Development Level

Tbio 9 | 11,445
Tchem 1 | 1,598

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal cranium morphology 1 | 36
abnormal embryo size 1 | 220
abnormal eyelid fusion 1 | 3
abnormal facial morphology 1 | 17
abnormal kidney morphology 1 | 65
abnormal retina morphology 1 | 71
decreased bone mineral content 1 | 151
decreased circulating serum al... 1 | 82
decreased lean body mass 1 | 135
decreased neutrophil cell numb... 1 | 42
decreased red blood cell distr... 1 | 41
decreased spleen weight 1 | 10
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged kidney 1 | 14
hemorrhage 1 | 23
increased circulating alkaline... 1 | 122
increased fasted circulating g... 1 | 76
increased neutrophil cell numb... 1 | 46
increased spleen weight 1 | 10
increased startle reflex 1 | 112
increased vertical activity 1 | 24
preweaning lethality, incomple... 1 | 499
short tibia 1 | 97

Disease

Carcinoma 9 | 11,493
atypical teratoid / rhabdoid tumor 8 | 5,112
ependymoma 8 | 4,679
lung cancer 6 | 4,740
osteosarcoma 6 | 7,950
ovarian cancer 6 | 8,520
glioblastoma 5 | 5,792
interstitial cystitis 5 | 2,312
medulloblastoma, large-cell 5 | 6,241
pancreatic cancer 5 | 2,398
psoriasis 5 | 6,694
Astrocytoma, Pilocytic 4 | 3,081
Cancer 4 | 2,499
astrocytic glioma 4 | 2,597
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
lung carcinoma 4 | 2,843
oligodendroglioma 4 | 2,850
spina bifida 4 | 1,074
Breast cancer 3 | 3,578
Intellectual disability 3 | 1,016
Pick disease 3 | 1,894
adult high grade glioma 3 | 3,801
chronic rhinosinusitis 3 | 512
ductal carcinoma in situ 3 | 1,745
malignant mesothelioma 3 | 3,232
non-small cell lung cancer 3 | 2,890
pediatric high grade glioma 3 | 1,064
Autosomal recessive predisposition 2 | 1,442
Kidney cancer 2 | 2,613
Schizophrenia 2 | 1,160
active Crohn's disease 2 | 922
adrenocortical carcinoma 2 | 1,428
cutaneous lupus erythematosus 2 | 1,057
cystic fibrosis 2 | 1,696
gastric cancer 2 | 459
group 4 medulloblastoma 2 | 1,855
hepatocellular carcinoma 2 | 547
invasive ductal carcinoma 2 | 2,951
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
periodontitis 2 | 293
pituitary cancer 2 | 1,972
primitive neuroectodermal tumor 2 | 3,035
sarcoidosis 2 | 370
subependymal giant cell astrocytoma 2 | 2,287
tuberculosis 2 | 2,010
11 pairs of ribs 1 | 7
Aarskog syndrome 1 | 12
Abnormality of the humerus 1 | 6
Abnormality of the metacarpal bones 1 | 17
Abnormality of the tibia 1 | 9
Adams-Oliver syndrome 1 | 15
Adenocarcinoma of lung (disorder) 1 | 60
Adrenal Gland Neoplasms 1 | 11
Aplasia/Hypoplasia of the abdominal wall musculature 1 | 17
Beaked vertebral bodies 1 | 9
Benign breast adenomyoepithelioma 1 | 2
Brachyonychia 1 | 6
Broad distal phalanges 1 | 2
Broad face 1 | 7
Bronchomalacia 1 | 7
Chromoblastomycosis 1 | 10
Clostridium difficile colitis 1 | 12
Compression of spinal cord 1 | 10
Congenital ichthyosiform erythroderma 1 | 28
Congenital pectus carinatum 1 | 52
Coronal cleft vertebrae 1 | 8
Epiphyseal dysplasia 1 | 14
Equinovalgus deformity 1 | 4
Flat acetabular roof 1 | 10
Graves' disease 1 | 24
Hearing Loss, Mixed Conductive-Sensorineural 1 | 12
Hitchhiker thumb 1 | 3
Horizontal sacrum 1 | 3
Hyperkeratosis, Epidermolytic 1 | 7
Hypoplastic iliac body 1 | 2
Isolated somatotropin deficiency 1 | 30
Joint laxity 1 | 54
Kindler syndrome 1 | 11
Larsen syndrome 1 | 10
Lymphatic Metastasis 1 | 15
Neonatal Death 1 | 14
Popliteal pterygium syndrome 1 | 6
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 1 | 25
Restrictive lung disease 1 | 11
Sandal gap 1 | 24
Severe short-limb dwarfism 1 | 4
Shallow orbits 1 | 13
Short metatarsal 1 | 21
Spatulate thumbs 1 | 3
Spondyloepiphyseal dysplasia with congenital joint dislocations 1 | 13
Talipes Equinovalgus 1 | 4
Tarsal Coalition 1 | 12
Thin hypoplastic alae nasi 1 | 51
Tibial bowing 1 | 19
Tracheal stenosis 1 | 23
Type 1 diabetes mellitus 1 | 109
Wedging of vertebra 1 | 9
Wiskott-Aldrich syndrome 1 | 30

Tissue

Blood and immune system 10 | 16,909
Digestive Tract 10 | 17,369
Female tissues 10 | 17,400
Male tissues 10 | 17,142
Skin and soft tissues 10 | 17,230
Endocrine System 9 | 18,159
Liver and Pancreas 9 | 16,750
Respiratory system 9 | 16,393
Urinary Tract 9 | 16,678
Cardiovascular System 8 | 15,192
Nervous System 8 | 16,725

Target Family

Non-IDG 7 | 12,091
Transcription Factor 2 | 1,400
Enzyme 1 | 4,145

GO Process

keratinocyte development 10 | 10
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Palladin PALLD Tbio Non-IDG -2.73002 528.8 164
Keratinocyte differentiation factor 1 KDF1 Tbio Non-IDG -0.26977 2.27 78
Cell division control protein 42 homolog CDC42 Tchem Enzyme -3.37283 2188.5 380
Keratin, type II cytoskeletal 2 epidermal KRT2 Tbio Non-IDG -1.64971 43.0 144
Exophilin-5 EXPH5 Tbio Non-IDG -0.80277 6.39 25
Filamin-B FLNB Tbio Non-IDG -2.43075 263.4 168
B-cell lymphoma/leukemia 11B BCL11B Tbio Transcription Factor -2.10918 140.4 186
Fos-related antigen 2 FOSL2 Tbio Transcription Factor -2.16948 129.6 430
14-3-3 protein sigma SFN Tbio Non-IDG -2.56638 391.2 550
Intraflagellar transport protein 74 homolog IFT74 Tbio Non-IDG -0.79253 6.07 133