Development Level

Tbio 21 | 11,445
Tchem 17 | 1,598
Tclin 8 | 613
Tdark 2 | 6,588

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

abnormal behavior 4 | 298
preweaning lethality, complete... 3 | 979
preweaning lethality, incomple... 3 | 499
abnormal behavioral response t... 2 | 66
decreased circulating alkaline... 2 | 46
decreased circulating total pr... 2 | 49
decreased grip strength 2 | 116
decreased leukocyte cell numbe... 2 | 73
hyperactivity 2 | 148
abnormal limb morphology 1 | 13
abnormal sleep behavior 1 | 70
abnormal tail morphology 1 | 25
cyanosis 1 | 7
decreased basophil cell number 1 | 16
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating bilirubi... 1 | 19
decreased circulating fructosa... 1 | 30
decreased circulating phosphat... 1 | 27
decreased circulating serum al... 1 | 82
decreased food intake 1 | 13
decreased heart left ventricle... 1 | 28
decreased lactate dehydrogenas... 1 | 16
decreased mean corpuscular hem... 1 | 50
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
decreased respiratory quotient 1 | 16
decreased startle reflex 1 | 75
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
edema 1 | 59
hemorrhage 1 | 23
hypoactivity 1 | 132
improved glucose tolerance 1 | 79
increased anxiety-related resp... 1 | 2
increased blood urea nitrogen ... 1 | 48
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating magnesiu... 1 | 10
increased circulating potassiu... 1 | 29
increased startle reflex 1 | 112
polycystic kidney 1 | 15
premature death 1 | 5
respiratory system phenotype 1 | 2
thin ventricular wall 1 | 24
thrombocytopenia 1 | 56

Disease

Carcinoma 39 | 11,493
medulloblastoma, large-cell 28 | 6,241
glioblastoma 26 | 5,792
osteosarcoma 26 | 7,950
psoriasis 25 | 6,694
atypical teratoid / rhabdoid tumor 23 | 5,112
ovarian cancer 22 | 8,520
adult high grade glioma 21 | 3,801
group 3 medulloblastoma 21 | 4,104
ependymoma 17 | 4,679
lung cancer 17 | 4,740
Alzheimer's disease 16 | 658
Breast cancer 16 | 3,578
oligodendroglioma 16 | 2,850
Schizophrenia 15 | 1,160
astrocytic glioma 15 | 2,597
Astrocytoma, Pilocytic 14 | 3,081
Bipolar Disorder 14 | 666
Cancer 14 | 2,499
Intellectual disability 14 | 1,016
Epilepsy 13 | 792
Kidney cancer 13 | 2,613
Depressive disorder 12 | 409
Pick disease 12 | 1,894
primitive neuroectodermal tumor 12 | 3,035
Parkinson's disease 11 | 392
Toxic encephalopathy 11 | 141
invasive ductal carcinoma 11 | 2,951
malignant mesothelioma 11 | 3,232
non-small cell lung cancer 11 | 2,890
subependymal giant cell astrocytoma 11 | 2,287
Seizures 10 | 596
lung adenocarcinoma 10 | 2,716
lung carcinoma 10 | 2,843
Alcoholic Intoxication, Chronic 9 | 289
Autistic Disorder 9 | 364
Dementia 9 | 175
Dull intelligence 9 | 645
Low intelligence 9 | 645
Mental Depression 9 | 333
Mental Retardation 9 | 645
Mental deficiency 9 | 645
Poor school performance 9 | 645
Autosomal recessive predisposition 8 | 1,442
Cognitive delay 8 | 608
Down syndrome 8 | 499
Global developmental delay 8 | 608
Major Depressive Disorder 8 | 301
Mental and motor retardation 8 | 608
pituitary cancer 8 | 1,972
Alzheimer Disease 7 | 83
Cerebrovascular disease 7 | 238
Melanoma 7 | 711
Muscle hypotonia 7 | 571
Unipolar Depression 7 | 250
cutaneous lupus erythematosus 7 | 1,057
cystic fibrosis 7 | 1,696
interstitial cystitis 7 | 2,312
Alcohol dependence 6 | 107
Amyotrophic lateral sclerosis 6 | 451
Brain disease 6 | 96
Disease Models, Animal 6 | 155
Mood Disorders 6 | 184
Neurodegenerative disease 6 | 414
Rheumatoid arthritis 6 | 1,191
Skin cancer 6 | 469
breast carcinoma 6 | 1,638
colon cancer 6 | 1,478
group 4 medulloblastoma 6 | 1,855
pancreatic cancer 6 | 2,398
tuberculosis 6 | 2,010
Alcohol abuse 5 | 50
Attention deficit hyperactivity disorder 5 | 278
Autism spectrum disorder 5 | 101
Brain Ischemia 5 | 110
Cocaine-Related Disorders 5 | 92
Cognition Disorders 5 | 32
Delayed speech and language development 5 | 112
Huntington's disease 5 | 76
Hyperalgesia 5 | 83
Language Delay 5 | 112
Large intestine cancer 5 | 126
Obesity 5 | 678
Speech Delay 5 | 112
Speech impairment 5 | 112
diabetes mellitus 5 | 1,728
ductal carcinoma in situ 5 | 1,745
juvenile dermatomyositis 5 | 1,187
progressive supranuclear palsy 5 | 676
ulcerative colitis 5 | 1,819
Endometriosis 4 | 540
Hypertension 4 | 396
Multiple Sclerosis 4 | 540
Multiple myeloma 4 | 1,332
Status Epilepticus 4 | 98
Vascular disease 4 | 319
dermatomyositis 4 | 966
esophageal adenocarcinoma 4 | 737
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962

Tissue

Endocrine System 48 | 18,159
Digestive Tract 45 | 17,369
Skin and soft tissues 45 | 17,230
Female tissues 44 | 17,400
Liver and Pancreas 44 | 16,750
Nervous System 44 | 16,725
Blood and immune system 43 | 16,909
Respiratory system 42 | 16,393
Male tissues 41 | 17,142
Urinary Tract 41 | 16,678
Cardiovascular System 37 | 15,192

Target Family

Non-IDG 15 | 12,091
Enzyme 10 | 4,145
GPCR 7 | 408
Kinase 6 | 634
Ion Channel 4 | 344
Transcription Factor 4 | 1,400
Nuclear Receptor 1 | 48
Transporter 1 | 473

GO Process

learning or memory 48 | 48
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Adenylate cyclase type 8 ADCY8 Tbio Enzyme -2.04645 112.4 147
E3 ubiquitin-protein ligase AMFR AMFR Tbio Enzyme -2.46909 292.8 203
High affinity nerve growth factor receptor NTRK1 Tclin Kinase -3.05841 1050.9 1092
LIM/homeobox protein Lhx8 LHX8 Tbio Transcription Factor -1.58436 40.6 163
Zinc finger protein 385A ZNF385A Tbio Non-IDG -0.03141 1.24 99
AF4/FMR2 family member 2 AFF2 Tbio Transcription Factor -2.47154 295.5 108
Glycine amidinotransferase, mitochondrial GATM Tbio Enzyme -2.34742 219.1 219
Metabotropic glutamate receptor 5 GRM5 Tchem GPCR -3.12353 1370.3 396
Neuronal acetylcholine receptor subunit alpha-7 CHRFAM7A Tchem Ion Channel -1.81173 87.7 226
Natural resistance-associated macrophage protein 2 SLC11A2 Tchem Transporter -2.53965 373.5 250