Development Level

Tbio 63 | 11,445
Tchem 10 | 1,598
Tclin 9 | 613
Tdark 4 | 6,588

Collection

Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

preweaning lethality, complete... 10 | 979
abnormal seminal vesicle morph... 5 | 114
abnormal embryo size 4 | 220
preweaning lethality, incomple... 4 | 499
abnormal heart morphology 3 | 162
enlarged heart 3 | 210
abnormal eye morphology 2 | 68
abnormal kidney morphology 2 | 65
abnormal neural tube closure 2 | 46
abnormal spleen morphology 2 | 55
abnormal testis morphology 2 | 43
decreased body length 2 | 101
decreased circulating HDL chol... 2 | 68
decreased circulating alkaline... 2 | 46
decreased circulating choleste... 2 | 93
decreased lymphocyte cell numb... 2 | 83
decreased vertical activity 2 | 208
edema 2 | 59
embryonic growth retardation 2 | 106
embryonic lethality prior to t... 2 | 278
hydrometra 2 | 53
increased circulating chloride... 2 | 41
small superior vagus ganglion 2 | 74
abnormal body wall morphology 1 | 9
abnormal craniofacial morpholo... 1 | 33
abnormal facial morphology 1 | 17
abnormal hindbrain morphology 1 | 10
abnormal limb bud morphology 1 | 17
abnormal limb morphology 1 | 13
abnormal liver morphology 1 | 17
abnormal midbrain morphology 1 | 10
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal skin morphology 1 | 50
abnormal tail morphology 1 | 25
abnormal vibrissa morphology 1 | 25
cleft palate 1 | 8
decreased NK T cell number 1 | 2
decreased anxiety-related resp... 1 | 12
decreased body temperature 1 | 2
decreased circulating glucose ... 1 | 126
decreased circulating total pr... 1 | 49
decreased lactate dehydrogenas... 1 | 16
decreased startle reflex 1 | 75
embryonic lethality prior to o... 1 | 239
enlarged seminal vesicle 1 | 10
enlarged spleen 1 | 41
enlarged testis 1 | 6
hemorrhage 1 | 23
hydroencephaly 1 | 14
increased circulating alkaline... 1 | 122
increased circulating creatini... 1 | 38
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 42
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased neutrophil cell numb... 1 | 46
increased startle reflex 1 | 112
pale yolk sac 1 | 25
pallor 1 | 34
prolonged ST segment 1 | 36
scaly skin 1 | 4
small testis 1 | 58

