8 297
Integrin alpha-3 ITGA3 Tbio Non-IDG -2.08360 104.1 587
Monocarboxylate transporter 3 SLC16A8 Tbio Transporter -1.52718 33.5 105
Pre-B lymphocyte protein 3 VPREB3 Tbio Non-IDG -0.73715 7.27 71
E-selectin SELE Tchem Non-IDG -3.44926 2672.1 919
Platelet glycoprotein VI GP6 Tbio Non-IDG -2.73714 584.5 201
Transforming growth factor beta-1 TGFB1 Tchem Non-IDG -3.84680 5672.0 1222
Matrix metalloproteinase-9 MMP9 Tchem Enzyme -3.96102 8811.6 1442
Glycophorin-A GYPA Tbio Non-IDG -3.08954 1166.7 1045
Macrophage migration inhibitory factor MIF Tchem Non-IDG -3.21333 1538.5 527