Development Level

Tbio 160 | 11,651
Tdark 38 | 6,593
Tclin 6 | 612
Tchem 5 | 1,388

Collection

Kinase: IDG Consortium (Target... 2 | 125
RFA-RM-18-021 2 | 328

IMPC Phenotype

preweaning lethality, complete... 15 | 979
decreased body weight 6 | 161
decreased total body fat amoun... 6 | 207
preweaning lethality, incomple... 6 | 499
decreased circulating HDL chol... 5 | 68
decreased circulating choleste... 5 | 93
increased mean corpuscular hem... 5 | 96
decreased circulating triglyce... 4 | 79
embryonic lethality prior to o... 4 | 239
embryonic lethality prior to t... 4 | 278
abnormal behavior 3 | 298
abnormal bone structure 3 | 187
decreased circulating LDL chol... 3 | 38
decreased circulating alkaline... 3 | 46
decreased circulating glucose ... 3 | 126
decreased circulating serum al... 3 | 82
decreased leukocyte cell numbe... 3 | 73
increased circulating free fat... 3 | 20
increased grip strength 3 | 41
increased hematocrit 3 | 46
increased lean body mass 3 | 172
increased or absent threshold ... 3 | 101
tremors 3 | 39
abnormal bone mineralization 2 | 38
abnormal embryo size 2 | 220
abnormal seminal vesicle morph... 2 | 114
absent pinna reflex 2 | 23
decreased circulating alanine ... 2 | 47
decreased circulating free fat... 2 | 31
decreased circulating fructosa... 2 | 30
decreased circulating insulin ... 2 | 76
decreased circulating lactate ... 2 | 3
decreased grip strength 2 | 116
decreased hemoglobin content 2 | 68
decreased vertical activity 2 | 208
enlarged heart 2 | 210
enlarged seminal vesicle 2 | 10
hyperactivity 2 | 148
increased blood urea nitrogen ... 2 | 48
increased circulating alkaline... 2 | 122
increased circulating aspartat... 2 | 15
increased heart weight 2 | 62
increased mean corpuscular vol... 2 | 92
increased red blood cell distr... 2 | 34
increased startle reflex 2 | 112
increased total body fat amoun... 2 | 134
prolonged PR interval 2 | 15
trunk curl 2 | 16
abnormal coat appearance 1 | 31
abnormal craniofacial morpholo... 1 | 33
abnormal gait 1 | 69
abnormal liver morphology 1 | 17
abnormal locomotor activation 1 | 16
abnormal response to new envir... 1 | 10
abnormal skin condition 1 | 6
abnormal sleep behavior 1 | 70
abnormal testis morphology 1 | 43
abnormal vertebrae morphology 1 | 18
abnormal whole-body plethysmog... 1 | 4
cardiovascular system phenotyp... 1 | 36
convulsive seizures 1 | 13
decreased IgE level 1 | 6
decreased bone mineral density 1 | 126
decreased circulating amylase ... 1 | 28
decreased circulating chloride... 1 | 30
decreased circulating creatini... 1 | 39
decreased circulating potassiu... 1 | 20
decreased circulating sodium l... 1 | 22
decreased erythrocyte cell num... 1 | 62
decreased hematocrit 1 | 46
decreased red blood cell distr... 1 | 41
edema 1 | 59
embryonic growth retardation 1 | 106
female infertility 1 | 60
hemorrhage 1 | 23
hydrometra 1 | 53
impaired glucose tolerance 1 | 75
impaired righting response 1 | 26
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating alanine ... 1 | 13
increased circulating amylase ... 1 | 25
increased circulating chloride... 1 | 41
increased circulating glucose ... 1 | 24
increased circulating phosphat... 1 | 26
increased circulating serum al... 1 | 22
increased circulating sodium l... 1 | 71
increased exploration in new e... 1 | 8
increased fasted circulating g... 1 | 76
increased heart rate 1 | 23
increased vertical activity 1 | 24
limb grasping 1 | 41
microphthalmia 1 | 26
persistence of hyaloid vascula... 1 | 33
prolonged RR interval 1 | 8
small superior vagus ganglion 1 | 74
small testis 1 | 58
small thymus 1 | 16
stereotypic behavior 1 | 3
thrombocytosis 1 | 27

