Development Level

Tbio 20 | 11,445
Tchem 5 | 1,598
Tdark 4 | 6,588

IMPC Phenotype

increased mean corpuscular hem... 4 | 96
preweaning lethality, complete... 2 | 979
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal embryo size 1 | 220
abnormal gait 1 | 69
abnormal heart morphology 1 | 162
abnormal skin morphology 1 | 50
decreased circulating aspartat... 1 | 34
decreased circulating bilirubi... 1 | 19
decreased circulating chloride... 1 | 30
decreased circulating potassiu... 1 | 20
decreased erythrocyte cell num... 1 | 62
decreased hemoglobin content 1 | 68
decreased leukocyte cell numbe... 1 | 73
decreased monocyte cell number 1 | 8
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
enlarged spleen 1 | 41
hydrometra 1 | 53
hyperactivity 1 | 148
increased body length 1 | 32
increased circulating iron lev... 1 | 30
increased circulating potassiu... 1 | 29
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased mean corpuscular vol... 1 | 92
prenatal lethality prior to he... 1 | 87
prolonged PR interval 1 | 15
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
small superior vagus ganglion 1 | 74

Disease

Carcinoma 24 | 11,493
osteosarcoma 21 | 7,950
ovarian cancer 16 | 8,520
medulloblastoma, large-cell 14 | 6,241
psoriasis 14 | 6,694
glioblastoma 11 | 5,792
lung carcinoma 11 | 2,843
Anemia 10 | 365
atypical teratoid / rhabdoid tumor 10 | 5,112
ependymoma 10 | 4,679
lung adenocarcinoma 10 | 2,716
lung cancer 10 | 4,740
pancreatic ductal adenocarcinoma liver metastasis 10 | 1,962
group 3 medulloblastoma 9 | 4,104
invasive ductal carcinoma 9 | 2,951
tuberculosis 9 | 2,010
adult high grade glioma 8 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
malignant mesothelioma 8 | 3,232
non-small cell lung cancer 8 | 2,890
Autosomal recessive predisposition 7 | 1,442
Breast cancer 7 | 3,578
Hemochromatosis 7 | 54
cystic fibrosis 7 | 1,696
pancreatic cancer 7 | 2,398
pituitary cancer 7 | 1,972
Cancer 6 | 2,499
Thalassemia 6 | 53
diabetes mellitus 6 | 1,728
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
oligodendroglioma 6 | 2,850
subependymal giant cell astrocytoma 6 | 2,287
Aceruloplasminemia 5 | 16
Astrocytoma, Pilocytic 5 | 3,081
Liver disease 5 | 237
ductal carcinoma in situ 5 | 1,745
mucosa-associated lymphoid tissue lymphoma 5 | 484
primitive neuroectodermal tumor 5 | 3,035
ulcerative colitis 5 | 1,819
Alzheimer Disease 4 | 83
Alzheimer's disease 4 | 658
Atransferrinemia 4 | 8
Hepatomegaly 4 | 285
Hyperferritinaemia 4 | 14
Hypertension 4 | 396
Increased ferritin 4 | 14
Iron metabolism disease 4 | 20
Kidney cancer 4 | 2,613
Obesity 4 | 678
Schizophrenia 4 | 1,160
Serum ferritin increased 4 | 14
Splenomegaly 4 | 190
adrenocortical carcinoma 4 | 1,428
breast carcinoma 4 | 1,638
esophageal adenocarcinoma 4 | 737
interstitial cystitis 4 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
sonic hedgehog group medulloblastoma 4 | 467
Acute kidney injury 3 | 70
Anemia, Hemolytic 3 | 55
Arthritis 3 | 290
Arthropathy 3 | 43
Chemical and Drug Induced Liver Injury 3 | 195
Congestive heart failure 3 | 113
Heart failure 3 | 162
Hemochromatosis type 1 3 | 9
Hemolytic anemia 3 | 77
Hypogonadism 3 | 173
Iron deficiency anemia 3 | 12
Kidney disease 3 | 430
Liver Cirrhosis, Experimental 3 | 769
Lung disease 3 | 142
Multiple myeloma 3 | 1,332
Neoplasm Invasiveness 3 | 161
Neurodegenerative disease 3 | 414
Peripheral vascular disease 3 | 87
Pick disease 3 | 1,894
Prostatic Neoplasms 3 | 495
Rheumatoid arthritis 3 | 1,191
astrocytic glioma 3 | 2,597
astrocytoma 3 | 1,146
Atopic dermatitis 2 | 952
Cholestasis 2 | 155
Down syndrome 2 | 499
Heart disease 2 | 306
Hemoglobin low 2 | 124
Malaria 2 | 160
Prostate cancer 2 | 175
Schizoaffective Disorder 2 | 55
Type 2 diabetes mellitus 2 | 272
active ulcerative colitis 2 | 764
aldosterone-producing adenoma 2 | 665
hepatocellular carcinoma 2 | 547
medulloblastoma 2 | 720
nasopharyngeal carcinoma 2 | 1,058
pediatric high grade glioma 2 | 1,064
progressive supranuclear palsy 2 | 676
spina bifida 2 | 1,074
substance-related disorder 2 | 162
urothelial carcinoma 2 | 318

Tissue

Endocrine System 29 | 18,159
Liver and Pancreas 29 | 16,750
Blood and immune system 28 | 16,909
Digestive Tract 28 | 17,369
Female tissues 28 | 17,400
Male tissues 28 | 17,142
Nervous System 28 | 16,725
Skin and soft tissues 28 | 17,230
Urinary Tract 27 | 16,678
Cardiovascular System 26 | 15,192
Respiratory system 26 | 16,393

Target Family

Non-IDG 15 | 12,091
Enzyme 10 | 4,145
Transporter 3 | 473
Kinase 1 | 634

GO Process

iron ion homeostasis 29 | 29
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
3-hydroxybutyrate dehydrogenase type 2 BDH2 Tbio Enzyme -1.15003 15.8 112
Metalloreductase STEAP1 STEAP1 Tbio Enzyme -1.65454 46.2 322
Sideroflexin-4 SFXN4 Tbio Non-IDG -0.28426 2.10 77
Serotransferrin TF Tbio Non-IDG -4.15070 13447.9 1168
Ferritin light chain FTL Tbio Non-IDG -2.36162 227.3 549
Transmembrane protease serine 6 TMPRSS6 Tchem Enzyme -2.03522 125.4 122
Metalloreductase STEAP2 STEAP2 Tbio Enzyme -1.78852 56.5 154
Natural resistance-associated macrophage protein 1 SLC11A1 Tbio Transporter -2.77524 629.3 129
Mitoferrin-1 SLC25A37 Tbio Transporter -1.58954 37.6 97
Mitoferrin-2 SLC25A28 Tbio Transporter -1.06193 10.8 111