Development Level

Tbio 58 | 11,445
Tchem 21 | 1,598
Tclin 11 | 613
Tdark 9 | 6,588

Collection

Ion Channel: IDG Consortium (T... 10 | 99

IMPC Phenotype

preweaning lethality, incomple... 6 | 499
preweaning lethality, complete... 4 | 979
abnormal sleep behavior 3 | 70
increased circulating alkaline... 3 | 122
abnormal behavior 2 | 298
abnormal bone structure 2 | 187
cataract 2 | 92
decreased bone mineral content 2 | 151
decreased bone mineral density 2 | 126
decreased circulating insulin ... 2 | 76
decreased fasted circulating g... 2 | 65
decreased prepulse inhibition 2 | 82
hyperactivity 2 | 148
increased circulating creatini... 2 | 38
increased startle reflex 2 | 112
abnormal coat appearance 1 | 31
abnormal coat-hair pigmentatio... 1 | 64
abnormal cornea morphology 1 | 31
abnormal embryo size 1 | 220
abnormal epididymis morphology 1 | 42
abnormal incisor color 1 | 3
abnormal iris morphology 1 | 13
abnormal iris transilluminatio... 1 | 2
abnormal lens morphology 1 | 81
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal spine curvature 1 | 9
abnormal vocalization 1 | 21
absent pinna reflex 1 | 23
absent startle reflex 1 | 24
decreased body length 1 | 101
decreased body weight 1 | 161
decreased circulating HDL chol... 1 | 68
decreased circulating calcium ... 1 | 36
decreased circulating chloride... 1 | 30
decreased circulating glucose ... 1 | 126
decreased circulating serum al... 1 | 82
decreased exploration in new e... 1 | 11
decreased grip strength 1 | 116
decreased hemoglobin content 1 | 68
decreased mean corpuscular vol... 1 | 79
decreased red blood cell distr... 1 | 41
decreased startle reflex 1 | 75
decreased total body fat amoun... 1 | 207
decreased urine creatinine lev... 1 | 3
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
enlarged heart 1 | 210
enlarged thymus 1 | 5
eyelids fail to open 1 | 3
fusion of vertebral arches 1 | 7
impaired glucose tolerance 1 | 75
impaired righting response 1 | 26
increased blood urea nitrogen ... 1 | 48
increased body length 1 | 32
increased circulating HDL chol... 1 | 80
increased circulating amylase ... 1 | 25
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating iron lev... 1 | 30
increased circulating serum al... 1 | 22
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 42
increased grip strength 1 | 41
increased heart weight 1 | 62
kyphosis 1 | 5
limb grasping 1 | 41
polysyndactyly 1 | 2
prolonged QRS complex duration 1 | 8
vertebral transformation 1 | 12

