Development Level

Tbio 43 | 11,445
Tdark 19 | 6,588
Tchem 8 | 1,598
Tclin 2 | 613

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 5 | 979
abnormal bone structure 2 | 187
abnormal embryo size 2 | 220
abnormal eye morphology 2 | 68
abnormal heart morphology 2 | 162
abnormal kidney morphology 2 | 65
abnormal placenta size 2 | 20
embryonic growth retardation 2 | 106
enlarged heart 2 | 210
hydrometra 2 | 53
hypoactivity 2 | 132
increased monocyte cell number 2 | 63
pale yolk sac 2 | 25
pallor 2 | 34
preweaning lethality, incomple... 2 | 499
small superior vagus ganglion 2 | 74
abnormal forebrain development 1 | 20
abnormal hair growth 1 | 10
abnormal lens morphology 1 | 81
abnormal limb bud morphology 1 | 17
abnormal liver size 1 | 5
abnormal neural tube closure 1 | 46
abnormal retina morphology 1 | 71
abnormal retinal vasculature m... 1 | 27
abnormal seminal vesicle morph... 1 | 114
abnormal skin morphology 1 | 50
abnormal thymus morphology 1 | 7
abnormal vertebrae morphology 1 | 18
abnormal vibrissa morphology 1 | 25
athymia 1 | 2
cataract 1 | 92
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased lymphocyte cell numb... 1 | 83
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged uterus 1 | 11
hyperactivity 1 | 148
improved glucose tolerance 1 | 79
increased circulating calcium ... 1 | 34
increased fasted circulating g... 1 | 76
increased hemoglobin content 1 | 45
increased total body fat amoun... 1 | 134
increased total retina thickne... 1 | 4
male infertility 1 | 123
pale liver 1 | 6
persistence of hyaloid vascula... 1 | 33
prenatal lethality prior to he... 1 | 87
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
thrombocytopenia 1 | 56

