Development Level

Tbio 7 | 11,651
Tclin 1 | 612
Tdark 1 | 6,593

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal craniofacial morpholo... 1 | 33
abnormal embryo size 1 | 220
abnormal eye morphology 1 | 68
abnormal forebrain morphology 1 | 10
abnormal hindbrain morphology 1 | 10
abnormal limb morphology 1 | 13
abnormal midbrain morphology 1 | 10
abnormal neural tube closure 1 | 46
anophthalmia 1 | 33
decreased monocyte cell number 1 | 8
decreased neutrophil cell numb... 1 | 42
edema 1 | 59
increased lymphocyte cell numb... 1 | 32
microphthalmia 1 | 26
persistence of hyaloid vascula... 1 | 33
polydactyly 1 | 7
tremors 1 | 39

Disease

Carcinoma 6 | 11,493
ovarian cancer 6 | 8,520
Intellectual disability 5 | 1,016
adult high grade glioma 4 | 3,801
ependymoma 4 | 4,679
glioblastoma 4 | 5,792
psoriasis 4 | 6,694
Acquired scoliosis 3 | 281
Autosomal recessive predisposition 3 | 1,442
Breast cancer 3 | 3,578
Curvature of spine 3 | 282
Oculocerebrorenal syndrome 3 | 29
Seizures 3 | 596
atypical teratoid / rhabdoid tumor 3 | 5,112
group 3 medulloblastoma 3 | 4,104
lung adenocarcinoma 3 | 2,716
lung cancer 3 | 4,740
medulloblastoma, large-cell 3 | 6,241
oligodendroglioma 3 | 2,850
osteosarcoma 3 | 7,950
Astrocytoma, Pilocytic 2 | 3,081
Bipolar Disorder 2 | 666
Cataract 2 | 297
Dermatologic disorders 2 | 93
Dull intelligence 2 | 645
Endometriosis 2 | 540
Epilepsy 2 | 792
Low intelligence 2 | 645
Melanoma 2 | 711
Mental Retardation 2 | 645
Mental deficiency 2 | 645
Neurodegenerative disease 2 | 414
Obesity 2 | 678
Parkinson's disease 2 | 392
Pick disease 2 | 1,894
Polydactyly 2 | 107
Poor school performance 2 | 645
Schizophrenia 2 | 1,160
Skin Diseases 2 | 71
Skin cancer 2 | 469
Squamous cell carcinoma 2 | 129
colon cancer 2 | 1,478
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
juvenile dermatomyositis 2 | 1,187
pancreatic cancer 2 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
tuberculosis 2 | 2,010
ulcerative colitis 2 | 1,819
Abnormal lung lobation 1 | 10
Abnormality of the penis 1 | 7
Abnormally prominent line of Schwalbe 1 | 2
Angioid streaks 1 | 11
Aqueductal Stenosis 1 | 5
Asymmetric chest 1 | 4
Bannayan-Riley-Ruvalcaba syndrome 1 | 8
Birth length greater than 97th percentile 1 | 5
Calvarial hyperostosis 1 | 5
Conjunctival hamartoma 1 | 7
Cowden disease 1 | 18
Cranial nerve palsies 1 | 11
Decreased facial expression 1 | 6
Decreased facial muscle movement 1 | 6
Dysmenorrhea 1 | 21
Endometrial Hyperplasia 1 | 5
Enlarged cerebellum 1 | 3
Enlargement of calvarial bones 1 | 5
Exostoses 1 | 11
Expressionless face 1 | 6
Fibrous skin tumor of tuberous sclerosis 1 | 18
Fissured tongue 1 | 25
Gait, Shuffling 1 | 8
Gastrointestinal hamartomatous polyps 1 | 10
Gastrointestinal polyps 1 | 5
Gingival recession 1 | 13
Haemorrhage subcutaneous 1 | 10
Hamartoma Syndrome, Multiple 1 | 10
Hamartomatous polyp 1 | 10
Hashimoto Disease 1 | 4
Headache disorder 1 | 19
Heterochromia iridis 1 | 9
Hyperkeratosis, generalized 1 | 14
Increased ossification of calvarial bones 1 | 5
Intestinal Polyposis 1 | 6
Leg Length Inequality 1 | 6
Lipomatosis 1 | 12
Macule 1 | 19
Marfanoid body habitus 1 | 11
Meningioma, familial 1 | 6
Mucosal telangiectasiae 1 | 14
Multiple lipomata 1 | 7
Multiple, subcutaneous nodules 1 | 53
NEVUS, EPIDERMAL (disorder) 1 | 5
Penile Diseases 1 | 3
Polyp of large intestine 1 | 8
Seizures, Febrile 1 | 7
Subcutaneous lipomas 1 | 9
Subcutaneous nodule 1 | 53
Thyroid Gland Follicular Adenoma 1 | 9
Thyroid adenoma 1 | 10
Thyroid cancer, follicular 1 | 8

Tissue

Blood and immune system 9 | 16,909
Cardiovascular System 9 | 15,192
Digestive Tract 9 | 17,369
Endocrine System 9 | 18,159
Female tissues 9 | 17,400
Liver and Pancreas 9 | 16,750
Male tissues 9 | 17,142
Nervous System 9 | 16,725
Respiratory system 9 | 16,393
Skin and soft tissues 9 | 17,230
Urinary Tract 9 | 16,678

Target Family

Enzyme 8 | 4,145
Non-IDG 1 | 12,091

GO Process

inositol phosphate dephosphory... 9 | 9
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Myotubularin-related protein 2 MTMR2 Tbio Enzyme -1.64906 46.5 124
Inositol polyphosphate 5-phosphatase K INPP5K Tbio Enzyme -0.93536 10.1 92
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN PTEN Tbio Enzyme -3.70874 5099.6 916
Inositol monophosphatase 2 IMPA2 Tbio Enzyme -1.49842 31.5 67
Synaptojanin-1 SYNJ1 Tbio Non-IDG -1.76329 62.0 93
Inositol monophosphatase 1 IMPA1 Tclin Enzyme -2.34557 211.7 94
Myotubularin-related protein 7 MTMR7 Tdark Enzyme -0.42461 3.79 39
72 kDa inositol polyphosphate 5-phosphatase INPP5E Tbio Enzyme -1.47845 28.1 63
Type I inositol 1,4,5-trisphosphate 5-phosphatase INPP5A Tbio Enzyme -1.32753 19.3 109