Development Level

Tbio 14 | 11,445
Tdark 1 | 6,588

IMPC Phenotype

increased circulating chloride... 2 | 41
abnormal nail morphology 1 | 8
abnormal snout morphology 1 | 23
abnormal tail movements 1 | 12
absent pinna reflex 1 | 23
curly tail 1 | 1
decreased body length 1 | 101
decreased circulating HDL chol... 1 | 68
decreased circulating amylase ... 1 | 28
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating potassiu... 1 | 20
decreased circulating serum al... 1 | 82
decreased circulating triglyce... 1 | 79
decreased grip strength 1 | 116
decreased lactate dehydrogenas... 1 | 16
decreased lymphocyte cell numb... 1 | 83
decreased total body fat amoun... 1 | 207
impaired righting response 1 | 26
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased bone mineral content 1 | 108
increased circulating sodium l... 1 | 71
increased lean body mass 1 | 172
increased neutrophil cell numb... 1 | 46
increased or absent threshold ... 1 | 101
increased thermal nociceptive ... 1 | 9
kinked tail 1 | 2
limb grasping 1 | 41
mammalian phenotype 1 | 17
mydriasis 1 | 6
preweaning lethality, complete... 1 | 979
stereotypic behavior 1 | 3
trunk curl 1 | 16

Disease

Carcinoma 10 | 11,493
ependymoma 8 | 4,679
medulloblastoma, large-cell 8 | 6,241
atypical teratoid / rhabdoid tumor 7 | 5,112
group 3 medulloblastoma 7 | 4,104
lung cancer 7 | 4,740
Retinitis Pigmentosa 6 | 226
osteosarcoma 6 | 7,950
ovarian cancer 6 | 8,520
Autosomal recessive predisposition 5 | 1,442
Nonsyndromic deafness 5 | 142
glioblastoma 5 | 5,792
invasive ductal carcinoma 5 | 2,951
psoriasis 5 | 6,694
Blindness 4 | 88
Breast cancer 4 | 3,578
Electroretinogram abnormal 4 | 95
Intellectual disability 4 | 1,016
Sensorineural hearing loss 4 | 106
Usher syndrome 4 | 32
adult high grade glioma 4 | 3,801
interstitial cystitis 4 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
non-small cell lung cancer 4 | 2,890
oligodendroglioma 4 | 2,850
pancreatic cancer 4 | 2,398
pituitary cancer 4 | 1,972
primitive neuroectodermal tumor 4 | 3,035
tuberculosis 4 | 2,010
Astrocytoma, Pilocytic 3 | 3,081
Bardet-Biedl syndrome 3 | 51
Cataract 3 | 297
Dull intelligence 3 | 645
Kidney cancer 3 | 2,613
Lens Opacities 3 | 231
Low intelligence 3 | 645
Mental Retardation 3 | 645
Mental deficiency 3 | 645
Poor school performance 3 | 645
Usher Syndrome, Type 1 3 | 7
Usher Syndrome, Type I 3 | 6
astrocytic glioma 3 | 2,597
cystic fibrosis 3 | 1,696
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
lung adenocarcinoma 3 | 2,716
lung carcinoma 3 | 2,843
malignant mesothelioma 3 | 3,232
primary pancreatic ductal adenocarcinoma 3 | 1,109
Abnormal vision 2 | 52
Anencephaly 2 | 26
Bipolar Disorder 2 | 666
Cancer 2 | 2,499
Carcinoma, Non-Small-Cell Lung 2 | 107
Cerebellar Ataxia 2 | 304
Cognitive delay 2 | 608
Congenital hypoplasia of ovary 2 | 30
Congenital hypoplasia of penis 2 | 176
Difficulties with night vision 2 | 87
Global developmental delay 2 | 608
Hemianopsia 2 | 15
Hydrocephalus 2 | 152
Hypertensive disease 2 | 292
Hypogonadism 2 | 173
Hypoplastic mandible condyle 2 | 275
Hypoplastic ovary 2 | 30
Increase in blood pressure 2 | 119
Liver cancer 2 | 604
Mandibular hypoplasia 2 | 275
Melanoma 2 | 711
Mental and motor retardation 2 | 608
Micrognathism 2 | 275
Multicystic Dysplastic Kidney 2 | 52
Night Blindness 2 | 101
Nystagmus 2 | 317
Obesity 2 | 678
Pigmentary iris degeneration 2 | 20
Polydactyly 2 | 107
Retinal blind spot 2 | 11
Scotoma 2 | 22
Sensorineural Hearing Loss (disorder) 2 | 284
Short neck 2 | 140
Short stature 2 | 531
Skin cancer 2 | 469
Small genitalia 2 | 13
Ulnar polydactyly of fingers 2 | 47
acute quadriplegic myopathy 2 | 1,158
adrenocortical carcinoma 2 | 1,428
breast carcinoma 2 | 1,638
cutaneous lupus erythematosus 2 | 1,057
ductal carcinoma in situ 2 | 1,745
esophageal adenocarcinoma 2 | 737
gastric carcinoma 2 | 807
group 4 medulloblastoma 2 | 1,855
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
non-small cell lung carcinoma 2 | 317
urothelial carcinoma 2 | 318
Hypoplastic feet 1 | 66
Pre-Eclampsia 1 | 68
USHER SYNDROME, TYPE ID 1 | 2
Usher syndrome, type 1D 1 | 2

Tissue

Endocrine System 15 | 18,159
Male tissues 15 | 17,142
Blood and immune system 14 | 16,909
Digestive Tract 14 | 17,369
Female tissues 14 | 17,400
Respiratory system 14 | 16,393
Skin and soft tissues 14 | 17,230
Urinary Tract 14 | 16,678
Cardiovascular System 13 | 15,192
Liver and Pancreas 13 | 16,750
Nervous System 13 | 16,725

Target Family

Non-IDG 12 | 12,091
Transcription Factor 2 | 1,400
Enzyme 1 | 4,145

GO Process

inner ear receptor stereociliu... 15 | 15
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Harmonin USH1C Tbio Non-IDG -2.10689 124.7 188
Meckel syndrome type 1 protein MKS1 Tbio Non-IDG -1.31837 20.5 59
Transcription factor HES-5 HES5 Tbio Transcription Factor -2.08501 97.6 139
Glutaredoxin domain-containing cysteine-rich protein 1 GRXCR1 Tdark Non-IDG -0.45230 3.09 43
Whirlin WHRN Tbio Non-IDG -1.74958 54.1 123
Protocadherin Fat 4 FAT4 Tbio Non-IDG -1.70369 49.6 50
Collagen triple helix repeat-containing protein 1 CTHRC1 Tbio Non-IDG -1.72221 62.3 202
Cadherin-23 CDH23 Tbio Non-IDG -2.01011 103.6 189
Transcription factor HES-1 HES1 Tbio Transcription Factor -1.77409 55.5 444
Syndecan-4 SDC4 Tbio Non-IDG -2.39649 274.8 297