Development Level

Tbio 46 | 11,445
Tchem 5 | 1,598
Tclin 4 | 613

Collection

Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

decreased body weight 4 | 161
abnormal behavior 3 | 298
abnormal embryo size 3 | 220
embryonic lethality prior to t... 3 | 278
hyperactivity 3 | 148
increased lean body mass 3 | 172
preweaning lethality, complete... 3 | 979
decreased circulating glucose ... 2 | 126
decreased circulating insulin ... 2 | 76
decreased circulating triglyce... 2 | 79
decreased grip strength 2 | 116
decreased prepulse inhibition 2 | 82
embryonic growth retardation 2 | 106
increased bone mineral content 2 | 108
increased circulating sodium l... 2 | 71
increased or absent threshold ... 2 | 101
increased startle reflex 2 | 112
preweaning lethality, incomple... 2 | 499
abnormal body wall morphology 1 | 9
abnormal epididymis morphology 1 | 42
abnormal gait 1 | 69
abnormal head morphology 1 | 10
abnormal kidney morphology 1 | 65
abnormal locomotor activation 1 | 16
abnormal ovary morphology 1 | 7
abnormal retinal vasculature m... 1 | 27
abnormal snout morphology 1 | 23
abnormal startle reflex 1 | 15
absent epididymis 1 | 3
absent pinna reflex 1 | 23
cataract 1 | 92
cleft palate 1 | 8
decreased body length 1 | 101
decreased circulating HDL chol... 1 | 68
decreased circulating alanine ... 1 | 47
decreased circulating amylase ... 1 | 28
decreased circulating aspartat... 1 | 34
decreased circulating choleste... 1 | 93
decreased circulating free fat... 1 | 31
decreased circulating fructosa... 1 | 30
decreased circulating potassiu... 1 | 20
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased hematocrit 1 | 46
decreased lean body mass 1 | 135
decreased lumbar vertebrae num... 1 | 2
decreased spleen weight 1 | 10
decreased startle reflex 1 | 75
decreased threshold for audito... 1 | 26
decreased total body fat amoun... 1 | 207
embryonic lethality prior to o... 1 | 239
enlarged heart 1 | 210
enlarged kidney 1 | 14
impaired glucose tolerance 1 | 75
impaired righting response 1 | 26
improved glucose tolerance 1 | 79
increased circulating HDL chol... 1 | 80
increased circulating chloride... 1 | 41
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased circulating triglyce... 1 | 42
increased mean corpuscular hem... 1 | 36
increased total body fat amoun... 1 | 134
limb grasping 1 | 41
mammalian phenotype 1 | 17
polycystic kidney 1 | 15
prenatal lethality 1 | 28
prenatal lethality prior to he... 1 | 87
stereotypic behavior 1 | 3
trunk curl 1 | 16

