Development Level

Tbio 15 | 11,445
Tchem 3 | 1,598
Tclin 3 | 613

IMPC Phenotype

preweaning lethality, incomple... 3 | 499
decreased neutrophil cell numb... 2 | 42
decreased vertical activity 2 | 208
enlarged heart 2 | 210
preweaning lethality, complete... 2 | 979
abnormal behavior 1 | 298
abnormal embryo size 1 | 220
abnormal femur morphology 1 | 14
abnormal heart morphology 1 | 162
abnormal retina morphology 1 | 71
decreased bone mineral content 1 | 151
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased eosinophil cell numb... 1 | 24
decreased heart left ventricle... 1 | 28
decreased lean body mass 1 | 135
decreased total body fat amoun... 1 | 207
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
increased circulating alkaline... 1 | 122
increased circulating serum al... 1 | 22
increased circulating total pr... 1 | 28
increased hemoglobin content 1 | 45
increased total body fat amoun... 1 | 134
thin ventricular wall 1 | 24

Disease

Carcinoma 16 | 11,493
ovarian cancer 13 | 8,520
psoriasis 10 | 6,694
osteosarcoma 9 | 7,950
Cancer 6 | 2,499
Kidney cancer 6 | 2,613
atypical teratoid / rhabdoid tumor 6 | 5,112
ependymoma 6 | 4,679
glioblastoma 6 | 5,792
Endometriosis 5 | 540
astrocytic glioma 5 | 2,597
group 3 medulloblastoma 5 | 4,104
group 4 medulloblastoma 5 | 1,855
lung cancer 5 | 4,740
medulloblastoma, large-cell 5 | 6,241
Bladder Neoplasm 4 | 112
Breast Neoplasms 4 | 445
Breast cancer 4 | 3,578
Mammary Neoplasms 4 | 425
Urinary Bladder Neoplasms 4 | 114
primitive neuroectodermal tumor 4 | 3,035
subependymal giant cell astrocytoma 4 | 2,287
Adenocarcinoma 3 | 122
Colorectal Neoplasms 3 | 243
Endometrial Neoplasms 3 | 55
Obesity 3 | 678
Osteoporosis 3 | 363
Rheumatoid arthritis 3 | 1,191
Schizophrenia 3 | 1,160
Vascular disease 3 | 319
astrocytoma 3 | 1,146
diabetes mellitus 3 | 1,728
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
oligodendroglioma 3 | 2,850
pancreatic cancer 3 | 2,398
tuberculosis 3 | 2,010
Acquired metabolic disease 2 | 336
Adenoid Cystic Carcinoma 2 | 99
Alzheimer's disease 2 | 658
Animal Mammary Neoplasms 2 | 136
Atrophic vaginitis 2 | 14
COPD 2 | 118
Carcinoma, Adenoid Cystic 2 | 99
Carcinoma, Hepatocellular 2 | 228
Carcinoma, Transitional Cell 2 | 32
Coronary artery disease 2 | 268
Dyspareunia 2 | 12
Endometrial cancer 2 | 311
Female hypogonadism syndrome 2 | 25
Female infertility 2 | 30
Heart disease 2 | 306
Infertility 2 | 188
Infertility, Female 2 | 28
Liver carcinoma 2 | 240
Liver neoplasms 2 | 130
Male infertility 2 | 206
Mammary Neoplasms, Animal 2 | 136
Mammary Neoplasms, Experimental 2 | 154
Melanoma 2 | 711
Menopausal flushing 2 | 17
Mental Depression 2 | 333
Metastatic Breast Cancer Progression Post-Antiestrogen Therapy 2 | 4
Multiple myeloma 2 | 1,332
Neoplasm Invasiveness 2 | 161
Neuroblastoma 2 | 80
Postmenopausal osteoporosis 2 | 19
Prevention of Breast Carcinoma 2 | 5
Prostatic Intraepithelial Neoplasia 2 | 11
Prostatic Intraepithelial Neoplasias 2 | 11
Prostatic Neoplasms 2 | 495
Stomach Neoplasms 2 | 300
Waldenstrons macroglobulinemia 2 | 765
West Nile fever 2 | 7
adult high grade glioma 2 | 3,801
breast carcinoma 2 | 1,638
colon cancer 2 | 1,478
cystic fibrosis 2 | 1,696
dermatomyositis 2 | 966
interstitial cystitis 2 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
invasive ductal carcinoma 2 | 2,951
malignant mesothelioma 2 | 3,232
non primary Sjogren syndrome sicca 2 | 891
non-small cell lung cancer 2 | 2,890
pediatric high grade glioma 2 | 1,064
pituitary cancer 2 | 1,972
spina bifida 2 | 1,074
Acanthosis Nigricans 1 | 27
Carcinosarcoma 1 | 7
Colorectal cancer 1 | 25
Coronary Arteriosclerosis 1 | 6
Feminization 1 | 1
Fibroid Tumor 1 | 6
Glomerulonephritis 1 | 46
Leiomyosarcoma 1 | 24
Lymphangioleiomyomatosis 1 | 16
Marijuana Abuse 1 | 31
Metabolic Bone Disorder 1 | 11
Neoplastic Cell Transformation 1 | 89
Retinoblastoma 1 | 19

Tissue

Endocrine System 21 | 18,159
Blood and immune system 20 | 16,909
Cardiovascular System 20 | 15,192
Digestive Tract 20 | 17,369
Female tissues 20 | 17,400
Liver and Pancreas 20 | 16,750
Male tissues 20 | 17,142
Respiratory system 20 | 16,393
Skin and soft tissues 20 | 17,230
Urinary Tract 20 | 16,678
Nervous System 18 | 16,725

Target Family

Non-IDG 11 | 12,091
Enzyme 4 | 4,145
Nuclear Receptor 2 | 48
Transcription Factor 2 | 1,400
Epigenetic 1 | 242
Kinase 1 | 634

GO Process

intracellular estrogen recepto... 21 | 21
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Probable ATP-dependent RNA helicase DDX5 DDX5 Tbio Enzyme -2.08566 121.1 344
Histone-arginine methyltransferase CARM1 CARM1 Tchem Epigenetic -2.04034 130.8 476
RNA-binding protein 14 RBM14 Tbio Non-IDG -2.10043 124.7 168
POU domain, class 4, transcription factor 2 POU4F2 Tbio Transcription Factor -1.94397 90.2 145
Transcription initiation factor TFIID subunit 7 TAF7 Tbio Non-IDG -1.16026 13.4 138
Scaffold attachment factor B1 SAFB Tbio Non-IDG -1.57498 46.4 216
Estrogen receptor beta ESR2 Tclin Nuclear Receptor -3.57388 3765.2 1096
AT-rich interactive domain-containing protein 1A ARID1A Tbio Transcription Factor -2.61778 423.3 132
Egl nine homolog 2 EGLN2 Tchem Non-IDG -2.03430 0.00000 318
Protein-arginine deiminase type-2 PADI2 Tchem Enzyme -2.21849 164.2 156