Development Level

Tbio 239 | 10,625
Tchem 67 | 1,890
Tdark 65 | 7,003
Tclin 27 | 602

Collection

Eligible Kinase Proteins 2 | 134
Eligible non-olfactory GPCR Proteins 1 | 143

IMPC Term

enlarged heart 5 | 111
preweaning lethality, complete... 5 | 633
decreased circulating insulin ... 4 | 75
decreased lean body mass 4 | 195
increased circulating alkaline... 4 | 119
preweaning lethality, incomple... 4 | 260
abnormal bone structure 3 | 131
abnormal heart morphology 3 | 51
decreased T cell number 3 | 31
decreased fasted circulating g... 3 | 49
decreased grip strength 3 | 123
improved glucose tolerance 3 | 56
increased bone mineral content 3 | 92
increased bone mineral density 3 | 52
increased mean corpuscular vol... 3 | 91
abnormal bone mineralization 2 | 55
abnormal skin morphology 2 | 23
abnormal sleep behavior 2 | 63
decreased body length 2 | 108
decreased circulating choleste... 2 | 85
decreased circulating triglyce... 2 | 83
decreased erythrocyte cell num... 2 | 43
decreased hematocrit 2 | 25
decreased hemoglobin content 2 | 53
decreased monocyte cell number 2 | 28
increased circulating sodium l... 2 | 71
increased hematocrit 2 | 36
increased hemoglobin content 2 | 45
increased mean corpuscular hem... 2 | 93
limb grasping 2 | 35
thrombocytopenia 2 | 46
vertebral fusion 2 | 23
abnormal behavior 1 | 226
abnormal behavioral response t... 1 | 52
abnormal cornea morphology 1 | 24
abnormal digit morphology 1 | 13
abnormal epididymis morphology 1 | 31
abnormal eye morphology 1 | 38
abnormal forelimb morphology 1 | 2
abnormal gait 1 | 51
abnormal kidney morphology 1 | 30
abnormal liver morphology 1 | 5
abnormal lung morphology 1 | 15
abnormal response to tactile s... 1 | 16
abnormal retina morphology 1 | 100
abnormal testis morphology 1 | 30
cataract 1 | 26
decreased B cell number 1 | 30
decreased CD4-positive, alpha ... 1 | 19
decreased IgG1 level 1 | 4
decreased Ly6C high monocyte n... 1 | 18
decreased body weight 1 | 174
decreased bone mineral content 1 | 157
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 77
decreased circulating alanine ... 1 | 53
decreased circulating alkaline... 1 | 41
decreased circulating bilirubi... 1 | 14
decreased circulating creatini... 1 | 31
decreased circulating free fat... 1 | 39
decreased circulating glucose ... 1 | 121
decreased circulating iron lev... 1 | 25
decreased lymphocyte cell numb... 1 | 9
decreased neutrophil cell numb... 1 | 37
decreased rib number 1 | 59
decreased total body fat amoun... 1 | 186
embryonic lethality prior to o... 1 | 148
embryonic lethality prior to t... 1 | 187
enlarged epididymis 1 | 27
enlarged spleen 1 | 26
enlarged testis 1 | 1
hypoactivity 1 | 89
impaired glucose tolerance 1 | 52
increased B cell number 1 | 23
increased blood urea nitrogen ... 1 | 44
increased circulating HDL chol... 1 | 63
increased circulating LDL chol... 1 | 15
increased circulating glucose ... 1 | 16
increased circulating serum al... 1 | 25
increased circulating total pr... 1 | 20
increased circulating triglyce... 1 | 24
increased erythrocyte cell num... 1 | 26
increased grip strength 1 | 83
increased lean body mass 1 | 107
increased neutrophil cell numb... 1 | 15
increased or absent threshold ... 1 | 128
increased prepulse inhibition 1 | 21
increased respiratory quotient 1 | 12
prenatal lethality prior to he... 1 | 64
small testis 1 | 37
syndactyly 1 | 4
tremors 1 | 34

