Development Level

Tbio 12 | 11,445
Tdark 2 | 6,588
Tchem 1 | 1,598

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

abnormal blood vessel morpholo... 1 | 5
abnormal chorioallantoic fusio... 1 | 8
abnormal embryo development 1 | 7
abnormal embryo size 1 | 220
abnormal embryo turning 1 | 31
abnormal forebrain development 1 | 20
abnormal heart morphology 1 | 162
abnormal hindbrain development 1 | 16
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal pharyngeal arch morph... 1 | 8
abnormal somite shape 1 | 5
abnormal spleen morphology 1 | 55
abnormal visceral yolk sac mor... 1 | 6
abnormal vitelline vasculature... 1 | 6
decreased circulating glucose ... 1 | 126
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
increased hemoglobin content 1 | 45
pale yolk sac 1 | 25
pallor 1 | 34
preweaning lethality, complete... 1 | 979

Disease

osteosarcoma 10 | 7,950
ovarian cancer 9 | 8,520
Carcinoma 8 | 11,493
Breast cancer 5 | 3,578
Cancer 5 | 2,499
atypical teratoid / rhabdoid tumor 5 | 5,112
group 3 medulloblastoma 5 | 4,104
ependymoma 4 | 4,679
glioblastoma 4 | 5,792
malignant mesothelioma 4 | 3,232
medulloblastoma, large-cell 4 | 6,241
Autosomal recessive predisposition 3 | 1,442
Xeroderma pigmentosum group F 3 | 22
lung cancer 3 | 4,740
nasopharyngeal carcinoma 3 | 1,058
Basal cell carcinoma 2 | 54
Basal cell nevi 2 | 23
Bloom syndrome 2 | 29
Disease Progression 2 | 136
Fanconi anemia 2 | 56
Fatigue 2 | 182
Hyperpigmented macules 2 | 42
Nijmegen breakage syndrome 2 | 24
Seckel syndrome 2 | 34
Spider Veins 2 | 17
Telangiectasis 2 | 36
Xeroderma pigmentosum 2 | 43
breast carcinoma 2 | 1,638
colon cancer 2 | 1,478
invasive ductal carcinoma 2 | 2,951
lung adenocarcinoma 2 | 2,716
non primary Sjogren syndrome sicca 2 | 891
non-small cell lung cancer 2 | 2,890
pituitary cancer 2 | 1,972
psoriasis 2 | 6,694
Abnormal visual pursuit 1 | 14
Adenocarcinoma of lung (disorder) 1 | 60
Amino Acid Metabolism, Inborn Errors 1 | 13
Ataxia telangiectasia 1 | 34
Atrophic condition of skin 1 | 25
Birthmark 1 | 35
Cafe au lait spots, multiple 1 | 17
Cafe-au-Lait Spots 1 | 37
Carcinoma, Non-Small-Cell Lung 1 | 107
Carcinoma, Squamous Cell 1 | 110
Childhood onset 1 | 38
Chromosome Aberrations 1 | 16
Colon diverticulum anatomic structure 1 | 15
Colorectal cancer 1 | 25
Conjunctival telangiectasis 1 | 14
Conjunctivitis 1 | 53
Conjunctivitis, recurrent 1 | 37
Death in early adulthood 1 | 24
Dental abnormalities 1 | 60
Diverticular disease of colon 1 | 15
Dry skin 1 | 75
Dysdiadochokinesis 1 | 25
Ectropion 1 | 38
Entropion 1 | 22
Erythema 1 | 58
Familial adenomatous polyposis 1 | 32
Fibrous skin tumor of tuberous sclerosis 1 | 18
Flushing 1 | 60
Freckles 1 | 33
Frequent falls 1 | 12
Gastrointestinal Hemorrhage 1 | 52
Glioma 1 | 74
Glioma Susceptibility 1 1 | 5
Hematologic Neoplasms 1 | 22
Hereditary Breast and Ovarian Cancer Syndrome 1 | 14
Hereditary Nonpolyposis Colorectal Neoplasms 1 | 8
Hyperkeratosis 1 | 50
Impaired smooth pursuit 1 | 14
Increased gastric cancer 1 | 21
Intermittent migraine headaches 1 | 68
Irritation - emotion 1 | 68
Lynch syndrome 1 | 35
Malignant tumor of colon 1 | 19
Micronuclei, Chromosome-Defective 1 | 25
Multiple cranial nerve palsy 1 | 3
Neoplasms 1 | 63
Neoplasms, Second Primary 1 | 6
Nystagmus, End-Position 1 | 12
Oral squamous cell carcinoma 1 | 11
Ovarian Neoplasms 1 | 102
Papilloma 1 | 44
Photosensitivity of skin 1 | 51
Poikiloderma 1 | 14
Progressive mental retardation 1 | 37
Rectal Neoplasms 1 | 18
Rhabdomyosarcoma 1 | 39
Schimke immuno-osseous dysplasia 1 | 8
Sebaceous adenoma 1 | 26
Squamous cell carcinoma of skin 1 | 11
Telangiectasia of the skin 1 | 39
Tooth Abnormalities 1 | 69
Xeroderma pigmentosum group G 1 | 16
Xerosis 1 | 75
hypopigmented skin patch 1 | 59
ovarian neoplasm 1 | 99

Tissue

Blood and immune system 15 | 16,909
Digestive Tract 15 | 17,369
Endocrine System 15 | 18,159
Female tissues 15 | 17,400
Male tissues 15 | 17,142
Respiratory system 15 | 16,393
Skin and soft tissues 15 | 17,230
Liver and Pancreas 14 | 16,750
Nervous System 14 | 16,725
Urinary Tract 14 | 16,678
Cardiovascular System 13 | 15,192

Target Family

Non-IDG 10 | 12,091
Enzyme 3 | 4,145
Kinase 1 | 634
Transcription Factor 1 | 1,400

GO Process

intra-S DNA damage checkpoint 15 | 15
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Oral cancer-overexpressed protein 1 ORAOV1 Tbio Non-IDG -1.06859 14.3 41
Crossover junction endonuclease MUS81 MUS81 Tbio Enzyme -2.06893 119.1 95
Cell cycle checkpoint control protein RAD9A RAD9A Tbio Non-IDG -2.15330 141.0 919
Cyclic AMP-dependent transcription factor ATF-2 ATF2 Tbio Transcription Factor -2.23104 170.7 1819
Cell cycle checkpoint control protein RAD9B RAD9B Tdark Non-IDG -0.07767 1.44 35
TIMELESS-interacting protein TIPIN Tbio Non-IDG -1.44126 28.4 246
DNA repair protein complementing XP-C cells XPC Tbio Non-IDG -2.21142 154.0 208
Serine/threonine-protein kinase Nek11 NEK11 Tchem Kinase -0.69544 5.52 155
Double-strand break repair protein MRE11 MRE11 Tbio Non-IDG -2.02762 98.5 459
Probable crossover junction endonuclease EME2 EME2 Tbio Enzyme -1.58584 32.6 69