Development Level

Tbio 14 | 11,445
Tchem 8 | 1,598
Tclin 6 | 613

IMPC Phenotype

decreased body weight 2 | 161
decreased circulating creatini... 2 | 39
preweaning lethality, complete... 2 | 979
abnormal seminal vesicle morph... 1 | 114
abnormal skin morphology 1 | 50
abnormal spleen morphology 1 | 55
decreased circulating aspartat... 1 | 34
decreased grip strength 1 | 116
female infertility 1 | 60
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 96
male infertility 1 | 123
preweaning lethality, incomple... 1 | 499
small testis 1 | 58

Disease

Cancer 21 | 2,499
Carcinoma 21 | 11,493
osteosarcoma 18 | 7,950
ovarian cancer 16 | 8,520
lung cancer 15 | 4,740
medulloblastoma, large-cell 15 | 6,241
psoriasis 15 | 6,694
Breast cancer 14 | 3,578
atypical teratoid / rhabdoid tumor 14 | 5,112
invasive ductal carcinoma 14 | 2,951
glioblastoma 12 | 5,792
adult high grade glioma 11 | 3,801
ductal carcinoma in situ 11 | 1,745
malignant mesothelioma 11 | 3,232
Kidney cancer 9 | 2,613
lung adenocarcinoma 9 | 2,716
Atopic dermatitis 8 | 952
breast carcinoma 8 | 1,638
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
pancreatic cancer 8 | 2,398
pituitary cancer 8 | 1,972
tuberculosis 8 | 2,010
Rheumatoid arthritis 7 | 1,191
astrocytoma 7 | 1,146
group 3 medulloblastoma 7 | 4,104
interstitial cystitis 7 | 2,312
lung carcinoma 7 | 2,843
primitive neuroectodermal tumor 7 | 3,035
Astrocytoma, Pilocytic 6 | 3,081
Failure to gain weight 6 | 365
Pediatric failure to thrive 6 | 365
Schizophrenia 6 | 1,160
Severe combined immunodeficiency 6 | 51
cutaneous lupus erythematosus 6 | 1,057
cystic fibrosis 6 | 1,696
diabetes mellitus 6 | 1,728
ependymoma 6 | 4,679
group 4 medulloblastoma 6 | 1,855
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
non-small cell lung cancer 6 | 2,890
ulcerative colitis 6 | 1,819
Autosomal recessive predisposition 5 | 1,442
Immune system cancer 5 | 140
Liver Cirrhosis, Experimental 5 | 769
Lymphoid leukemia 5 | 160
Multiple Sclerosis 5 | 540
colon cancer 5 | 1,478
dermatomyositis 5 | 966
oligodendroglioma 5 | 2,850
Anemia 4 | 365
Diarrhea 4 | 253
Fever 4 | 138
Frontal bossing 4 | 157
Hypersensitivity reaction type II disease 4 | 253
Liver cancer 4 | 604
Lymphopenia 4 | 67
Multiple myeloma 4 | 1,332
Pneumonia 4 | 174
Polycythemia vera 4 | 27
Precancerous Conditions 4 | 80
Recurrent respiratory infections 4 | 141
Stomach Neoplasms 4 | 300
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
juvenile dermatomyositis 4 | 1,187
pancreatic carcinoma 4 | 562
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
Acquired scoliosis 3 | 281
Alcoholic Intoxication, Chronic 3 | 289
Animal Mammary Neoplasms 3 | 136
Asthma 3 | 385
Bipolar Disorder 3 | 666
Breast Neoplasms 3 | 445
Broad flat nasal bridge 3 | 236
Carcinoma, Hepatocellular 3 | 228
Concave bridge of nose 3 | 195
Curvature of spine 3 | 282
Depressed nasal bridge 3 | 195
Depressed nasal root/bridge 3 | 195
Dermatitis, Allergic Contact 3 | 67
Down syndrome 3 | 499
Epilepsy 3 | 792
Infantile onset 3 | 238
Inflammatory bowel disease 3 | 151
Joint hyperflexibility 3 | 78
Liver carcinoma 3 | 240
Mammary Neoplasms 3 | 425
Nasal bridge wide 3 | 236
Pick disease 3 | 1,894
Prostatic Neoplasms 3 | 495
Pruritus 3 | 58
Seizures 3 | 596
Waldenstrons macroglobulinemia 3 | 765
active Crohn's disease 3 | 922
adrenocortical carcinoma 3 | 1,428
hepatocellular carcinoma 3 | 547
medulloblastoma 3 | 720
primary Sjogren syndrome 3 | 735
sarcoidosis 3 | 370
spina bifida 3 | 1,074
subependymal giant cell astrocytoma 3 | 2,287

Tissue

Blood and immune system 28 | 16,909
Digestive Tract 28 | 17,369
Endocrine System 28 | 18,159
Female tissues 28 | 17,400
Liver and Pancreas 28 | 16,750
Male tissues 28 | 17,142
Respiratory system 28 | 16,393
Skin and soft tissues 28 | 17,230
Urinary Tract 28 | 16,678
Cardiovascular System 27 | 15,192
Nervous System 27 | 16,725

Target Family

Non-IDG 13 | 12,091
Kinase 9 | 634
Transcription Factor 3 | 1,400
Epigenetic 2 | 242
Enzyme 1 | 4,145

GO Process

interleukin-7-mediated signali... 28 | 28
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cytokine receptor-like factor 2 CRLF2 Tbio Non-IDG -1.91113 78.7 393
Thymic stromal lymphopoietin TSLP Tbio Non-IDG -2.78236 713.0 495
Bromodomain and WD repeat-containing protein 1 BRWD1 Tbio Epigenetic -0.60507 4.36 62
Insulin receptor substrate 2 IRS2 Tbio Non-IDG -2.64133 414.7 227
Tyrosine-protein kinase JAK3 JAK3 Tclin Kinase -2.64385 453.7 292
Phosphatidylinositol 3-kinase catalytic subunit type 3 PIK3C3 Tchem Kinase -2.33238 204.8 739
Interleukin-7 receptor subunit alpha IL7R Tbio Non-IDG -2.77688 547.0 828
Suppressor of cytokine signaling 1 SOCS1 Tbio Non-IDG -3.05851 1163.8 469
Signal transducer and activator of transcription 5B STAT5B Tchem Transcription Factor -3.02570 950.5 620
Phosphatidylinositol 3-kinase regulatory subunit alpha PIK3R1 Tchem Kinase -2.51919 316.4 758