Development Level

Tbio 131 | 10,625
Tchem 30 | 1,890
Tclin 11 | 602
Tdark 6 | 7,003

IMPC Term

preweaning lethality, complete... 19 | 633
embryonic lethality prior to t... 8 | 187
increased or absent threshold ... 5 | 128
abnormal behavior 4 | 226
abnormal embryo size 4 | 112
embryonic lethality prior to o... 4 | 148
small testis 4 | 37
abnormal neural tube closure 3 | 37
decreased blood urea nitrogen ... 3 | 31
decreased body length 3 | 108
decreased circulating insulin ... 3 | 75
decreased lean body mass 3 | 195
enlarged heart 3 | 111
increased circulating HDL chol... 3 | 63
prenatal lethality prior to he... 3 | 64
preweaning lethality, incomple... 3 | 260
abnormal bone mineralization 2 | 55
abnormal bone structure 2 | 131
abnormal coat appearance 2 | 25
abnormal forebrain development 2 | 18
abnormal hindbrain development 2 | 24
abnormal midbrain development 2 | 22
abnormal pericardium morpholog... 2 | 11
abnormal placenta size 2 | 10
abnormal spleen morphology 2 | 36
abnormal startle reflex 2 | 14
abnormal testis morphology 2 | 30
decreased body weight 2 | 174
decreased bone mineral density 2 | 126
decreased circulating HDL chol... 2 | 77
decreased circulating alanine ... 2 | 53
decreased circulating choleste... 2 | 85
decreased eosinophil cell numb... 2 | 41
decreased grip strength 2 | 123
increased body weight 2 | 42
increased lean body mass 2 | 107
pale yolk sac 2 | 12
pallor 2 | 13
small spleen 2 | 11
abnormal QRS complex 1 | 25
abnormal cervical vertebrae mo... 1 | 4
abnormal coat/ hair morphology 1 | 18
abnormal coat/hair pigmentatio... 1 | 54
abnormal embryo development 1 | 2
abnormal embryo turning 1 | 15
abnormal facial morphology 1 | 9
abnormal gait 1 | 51
abnormal head morphology 1 | 10
abnormal lung morphology 1 | 15
abnormal optic disc morphology 1 | 10
abnormal response to new envir... 1 | 8
abnormal retina morphology 1 | 100
abnormal rib morphology 1 | 28
abnormal skin appearance 1 | 8
abnormal skin coloration 1 | 18
abnormal skin morphology 1 | 23
abnormal tooth morphology 1 | 24
absent heartbeat 1 | 6
absent startle reflex 1 | 15
cardiovascular system phenotyp... 1 | 35
cleft palate 1 | 6
corneal opacity 1 | 25
cyanosis 1 | 6
decreased Ly6C high monocyte n... 1 | 18
decreased bone mineral content 1 | 157
decreased circulating LDL chol... 1 | 37
decreased circulating creatini... 1 | 31
decreased circulating glycerol... 1 | 19
decreased circulating serum al... 1 | 79
decreased circulating triglyce... 1 | 83
decreased lumbar vertebrae num... 1 | 62
decreased monocyte cell number 1 | 28
decreased neutrophil cell numb... 1 | 37
decreased startle reflex 1 | 48
edema 1 | 11
female infertility 1 | 34
hemorrhage 1 | 12
hydrops fetalis 1 | 22
hyperactivity 1 | 108
improved glucose tolerance 1 | 56
increased bone mineral density 1 | 52
increased circulating alkaline... 1 | 119
increased circulating calcium ... 1 | 32
increased circulating triglyce... 1 | 24
increased exploration in new e... 1 | 56
increased grip strength 1 | 83
increased heart rate variabili... 1 | 4
increased heart weight 1 | 37
increased leukocyte cell numbe... 1 | 37
increased mean corpuscular vol... 1 | 91
increased prepulse inhibition 1 | 21
increased respiratory quotient 1 | 12
increased total body fat amoun... 1 | 57
irregularly shaped pupil 1 | 7
limb grasping 1 | 35
prenatal lethality 1 | 16
small adrenal glands 1 | 15
small kidney 1 | 10
small superior vagus ganglion 1 | 20
urinary bladder obstruction 1 | 2

