Development Level

Tbio 27 | 11,651
Tclin 2 | 612

IMPC Phenotype

preweaning lethality, complete... 3 | 979
abnormal behavior 2 | 298
abnormal bone mineralization 2 | 38
decreased T cell number 2 | 15
decreased body weight 2 | 161
decreased circulating choleste... 2 | 93
increased body weight 2 | 25
increased bone mineral density 2 | 72
increased lean body mass 2 | 172
abnormal bone structure 1 | 187
abnormal eye morphology 1 | 68
abnormal heart morphology 1 | 162
abnormal response to tactile s... 1 | 17
abnormal skin morphology 1 | 50
abnormal stomach morphology 1 | 10
abnormal vibrissa morphology 1 | 25
anophthalmia 1 | 33
decreased IgE level 1 | 6
decreased IgG1 level 1 | 8
decreased NK cell number 1 | 2
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating fructosa... 1 | 30
decreased circulating glucose ... 1 | 126
decreased circulating iron lev... 1 | 32
decreased circulating potassiu... 1 | 20
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased grip strength 1 | 116
decreased heart left ventricle... 1 | 28
decreased hemoglobin content 1 | 68
decreased mature B cell number 1 | 7
decreased thermal nociceptive ... 1 | 2
decreased total body fat amoun... 1 | 207
enlarged heart 1 | 210
enlarged lymph nodes 1 | 37
eye hemorrhage 1 | 1
increased circulating alkaline... 1 | 122
increased circulating calcium ... 1 | 34
increased circulating free fat... 1 | 20
increased circulating total pr... 1 | 28
increased mature B cell number 1 | 1
thin ventricular wall 1 | 24

Disease

Carcinoma 24 | 11,493
ovarian cancer 21 | 8,520
glioblastoma 17 | 5,792
osteosarcoma 17 | 7,950
psoriasis 13 | 6,694
atypical teratoid / rhabdoid tumor 11 | 5,112
medulloblastoma, large-cell 11 | 6,241
lung cancer 10 | 4,740
Astrocytoma, Pilocytic 9 | 3,081
breast carcinoma 9 | 1,638
ependymoma 9 | 4,679
invasive ductal carcinoma 9 | 2,951
Cancer 8 | 2,499
adult high grade glioma 8 | 3,801
lung adenocarcinoma 8 | 2,716
subependymal giant cell astrocytoma 8 | 2,287
tuberculosis 8 | 2,010
Breast cancer 7 | 3,578
astrocytic glioma 7 | 2,597
ductal carcinoma in situ 7 | 1,745
group 4 medulloblastoma 7 | 1,855
interstitial cystitis 7 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
malignant mesothelioma 7 | 3,232
non-small cell lung cancer 7 | 2,890
Kidney cancer 6 | 2,613
Waldenstrons macroglobulinemia 6 | 765
group 3 medulloblastoma 6 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
lung carcinoma 6 | 2,843
primitive neuroectodermal tumor 6 | 3,035
Bipolar Disorder 5 | 666
Intellectual disability 5 | 1,016
colon cancer 5 | 1,478
cystic fibrosis 5 | 1,696
oligodendroglioma 5 | 2,850
Proteinuria 4 | 144
Wiskott-Aldrich syndrome 4 | 30
astrocytoma 4 | 1,146
pancreatic cancer 4 | 2,398
pituitary cancer 4 | 1,972
spina bifida 4 | 1,074
ulcerative colitis 4 | 1,819
Attention deficit hyperactivity disorder 3 | 278
Chronic Lymphocytic Leukemia 3 | 262
Liver Cirrhosis, Experimental 3 | 769
Melanoma 3 | 711
Multiple Sclerosis 3 | 540
Multiple myeloma 3 | 1,332
Nephrotic Syndrome 3 | 78
Pick disease 3 | 1,894
Skin cancer 3 | 469
active ulcerative colitis 3 | 764
acute quadriplegic myopathy 3 | 1,158
adrenocortical carcinoma 3 | 1,428
cutaneous lupus erythematosus 3 | 1,057
dermatomyositis 3 | 966
esophageal adenocarcinoma 3 | 737
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
pediatric high grade glioma 3 | 1,064
primary Sjogren syndrome 3 | 735
Autistic Disorder 2 | 364
Autosomal recessive predisposition 2 | 1,442
Carcinoma, Hepatocellular 2 | 228
Cardiomyopathy, Dilated 2 | 83
Cardiovascular system disease 2 | 246
Depressive disorder 2 | 409
Dull intelligence 2 | 645
Epilepsy 2 | 792
Hirschsprung Disease 2 | 31
Liver cancer 2 | 604
Liver carcinoma 2 | 240
Low intelligence 2 | 645
Major Depressive Disorder 2 | 301
Megacolon 2 | 29
Mental Depression 2 | 333
Mental Retardation 2 | 645
Mental deficiency 2 | 645
Poor school performance 2 | 645
Prostatic Neoplasms 2 | 495
Rheumatoid arthritis 2 | 1,191
Seizures 2 | 596
Substance-Related Disorders 2 | 115
Type 2 diabetes mellitus 2 | 272
Vascular disease 2 | 319
acute myeloid leukemia 2 | 783
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
diabetes mellitus 2 | 1,728
fibroadenoma 2 | 559
gastric carcinoma 2 | 807
juvenile dermatomyositis 2 | 1,187
medulloblastoma 2 | 720
mucosa-associated lymphoid tissue lymphoma 2 | 484
nasopharyngeal carcinoma 2 | 1,058
non-small cell lung carcinoma 2 | 317
pancreatic carcinoma 2 | 562
post-traumatic stress disorder 2 | 40
progressive supranuclear palsy 2 | 676
tuberculosis and treatment for 6 months 2 | 409

Tissue

Blood and immune system 29 | 16,909
Cardiovascular System 29 | 15,192
Digestive Tract 29 | 17,369
Endocrine System 29 | 18,159
Female tissues 29 | 17,400
Liver and Pancreas 29 | 16,750
Male tissues 29 | 17,142
Nervous System 29 | 16,725
Respiratory system 29 | 16,393
Skin and soft tissues 29 | 17,230
Urinary Tract 29 | 16,678

Target Family

Non-IDG 24 | 12,091
Enzyme 3 | 4,145
GPCR 1 | 408
Kinase 1 | 634

GO Process

lamellipodium assembly 29 | 29
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cytoplasmic FMR1-interacting protein 1 CYFIP1 Tbio Non-IDG -1.46134 28.5 64
Guanine nucleotide exchange factor VAV3 VAV3 Tbio Non-IDG -1.82116 74.0 249
Cytoplasmic protein NCK1 NCK1 Tbio Non-IDG -2.25032 186.5 398
Ras-related C3 botulinum toxin substrate 1 RAC1 Tbio Enzyme -1.94674 87.1 452
Guanine nucleotide exchange factor VAV2 VAV2 Tbio Non-IDG -1.81793 64.6 227
Cytoplasmic protein NCK2 NCK2 Tbio Non-IDG -1.57587 36.4 241
Actin-binding LIM protein 3 ABLIM3 Tbio Non-IDG -0.30103 2.18 118
Arfaptin-2 ARFIP2 Tbio Non-IDG -2.07883 109.5 194
Beta-parvin PARVB Tbio Non-IDG -1.26717 17.4 137
Wiskott-Aldrich syndrome protein family member 3 WASF3 Tbio Non-IDG -2.51036 313.7 142