Development Level

Tbio 1 | 11,445
Tclin 1 | 613

IMPC Phenotype

embryonic lethality prior to t... 1 | 278
increased startle reflex 1 | 112
preweaning lethality, complete... 1 | 979

Disease

Breast cancer 2 | 3,578
Carcinoma 2 | 11,493
Epilepsy 2 | 792
Kidney cancer 2 | 2,613
Myopathy 2 | 185
Seizures 2 | 596
ependymoma 2 | 4,679
medulloblastoma, large-cell 2 | 6,241
oligodendroglioma 2 | 2,850
ovarian cancer 2 | 8,520
pancreatic cancer 2 | 2,398
subependymal giant cell astrocytoma 2 | 2,287
Adenocarcinoma Of Esophagus 1 | 14
Aortic valve stenosis 1 | 28
Autism Spectrum Disorders 1 | 75
Bannayan-Riley-Ruvalcaba syndrome 1 | 8
Biliary tract cancer 1 | 19
Brachydactyly 1 | 156
Broad ribs 1 | 12
Bushy eyebrows 1 | 49
Carcinoma of pancreas 1 | 5
Carcinoma, Ductal, Breast 1 | 11
Cardiomyopathy, right ventricular 1 | 7
Catecholaminergic polymorphic ventricular tachycardia 1 | 12
Cone-shaped epiphyses 1 | 24
Congenital Camptodactyly 1 | 40
Convex nasal bridge 1 | 57
Decreased projection of maxilla 1 | 66
Decreased projection of midface 1 | 105
Deficiency of upper jaw bones 1 | 66
Diabetic Cardiomyopathies 1 | 10
Diffusely thickened skin 1 | 20
Enlarged vertebral pedicles 1 | 1
Enophthalmos 1 | 75
Familial adenomatous polyposis 1 | 32
Fine hair 1 | 42
Fused vertebrae 1 | 25
Gastrointestinal hamartomatous polyps 1 | 10
Generalized muscle hypertrophy 1 | 1
Growth mental deficiency syndrome of Myhre 1 | 1
Hamartomatous polyp 1 | 10
Hemangioma, Cavernous 1 | 20
Hematochezia 1 | 9
Hereditary hemorrhagic telangiectasia 1 | 13
Hyperopia 1 | 70
Hypertension, Portal 1 | 22
Hypertensive disorder 1 | 56
Hypokalemia 1 | 52
Hypoplasia of the maxilla 1 | 66
Hypoplastic finger 1 | 17
Hypoplastic iliac wing 1 | 19
Hypoplastic toes 1 | 29
Hypotrophic malar bone 1 | 129
Hypotrophic maxilla 1 | 66
Hypotrophic midface 1 | 105
Increased risk of pancreatic cancer 1 | 9
Intermittent migraine headaches 1 | 68
Invasive Ductal Breast Carcinoma 1 | 9
Iron-Refractory Iron Deficiency Anemia 1 | 15
JUVENILE POLYPOSIS/HEREDITARY HEMORRHAGIC TELANGIECTASIA SYNDROME (disorder) 1 | 1
Juvenile polyposis syndrome 1 | 7
Laryngotracheal stenosis 1 | 2
Liver Diseases, Parasitic 1 | 9
Lymphoid leukemia 1 | 160
Malignant hyperthermia 1 | 26
Malignant neoplasm of pancreas 1 | 9
Maxillary retrognathia 1 | 66
Midface retrusion 1 | 105
Migraine Disorders 1 | 76
Overriding toe 1 | 10
Pachyderma 1 | 20
Pancreatic carcinoma, familial 1 | 8
Paroxysmal familial ventricular fibrillation 1 1 | 4
Pericardial effusion 1 | 14
Peutz-Jeghers syndrome 1 | 21
Platyspondyly 1 | 56
Polyposis, Gastric 1 | 4
Prominent nasal bridge 1 | 57
Renal fibrosis 1 | 6
Retrusion of upper jaw bones 1 | 66
Short finger 1 | 17
Short tubular bones 1 | 22
Simple syndactyly of toes, first web space 1 | 23
Small midface 1 | 105
Spinal fusion 1 | 25
Spontaneous haematoma 1 | 8
Stiff skin 1 | 3
Stomach cancer 1 | 30
Sunken eyes 1 | 63
Syncope 1 | 22
Tachycardia, Ventricular 1 | 22
Telangiectasia of the skin 1 | 39
Telangiectasis 1 | 36
Thickened calvaria 1 | 17
Thin upper lip vermilion 1 | 67
Thyroid cancer 1 | 36
Ventricular aneurysm 1 | 2
Vertebral body fusion 1 | 25
Visceral angiomatosis 1 | 13
non-small cell lung carcinoma 1 | 317

Tissue

Blood and immune system 2 | 16,909
Cardiovascular System 2 | 15,192
Digestive Tract 2 | 17,369
Endocrine System 2 | 18,159
Female tissues 2 | 17,400
Liver and Pancreas 2 | 16,750
Male tissues 2 | 17,142
Nervous System 2 | 16,725
Respiratory system 2 | 16,393
Skin and soft tissues 2 | 17,230
Urinary Tract 2 | 16,678

Target Family

Ion Channel 1 | 344
Transcription Factor 1 | 1,400

GO Process

left ventricular cardiac muscl... 2 | 2
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ryanodine receptor 2 RYR2 Tclin Ion Channel -2.92980 851.9 138
Mothers against decapentaplegic homolog 4 SMAD4 Tbio Transcription Factor -3.16129 1349.8 605