Development Level

Tbio 27 | 11,651
Tchem 2 | 1,388
Tdark 2 | 6,593
Tclin 1 | 612

IMPC Phenotype

preweaning lethality, incomple... 3 | 499
abnormal embryo size 2 | 220
abnormal eye morphology 2 | 68
abnormal neural tube closure 2 | 46
edema 2 | 59
hydrometra 2 | 53
hypoactivity 2 | 132
small superior vagus ganglion 2 | 74
abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
abnormal craniofacial morpholo... 1 | 33
abnormal forebrain development 1 | 20
abnormal heart morphology 1 | 162
abnormal hindbrain morphology 1 | 10
abnormal kidney morphology 1 | 65
abnormal midbrain morphology 1 | 10
abnormal placenta size 1 | 20
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal sleep behavior 1 | 70
abnormal social-conspecific in... 1 | 3
anophthalmia 1 | 33
cardiovascular system phenotyp... 1 | 36
decreased body weight 1 | 161
decreased circulating amylase ... 1 | 28
decreased circulating triglyce... 1 | 79
decreased eosinophil cell numb... 1 | 24
decreased exploration in new e... 1 | 11
decreased heart rate variabili... 1 | 13
decreased lymphocyte cell numb... 1 | 83
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
enlarged uterus 1 | 11
female infertility 1 | 60
hyperactivity 1 | 148
increased circulating alkaline... 1 | 122
increased coping response 1 | 4
increased exploration in new e... 1 | 8
increased fasted circulating g... 1 | 76
increased heart rate 1 | 23
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
male infertility 1 | 123
microphthalmia 1 | 26
pale yolk sac 1 | 25
pallor 1 | 34
shortened ST segment 1 | 10

Disease

Carcinoma 20 | 11,493
Cataract 14 | 297
ovarian cancer 13 | 8,520
atypical teratoid / rhabdoid tumor 12 | 5,112
medulloblastoma, large-cell 12 | 6,241
ependymoma 11 | 4,679
Breast cancer 10 | 3,578
glioblastoma 10 | 5,792
group 3 medulloblastoma 10 | 4,104
osteosarcoma 10 | 7,950
psoriasis 10 | 6,694
Cancer 9 | 2,499
Kidney cancer 8 | 2,613
Nuclear cataract 8 | 19
Nuclear non-senile cataract 8 | 18
lung cancer 8 | 4,740
pituitary cancer 8 | 1,972
Lens Opacities 7 | 231
cystic fibrosis 7 | 1,696
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
pancreatic cancer 7 | 2,398
primitive neuroectodermal tumor 7 | 3,035
Astrocytoma, Pilocytic 6 | 3,081
CATARACT 16, MULTIPLE TYPES 6 | 15
Microphthalmia 6 | 76
Schizophrenia 6 | 1,160
ductal carcinoma in situ 6 | 1,745
lung carcinoma 6 | 2,843
malignant mesothelioma 6 | 3,232
non-small cell lung cancer 6 | 2,890
Autosomal recessive predisposition 5 | 1,442
Congenital Bilateral Cataracts 5 | 50
Congenital cataract 5 | 50
Dull intelligence 5 | 645
Intellectual disability 5 | 1,016
Low intelligence 5 | 645
Mental Retardation 5 | 645
Mental deficiency 5 | 645
Poor school performance 5 | 645
astrocytoma 5 | 1,146
colon cancer 5 | 1,478
interstitial cystitis 5 | 2,312
invasive ductal carcinoma 5 | 2,951
oligodendroglioma 5 | 2,850
subependymal giant cell astrocytoma 5 | 2,287
Abnormally small eyeball 4 | 97
Atopic dermatitis 4 | 952
Autistic Disorder 4 | 364
Blindness 4 | 88
Cognitive delay 4 | 608
Congenital total cataract 4 | 15
Decreased size of eyeball 4 | 97
Glaucoma 4 | 239
Global developmental delay 4 | 608
Hypoplastic mandible condyle 4 | 275
Hypotrophic malar bone 4 | 129
Malar flattening 4 | 129
Mandibular hypoplasia 4 | 275
Mental and motor retardation 4 | 608
Micrognathism 4 | 275
Microphthalmos 4 | 100
Myopia 4 | 176
Small head 4 | 374
acute quadriplegic myopathy 4 | 1,158
adult high grade glioma 4 | 3,801
breast carcinoma 4 | 1,638
diabetes mellitus 4 | 1,728
fibroadenoma 4 | 559
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
lung adenocarcinoma 4 | 2,716
Acquired scoliosis 3 | 281
Aortic Valve Insufficiency 3 | 40
Aortic aneurysm 3 | 38
Cardiomegaly 3 | 116
Chest Pain 3 | 38
Cleft uvula 3 | 27
Cloudy cornea 3 | 33
Constipation 3 | 181
Corneal diameter decreased 3 | 47
Corneal stromal opacities 3 | 33
Coronary artery disease 3 | 268
Craniofacial Abnormalities 3 | 151
Curvature of spine 3 | 282
Dyschezia 3 | 135
Dyspnea, Paroxysmal 3 | 13
Epilepsy 3 | 792
Frontal bossing 3 | 157
Gaucher disease type 1 3 | 180
Increase in blood pressure 3 | 119
Left-Sided Heart Failure 3 | 16
Lens subluxation 3 | 12
Low Vision 3 | 174
Pick disease 3 | 1,894
Prostatic Neoplasms 3 | 495
Sclerocornea 3 | 29
Strabismus 3 | 270
Visual Impairment 3 | 174
acute myeloid leukemia 3 | 783
astrocytic glioma 3 | 2,597
sonic hedgehog group medulloblastoma 3 | 467

Tissue

Endocrine System 31 | 18,159
Digestive Tract 28 | 17,369
Skin and soft tissues 25 | 17,230
Blood and immune system 24 | 16,909
Female tissues 24 | 17,400
Liver and Pancreas 24 | 16,750
Male tissues 24 | 17,142
Nervous System 23 | 16,725
Respiratory system 23 | 16,393
Urinary Tract 23 | 16,678
Cardiovascular System 20 | 15,192

Target Family

Non-IDG 20 | 12,091
Transcription Factor 7 | 1,400
Kinase 3 | 634
Enzyme 1 | 4,145
Epigenetic 1 | 242

GO Process

lens development in camera-typ... 32 | 32
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Pygopus homolog 2 PYGO2 Tbio Epigenetic -1.26911 24.4 92
Cell adhesion molecule-related/down-regulated by oncogenes CDON Tbio Non-IDG -2.67247 471.8 128
TGF-beta receptor type-2 TGFBR2 Tchem Kinase -2.84120 665.1 548
Protein Wnt-5a WNT5A Tbio Non-IDG -2.77525 650.2 321
Alpha-crystallin B chain CRYAB Tbio Non-IDG -2.29243 192.0 1100
Disks large homolog 1 DLG1 Tbio Non-IDG -2.19822 171.8 185
Cyclin-dependent kinase 4 CDK4 Tclin Kinase -3.24878 1546.3 803
Trans-acting T-cell-specific transcription factor GATA-3 GATA3 Tbio Transcription Factor -3.20678 1568.2 636
TGF-beta receptor type-1 TGFBR1 Tchem Kinase -2.94747 847.9 413
Protein Wnt-2 WNT2 Tbio Non-IDG -2.28986 167.8 174