Development Level

Tbio 27 | 10,625
Tclin 2 | 602

IMPC Phenotype

abnormal behavior 2 | 226
abnormal bone mineralization 2 | 55
decreased T cell number 2 | 31
decreased body weight 2 | 174
decreased bone mineral density 2 | 126
decreased circulating choleste... 2 | 85
increased body weight 2 | 42
increased bone mineral density 2 | 52
increased circulating free fat... 2 | 17
preweaning lethality, complete... 2 | 633
abnormal bone structure 1 | 131
abnormal respiratory quotient 1 | 9
abnormal response to tactile s... 1 | 16
abnormal vibrissa morphology 1 | 17
decreased IgE level 1 | 3
decreased IgG1 level 1 | 4
decreased NK cell number 1 | 16
decreased caudal vertebrae num... 1 | 49
decreased circulating HDL chol... 1 | 77
decreased circulating LDL chol... 1 | 37
decreased circulating alanine ... 1 | 53
decreased circulating aspartat... 1 | 27
decreased circulating fructosa... 1 | 31
decreased circulating glucose ... 1 | 121
decreased circulating iron lev... 1 | 25
decreased circulating potassiu... 1 | 17
decreased circulating serum al... 1 | 79
decreased circulating total pr... 1 | 41
decreased circulating triglyce... 1 | 83
decreased hemoglobin content 1 | 53
decreased leukocyte cell numbe... 1 | 54
decreased mature B cell number 1 | 25
decreased thermal nociceptive ... 1 | 4
decreased total body fat amoun... 1 | 186
enlarged lymph nodes 1 | 27
eye hemorrhage 1 | 1
increased circulating alkaline... 1 | 119
increased circulating calcium ... 1 | 32
increased circulating total pr... 1 | 20
increased heart weight 1 | 37
increased lean body mass 1 | 107
increased mature B cell number 1 | 12

Disease

ovarian cancer 21 | 8,491
glioblastoma 17 | 5,572
osteosarcoma 17 | 7,933
psoriasis 13 | 6,685
medulloblastoma, large-cell 11 | 6,234
pediatric high grade glioma 10 | 2,712
atypical teratoid / rhabdoid tumor 9 | 4,369
breast carcinoma 9 | 1,614
invasive ductal carcinoma 9 | 2,950
lung cancer 9 | 4,473
pilocytic astrocytoma 9 | 3,086
lung adenocarcinoma 8 | 2,714
subependymal giant cell astrocytoma 8 | 2,287
tuberculosis 8 | 1,563
Breast cancer 7 | 3,098
Cancer 7 | 2,346
astrocytoma 7 | 1,493
ductal carcinoma in situ 7 | 1,745
interstitial cystitis 7 | 2,299
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,289
Waldenstrons macroglobulinemia 6 | 764
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,988
lung carcinoma 6 | 2,844
malignant mesothelioma 6 | 3,163
non-small cell lung cancer 6 | 2,798
primitive neuroectodermal tumor 6 | 3,031
Carcinoma 5 | 2,147
colon cancer 5 | 1,475
ependymoma 5 | 2,514
group 3 medulloblastoma 5 | 2,254
group 4 medulloblastoma 5 | 1,875
oligodendroglioma 5 | 2,849
Intellectual disability 4 | 573
astrocytic glioma 4 | 2,241
cystic fibrosis 4 | 1,670
pancreatic cancer 4 | 2,300
pituitary cancer 4 | 1,972
spina bifida 4 | 1,064
ulcerative colitis 4 | 2,087
Bipolar Disorder 3 | 266
Melanoma 3 | 261
Multiple Sclerosis 3 | 498
Multiple myeloma 3 | 1,327
Pick disease 3 | 1,893
Wiskott-Aldrich syndrome 3 | 27
acute quadriplegic myopathy 3 | 1,157
adrenocortical carcinoma 3 | 1,427
cutaneous lupus erythematosus 3 | 1,056
dermatomyositis 3 | 966
esophageal adenocarcinoma 3 | 737
medulloblastoma 3 | 1,524
non-small cell lung carcinoma 3 | 413
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,795
posterior fossa group A ependymoma 3 | 1,511
primary Sjogren syndrome 3 | 788
sonic hedgehog group medulloblastoma 3 | 1,482
Albuminuria 2 | 20
Attention deficit hyperactivity disorder 2 | 156
Liver carcinoma 2 | 217
Major Depressive Disorder 2 | 106
Microphthalmia 2 | 79
Nephrotic Syndrome 2 | 48
Prostatic Neoplasms 2 | 471
Proteinuria 2 | 63
Rheumatoid Arthritis 2 | 1,170
Schizophrenia 2 | 503
Skin cancer 2 | 37
Substance-Related Disorders 2 | 114
active ulcerative colitis 2 | 477
acute myeloid leukemia 2 | 785
atypical teratoid/rhabdoid tumor 2 | 1,095
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 499
chronic lymphocytic leukemia 2 | 244
diabetes mellitus 2 | 1,663
fibroadenoma 2 | 557
gastric carcinoma 2 | 832
juvenile dermatomyositis 2 | 1,189
mucosa-associated lymphoid tissue lymphoma 2 | 480
nasopharyngeal carcinoma 2 | 1,056
pancreatic carcinoma 2 | 567
post-traumatic stress disorder 2 | 45
posterior fossa group B ependymoma 2 | 1,530
progressive supranuclear palsy 2 | 674
tuberculosis and treatment for 6 months 2 | 686
Agoraphobia 1 | 16
Carcinoma of thyroid 1 | 17
Cholera 1 | 33
Congenital dyserythropoietic anemia 1 | 17
Diarrhea 1 | 155
Intestinal obstruction 1 | 16
Keshan disease 1 | 14
Kidney cancer 1 | 121
Liver cell carcinoma 1 | 15
Lymphoid leukemia 1 | 69
Nicotine dependence 1 | 53
Papillary thyroid carcinoma 1 | 37
Relapsing remitting multiple sclerosis 1 | 14
axial spondyloarthropathy 1 | 28
non-syndromic X-linked intellectual disability 1 | 21