Disease

ovarian cancer 103 | 8,492
osteosarcoma 91 | 7,933
psoriasis 77 | 6,685
medulloblastoma, large-cell 69 | 6,234
glioblastoma 68 | 5,572
lung cancer 65 | 4,473
Cancer 59 | 2,346
atypical teratoid / rhabdoid tumor 55 | 4,369
malignant mesothelioma 48 | 3,163
Breast cancer 45 | 3,099
Carcinoma 45 | 2,147
invasive ductal carcinoma 44 | 2,950
lung adenocarcinoma 40 | 2,714
intraductal papillary-mucinous adenoma (IPMA) 39 | 2,956
intraductal papillary-mucinous neoplasm (IPMN) 38 | 3,289
pediatric high grade glioma 36 | 2,712
non-small cell lung cancer 35 | 2,798
pilocytic astrocytoma 35 | 3,086
group 4 medulloblastoma 34 | 1,875
intraductal papillary-mucinous carcinoma (IPMC) 34 | 2,988
pituitary cancer 33 | 1,972
pancreatic cancer 32 | 2,300
lung carcinoma 31 | 2,844
oligodendroglioma 30 | 2,849
primitive neuroectodermal tumor 29 | 3,031
breast carcinoma 28 | 1,614
interstitial cystitis 28 | 2,299
pancreatic ductal adenocarcinoma liver metastasis 28 | 1,795
ependymoma 26 | 2,514
ulcerative colitis 26 | 2,087
astrocytic glioma 25 | 2,241
ductal carcinoma in situ 24 | 1,745
acute quadriplegic myopathy 23 | 1,157
cystic fibrosis 23 | 1,670
posterior fossa group A ependymoma 23 | 1,511
Pick disease 22 | 1,893
adrenocortical carcinoma 21 | 1,427
adult high grade glioma 21 | 2,148
group 3 medulloblastoma 21 | 2,254
subependymal giant cell astrocytoma 21 | 2,287
primary pancreatic ductal adenocarcinoma 20 | 1,271
astrocytoma 19 | 1,493
juvenile dermatomyositis 19 | 1,189
tuberculosis 19 | 1,563
atypical teratoid/rhabdoid tumor 18 | 1,095
dermatomyositis 18 | 967
diabetes mellitus 18 | 1,663
sonic hedgehog group medulloblastoma 18 | 1,482
Mammary Neoplasms 17 | 410
Multiple myeloma 17 | 1,328
posterior fossa group B ependymoma 17 | 1,530
Heart disease 16 | 279
colon cancer 16 | 1,475
spina bifida 16 | 1,064
Craniofacial Abnormalities 15 | 147
non-small cell lung carcinoma 15 | 413
Intellectual disability 14 | 573
Kidney disease 14 | 397
medulloblastoma 14 | 1,524
Alzheimer's disease 13 | 644
Atopic dermatitis 12 | 944
Cleft palate 12 | 125
Hypertension 12 | 293
Prostatic Neoplasms 12 | 471
active Crohn's disease 12 | 918
nasopharyngeal carcinoma 12 | 1,056
Rheumatoid Arthritis 11 | 1,171
cutaneous lupus erythematosus 11 | 1,056
gastric carcinoma 11 | 832
Cerebrovascular disease 10 | 231
Cleft Lip 10 | 91
Down syndrome 10 | 548
Obesity 10 | 616
Stomach Neoplasms 10 | 282
Vascular disease 10 | 281
Waldenstrons macroglobulinemia 10 | 765
non primary Sjogren syndrome sicca 10 | 840
Adenoma 9 | 165
Duchenne muscular dystrophy 9 | 602
autosomal dominant Emery-Dreifuss muscular dystrophy 9 | 499
esophageal adenocarcinoma 9 | 737
Atherosclerosis 8 | 275
Endometriosis 8 | 535
Liver Cirrhosis, Experimental 8 | 108
Neurodegenerative disease 8 | 383
Polycystic Ovary Syndrome 8 | 335
Polydactyly 8 | 93
acute myeloid leukemia 8 | 785
fibroadenoma 8 | 557
hepatocellular carcinoma 8 | 550
primary Sjogren syndrome 8 | 789
Amyotrophic Lateral Sclerosis 7 | 432
Diabetes Mellitus, Non-Insulin-Dependent 7 | 161
Hypertensive disease 7 | 193
IGA Glomerulonephritis 7 | 454
Neuropathy 7 | 210
chronic rhinosinusitis 7 | 512
gastric cancer 7 | 436
mucosa-associated lymphoid tissue lymphoma 7 | 480
progressive supranuclear palsy 7 | 674

Tissue

Digestive Tract 178 | 18,473
Female tissues 178 | 18,647
Nervous System 178 | 18,561
Endocrine System 177 | 18,512
Liver and Pancreas 177 | 18,136
Male tissues 176 | 17,969
Skin and soft tissues 176 | 18,115
Urinary Tract 176 | 18,444
Blood and immune system 174 | 17,995
Respiratory system 174 | 17,484
Cardiovascular System 173 | 17,958

Target Family

Non-IDG 82 | 11,969
Transcription Factor 37 | 1,400
Enzyme 34 | 4,146
Kinase 11 | 634
Epigenetic 6 | 242
Transporter 4 | 473
GPCR 2 | 408
Nuclear Receptor 2 | 48

GO Process

in utero embryonic development 178 | 178
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protein BRICK1 BRK1 Tbio Non-IDG -1.42109 29.2 53
Protein TANC2 TANC2 Tdark Non-IDG -1.39916 23.8 17
Pygopus homolog 2 PYGO2 Tbio Epigenetic -1.22853 25.3 76
Zinc finger protein ZFPM2 ZFPM2 Tbio Transcription Factor -1.75745 57.5 78
Chromodomain-helicase-DNA-binding protein 8 CHD8 Tbio Epigenetic -1.57734 41.1 65
Band 4.1-like protein 5 EPB41L5 Tbio Non-IDG -1.29631 20.6 94
Amyloid beta A4 precursor protein-binding family A member 2 APBA2 Tbio Non-IDG -1.58931 44.9 114
Smoothened homolog SMO Tclin GPCR -1.11229 12.5 388
Transmembrane protein 100 TMEM100 Tbio Non-IDG -0.82355 7.27 72
tRNA-splicing ligase RtcB homolog RTCB Tbio Enzyme -1.71251 52.7 117