Development Level

Tbio 58 | 11,445
Tchem 17 | 1,598
Tclin 10 | 613

IMPC Phenotype

preweaning lethality, complete... 7 | 979
preweaning lethality, incomple... 4 | 499
abnormal embryo size 3 | 220
abnormal behavior 2 | 298
decreased circulating serum al... 2 | 82
decreased mean corpuscular vol... 2 | 79
embryonic lethality prior to o... 2 | 239
hemorrhage 2 | 23
increased circulating triglyce... 2 | 42
abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
abnormal coat-hair pigmentatio... 1 | 64
abnormal cranium morphology 1 | 36
abnormal femur morphology 1 | 14
abnormal locomotor behavior 1 | 24
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
decreased circulating glucose ... 1 | 126
decreased circulating sodium l... 1 | 22
decreased fasted circulating g... 1 | 65
decreased large unstained cell... 1 | 11
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 50
decreased neutrophil cell numb... 1 | 42
decreased spleen weight 1 | 10
edema 1 | 59
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
enlarged kidney 1 | 14
hyperactivity 1 | 148
impaired glucose tolerance 1 | 75
improved glucose tolerance 1 | 79
increased circulating alkaline... 1 | 122
increased circulating sodium l... 1 | 71
increased fasted circulating g... 1 | 76
increased heart weight 1 | 62
increased hematocrit 1 | 46
increased leukocyte cell numbe... 1 | 47
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased spleen weight 1 | 10
increased total body fat amoun... 1 | 134
short tibia 1 | 97
tremors 1 | 39
unresponsive to tactile stimul... 1 | 8

Disease

Carcinoma 71 | 11,493
osteosarcoma 59 | 7,950
ovarian cancer 47 | 8,520
Cancer 45 | 2,499
glioblastoma 44 | 5,792
medulloblastoma, large-cell 35 | 6,241
lung carcinoma 32 | 2,843
non-small cell lung cancer 32 | 2,890
lung cancer 31 | 4,740
ependymoma 29 | 4,679
pancreatic cancer 29 | 2,398
Astrocytoma, Pilocytic 28 | 3,081
Breast cancer 28 | 3,578
atypical teratoid / rhabdoid tumor 28 | 5,112
intraductal papillary-mucinous adenoma (IPMA) 28 | 2,955
malignant mesothelioma 28 | 3,232
psoriasis 28 | 6,694
intraductal papillary-mucinous carcinoma (IPMC) 27 | 2,989
invasive ductal carcinoma 27 | 2,951
Kidney cancer 25 | 2,613
interstitial cystitis 25 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 25 | 3,291
adult high grade glioma 24 | 3,801
lung adenocarcinoma 22 | 2,716
tuberculosis 22 | 2,010
subependymal giant cell astrocytoma 19 | 2,287
ulcerative colitis 19 | 1,819
group 3 medulloblastoma 18 | 4,104
cystic fibrosis 17 | 1,696
Liver Cirrhosis, Experimental 16 | 769
astrocytoma 16 | 1,146
cutaneous lupus erythematosus 16 | 1,057
group 4 medulloblastoma 16 | 1,855
primary pancreatic ductal adenocarcinoma 16 | 1,109
oligodendroglioma 15 | 2,850
Autosomal recessive predisposition 14 | 1,442
diabetes mellitus 14 | 1,728
gastric carcinoma 14 | 807
pancreatic ductal adenocarcinoma liver metastasis 14 | 1,962
Pick disease 13 | 1,894
primitive neuroectodermal tumor 13 | 3,035
colon cancer 12 | 1,478
Duchenne muscular dystrophy 11 | 601
astrocytic glioma 11 | 2,597
breast carcinoma 11 | 1,638
dermatomyositis 11 | 966
Down syndrome 10 | 499
Kidney disease 10 | 430
Schizophrenia 10 | 1,160
adrenocortical carcinoma 10 | 1,428
Arthritis 9 | 290
Multiple Sclerosis 9 | 540
ductal carcinoma in situ 9 | 1,745
mucosa-associated lymphoid tissue lymphoma 9 | 484
pituitary cancer 9 | 1,972
Gliosis 8 | 56
Leukocyte adhesion deficiency 8 | 16
Multiple myeloma 8 | 1,332
Neoplasm Invasiveness 8 | 161
Rheumatoid arthritis 8 | 1,191
acute myeloid leukemia 8 | 783
esophageal adenocarcinoma 8 | 737
juvenile dermatomyositis 8 | 1,187
medulloblastoma 8 | 720
pediatric high grade glioma 8 | 1,064
Cerebrovascular disease 7 | 238
Endometriosis 7 | 540
Hypertension 7 | 396
Hypertensive disease 7 | 292
head and neck cancer 7 | 271
head and neck cancer and chronic obstructive pulmonary disease 7 | 239
hereditary spastic paraplegia 7 | 318
nasopharyngeal carcinoma 7 | 1,058
Adenocarcinoma 6 | 122
Anemia 6 | 365
Atopic dermatitis 6 | 952
Blastic phase chronic myeloid leukemia 6 | 58
Chronic Myelocytic Leukemia Accelerated Phase 6 | 59
Liver cancer 6 | 604
Liver diseases 6 | 87
Melanoma 6 | 711
Thrombocytopenia 6 | 197
Vascular disease 6 | 319
Waldenstrons macroglobulinemia 6 | 765
primary Sjogren syndrome 6 | 735
progressive supranuclear palsy 6 | 676
spina bifida 6 | 1,074
Alzheimer's disease 5 | 658
Atherosclerosis 5 | 291
Becker muscular dystrophy 5 | 191
Coronary artery disease 5 | 268
Heart disease 5 | 306
Intellectual disability 5 | 1,016
Proteinuria 5 | 144
active ulcerative colitis 5 | 764
acute quadriplegic myopathy 5 | 1,158
autosomal dominant Emery-Dreifuss muscular dystrophy 5 | 510
chronic lymphosyte leukemia 5 | 204
nephrosclerosis 5 | 333
periodontitis 5 | 293