Disease

Carcinoma 41 | 11,493
psoriasis 29 | 6,694
osteosarcoma 27 | 7,950
atypical teratoid / rhabdoid tumor 26 | 5,112
glioblastoma 23 | 5,792
lung cancer 23 | 4,740
medulloblastoma, large-cell 22 | 6,241
ovarian cancer 21 | 8,520
Breast cancer 20 | 3,578
Autosomal recessive predisposition 18 | 1,442
Cancer 17 | 2,499
Astrocytoma, Pilocytic 16 | 3,081
Cleft Palate 15 | 271
ependymoma 15 | 4,679
malignant mesothelioma 15 | 3,232
Kidney cancer 14 | 2,613
adult high grade glioma 14 | 3,801
invasive ductal carcinoma 14 | 2,951
lung carcinoma 13 | 2,843
non-small cell lung cancer 13 | 2,890
oligodendroglioma 13 | 2,850
pituitary cancer 13 | 1,972
Craniofacial Abnormalities 12 | 151
Intellectual disability 12 | 1,016
Sensorineural Hearing Loss (disorder) 12 | 284
group 3 medulloblastoma 12 | 4,104
Dull intelligence 11 | 645
Low intelligence 11 | 645
Mental Retardation 11 | 645
Mental deficiency 11 | 645
Poor school performance 11 | 645
Sensorineural hearing loss 11 | 106
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,291
lung adenocarcinoma 11 | 2,716
Orbital separation excessive 10 | 244
Short stature 10 | 531
cystic fibrosis 10 | 1,696
Cognitive delay 9 | 608
Congenital deafness 9 | 185
Deafness 9 | 198
Global developmental delay 9 | 608
Hearing Loss, Partial 9 | 185
Hypoplastic mandible condyle 9 | 275
Mandibular hypoplasia 9 | 275
Mental and motor retardation 9 | 608
Micrognathism 9 | 275
Schizophrenia 9 | 1,160
Uranostaphyloschisis 9 | 167
breast carcinoma 9 | 1,638
ductal carcinoma in situ 9 | 1,745
hearing impairment 9 | 199
interstitial cystitis 9 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,989
primitive neuroectodermal tumor 9 | 3,035
subependymal giant cell astrocytoma 9 | 2,287
Cleft Lip 8 | 141
Concave bridge of nose 8 | 195
Depressed nasal bridge 8 | 195
Depressed nasal root/bridge 8 | 195
Downward slant of palpebral fissure 8 | 158
Epilepsy 8 | 792
Exophthalmos 8 | 112
Hypotrophic malar bone 8 | 129
Low set ears 8 | 181
Malar flattening 8 | 129
Nonsyndromic deafness 8 | 142
Prominent eyes 8 | 96
Prominent globes 8 | 96
Protruding eyes 8 | 96
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
pancreatic cancer 8 | 2,398
Bilateral fifth finger clinodactyly 7 | 110
Curvature of little finger 7 | 110
Long philtrum 7 | 137
Muscle hypotonia 7 | 571
Seizures 7 | 596
Strabismus 7 | 270
adrenocortical carcinoma 7 | 1,428
astrocytic glioma 7 | 2,597
group 4 medulloblastoma 7 | 1,855
Anteverted nostril 6 | 191
Conductive hearing loss 6 | 123
Decreased projection of midface 6 | 105
Frontal bossing 6 | 157
Hypotrophic midface 6 | 105
Low-set, posteriorly rotated ears 6 | 110
Midface retrusion 6 | 105
Pick disease 6 | 1,894
Short nose 6 | 132
Small midface 6 | 105
Small nose 6 | 132
cutaneous lupus erythematosus 6 | 1,057
gastric carcinoma 6 | 807
Abnormally small eyeball 5 | 97
Bipolar Disorder 5 | 666
Decreased size of eyeball 5 | 97
colon cancer 5 | 1,478
nephrosclerosis 5 | 333
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
spina bifida 5 | 1,074

Tissue

Digestive Tract 50 | 17,369
Endocrine System 49 | 18,159
Female tissues 49 | 17,400
Skin and soft tissues 48 | 17,230
Male tissues 46 | 17,142
Blood and immune system 45 | 16,909
Urinary Tract 45 | 16,678
Nervous System 44 | 16,725
Respiratory system 44 | 16,393
Liver and Pancreas 42 | 16,750
Cardiovascular System 33 | 15,192

Target Family

Transcription Factor 22 | 1,400
Non-IDG 19 | 12,091
Kinase 4 | 634
GPCR 3 | 408
Ion Channel 3 | 344
Enzyme 2 | 4,145
Epigenetic 1 | 242
Transporter 1 | 473

GO Process

inner ear morphogenesis 55 | 55
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Paired mesoderm homeobox protein 1 PRRX1 Tbio Transcription Factor -1.58479 38.8 304
Unconventional myosin-XV MYO15A Tbio Non-IDG -1.64094 42.8 15
Insulin-induced gene 2 protein INSIG2 Tbio Non-IDG -1.94599 88.7 78
Harmonin USH1C Tbio Non-IDG -2.10689 124.7 188
Transcription factor MafB MAFB Tbio Transcription Factor -2.01655 101.2 191
Homeobox protein SIX4 SIX4 Tbio Transcription Factor -2.31722 197.8 141
Collagen alpha-1(XI) chain COL11A1 Tbio Non-IDG -2.15516 138.4 96
T-box transcription factor TBX1 TBX1 Tbio Transcription Factor -1.99519 95.5 207
Cadherin EGF LAG seven-pass G-type receptor 1 CELSR1 Tbio GPCR -1.47924 34.4 115
TRAF-interacting protein with FHA domain-containing protein B TIFAB Tbio Non-IDG -0.55328 2.93 54