Development Level

Tbio 273 | 10,625
Tchem 66 | 1,890
Tdark 48 | 7,003
Tclin 23 | 602

IMPC Term

preweaning lethality, complete... 6 | 633
embryonic lethality prior to t... 5 | 187
decreased bone mineral content 4 | 157
decreased total body fat amoun... 4 | 186
increased circulating HDL chol... 4 | 63
abnormal behavior 3 | 226
abnormal embryo size 3 | 112
abnormal seminal vesicle morph... 3 | 47
decreased circulating glucose ... 3 | 121
decreased grip strength 3 | 123
embryonic lethality prior to o... 3 | 148
increased bone mineral content 3 | 92
increased circulating choleste... 3 | 53
abnormal bone structure 2 | 131
abnormal locomotor activation 2 | 26
abnormal neural tube closure 2 | 37
decreased bone mineral density 2 | 126
decreased circulating alanine ... 2 | 53
decreased circulating amylase ... 2 | 24
decreased circulating magnesiu... 2 | 11
decreased circulating triglyce... 2 | 83
decreased lean body mass 2 | 195
decreased mean corpuscular hem... 2 | 19
decreased mean corpuscular vol... 2 | 50
enlarged heart 2 | 111
hypoactivity 2 | 89
increased leukocyte cell numbe... 2 | 37
increased mean corpuscular hem... 2 | 93
increased mean corpuscular vol... 2 | 91
preweaning lethality, incomple... 2 | 260
tremors 2 | 34
abnormal coping response 1 | 12
abnormal cornea morphology 1 | 24
abnormal femur morphology 1 | 14
abnormal forebrain development 1 | 18
abnormal gait 1 | 51
abnormal hair growth 1 | 8
abnormal hindbrain development 1 | 24
abnormal joint morphology 1 | 14
abnormal lens morphology 1 | 73
abnormal midbrain development 1 | 22
abnormal rib morphology 1 | 28
abnormal tail movements 1 | 12
abnormal testis morphology 1 | 30
abnormal tooth morphology 1 | 24
absent vibrissae 1 | 14
cataract 1 | 26
decreased CD8-positive, alpha-... 1 | 26
decreased NK cell number 1 | 16
decreased T cell number 1 | 31
decreased blood urea nitrogen ... 1 | 31
decreased body length 1 | 108
decreased circulating bilirubi... 1 | 14
decreased circulating serum al... 1 | 79
decreased circulating sodium l... 1 | 18
decreased eosinophil cell numb... 1 | 41
decreased fasted circulating g... 1 | 49
decreased heart weight 1 | 44
decreased mean corpuscular hem... 1 | 34
decreased neutrophil cell numb... 1 | 37
decreased prepulse inhibition 1 | 52
decreased rib number 1 | 59
enlarged lymph nodes 1 | 27
female infertility 1 | 34
hyperactivity 1 | 108
impaired righting response 1 | 19
increased CD4-positive, alpha ... 1 | 15
increased NK cell number 1 | 19
increased blood urea nitrogen ... 1 | 44
increased body weight 1 | 42
increased bone mineral density 1 | 52
increased circulating alanine ... 1 | 11
increased circulating alkaline... 1 | 119
increased circulating aspartat... 1 | 17
increased circulating calcium ... 1 | 32
increased circulating glucose ... 1 | 16
increased circulating magnesiu... 1 | 10
increased circulating sodium l... 1 | 71
increased circulating total pr... 1 | 20
increased circulating triglyce... 1 | 24
increased eosinophil cell numb... 1 | 9
increased fasted circulating g... 1 | 68
increased heart weight 1 | 37
increased lactate dehydrogenas... 1 | 3
increased lean body mass 1 | 107
increased mean platelet volume 1 | 19
increased or absent threshold ... 1 | 128
increased rib number 1 | 41
increased spleen weight 1 | 3
oligodactyly 1 | 14
pale yolk sac 1 | 12
pallor 1 | 13
persistence of hyaloid vascula... 1 | 22
premature death 1 | 5
small adrenal glands 1 | 15
small superior vagus ganglion 1 | 20
small testis 1 | 37
stereotypic behavior 1 | 3
thrombocytopenia 1 | 46
trunk curl 1 | 15