Disease

Carcinoma 134 | 11,493
osteosarcoma 113 | 7,950
ovarian cancer 112 | 8,520
medulloblastoma, large-cell 72 | 6,241
glioblastoma 70 | 5,792
psoriasis 70 | 6,694
atypical teratoid / rhabdoid tumor 62 | 5,112
ependymoma 58 | 4,679
lung cancer 45 | 4,740
Breast cancer 41 | 3,578
invasive ductal carcinoma 40 | 2,951
adult high grade glioma 38 | 3,801
oligodendroglioma 38 | 2,850
astrocytic glioma 36 | 2,597
intraductal papillary-mucinous adenoma (IPMA) 36 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 36 | 3,291
malignant mesothelioma 36 | 3,232
Astrocytoma, Pilocytic 34 | 3,081
intraductal papillary-mucinous carcinoma (IPMC) 34 | 2,989
Pick disease 32 | 1,894
group 3 medulloblastoma 32 | 4,104
Kidney cancer 31 | 2,613
tuberculosis 31 | 2,010
lung carcinoma 30 | 2,843
pancreatic cancer 30 | 2,398
subependymal giant cell astrocytoma 30 | 2,287
lung adenocarcinoma 29 | 2,716
non-small cell lung cancer 29 | 2,890
group 4 medulloblastoma 26 | 1,855
pancreatic ductal adenocarcinoma liver metastasis 25 | 1,962
primitive neuroectodermal tumor 25 | 3,035
interstitial cystitis 23 | 2,312
Multiple myeloma 21 | 1,332
diabetes mellitus 20 | 1,728
Autosomal recessive predisposition 19 | 1,442
ductal carcinoma in situ 19 | 1,745
pituitary cancer 19 | 1,972
acute quadriplegic myopathy 16 | 1,158
primary pancreatic ductal adenocarcinoma 16 | 1,109
Cancer 15 | 2,499
adrenocortical carcinoma 15 | 1,428
astrocytoma 15 | 1,146
breast carcinoma 15 | 1,638
Intellectual disability 14 | 1,016
colon cancer 14 | 1,478
cystic fibrosis 14 | 1,696
spina bifida 14 | 1,074
dermatomyositis 13 | 966
Cognitive delay 12 | 608
Global developmental delay 12 | 608
Mental and motor retardation 12 | 608
Rheumatoid arthritis 12 | 1,191
Schizophrenia 12 | 1,160
active Crohn's disease 12 | 922
pediatric high grade glioma 12 | 1,064
ulcerative colitis 12 | 1,819
Dull intelligence 11 | 645
Low intelligence 11 | 645
Mental Retardation 11 | 645
Mental deficiency 11 | 645
Poor school performance 11 | 645
active ulcerative colitis 11 | 764
medulloblastoma 11 | 720
pancreatic carcinoma 11 | 562
Alzheimer's disease 10 | 658
juvenile dermatomyositis 10 | 1,187
Liver Cirrhosis, Experimental 9 | 769
gastric carcinoma 9 | 807
mucosa-associated lymphoid tissue lymphoma 9 | 484
progressive supranuclear palsy 9 | 676
sonic hedgehog group medulloblastoma 9 | 467
Cataract 8 multiple types 8 | 33
Short stature 8 | 531
Bipolar Disorder 7 | 666
Down syndrome 7 | 499
Duchenne muscular dystrophy 7 | 601
Muscle hypotonia 7 | 571
Prostatic Neoplasms 7 | 495
Type 2 diabetes mellitus 7 | 272
Waldenstrons macroglobulinemia 7 | 765
acute myeloid leukemia 7 | 783
nasopharyngeal carcinoma 7 | 1,058
non primary Sjogren syndrome sicca 7 | 891
tuberculosis and treatment for 3 months 7 | 179
ARC syndrome 6 | 13
Amyotrophic lateral sclerosis 6 | 451
Gaucher disease type 1 6 | 180
Griscelli syndrome 6 | 24
Hermansky-Pudlak syndrome 6 | 42
Hypomyelinating leukodystrophy 6 6 | 26
Melanoma 6 | 711
Menkes disease 6 | 19
Small head 6 | 374
esophageal adenocarcinoma 6 | 737
fibroadenoma 6 | 559
primary Sjogren syndrome 6 | 735
Curvature of spine 5 | 282
Epilepsy 5 | 792
Polycystic ovary syndrome 5 | 360
Strabismus 5 | 270

Tissue

Endocrine System 209 | 18,159
Blood and immune system 204 | 16,909
Digestive Tract 203 | 17,369
Male tissues 203 | 17,142
Skin and soft tissues 203 | 17,230
Urinary Tract 203 | 16,678
Female tissues 202 | 17,400
Liver and Pancreas 202 | 16,750
Respiratory system 202 | 16,393
Nervous System 199 | 16,725
Cardiovascular System 197 | 15,192

Target Family

Non-IDG 187 | 12,091
Enzyme 15 | 4,145
Kinase 3 | 634
Epigenetic 2 | 242
Ion Channel 2 | 344

GO Process

intracellular protein transpor... 209 | 209
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
GTP-binding protein SAR1b SAR1B Tbio Enzyme -1.91051 79.7 184
Protein wntless homolog WLS Tbio Non-IDG -2.50699 316.3 71
Coatomer subunit beta COPB1 Tbio Non-IDG -1.94049 82.6 148
Coatomer subunit alpha COPA Tbio Non-IDG -2.45140 283.3 88
AP-3 complex subunit mu-2 AP3M2 Tbio Non-IDG -0.66901 4.79 56
Syntaxin-12 STX12 Tbio Non-IDG -1.09934 11.4 124
Melanophilin MLPH Tbio Non-IDG -1.57425 39.8 142
Sorting nexin-9 SNX9 Tbio Non-IDG -2.00279 102.8 241
Sorting nexin-8 SNX8 Tbio Non-IDG -1.38931 25.5 152
Coatomer subunit gamma-1 COPG1 Tbio Non-IDG -1.70829 49.0 89