Tissue

Digestive Tract 85 | 17,369
Liver and Pancreas 85 | 16,750
Blood and immune system 84 | 16,909
Cardiovascular System 84 | 15,192
Endocrine System 84 | 18,159
Female tissues 84 | 17,400
Respiratory system 84 | 16,393
Skin and soft tissues 84 | 17,230
Urinary Tract 84 | 16,678
Male tissues 83 | 17,142
Nervous System 81 | 16,725

Target Family

Non-IDG 62 | 12,091
Kinase 12 | 634
Enzyme 10 | 4,145
Transcription Factor 1 | 1,400

GO Process

integrin-mediated signaling pa... 85 | 85
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Integrin alpha-11 ITGA11 Tbio Non-IDG -1.13736 14.3 76
Tetraspanin-32 TSPAN32 Tbio Non-IDG -0.97140 8.31 153
PML-RARA-regulated adapter molecule 1 PRAM1 Tbio Non-IDG -2.18597 152.1 104
Zinc finger protein 304 ZNF304 Tbio Transcription Factor -0.83471 4.32 16
Disintegrin and metalloproteinase domain-containing protein 15 ADAM15 Tbio Enzyme -1.87408 84.1 301
Disintegrin and metalloproteinase domain-containing protein 9 ADAM9 Tchem Enzyme -2.08807 122.3 258
Megakaryocyte and platelet inhibitory receptor G6b MPIG6B Tbio Non-IDG -1.00429 11.8 53
Tyrosine-protein kinase TXK TXK Tchem Kinase -2.28365 191.1 194
A disintegrin and metalloproteinase with thrombospondin motifs 1 ADAMTS1 Tchem Enzyme -2.44459 279.8 227
Collagen alpha-1(XVI) chain COL16A1 Tbio Non-IDG -0.91124 6.99 35