Disease

psoriasis 40 | 6,694
Carcinoma 31 | 11,493
ovarian cancer 26 | 8,520
Cancer 24 | 2,499
lung cancer 24 | 4,740
osteosarcoma 20 | 7,950
Atopic dermatitis 19 | 952
non-small cell lung cancer 19 | 2,890
pancreatic cancer 19 | 2,398
medulloblastoma, large-cell 18 | 6,241
diabetes mellitus 16 | 1,728
Breast cancer 15 | 3,578
cystic fibrosis 15 | 1,696
glioblastoma 15 | 5,792
interstitial cystitis 14 | 2,312
esophageal adenocarcinoma 13 | 737
intraductal papillary-mucinous neoplasm (IPMN) 12 | 3,291
Kidney cancer 11 | 2,613
atypical teratoid / rhabdoid tumor 11 | 5,112
ependymoma 11 | 4,679
invasive ductal carcinoma 11 | 2,951
cutaneous lupus erythematosus 10 | 1,057
lung carcinoma 10 | 2,843
Rheumatoid arthritis 9 | 1,191
adult high grade glioma 9 | 3,801
breast carcinoma 9 | 1,638
ductal carcinoma in situ 9 | 1,745
malignant mesothelioma 9 | 3,232
nasopharyngeal carcinoma 9 | 1,058
Astrocytoma, Pilocytic 8 | 3,081
Autosomal recessive predisposition 8 | 1,442
Palmoplantar keratosis 8 | 74
astrocytoma 8 | 1,146
dermatomyositis 8 | 966
group 4 medulloblastoma 8 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
lung adenocarcinoma 8 | 2,716
Carcinoma, Squamous Cell 7 | 110
Cryptorchidism 7 | 296
Epidermolytic hyperkeratosis 7 | 14
Melanoma 7 | 711
Skin cancer 7 | 469
oligodendroglioma 7 | 2,850
spina bifida 7 | 1,074
ulcerative colitis 7 | 1,819
Amyotrophic lateral sclerosis 6 | 451
Congenital ichthyosiform erythroderma 6 | 28
Failure to gain weight 6 | 365
Ichthyoses 6 | 41
Ichthyosis 6 | 56
Ichthyosis vulgaris 6 | 11
Keratosis 6 | 37
Pediatric failure to thrive 6 | 365
Squamous cell carcinoma 6 | 129
acute quadriplegic myopathy 6 | 1,158
autosomal dominant Emery-Dreifuss muscular dystrophy 6 | 510
group 3 medulloblastoma 6 | 4,104
pituitary cancer 6 | 1,972
primitive neuroectodermal tumor 6 | 3,035
tuberculosis 6 | 2,010
Alzheimer's disease 5 | 658
Brachydactyly 5 | 156
Cataract 5 | 297
Craniofacial Abnormalities 5 | 151
Erythema 5 | 58
Flushing 5 | 60
Hypoplastic mandible condyle 5 | 275
Liver cancer 5 | 604
Mandibular hypoplasia 5 | 275
Micrognathism 5 | 275
Pick disease 5 | 1,894
Prostatic Neoplasms 5 | 495
Sparse hair 5 | 59
Strabismus 5 | 270
Thin, sparse hair 5 | 59
aldosterone-producing adenoma 5 | 665
atypical teratoid/rhabdoid tumor 5 | 357
juvenile dermatomyositis 5 | 1,187
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
periodontitis 5 | 293
primary pancreatic ductal adenocarcinoma 5 | 1,109
subependymal giant cell astrocytoma 5 | 2,287
Alopecia 4 | 115
Asthma 4 | 385
Duchenne muscular dystrophy 4 | 601
Dystrophia unguium 4 | 53
Endometriosis 4 | 540
Hypotrichosis 4 | 47
Lens Opacities 4 | 231
Myopia 4 | 176
Neoplastic Cell Transformation 4 | 89
Osteoarthritis 4 | 184
Schizophrenia 4 | 1,160
Short stature 4 | 531
Syndactyly of fingers 4 | 48
astrocytic glioma 4 | 2,597
colon cancer 4 | 1,478
fibroadenoma 4 | 559
head and neck cancer 4 | 271
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989

Tissue

Skin and soft tissues 70 | 17,230
Female tissues 67 | 17,400
Blood and immune system 63 | 16,909
Digestive Tract 61 | 17,369
Endocrine System 56 | 18,159
Urinary Tract 48 | 16,678
Liver and Pancreas 46 | 16,750
Male tissues 44 | 17,142
Nervous System 44 | 16,725
Cardiovascular System 39 | 15,192
Respiratory system 38 | 16,393

Target Family

Non-IDG 52 | 12,091
Enzyme 7 | 4,145
Transcription Factor 7 | 1,400
Kinase 5 | 634
Ion Channel 1 | 344

GO Process

keratinocyte differentiation 72 | 72
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Suppressor of tumorigenicity 14 protein ST14 Tchem Non-IDG -2.50215 338.3 309
Small proline-rich protein 2F SPRR2F Tbio Non-IDG 0.44 0.31 12
Tumor susceptibility gene 101 protein TSG101 Tbio Non-IDG -2.47780 298.9 332
Small proline-rich protein 4 SPRR4 Tdark Non-IDG -0.32647 2.13 9
Disintegrin and metalloproteinase domain-containing protein 9 ADAM9 Tchem Enzyme -2.08807 122.3 258
Dual specificity mitogen-activated protein kinase kinase 1 MAP2K1 Tclin Kinase -3.07197 862.4 2448
Late cornified envelope protein 3D LCE3D Tdark Non-IDG -0.13175 1.11 0
Late cornified envelope protein 5A LCE5A Tdark Non-IDG 0.50 0.32 0
Small proline-rich protein 2G SPRR2G Tbio Non-IDG 0.39 0.31 1
Paired box protein Pax-6 PAX6 Tbio Transcription Factor -3.16650 1458.6 570