Development Level

Tbio 6 | 11,445
Tclin 1 | 613

IMPC Phenotype

abnormal cornea morphology 1 | 31
abnormal lens morphology 1 | 81
abnormal optic disc morphology 1 | 10
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
cataract 1 | 92
corneal opacity 1 | 32
decreased lean body mass 1 | 135
fused cornea and lens 1 | 5
impaired pupillary reflex 1 | 26
increased circulating HDL chol... 1 | 80
increased circulating choleste... 1 | 66
increased total body fat amoun... 1 | 134
iris synechia 1 | 3
narrow eye opening 1 | 12
persistence of hyaloid vascula... 1 | 33
preweaning lethality, complete... 1 | 979

Disease

Breast cancer 5 | 3,578
Carcinoma 5 | 11,493
medulloblastoma, large-cell 5 | 6,241
Cancer 4 | 2,499
Congenital deafness 4 | 185
Cryptorchidism 4 | 296
Deafness 4 | 198
Hearing Loss, Partial 4 | 185
Orbital separation excessive 4 | 244
glioblastoma 4 | 5,792
group 3 medulloblastoma 4 | 4,104
hearing impairment 4 | 199
lung adenocarcinoma 4 | 2,716
osteosarcoma 4 | 7,950
Alacrima 3 | 9
Alzheimer's disease 3 | 658
Astrocytoma, Pilocytic 3 | 3,081
Autosomal recessive predisposition 3 | 1,442
Cleft Palate 3 | 271
Cognitive delay 3 | 608
Craniofacial Abnormalities 3 | 151
Down syndrome 3 | 499
Dull intelligence 3 | 645
Exophthalmos 3 | 112
Global developmental delay 3 | 608
Hydrocephalus 3 | 152
Hypodontia 3 | 81
Hypoplastic mandible condyle 3 | 275
Hypospadias 3 | 53
Intellectual disability 3 | 1,016
Lacrimal Duct Obstruction 3 | 16
Low intelligence 3 | 645
Mandibular hypoplasia 3 | 275
Mental Retardation 3 | 645
Mental and motor retardation 3 | 608
Mental deficiency 3 | 645
Micrognathism 3 | 275
Muscle hypotonia 3 | 571
Nystagmus 3 | 317
Poor school performance 3 | 645
Prominent eyes 3 | 96
Prominent globes 3 | 96
Protruding eyes 3 | 96
Schizophrenia 3 | 1,160
Short stature 3 | 531
Telecanthus 3 | 62
adult high grade glioma 3 | 3,801
breast carcinoma 3 | 1,638
ependymoma 3 | 4,679
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
invasive ductal carcinoma 3 | 2,951
lung cancer 3 | 4,740
malignant mesothelioma 3 | 3,232
nephrosclerosis 3 | 333
oligodendroglioma 3 | 2,850
ovarian cancer 3 | 8,520
pituitary cancer 3 | 1,972
psoriasis 3 | 6,694
Abnormal vision 2 | 52
Abnormality of vision 2 | 40
Absence of radius and ulna 2 | 15
Absent radius 2 | 15
Atrial Septal Defects 2 | 85
Breast Neoplasms 2 | 445
Capuchin ears 2 | 17
Congenital Heart Defects 2 | 58
Congenital heart disease 2 | 93
Convex nasal bridge 2 | 57
Cupped ears (finding) 2 | 17
Decreased projection of midface 2 | 105
Defective enamel matrix 2 | 35
Delayed Puberty 2 | 97
Dental Enamel Hypoplasia 2 | 43
Dental caries 2 | 164
Dysplasia of tooth enamel 2 | 35
Esophageal atresia 2 | 43
Hearing abnormality 2 | 12
Hypogonadism, Isolated Hypogonadotropic 2 | 71
Hypogonadotropic hypogonadism 2 | 89
Hypotrophic malar bone 2 | 129
Hypotrophic midface 2 | 105
Malar flattening 2 | 129
Mammary Neoplasms 2 | 425
Microphthalmia 2 | 76
Midface retrusion 2 | 105
Narrow thorax 2 | 53
Peg shaped front tooth 2 | 6
Peg-shaped incisors 2 | 6
Pointed front tooth 2 | 6
Pointed incisor 2 | 6
Prominent nasal bridge 2 | 57
Radial aplasia 2 | 15
Respiratory distress 2 | 43
Rotting teeth 2 | 73
Small midface 2 | 105
Small testicle 2 | 75
Somatic mutation 2 | 61
Streak ovary 2 | 15
Thin dental enamel 2 | 35
Tooth Abnormalities 2 | 69

Tissue

Blood and immune system 7 | 16,909
Digestive Tract 7 | 17,369
Endocrine System 7 | 18,159
Female tissues 7 | 17,400
Liver and Pancreas 7 | 16,750
Male tissues 7 | 17,142
Nervous System 7 | 16,725
Skin and soft tissues 7 | 17,230
Urinary Tract 7 | 16,678
Cardiovascular System 6 | 15,192
Respiratory system 6 | 16,393

Target Family

Transcription Factor 4 | 1,400
Non-IDG 2 | 12,091
Kinase 1 | 634

GO Process

lacrimal gland development 7 | 7
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Paired box protein Pax-6 PAX6 Tbio Transcription Factor -3.16650 1458.6 570
Immunoglobulin superfamily member 3 IGSF3 Tbio Non-IDG -1.56953 37.0 118
Forkhead box protein C1 FOXC1 Tbio Transcription Factor -2.28586 201.8 314
Transcription factor SOX-10 SOX10 Tbio Transcription Factor -2.69195 478.2 389
Transcription factor SOX-9 SOX9 Tbio Transcription Factor -3.14522 1332.4 657
Fibroblast growth factor 10 FGF10 Tbio Non-IDG -2.55166 363.0 320
Fibroblast growth factor receptor 2 FGFR2 Tclin Kinase -3.08664 1210.6 948