Development Level

Tbio 20 | 11,445
Tclin 12 | 613
Tchem 10 | 1,598

IMPC Phenotype

abnormal behavior 4 | 298
preweaning lethality, incomple... 3 | 499
abnormal bone structure 2 | 187
abnormal eye morphology 2 | 68
decreased body length 2 | 101
decreased mean corpuscular hem... 2 | 31
decreased total body fat amoun... 2 | 207
decreased vertical activity 2 | 208
embryonic lethality prior to o... 2 | 239
abnormal behavioral response t... 1 | 66
abnormal embryo size 1 | 220
abnormal eye anterior chamber ... 1 | 9
abnormal forebrain development 1 | 20
abnormal heart morphology 1 | 162
abnormal neural tube closure 1 | 46
abnormal placenta size 1 | 20
abnormal sleep behavior 1 | 70
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased grip strength 1 | 116
decreased heart weight 1 | 27
decreased hemoglobin content 1 | 68
decreased lean body mass 1 | 135
decreased mean corpuscular hem... 1 | 50
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
enlarged uterus 1 | 11
hydrometra 1 | 53
hyperactivity 1 | 148
hypoactivity 1 | 132
improved glucose tolerance 1 | 79
increased body weight 1 | 25
increased bone mineral content 1 | 108
increased circulating sodium l... 1 | 71
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
pale yolk sac 1 | 25
pallor 1 | 34
prenatal lethality prior to he... 1 | 87
preweaning lethality, complete... 1 | 979
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
small superior vagus ganglion 1 | 74
thrombocytopenia 1 | 56

Disease

Carcinoma 32 | 11,493
Cancer 22 | 2,499
medulloblastoma, large-cell 22 | 6,241
osteosarcoma 22 | 7,950
ovarian cancer 21 | 8,520
psoriasis 20 | 6,694
glioblastoma 18 | 5,792
lung cancer 18 | 4,740
Breast cancer 16 | 3,578
malignant mesothelioma 16 | 3,232
atypical teratoid / rhabdoid tumor 15 | 5,112
Astrocytoma, Pilocytic 13 | 3,081
adult high grade glioma 13 | 3,801
ependymoma 13 | 4,679
Schizophrenia 12 | 1,160
diabetes mellitus 12 | 1,728
invasive ductal carcinoma 12 | 2,951
Autosomal recessive predisposition 11 | 1,442
Major Depressive Disorder 11 | 301
ductal carcinoma in situ 11 | 1,745
group 3 medulloblastoma 11 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,291
lung adenocarcinoma 11 | 2,716
primitive neuroectodermal tumor 11 | 3,035
Anemia 10 | 365
pituitary cancer 10 | 1,972
Breast Neoplasms 9 | 445
Mammary Neoplasms 9 | 425
Mammary Neoplasms, Experimental 9 | 154
Prostatic Neoplasms 9 | 495
pancreatic cancer 9 | 2,398
ulcerative colitis 9 | 1,819
Depressive disorder 8 | 409
Hypertension 8 | 396
Kidney cancer 8 | 2,613
lung carcinoma 8 | 2,843
non-small cell lung cancer 8 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,962
Animal Mammary Neoplasms 7 | 136
Bipolar Disorder 7 | 666
Mammary Neoplasms, Animal 7 | 136
Mental Depression 7 | 333
Obesity 7 | 678
Unipolar Depression 7 | 250
breast carcinoma 7 | 1,638
cystic fibrosis 7 | 1,696
Colorectal Neoplasms 6 | 243
Endometriosis 6 | 540
acute quadriplegic myopathy 6 | 1,158
aldosterone-producing adenoma 6 | 665
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
tuberculosis 6 | 2,010
Adenocarcinoma 5 | 122
Arthritis 5 | 290
Carcinoma, Hepatocellular 5 | 228
Disease Models, Animal 5 | 155
Heart disease 5 | 306
Heart failure 5 | 162
Hypertensive disease 5 | 292
Kidney disease 5 | 430
Liver Cirrhosis, Experimental 5 | 769
Liver carcinoma 5 | 240
Mood Disorders 5 | 184
Myocardial Ischemia 5 | 169
Pick disease 5 | 1,894
Short stature 5 | 531
astrocytoma 5 | 1,146
dermatomyositis 5 | 966
fibroadenoma 5 | 559
nasopharyngeal carcinoma 5 | 1,058
primary pancreatic ductal adenocarcinoma 5 | 1,109
subependymal giant cell astrocytoma 5 | 2,287
Adenoma 4 | 167
Amyotrophic lateral sclerosis 4 | 451
Atherosclerosis 4 | 291
Autistic Disorder 4 | 364
Bone pain 4 | 42
Colonic Neoplasms 4 | 142
Dementia 4 | 175
Diabetes Mellitus, Non-Insulin-Dependent 4 | 145
Fatigue 4 | 182
Hemoglobin low 4 | 124
Liver Neoplasms, Experimental 4 | 59
Liver cancer 4 | 604
Neoplasm Metastasis 4 | 168
Nephrolithiasis 4 | 56
Neurodegenerative disease 4 | 414
Osteoporosis 4 | 363
Pancreatitis 4 | 123
Rheumatoid arthritis 4 | 1,191
Splenomegaly 4 | 190
Vascular disease 4 | 319
astrocytic glioma 4 | 2,597
colon cancer 4 | 1,478
group 4 medulloblastoma 4 | 1,855
oligodendroglioma 4 | 2,850
adrenocortical carcinoma 3 | 1,428
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
chronic rhinosinusitis 3 | 512

Tissue

Endocrine System 42 | 18,159
Female tissues 41 | 17,400
Digestive Tract 40 | 17,369
Male tissues 39 | 17,142
Skin and soft tissues 39 | 17,230
Blood and immune system 38 | 16,909
Liver and Pancreas 38 | 16,750
Urinary Tract 38 | 16,678
Respiratory system 36 | 16,393
Cardiovascular System 35 | 15,192
Nervous System 35 | 16,725

Target Family

Enzyme 16 | 4,145
Non-IDG 8 | 12,091
Transcription Factor 6 | 1,400
Kinase 5 | 634
Transporter 3 | 473
GPCR 2 | 408
Epigenetic 1 | 242
Nuclear Receptor 1 | 48

GO Process

lactation 42 | 42
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Forkhead box protein B1 FOXB1 Tbio Transcription Factor -1.17019 15.7 110
E3 ubiquitin-protein ligase NEURL1 NEURL1 Tbio Enzyme -1.09204 13.1 165
Hexokinase-2 HK2 Tchem Kinase -2.64934 432.5 446
Epithelial discoidin domain-containing receptor 1 DDR1 Tchem Kinase -2.26801 0.00000 534
Nucleoside diphosphate kinase A NME1 Tbio Kinase -2.99077 863.1 945
Sodium-dependent dopamine transporter SLC6A3 Tclin Transporter -3.59848 3752.4 324
Xanthine dehydrogenase/oxidase XDH Tclin Enzyme -2.69810 506.6 179
Peptidyl-glycine alpha-amidating monooxygenase PAM Tchem Enzyme -2.61669 398.2 81
Dihydroorotate dehydrogenase (quinone), mitochondrial DHODH Tclin Enzyme -2.47702 295.8 225
Receptor tyrosine-protein kinase erbB-4 ERBB4 Tclin Kinase -2.78704 558.2 1072