Tissue

Blood and immune system 29 | 17,994
Cardiovascular System 29 | 17,957
Digestive Tract 29 | 18,472
Endocrine System 29 | 18,511
Female tissues 29 | 18,646
Liver and Pancreas 29 | 18,135
Male tissues 29 | 17,968
Nervous System 29 | 18,560
Respiratory system 29 | 17,483
Urinary Tract 29 | 18,443
Skin and soft tissues 28 | 18,114

Target Family

Non-IDG 24 | 11,969
Enzyme 3 | 4,146
GPCR 1 | 408
Kinase 1 | 634

GO Process

lamellipodium assembly 29 | 29
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 367 | 367
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
chemical synaptic transmission 238 | 238
MAPK cascade 237 | 237
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 199 | 199
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 180 | 180
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 175 | 175
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
protein folding 162 | 162
negative regulation of canonic... 161 | 161
response to lipopolysaccharide 161 | 161
T cell receptor signaling path... 160 | 160
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2-M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
type I interferon signaling pa... 130 | 130
endocytosis 129 | 129

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Guanine nucleotide exchange factor VAV2 VAV2 Tbio Non-IDG -1.78476 58.3 173
Cytoplasmic protein NCK2 NCK2 Tbio Non-IDG -1.56739 34.8 215
Wiskott-Aldrich syndrome protein family member 2 WASF2 Tbio Non-IDG -2.86162 683.7 211
Ras-related C3 botulinum toxin substrate 1 RAC1 Tbio Enzyme -1.87449 73.5 395
Actin-binding LIM protein 3 ABLIM3 Tbio Non-IDG -0.22185 2.18 104
Nuclear pore complex protein Nup85 NUP85 Tbio Non-IDG -1.18826 15.9 128
Rho guanine nucleotide exchange factor 4 ARHGEF4 Tbio Non-IDG -1.35105 25.1 107
SH2B adapter protein 1 SH2B1 Tbio Non-IDG -1.75534 59.8 189
Cytoplasmic FMR1-interacting protein 1 CYFIP1 Tbio Non-IDG -1.41078 26.7 55
Actin-binding LIM protein 1 ABLIM1 Tbio Non-IDG -1.05179 10.8 111