Development Level

Tbio 41 | 11,445
Tchem 5 | 1,598
Tdark 2 | 6,588

IMPC Phenotype

preweaning lethality, complete... 4 | 979
embryonic lethality prior to o... 3 | 239
embryonic lethality prior to t... 3 | 278
anophthalmia 2 | 33
corneal opacity 2 | 32
decreased circulating glucose ... 2 | 126
preweaning lethality, incomple... 2 | 499
abnormal blood vessel morpholo... 1 | 5
abnormal bone structure 1 | 187
abnormal coat-hair pigmentatio... 1 | 64
abnormal cornea morphology 1 | 31
abnormal cranium morphology 1 | 36
abnormal eye morphology 1 | 68
abnormal eye size 1 | 7
abnormal iris transilluminatio... 1 | 2
abnormal lens morphology 1 | 81
abnormal placement of pupils 1 | 6
abnormal spinal cord morpholog... 1 | 9
abnormal spleen morphology 1 | 55
abnormal vitreous body morphol... 1 | 10
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
cornea ulcer 1 | 1
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased fasted circulating g... 1 | 65
decreased heart rate variabili... 1 | 13
fused cornea and lens 1 | 5
increased bone mineral density 1 | 72
increased circulating sodium l... 1 | 71
increased heart weight 1 | 62
increased hemoglobin content 1 | 45
increased mean corpuscular vol... 1 | 92
iris synechia 1 | 3
narrow eye opening 1 | 12

Disease

Carcinoma 30 | 11,493
Fanconi anemia 29 | 56
ovarian cancer 27 | 8,520
osteosarcoma 24 | 7,950
group 3 medulloblastoma 20 | 4,104
medulloblastoma, large-cell 19 | 6,241
lung cancer 17 | 4,740
Anemia 16 | 365
Breast cancer 16 | 3,578
Cancer 15 | 2,499
psoriasis 15 | 6,694
Short stature 14 | 531
Small head 14 | 374
glioblastoma 14 | 5,792
Acquired scoliosis 13 | 281
Cognitive delay 13 | 608
Curvature of spine 13 | 282
Dull intelligence 13 | 645
Global developmental delay 13 | 608
Intellectual disability 13 | 1,016
Low intelligence 13 | 645
Mental Retardation 13 | 645
Mental and motor retardation 13 | 608
Mental deficiency 13 | 645
Poor school performance 13 | 645
atypical teratoid / rhabdoid tumor 13 | 5,112
primitive neuroectodermal tumor 13 | 3,035
Almond-shaped eyes 12 | 23
Chromosome Breakage 12 | 36
Decreased platelet count 12 | 111
Esophageal atresia with or without tracheoesophageal fistula 12 | 21
Increased chromosomal breakage 12 | 27
Irregular hyperpigmentation 12 | 33
Leukopenia 12 | 72
Pyridoxine-responsive sideroblastic anemia 12 | 17
Radial aplasia/hypoplasia 12 | 29
Short palpebral fissure 12 | 38
Thrombocytopenia 12 | 197
esophageal atresia/tracheoesophageal fistula 12 | 22
hypopigmented skin patch 12 | 59
malignant mesothelioma 12 | 3,232
Autosomal recessive predisposition 10 | 1,442
Esophageal atresia 10 | 43
Tracheoesophageal Fistula 10 | 36
Xeroderma pigmentosum group F 10 | 22
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,291
Bloom syndrome 8 | 29
Hemoglobin low 8 | 124
adult high grade glioma 8 | 3,801
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
invasive ductal carcinoma 8 | 2,951
pancreatic cancer 8 | 2,398
Fanconi Anemia, Complementation Group a 7 | 9
ependymoma 7 | 4,679
non-small cell lung cancer 7 | 2,890
Cryptorchidism 6 | 296
Kidney cancer 6 | 2,613
Pancytopenia 6 | 45
Strabismus 6 | 270
Thumb aplasia 6 | 16
Xeroderma pigmentosum 6 | 43
adrenocortical carcinoma 6 | 1,428
lung adenocarcinoma 6 | 2,716
Abnormally small eyeball 5 | 97
Absence of radius and ulna 5 | 15
Absent radius 5 | 15
Birthmark 5 | 35
Cafe-au-Lait Spots 5 | 37
Congenital absence of kidney 5 | 31
Congenital deafness 5 | 185
Deafness 5 | 198
Decreased size of eyeball 5 | 97
Hearing Loss, Partial 5 | 185
Hematologic Neoplasms 5 | 22
Hypoplasia of thumb 5 | 26
Leukemia 5 | 104
Microphthalmos 5 | 100
Neutrophil count decreased 5 | 47
Radial aplasia 5 | 15
ductal carcinoma in situ 5 | 1,745
hearing impairment 5 | 199
nasopharyngeal carcinoma 5 | 1,058
Allergic hypersensitivity disease 4 | 126
Congenital Heart Defects 4 | 58
Congenital heart disease 4 | 93
Ecchymosis 4 | 66
Endometriosis 4 | 540
Epilepsy 4 | 792
Horseshoe Kidney 4 | 16
Increased tendency to bruise 4 | 66
Low Birth Weights 4 | 69
Melanoma 4 | 711
Pick disease 4 | 1,894
Seizures 4 | 596
Small for gestational age (disorder) 4 | 69
Waldenstrons macroglobulinemia 4 | 765
astrocytic glioma 4 | 2,597
breast carcinoma 4 | 1,638
dermatomyositis 4 | 966
pancreatic carcinoma 4 | 562

Tissue

Blood and immune system 48 | 16,909
Digestive Tract 48 | 17,369
Endocrine System 48 | 18,159
Female tissues 48 | 17,400
Liver and Pancreas 48 | 16,750
Male tissues 48 | 17,142
Nervous System 48 | 16,725
Respiratory system 48 | 16,393
Skin and soft tissues 48 | 17,230
Urinary Tract 48 | 16,678
Cardiovascular System 46 | 15,192

Target Family

Non-IDG 31 | 12,091
Enzyme 15 | 4,145
Kinase 1 | 634
Transcription Factor 1 | 1,400

GO Process

interstrand cross-link repair 48 | 48
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
E3 ubiquitin-protein ligase FANCL FANCL Tbio Enzyme -2.46302 286.2 146
Fanconi-associated nuclease 1 FAN1 Tbio Enzyme -2.06970 115.9 85
Zinc finger and BTB domain-containing protein 32 ZBTB32 Tbio Transcription Factor -2.17117 142.7 132
Serine/threonine-protein kinase ATR ATR Tchem Kinase -2.80362 549.6 376
E3 ubiquitin-protein ligase RNF8 RNF8 Tbio Enzyme -1.80196 70.0 250
DNA repair protein XRCC3 XRCC3 Tbio Non-IDG -2.50791 314.0 414
Polyubiquitin-B UBB Tbio Non-IDG -1.98860 97.4 427
Polyubiquitin-C UBC Tbio Non-IDG -2.90157 61.9 143
Fanconi anemia group C protein FANCC Tbio Non-IDG -2.85516 703.4 348
Fanconi anemia group B protein FANCB Tbio Non-IDG -2.33079 210.0 96