Development Level

Tbio 16 | 11,445
Tdark 8 | 6,588

IMPC Phenotype

increased circulating alkaline... 2 | 122
increased total body fat amoun... 2 | 134
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
abnormal gait 1 | 69
abnormal heart left ventricle ... 1 | 16
abnormal retina morphology 1 | 71
abnormal tooth morphology 1 | 24
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating glucose ... 1 | 126
decreased circulating serum al... 1 | 82
decreased circulating sodium l... 1 | 22
decreased erythrocyte cell num... 1 | 62
decreased grip strength 1 | 116
decreased heart rate variabili... 1 | 13
decreased heart weight 1 | 27
decreased lean body mass 1 | 135
decreased prepulse inhibition 1 | 82
decreased respiratory quotient 1 | 16
decreased spleen weight 1 | 10
impaired glucose tolerance 1 | 75
increased circulating LDL chol... 1 | 13
increased circulating alanine ... 1 | 13
increased circulating aspartat... 1 | 15
increased circulating bilirubi... 1 | 16
increased circulating choleste... 1 | 66
increased circulating free fat... 1 | 20
increased circulating glucose ... 1 | 24
increased circulating triglyce... 1 | 42
increased fasted circulating g... 1 | 76
increased heart weight 1 | 62
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 96
increased mean corpuscular hem... 1 | 36
increased mean corpuscular vol... 1 | 92
increased prepulse inhibition 1 | 32
increased startle reflex 1 | 112
short tibia 1 | 97
thrombocytopenia 1 | 56

Disease

Carcinoma 14 | 11,493
medulloblastoma, large-cell 13 | 6,241
ovarian cancer 13 | 8,520
osteosarcoma 11 | 7,950
atypical teratoid / rhabdoid tumor 10 | 5,112
glioblastoma 10 | 5,792
oligodendroglioma 8 | 2,850
ependymoma 7 | 4,679
psoriasis 7 | 6,694
Obesity 6 | 678
astrocytic glioma 6 | 2,597
malignant mesothelioma 6 | 3,232
Astrocytoma, Pilocytic 5 | 3,081
Intellectual disability 5 | 1,016
Pick disease 5 | 1,894
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
Autosomal recessive predisposition 4 | 1,442
Bardet-Biedl syndrome 4 | 51
Bardet-Biedl syndrome 1 4 | 22
Ciliopathy 4 | 71
Cone dystrophy 4 | 71
Hypertensive disease 4 | 292
Polydactyly 4 | 107
adult high grade glioma 4 | 3,801
diabetes mellitus 4 | 1,728
group 3 medulloblastoma 4 | 4,104
group 4 medulloblastoma 4 | 1,855
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
pancreatic cancer 4 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
pituitary cancer 4 | 1,972
primitive neuroectodermal tumor 4 | 3,035
Brachydactyly 3 | 156
Cancer 3 | 2,499
Congenital hypoplasia of ovary 3 | 30
Congenital hypoplasia of penis 3 | 176
Dull intelligence 3 | 645
Electroretinogram abnormal 3 | 95
Fundus dystrophy 3 | 83
Hypogonadism 3 | 173
Hypoplastic ovary 3 | 30
Increase in blood pressure 3 | 119
Low intelligence 3 | 645
Mental Retardation 3 | 645
Mental deficiency 3 | 645
Multicystic Dysplastic Kidney 3 | 52
Nystagmus 3 | 317
Poor school performance 3 | 645
Retinitis Pigmentosa 3 | 226
Rheumatoid arthritis 3 | 1,191
Short stature 3 | 531
Small genitalia 3 | 13
Ulnar polydactyly of fingers 3 | 47
lung cancer 3 | 4,740
lung carcinoma 3 | 2,843
ulcerative colitis 3 | 1,819
Alzheimer's disease 2 | 658
Asthma 2 | 385
Bipolar Disorder 2 | 666
Breast cancer 2 | 3,578
Cognitive delay 2 | 608
Delayed speech and language development 2 | 112
Endometrial cancer 2 | 311
Global developmental delay 2 | 608
High, narrow palate 2 | 32
Inadequate arch length for tooth size 2 | 45
Kidney cancer 2 | 2,613
Kidney disease 2 | 430
Language Delay 2 | 112
Left Ventricular Hypertrophy 2 | 47
Liver cancer 2 | 604
Mental and motor retardation 2 | 608
Radially deviated fingers 2 | 38
Reactive airway disease 2 | 21
Retinal Degeneration 2 | 106
Schizophrenia 2 | 1,160
Specific learning disability 2 | 47
Speech Delay 2 | 112
Speech Disorders 2 | 58
Speech impairment 2 | 112
Strabismus 2 | 270
Tooth Crowding 2 | 45
Tooth mass arch size discrepancy 2 | 45
Tooth size discrepancy 2 | 45
acute quadriplegic myopathy 2 | 1,158
adrenocortical carcinoma 2 | 1,428
aldosterone-producing adenoma 2 | 665
chronic rhinosinusitis 2 | 512
hepatocellular carcinoma 2 | 547
interstitial cystitis 2 | 2,312
invasive ductal carcinoma 2 | 2,951
juvenile dermatomyositis 2 | 1,187
medulloblastoma 2 | 720
nasopharyngeal carcinoma 2 | 1,058
primary pancreatic ductal adenocarcinoma 2 | 1,109
progressive supranuclear palsy 2 | 676
sonic hedgehog group medulloblastoma 2 | 467
spina bifida 2 | 1,074
tuberculosis 2 | 2,010

Tissue

Blood and immune system 23 | 16,909
Digestive Tract 23 | 17,369
Endocrine System 23 | 18,159
Female tissues 23 | 17,400
Liver and Pancreas 23 | 16,750
Male tissues 23 | 17,142
Skin and soft tissues 23 | 17,230
Nervous System 22 | 16,725
Respiratory system 22 | 16,393
Urinary Tract 22 | 16,678
Cardiovascular System 20 | 15,192

Target Family

Non-IDG 22 | 12,091
Enzyme 2 | 4,145

GO Process

intracellular transport 24 | 24
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Bardet-Biedl syndrome 4 protein BBS4 Tbio Non-IDG -1.53435 31.5 200
Biogenesis of lysosome-related organelles complex 1 subunit 4 BLOC1S4 Tdark Non-IDG 0.00000 53
RANBP2-like and GRIP domain-containing protein 5/6 RGPD5 Tdark Non-IDG -0.58854 3.99 54
Ras-related protein Rab-14 RAB14 Tbio Enzyme -1.47825 30.5 103
Formin-2 FMN2 Tbio Non-IDG -1.72748 52.6 96
Diphosphoinositol polyphosphate phosphohydrolase 2 NUDT4 Tbio Enzyme -1.09922 14.5 74
Protein spire homolog 2 SPIRE2 Tbio Non-IDG -0.76971 5.22 91
Syntenin-2 SDCBP2 Tbio Non-IDG -0.83488 7.25 182
RANBP2-like and GRIP domain-containing protein 1 RGPD1 Tdark Non-IDG 0.00000 3
RANBP2-like and GRIP domain-containing protein 2 RGPD2 Tdark Non-IDG -1.20650 14.2 2