Disease

Carcinoma 80 | 11,493
glioblastoma 44 | 5,792
osteosarcoma 43 | 7,950
atypical teratoid / rhabdoid tumor 42 | 5,112
ependymoma 41 | 4,679
medulloblastoma, large-cell 39 | 6,241
ovarian cancer 37 | 8,520
psoriasis 37 | 6,694
adult high grade glioma 29 | 3,801
group 3 medulloblastoma 28 | 4,104
Astrocytoma, Pilocytic 24 | 3,081
intraductal papillary-mucinous adenoma (IPMA) 24 | 2,955
oligodendroglioma 23 | 2,850
primitive neuroectodermal tumor 23 | 3,035
Epilepsy 22 | 792
intraductal papillary-mucinous neoplasm (IPMN) 22 | 3,291
Schizophrenia 21 | 1,160
astrocytic glioma 20 | 2,597
intraductal papillary-mucinous carcinoma (IPMC) 20 | 2,989
lung cancer 20 | 4,740
lung carcinoma 20 | 2,843
Kidney cancer 19 | 2,613
Seizures 18 | 596
malignant mesothelioma 18 | 3,232
pituitary cancer 17 | 1,972
Autosomal recessive predisposition 16 | 1,442
pancreatic cancer 16 | 2,398
Pick disease 15 | 1,894
lung adenocarcinoma 15 | 2,716
subependymal giant cell astrocytoma 15 | 2,287
Breast cancer 14 | 3,578
non-small cell lung cancer 14 | 2,890
cystic fibrosis 13 | 1,696
ulcerative colitis 13 | 1,819
astrocytoma 12 | 1,146
tuberculosis 12 | 2,010
Autistic Disorder 11 | 364
Bipolar Disorder 11 | 666
ductal carcinoma in situ 11 | 1,745
interstitial cystitis 11 | 2,312
Metabolic acidosis 10 | 90
Pendred Syndrome 10 | 22
active ulcerative colitis 10 | 764
Hypertension 9 | 396
invasive ductal carcinoma 9 | 2,951
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,962
primary pancreatic ductal adenocarcinoma 9 | 1,109
Cancer 8 | 2,499
Diarrhea 8 | 253
Diastrophic dysplasia 8 | 21
Intellectual disability 8 | 1,016
colon cancer 8 | 1,478
cutaneous lupus erythematosus 8 | 1,057
group 4 medulloblastoma 8 | 1,855
non primary Sjogren syndrome sicca 8 | 891
Alzheimer's disease 7 | 658
Edema 7 | 81
Melanoma 7 | 711
Nonsyndromic deafness 7 | 142
active Crohn's disease 7 | 922
gastric carcinoma 7 | 807
pediatric high grade glioma 7 | 1,064
Alcoholic Intoxication, Chronic 6 | 289
Cognitive delay 6 | 608
Endometriosis 6 | 540
Global developmental delay 6 | 608
Hypertensive disorder 6 | 56
Kidney disease 6 | 430
Mental and motor retardation 6 | 608
Nicotine dependence 6 | 54
Parkinson's disease 6 | 392
Skin cancer 6 | 469
esophageal adenocarcinoma 6 | 737
medulloblastoma 6 | 720
mucosa-associated lymphoid tissue lymphoma 6 | 484
nasopharyngeal carcinoma 6 | 1,058
Alcohol dependence 5 | 107
Atopic dermatitis 5 | 952
Brain Ischemia 5 | 110
Calcinosis 5 | 70
Depressive disorder 5 | 409
Dull intelligence 5 | 645
Heart disease 5 | 306
Hypertensive disease 5 | 292
Hypokalemia 5 | 52
Inflammation 5 | 120
Low intelligence 5 | 645
Mental Retardation 5 | 645
Mental deficiency 5 | 645
Muscle hypotonia 5 | 571
Poor school performance 5 | 645
Schnyder Corneal Dystrophy 5 | 23
Short stature 5 | 531
fibroadenoma 5 | 559
pancreatic carcinoma 5 | 562
progressive supranuclear palsy 5 | 676
Attention deficit hyperactivity disorder 4 | 278
acute myeloid leukemia 4 | 783
juvenile dermatomyositis 4 | 1,187
spina bifida 4 | 1,074

Tissue

Endocrine System 97 | 18,159
Female tissues 95 | 17,400
Nervous System 94 | 16,725
Urinary Tract 94 | 16,678
Liver and Pancreas 93 | 16,750
Digestive Tract 92 | 17,369
Blood and immune system 90 | 16,909
Male tissues 90 | 17,142
Skin and soft tissues 90 | 17,230
Respiratory system 87 | 16,393
Cardiovascular System 79 | 15,192

Target Family

Transporter 58 | 473
Ion Channel 23 | 344
Non-IDG 13 | 12,091
Enzyme 3 | 4,145
Kinase 2 | 634

GO Process

ion transport 99 | 99
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Solute carrier family 12 member 7 SLC12A7 Tbio Transporter -1.46102 28.2 156
Solute carrier family 12 member 1 SLC12A1 Tclin Transporter -2.37125 226.3 178
Sodium-dependent phosphate transport protein 1 SLC17A1 Tbio Transporter -1.73498 53.1 39
Sodium-independent sulfate anion transporter SLC26A11 Tdark Transporter -0.88219 7.87 8
Proton-coupled amino acid transporter 2 SLC36A2 Tchem Transporter -1.78507 61.5 88
LIM and SH3 domain protein 1 LASP1 Tbio Non-IDG -1.87137 77.5 299
Na(+)/H(+) exchange regulatory cofactor NHE-RF4 PDZD3 Tbio Non-IDG -0.76581 6.17 121
Sodium/potassium/calcium exchanger 3 SLC24A3 Tbio Transporter -1.12274 13.0 86
Sodium/potassium/calcium exchanger 2 SLC24A2 Tbio Transporter -1.39605 25.7 32
Solute carrier family 12 member 6 SLC12A6 Tbio Transporter -1.73943 58.4 161