Development Level

Tbio 37 | 11,445
Tchem 6 | 1,598
Tclin 2 | 613
Tdark 1 | 6,588

IMPC Phenotype

decreased body weight 3 | 161
preweaning lethality, complete... 3 | 979
decreased lean body mass 2 | 135
increased circulating iron lev... 2 | 30
abnormal bone structure 1 | 187
abnormal clavicle morphology 1 | 6
abnormal coat-hair pigmentatio... 1 | 64
abnormal eating behavior 1 | 1
abnormal eye morphology 1 | 68
abnormal forced expiratory flo... 1 | 1
abnormal humerus morphology 1 | 11
abnormal incisor color 1 | 3
abnormal joint morphology 1 | 23
abnormal lens morphology 1 | 81
abnormal optic disc morphology 1 | 10
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal testis morphology 1 | 43
abnormal tibia morphology 1 | 14
abnormal tooth morphology 1 | 24
abnormal whole-body plethysmog... 1 | 4
altered righting response 1 | 1
cataract 1 | 92
decreased body length 1 | 101
decreased body temperature 1 | 2
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating iron lev... 1 | 32
decreased eosinophil cell numb... 1 | 24
decreased heart weight 1 | 27
decreased mean corpuscular hem... 1 | 31
decreased tidal volume 1 | 1
edema 1 | 59
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
enlarged lymph nodes 1 | 37
impaired glucose tolerance 1 | 75
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased circulating glucose ... 1 | 24
increased fasted circulating g... 1 | 76
increased grip strength 1 | 41
increased heart weight 1 | 62
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased monocyte cell number 1 | 63
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
limb grasping 1 | 41

Disease

Carcinoma 29 | 11,493
glioblastoma 26 | 5,792
medulloblastoma, large-cell 25 | 6,241
ependymoma 21 | 4,679
ovarian cancer 20 | 8,520
Astrocytoma, Pilocytic 19 | 3,081
Cancer 19 | 2,499
group 3 medulloblastoma 19 | 4,104
atypical teratoid / rhabdoid tumor 18 | 5,112
psoriasis 18 | 6,694
adult high grade glioma 17 | 3,801
lung adenocarcinoma 17 | 2,716
Breast cancer 16 | 3,578
astrocytic glioma 15 | 2,597
cystic fibrosis 15 | 1,696
primitive neuroectodermal tumor 15 | 3,035
lung carcinoma 14 | 2,843
invasive ductal carcinoma 13 | 2,951
interstitial cystitis 12 | 2,312
oligodendroglioma 12 | 2,850
Short stature 11 | 531
lung cancer 11 | 4,740
non-small cell lung cancer 11 | 2,890
osteosarcoma 11 | 7,950
pancreatic cancer 11 | 2,398
Autosomal recessive predisposition 10 | 1,442
Sensorineural Hearing Loss (disorder) 10 | 284
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,291
breast carcinoma 9 | 1,638
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,989
malignant mesothelioma 9 | 3,232
subependymal giant cell astrocytoma 9 | 2,287
ulcerative colitis 9 | 1,819
Cleft Palate 8 | 271
ductal carcinoma in situ 8 | 1,745
nasopharyngeal carcinoma 8 | 1,058
pituitary cancer 8 | 1,972
Kidney cancer 7 | 2,613
Liver Cirrhosis, Experimental 7 | 769
Muscle hypotonia 7 | 571
Nonsyndromic deafness 7 | 142
adrenocortical carcinoma 7 | 1,428
astrocytoma 7 | 1,146
colon cancer 7 | 1,478
group 4 medulloblastoma 7 | 1,855
primary pancreatic ductal adenocarcinoma 7 | 1,109
Cognitive delay 6 | 608
Deafness 6 | 198
Epilepsy 6 | 792
Global developmental delay 6 | 608
Mental and motor retardation 6 | 608
Multiple myeloma 6 | 1,332
Schizophrenia 6 | 1,160
diabetes mellitus 6 | 1,728
esophageal adenocarcinoma 6 | 737
pediatric high grade glioma 6 | 1,064
Atopic dermatitis 5 | 952
Carcinoma, Hepatocellular 5 | 228
Congenital deafness 5 | 185
Down syndrome 5 | 499
Dull intelligence 5 | 645
Exophthalmos 5 | 112
Hearing Loss, Partial 5 | 185
Intellectual disability 5 | 1,016
Liver Cirrhosis 5 | 181
Liver carcinoma 5 | 240
Low intelligence 5 | 645
Lung Neoplasms 5 | 232
Mental Retardation 5 | 645
Mental deficiency 5 | 645
Poor school performance 5 | 645
Prominent eyes 5 | 96
Prominent globes 5 | 96
Protruding eyes 5 | 96
Seizures 5 | 596
Squamous cell carcinoma 5 | 129
Strabismus 5 | 270
cutaneous lupus erythematosus 5 | 1,057
gastric carcinoma 5 | 807
hearing impairment 5 | 199
juvenile dermatomyositis 5 | 1,187
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
spina bifida 5 | 1,074
Acquired scoliosis 4 | 281
Byzanthine arch palate 4 | 194
Coronary artery disease 4 | 268
Curvature of spine 4 | 282
Downward slant of palpebral fissure 4 | 158
Hepatomegaly 4 | 285
Myopia 4 | 176
Pick disease 4 | 1,894
Sensorineural hearing loss 4 | 106
Uranostaphyloschisis 4 | 167
acute quadriplegic myopathy 4 | 1,158
dermatomyositis 4 | 966
limb girdle muscular dystrophy 2A 4 | 213
medulloblastoma 4 | 720
tuberculosis 4 | 2,010
urothelial carcinoma 4 | 318

Tissue

Digestive Tract 44 | 17,369
Endocrine System 44 | 18,159
Skin and soft tissues 44 | 17,230
Female tissues 43 | 17,400
Liver and Pancreas 42 | 16,750
Urinary Tract 42 | 16,678
Blood and immune system 41 | 16,909
Male tissues 41 | 17,142
Nervous System 41 | 16,725
Respiratory system 41 | 16,393
Cardiovascular System 35 | 15,192

Target Family

Non-IDG 25 | 12,091
Transcription Factor 10 | 1,400
Enzyme 4 | 4,145
Kinase 3 | 634
GPCR 1 | 408
Ion Channel 1 | 344
Nuclear Receptor 1 | 48
Transporter 1 | 473

GO Process

inner ear development 46 | 46
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protocadherin-15 PCDH15 Tbio Non-IDG -1.83877 74.3 42
Steroid hormone receptor ERR2 ESRRB Tchem Nuclear Receptor -1.95523 86.9 173
Mitochondrial uncoupling protein 4 SLC25A27 Tbio Transporter -1.53936 38.0 51
BMP-binding endothelial regulator protein BMPER Tbio Non-IDG -2.51174 317.7 120
Potassium voltage-gated channel subfamily KQT member 1 KCNQ1 Tclin Ion Channel -2.90675 800.2 365
TRAF-interacting protein with FHA domain-containing protein B TIFAB Tbio Non-IDG -0.55328 2.93 54
Bone morphogenetic protein 2 BMP2 Tbio Non-IDG -3.65728 4647.9 684
Complement C1q tumor necrosis factor-related protein 5 C1QTNF5 Tbio Non-IDG -0.39794 1.27 209
Inactive tyrosine-protein kinase transmembrane receptor ROR1 ROR1 Tbio Kinase -1.38904 30.7 332
CCAAT/enhancer-binding protein delta CEBPD Tbio Transcription Factor -2.49029 299.9 179