Disease

psoriasis 174 | 6,685
Cancer 149 | 2,346
osteosarcoma 149 | 7,933
lung cancer 148 | 4,466
ovarian cancer 136 | 8,484
interstitial cystitis 127 | 2,299
lung carcinoma 125 | 2,844
ulcerative colitis 113 | 2,087
glioblastoma 101 | 5,572
tuberculosis 93 | 1,557
cutaneous lupus erythematosus 87 | 1,056
non-small cell lung cancer 86 | 2,798
lung adenocarcinoma 83 | 2,713
medulloblastoma, large-cell 79 | 6,234
Rheumatoid Arthritis 78 | 1,160
invasive ductal carcinoma 77 | 2,950
pilocytic astrocytoma 77 | 3,086
diabetes mellitus 71 | 1,663
Hypersensitivity reaction type II disease 69 | 235
malignant mesothelioma 68 | 3,162
pancreatic cancer 67 | 2,300
Multiple Sclerosis 64 | 498
cystic fibrosis 63 | 1,665
primary Sjogren syndrome 61 | 789
subependymal giant cell astrocytoma 58 | 2,287
intraductal papillary-mucinous neoplasm (IPMN) 56 | 3,289
Asthma 55 | 349
intraductal papillary-mucinous adenoma (IPMA) 55 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 55 | 2,988
Breast cancer 54 | 3,094
posterior fossa group A ependymoma 53 | 1,511
Arthritis 49 | 248
adult high grade glioma 48 | 2,148
pediatric high grade glioma 47 | 2,712
breast carcinoma 42 | 1,614
active Crohn's disease 41 | 918
atypical teratoid / rhabdoid tumor 41 | 4,369
colon cancer 41 | 1,475
Kidney disease 40 | 396
juvenile dermatomyositis 40 | 1,189
periodontitis 39 | 269
mucosa-associated lymphoid tissue lymphoma 38 | 480
Atopic dermatitis 37 | 944
Inflammatory bowel disease 37 | 142
pituitary cancer 37 | 1,972
adrenocortical carcinoma 36 | 1,427
gastric carcinoma 36 | 832
primary pancreatic ductal adenocarcinoma 35 | 1,271
Lung disease 33 | 132
Multiple myeloma 33 | 1,327
head and neck cancer and chronic obstructive pulmonary disease 33 | 237
pancreatic ductal adenocarcinoma liver metastasis 33 | 1,795
sarcoidosis 33 | 358
Pneumonia 31 | 133
Ankylosing spondylitis 29 | 138
Dermatitis 29 | 107
Liver disease 29 | 219
esophageal adenocarcinoma 29 | 737
nasopharyngeal carcinoma 29 | 1,056
Allergic hypersensitivity disease 28 | 123
Human immunodeficiency virus infectious disease 28 | 92
Hypersensitivity 28 | 63
group 4 medulloblastoma 28 | 1,875
oligodendroglioma 28 | 2,849
chronic lymphosyte leukemia 27 | 232
ductal carcinoma in situ 26 | 1,745
hepatocellular carcinoma 26 | 532
Atherosclerosis 25 | 275
Duchenne muscular dystrophy 25 | 602
IGA Glomerulonephritis 25 | 454
astrocytoma 25 | 1,493
dermatomyositis 25 | 933
Acquired immunodeficiency syndrome 24 | 164
Obesity 24 | 616
group 3 medulloblastoma 24 | 2,254
pancreatic carcinoma 24 | 567
primitive neuroectodermal tumor 23 | 3,031
Influenza 22 | 142
Anemia 21 | 252
Crohn's disease 21 | 304
Waldenstrons macroglobulinemia 21 | 765
non-small cell lung carcinoma 21 | 413
Uveitis 20 | 103
acute myeloid leukemia 20 | 780
ependymoma 20 | 2,514
Carcinoma 19 | 2,147
Vascular disease 19 | 281
Endometriosis 18 | 535
Malaria 18 | 140
Mammary Neoplasms 18 | 410
active ulcerative colitis 18 | 477
Celiac disease 17 | 112
Drug-Induced Liver Injury 17 | 118
Eosinophilia 17 | 65
Hepatitis B 17 | 103
Juvenile rheumatoid arthritis 17 | 104
aldosterone-producing adenoma 17 | 664
inflammatory breast cancer 17 | 404
Pick disease 16 | 1,893
Prostatic Neoplasms 16 | 471

Tissue

Digestive Tract 357 | 18,473
Blood and immune system 355 | 17,995
Female tissues 352 | 18,647
Urinary Tract 352 | 18,444
Liver and Pancreas 351 | 18,136
Nervous System 351 | 18,561
Endocrine System 347 | 18,512
Skin and soft tissues 344 | 18,115
Cardiovascular System 343 | 17,958
Respiratory system 343 | 17,484
Male tissues 336 | 17,969

Target Family

Non-IDG 319 | 11,971
GPCR 29 | 406
Enzyme 26 | 4,146
Transcription Factor 14 | 1,400
Kinase 9 | 634
TF/Epigenetic 1 | 38

GO Process

immune response 398 | 398
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Immunoglobulin kappa variable 3-11 IGKV3-11 Tdark Non-IDG 0.00000 0
T-cell receptor beta chain V region CTL-L17 TCRB Tdark Non-IDG 0.00000 0
T-cell receptor alpha chain V region CTL-L17 TCRA Tdark Non-IDG 0.00000 0
HLA class I histocompatibility antigen, A-3 alpha chain HLA-A Tbio Non-IDG -3.60614 4042.7 585
Interleukin-1 beta IL1B Tclin Non-IDG -4.34333 22444.2 1345
Antileukoproteinase SLPI Tbio Enzyme -2.56514 434.2 290
T cell receptor gamma variable 3 TRGV3 Tdark Non-IDG 0.00000 0
Properdin CFP Tbio Non-IDG -3.16935 1491.5 297
V(D)J recombination-activating protein 1 RAG1 Tbio Non-IDG -3.00063 1061.1 65
Interleukin-15 IL15 Tbio Non-IDG -3.01964 1248.2 612