Disease

Carcinoma 64 | 11,493
ovarian cancer 46 | 8,520
lung cancer 43 | 4,740
medulloblastoma, large-cell 41 | 6,241
osteosarcoma 41 | 7,950
psoriasis 38 | 6,694
Cancer 35 | 2,499
lung adenocarcinoma 31 | 2,716
glioblastoma 30 | 5,792
non-small cell lung cancer 30 | 2,890
Breast cancer 28 | 3,578
invasive ductal carcinoma 28 | 2,951
atypical teratoid / rhabdoid tumor 27 | 5,112
pancreatic cancer 27 | 2,398
malignant mesothelioma 25 | 3,232
ependymoma 24 | 4,679
intraductal papillary-mucinous neoplasm (IPMN) 22 | 3,291
group 3 medulloblastoma 21 | 4,104
lung carcinoma 21 | 2,843
primitive neuroectodermal tumor 21 | 3,035
adult high grade glioma 20 | 3,801
cystic fibrosis 20 | 1,696
intraductal papillary-mucinous adenoma (IPMA) 20 | 2,955
Autosomal recessive predisposition 19 | 1,442
ductal carcinoma in situ 19 | 1,745
breast carcinoma 18 | 1,638
colon cancer 18 | 1,478
interstitial cystitis 17 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 17 | 2,989
Astrocytoma, Pilocytic 16 | 3,081
Kidney disease 16 | 430
pituitary cancer 16 | 1,972
Kidney cancer 15 | 2,613
Short stature 15 | 531
Kidney Diseases 13 | 114
adrenocortical carcinoma 13 | 1,428
Small head 12 | 374
cutaneous lupus erythematosus 12 | 1,057
ulcerative colitis 12 | 1,819
Hypertensive disease 11 | 292
astrocytic glioma 11 | 2,597
diabetes mellitus 11 | 1,728
oligodendroglioma 11 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 11 | 1,962
tuberculosis 11 | 2,010
Atopic dermatitis 10 | 952
Intellectual disability 10 | 1,016
Maternal oligohydramnios 10 | 31
Oligohydramnios 10 | 52
Orbital separation excessive 10 | 244
Prostatic Neoplasms 10 | 495
Renal Insufficiency 10 | 90
primary pancreatic ductal adenocarcinoma 10 | 1,109
spina bifida 10 | 1,074
Cataract 9 | 297
Cognitive delay 9 | 608
Coronary artery disease 9 | 268
Cryptorchidism 9 | 296
Dull intelligence 9 | 645
Global developmental delay 9 | 608
Hypoplastic mandible condyle 9 | 275
Kidney Failure 9 | 111
Low intelligence 9 | 645
Mandibular hypoplasia 9 | 275
Mental Retardation 9 | 645
Mental and motor retardation 9 | 608
Mental deficiency 9 | 645
Micrognathism 9 | 275
Obesity 9 | 678
Patent ductus arteriosus 9 | 90
Poor school performance 9 | 645
active ulcerative colitis 9 | 764
acute quadriplegic myopathy 9 | 1,158
gastric carcinoma 9 | 807
Alzheimer's disease 8 | 658
Blepharoptosis 8 | 231
Breast Neoplasms 8 | 445
Cleft Palate 8 | 271
Congenital hypoplasia of lung 8 | 48
Endometriosis 8 | 540
Nystagmus 8 | 317
Pick disease 8 | 1,894
Renal dysplasia 8 | 28
Rheumatoid arthritis 8 | 1,191
aldosterone-producing adenoma 8 | 665
astrocytoma 8 | 1,146
group 4 medulloblastoma 8 | 1,855
subependymal giant cell astrocytoma 8 | 2,287
Atherosclerosis 7 | 291
Cerebrovascular disease 7 | 238
Depressed nasal ridge 7 | 51
Down syndrome 7 | 499
Epilepsy 7 | 792
Glaucoma 7 | 239
Hypertension 7 | 396
Increase in blood pressure 7 | 119
Seizures 7 | 596
chronic rhinosinusitis 7 | 512
fibroadenoma 7 | 559
nephrosclerosis 7 | 333

Tissue

Digestive Tract 86 | 17,369
Endocrine System 85 | 18,159
Female tissues 85 | 17,400
Skin and soft tissues 85 | 17,230
Urinary Tract 84 | 16,678
Liver and Pancreas 83 | 16,750
Male tissues 83 | 17,142
Respiratory system 83 | 16,393
Blood and immune system 82 | 16,909
Nervous System 79 | 16,725
Cardiovascular System 76 | 15,192

Target Family

Non-IDG 32 | 12,091
Enzyme 26 | 4,145
Transcription Factor 20 | 1,400
Epigenetic 2 | 242
Ion Channel 2 | 344
Kinase 2 | 634
GPCR 1 | 408
Transporter 1 | 473

GO Process

kidney development 86 | 86
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Notchless protein homolog 1 NLE1 Tbio Non-IDG -2.69934 437.6 162
Pentatricopeptide repeat-containing protein 2, mitochondrial PTCD2 Tdark Non-IDG -0.06695 1.01 131
WD repeat-containing and planar cell polarity effector protein fritz homolog WDPCP Tbio Non-IDG -0.84019 7.08 68
A disintegrin and metalloproteinase with thrombospondin motifs 1 ADAMTS1 Tchem Enzyme -2.44459 279.8 227
AT-rich interactive domain-containing protein 5B ARID5B Tbio Transcription Factor -1.71561 54.6 97
Extracellular sulfatase Sulf-2 SULF2 Tbio Enzyme -1.74398 67.0 221
Extracellular sulfatase Sulf-1 SULF1 Tbio Enzyme -1.90276 92.2 61
Centromere protein F CENPF Tbio Non-IDG -2.02939 109.1 186
15-hydroxyprostaglandin dehydrogenase [NAD(+)] HPGD Tchem Enzyme -2.26841 191.0 354
Receptor for retinol uptake STRA6 STRA6 Tbio Non-IDG -1.78205 67.9 157