Disease

osteosarcoma 175 | 7,933
ovarian cancer 171 | 8,484
psoriasis 170 | 6,685
lung cancer 135 | 4,466
glioblastoma 119 | 5,572
Cancer 114 | 2,346
lung carcinoma 112 | 2,844
medulloblastoma, large-cell 108 | 6,234
interstitial cystitis 93 | 2,299
ulcerative colitis 88 | 2,087
intraductal papillary-mucinous neoplasm (IPMN) 86 | 3,289
tuberculosis 81 | 1,557
pilocytic astrocytoma 75 | 3,086
lung adenocarcinoma 74 | 2,713
cutaneous lupus erythematosus 73 | 1,056
pancreatic cancer 72 | 2,300
intraductal papillary-mucinous adenoma (IPMA) 71 | 2,956
malignant mesothelioma 71 | 3,162
non-small cell lung cancer 71 | 2,798
intraductal papillary-mucinous carcinoma (IPMC) 69 | 2,988
subependymal giant cell astrocytoma 68 | 2,287
invasive ductal carcinoma 64 | 2,950
Rheumatoid Arthritis 53 | 1,160
atypical teratoid / rhabdoid tumor 53 | 4,369
cystic fibrosis 53 | 1,665
Breast cancer 49 | 3,094
adult high grade glioma 49 | 2,148
diabetes mellitus 47 | 1,663
juvenile dermatomyositis 47 | 1,189
pediatric high grade glioma 47 | 2,712
astrocytoma 46 | 1,493
primary Sjogren syndrome 44 | 789
dermatomyositis 43 | 933
Carcinoma 41 | 2,147
pituitary cancer 38 | 1,972
group 4 medulloblastoma 37 | 1,875
mucosa-associated lymphoid tissue lymphoma 36 | 480
oligodendroglioma 36 | 2,849
posterior fossa group A ependymoma 36 | 1,511
Multiple myeloma 34 | 1,327
adrenocortical carcinoma 33 | 1,427
esophageal adenocarcinoma 33 | 737
group 3 medulloblastoma 33 | 2,254
active Crohn's disease 32 | 918
pancreatic ductal adenocarcinoma liver metastasis 32 | 1,795
Atopic dermatitis 31 | 944
Multiple Sclerosis 31 | 498
IGA Glomerulonephritis 30 | 454
ductal carcinoma in situ 30 | 1,745
ependymoma 30 | 2,514
breast carcinoma 26 | 1,614
colon cancer 26 | 1,475
primary pancreatic ductal adenocarcinoma 26 | 1,271
primitive neuroectodermal tumor 26 | 3,031
astrocytic glioma 25 | 2,241
systemic lupus erythematosus 25 | 156
Arthritis 24 | 248
acute quadriplegic myopathy 24 | 1,157
Influenza 23 | 142
Lupus erythematosus 22 | 80
Waldenstrons macroglobulinemia 22 | 765
gastric carcinoma 22 | 832
pancreatic carcinoma 22 | 567
Kidney disease 21 | 396
head and neck cancer and chronic obstructive pulmonary disease 21 | 237
nasopharyngeal carcinoma 21 | 1,056
Duchenne muscular dystrophy 20 | 602
Pick disease 20 | 1,893
chronic lymphosyte leukemia 20 | 232
medulloblastoma 20 | 1,524
periodontitis 20 | 269
spina bifida 20 | 1,064
Asthma 19 | 349
Down syndrome 19 | 548
Alzheimer's disease 18 | 644
Blastic phase chronic myeloid leukemia 18 | 58
Chronic Myelocytic Leukemia Accelerated Phase 18 | 59
Inflammatory bowel disease 18 | 142
Melanoma 18 | 261
Prostatic Neoplasms 18 | 471
Schizophrenia 18 | 501
sonic hedgehog group medulloblastoma 17 | 1,482
Chronic phase chronic myeloid leukemia 16 | 45
Hypersensitivity reaction type II disease 16 | 235
Philadelphia Chromosome Positive Chronic Myelocytic Leukemia 16 | 45
Philadelphia chromosome-positive acute lymphoblastic leukemia 16 | 47
Vascular disease 16 | 281
acute myeloid leukemia 16 | 780
aldosterone-producing adenoma 16 | 664
posterior fossa group B ependymoma 16 | 1,530
gastric cancer 15 | 430
hepatocellular carcinoma 15 | 532
non primary Sjogren syndrome sicca 15 | 840
tuberculosis and treatment for 6 months 15 | 686
Atherosclerosis 14 | 275
Crohn's disease 14 | 304
Dermatitis 14 | 107
Inflammation 14 | 109
Obesity 14 | 616
active ulcerative colitis 14 | 477

Tissue

Female tissues 371 | 18,647
Nervous System 370 | 18,561
Digestive Tract 366 | 18,473
Urinary Tract 364 | 18,444
Blood and immune system 360 | 17,995
Endocrine System 360 | 18,512
Skin and soft tissues 356 | 18,115
Cardiovascular System 352 | 17,958
Liver and Pancreas 348 | 18,136
Respiratory system 340 | 17,484
Male tissues 339 | 17,969

Target Family

Non-IDG 283 | 11,971
Enzyme 57 | 4,146
Kinase 49 | 634
Transcription Factor 12 | 1,400
GPCR 3 | 406
Epigenetic 2 | 242
Nuclear Receptor 2 | 48
Ion Channel 1 | 341
TF/Epigenetic 1 | 38

GO Process

innate immune response 410 | 410
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Zinc finger and BTB domain-containing protein 1 ZBTB1 Tbio Transcription Factor -0.57513 5.01 57
Antileukoproteinase SLPI Tbio Enzyme -2.56514 434.2 290
Interleukin-1 receptor-associated kinase 1 IRAK1 Tchem Kinase -2.51851 320.4 729
Natural killer cell receptor 2B4 CD244 Tbio Non-IDG -2.27438 190.1 418
Angiogenin ANG Tbio Enzyme -2.89794 796.0 203
Interferon lambda-1 IFNL1 Tbio Non-IDG -1.90881 86.4 137
F-actin-capping protein subunit alpha-1 CAPZA1 Tbio Non-IDG -1.28182 20.1 139
HLA class I histocompatibility antigen, B-38 alpha chain HLA-B Tbio Non-IDG 1568.8 0
E3 ubiquitin-protein ligase TRIM31 TRIM31 Tbio Enzyme -2.12276 133.1 126
Fibrinogen alpha chain FGA Tbio Non-IDG -2.84597 716.2 457