Development Level

Tbio 16 | 11,445
Tchem 5 | 1,598
Tdark 3 | 6,588

Collection

GPCR: IDG Consortium (Complete... 1 | 25

IMPC Phenotype

abnormal behavior 3 | 298
abnormal behavioral response t... 1 | 66
abnormal embryo size 1 | 220
abnormal embryo turning 1 | 31
abnormal heart looping 1 | 5
abnormal heart morphology 1 | 162
abnormal nail morphology 1 | 8
abnormal neural tube closure 1 | 46
abnormal neural tube morpholog... 1 | 12
abnormal pelvic girdle bone mo... 1 | 12
abnormal sleep behavior 1 | 70
abnormal spine curvature 1 | 9
abnormal tail movements 1 | 12
decreased body length 1 | 101
decreased circulating choleste... 1 | 93
decreased circulating creatini... 1 | 39
decreased circulating glucose ... 1 | 126
decreased circulating magnesiu... 1 | 13
decreased grip strength 1 | 116
decreased lean body mass 1 | 135
decreased mean corpuscular hem... 1 | 50
decreased total body fat amoun... 1 | 207
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
enlarged adrenal glands 1 | 3
hyperactivity 1 | 148
hypoactivity 1 | 132
increased body length 1 | 32
increased bone mineral density 1 | 72
increased lean body mass 1 | 172
increased or absent threshold ... 1 | 101
increased total body fat amoun... 1 | 134
male infertility 1 | 123
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499
thrombocytopenia 1 | 56

Disease

Carcinoma 15 | 11,493
medulloblastoma, large-cell 11 | 6,241
osteosarcoma 11 | 7,950
ovarian cancer 11 | 8,520
psoriasis 11 | 6,694
ependymoma 8 | 4,679
lung cancer 7 | 4,740
invasive ductal carcinoma 6 | 2,951
atypical teratoid / rhabdoid tumor 5 | 5,112
group 3 medulloblastoma 5 | 4,104
group 4 medulloblastoma 5 | 1,855
malignant mesothelioma 5 | 3,232
Breast cancer 4 | 3,578
Kidney cancer 4 | 2,613
interstitial cystitis 4 | 2,312
lung adenocarcinoma 4 | 2,716
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
primary Sjogren syndrome 4 | 735
tuberculosis 4 | 2,010
Cancer 3 | 2,499
Depressive disorder 3 | 409
adult high grade glioma 3 | 3,801
atypical teratoid/rhabdoid tumor 3 | 357
colon cancer 3 | 1,478
cutaneous lupus erythematosus 3 | 1,057
ductal carcinoma in situ 3 | 1,745
glioblastoma 3 | 5,792
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
lung carcinoma 3 | 2,843
non-small cell lung cancer 3 | 2,890
pituitary cancer 3 | 1,972
spina bifida 3 | 1,074
ulcerative colitis 3 | 1,819
Amyotrophic lateral sclerosis 2 | 451
Astrocytoma, Pilocytic 2 | 3,081
Atopic dermatitis 2 | 952
Autosomal recessive predisposition 2 | 1,442
Breast Neoplasms 2 | 445
Chronic Lymphocytic Leukemia 2 | 262
Decreased tendon reflex 2 | 122
Dysarthria 2 | 192
Endometriosis 2 | 540
Gaucher disease type 1 2 | 180
Hyperreflexia 2 | 209
Liver Cirrhosis, Experimental 2 | 769
Mammary Neoplasms 2 | 425
Neurodegenerative Disorders 2 | 79
Neurodegenerative disease 2 | 414
Progressive disorder 2 | 142
aldosterone-producing adenoma 2 | 665
astrocytic glioma 2 | 2,597
astrocytoma 2 | 1,146
cystic fibrosis 2 | 1,696
diabetes mellitus 2 | 1,728
glioblastoma multiforme 2 | 142
juvenile dermatomyositis 2 | 1,187
nasopharyngeal carcinoma 2 | 1,058
oligodendroglioma 2 | 2,850
subependymal giant cell astrocytoma 2 | 2,287
Apathy 1 | 16
Collapse of vertebra 1 | 14
Compression fracture of vertebral column 1 | 14
Compulsive hoarding 1 | 7
Cranial nerve palsies 1 | 11
EMG positive sharp waves 1 | 2
EMG: myopathic abnormalities 1 | 22
Echolalia 1 | 12
Excess nuchal skin 1 | 30
Facial paralysis 1 | 18
Fatty replacement of skeletal muscle 1 | 3
Foot dorsiflexor weakness 1 | 27
Foot-drop 1 | 27
Gait, Drop Foot 1 | 24
Gait, Unsteady 1 | 29
Gastroenteritis 1 | 41
Herpes simplex 1 | 18
Hypoplastic ilia 1 | 12
Hypoplastic ischia 1 | 11
Hypoplastic pubic bone 1 | 7
Inclusion body myopathy with Paget disease of bone and frontotemporal dementia 1 | 13
Irritation - emotion 1 | 68
Leri-Weill dyschondrosteosis 1 | 7
Limited shoulder movement 1 | 3
Long bone fractures 1 | 2
Metabolic Syndrome 1 | 20
Mutism 1 | 17
Neurodegenerative Diseases 1 | 38
Paraparesis 1 | 6
Posterior fossa compression syndrome 1 | 2
Reflex, Ankle, Absent 1 | 8
Restlessness 1 | 14
Reticulocytosis 1 | 20
Rimmed vacuoles on biopsy 1 | 15
Shoulder girdle weakness 1 | 10
Shoulder weakness 1 | 10
Small wings of the pelvic girdle 1 | 12
Variation in muscle fiber size 1 | 16
Xerostomia 1 | 42

Tissue

Blood and immune system 23 | 16,909
Digestive Tract 23 | 17,369
Liver and Pancreas 23 | 16,750
Endocrine System 22 | 18,159
Female tissues 22 | 17,400
Respiratory system 22 | 16,393
Skin and soft tissues 22 | 17,230
Urinary Tract 22 | 16,678
Nervous System 21 | 16,725
Male tissues 20 | 17,142
Cardiovascular System 19 | 15,192

Target Family

Non-IDG 17 | 12,091
Enzyme 5 | 4,145
GPCR 1 | 408
Ion Channel 1 | 344

GO Process

immune system process 24 | 24
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Progesterone-induced-blocking factor 1 PIBF1 Tbio Non-IDG -1.30666 21.1 209
NudC domain-containing protein 1 NUDCD1 Tbio Non-IDG -1.07695 12.4 94
Tapasin-related protein TAPBPL Tbio Non-IDG -0.79158 8.17 248
Selenoprotein K SELENOK Tbio Non-IDG -1.39537 26.6 0
CD5 antigen-like CD5L Tbio Non-IDG -1.84241 70.5 357
Intermediate conductance calcium-activated potassium channel protein 4 KCNN4 Tchem Ion Channel -2.44473 312.3 199
Run domain Beclin-1-interacting and cysteine-rich domain-containing protein RUBCN Tbio Non-IDG -1.97676 93.5 93
Indoleamine 2,3-dioxygenase 1 IDO1 Tchem Enzyme -2.62196 421.1 684
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 INPPL1 Tchem Enzyme -2.05056 144.2 215
Interleukin-31 IL31 Tbio Non-IDG -2.18563 154.1 294