Development Level

Tbio 9 | 11,445
Tdark 3 | 6,588

Collection

Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

decreased erythrocyte cell num... 1 | 62
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
increased circulating iron lev... 1 | 30
increased mean corpuscular hem... 1 | 96
preweaning lethality, complete... 1 | 979
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36

Disease

Carcinoma 9 | 11,493
medulloblastoma, large-cell 6 | 6,241
psoriasis 6 | 6,694
atypical teratoid / rhabdoid tumor 5 | 5,112
osteosarcoma 5 | 7,950
Aceruloplasminemia 4 | 16
glioblastoma 4 | 5,792
group 3 medulloblastoma 4 | 4,104
lung cancer 4 | 4,740
non-small cell lung cancer 4 | 2,890
ovarian cancer 4 | 8,520
Anemia 3 | 365
Autosomal recessive predisposition 3 | 1,442
Breast cancer 3 | 3,578
Hemochromatosis 3 | 54
Hyperferritinaemia 3 | 14
Increased ferritin 3 | 14
Neoplasm Invasiveness 3 | 161
Neurodegeneration with brain iron accumulation 3 | 20
Serum ferritin increased 3 | 14
ependymoma 3 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
lung carcinoma 3 | 2,843
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
primitive neuroectodermal tumor 3 | 3,035
ulcerative colitis 3 | 1,819
Atransferrinemia 2 | 8
Cancer 2 | 2,499
Depressive disorder 2 | 409
Keloid 2 | 37
Mesothelioma, Malignant 2 | 105
Neurodegeneration with brain iron accumulation 3 2 | 8
Neurodegenerative Disorders 2 | 79
Rheumatoid arthritis 2 | 1,191
adrenocortical carcinoma 2 | 1,428
adult high grade glioma 2 | 3,801
astrocytic glioma 2 | 2,597
breast carcinoma 2 | 1,638
lung adenocarcinoma 2 | 2,716
malignant mesothelioma 2 | 3,232
oligodendroglioma 2 | 2,850
pancreatic cancer 2 | 2,398
pituitary cancer 2 | 1,972
subependymal giant cell astrocytoma 2 | 2,287
Beta thalassemia 1 | 16
Bowed and upward slanting eyebrows 1 | 41
Brucellosis 1 | 24
Cleft lip and alveolus 1 | 4
Cleft palate and bilateral cleft lip 1 | 4
Colitis, Ulcerative 1 | 59
Coughing 1 | 25
Cutaneous finger syndactyly 1 | 11
Decreased projection of midface 1 | 105
Decreased size of teeth 1 | 62
Decreased width of tooth 1 | 59
Degenerative disc disease 1 | 35
Depressed cheekbone 1 | 22
Developmental absence of tooth 1 | 7
Diabetes Mellitus, Insulin-Dependent 1 | 48
Diabetes Mellitus, Type 1 1 | 43
Dysphonia 1 | 7
Dystrophic fingernails 1 | 18
Flattening of the zygomatic bone 1 | 22
Food Hypersensitivity 1 | 3
Glomerulonephritis 1 | 46
Heredodegenerative Disorders, Nervous System 1 | 3
Herpes simplex 1 | 18
Human immunodeficiency virus infectious disease 1 | 138
Hypoplasia of scrotum 1 | 24
Hypoplasia of the zygomatic bone 1 | 22
Hypotrophic cheekbone 1 | 22
Hypotrophic midface 1 | 105
Inflammatory Bowel Diseases 1 | 35
Iron Metabolism Disorders 1 | 5
Juvenile rheumatoid arthritis 1 | 111
Laryngeal dystonia 1 | 5
Leishmaniasis, Visceral 1 | 13
Leprosy 1 | 73
Microdontia (disorder) 1 | 59
Midface retrusion 1 | 105
Muscle Rigidity 1 | 49
Mutism 1 | 17
Neurodegenerative Diseases 1 | 38
Nonorganic psychosis 1 | 84
Organic writer's cramp 1 | 10
Precancerous Conditions 1 | 80
Restless legs syndrome 1 | 27
Rotting teeth 1 | 73
Small cheekbone 1 | 22
Small midface 1 | 105
Sparse eyebrow 1 | 42
Sparse eyelashes 1 | 31
Syndactyly of fingers 1 | 48
Thick, flared eyebrows 1 | 41
Tularemia 1 | 23
Typhoid fever 1 | 22
Visceral leishmaniasis 1 | 14
Wide spaced nipples 1 | 46

Tissue

Endocrine System 11 | 18,159
Blood and immune system 9 | 16,909
Digestive Tract 9 | 17,369
Female tissues 9 | 17,400
Liver and Pancreas 9 | 16,750
Nervous System 9 | 16,725
Skin and soft tissues 9 | 17,230
Male tissues 8 | 17,142
Cardiovascular System 7 | 15,192
Respiratory system 7 | 16,393
Urinary Tract 7 | 16,678

Target Family

Non-IDG 9 | 12,091
Enzyme 1 | 4,145
Ion Channel 1 | 344
Transporter 1 | 473

GO Process

iron ion transport 12 | 12
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Hephaestin HEPH Tbio Non-IDG -2.02535 102.7 111
Iron-responsive element-binding protein 2 IREB2 Tbio Non-IDG -2.33609 211.7 253
Ferritin light chain FTL Tbio Non-IDG -2.36162 227.3 549
Natural resistance-associated macrophage protein 1 SLC11A1 Tbio Transporter -2.77524 629.3 129
Ferritin heavy polypeptide-like 17 FTHL17 Tdark Non-IDG -0.94371 8.18 33
Putative ferritin heavy polypeptide-like 19 FTH1P19 Tdark Non-IDG 0.00000 0
Ferritin, mitochondrial FTMT Tbio Non-IDG -1.11598 13.8 34
Protein tweety homolog 1 TTYH1 Tbio Ion Channel -0.94799 0.00000 131
Transferrin receptor protein 2 TFR2 Tbio Enzyme -2.11882 135.2 149
Ferritin heavy chain FTH1 Tbio Non-IDG -3.00480 982.1 562