Development Level

Tbio 256 | 11,651
Tdark 99 | 6,593
Tchem 42 | 1,388
Tclin 29 | 612

Collection

GPCR: IDG Consortium (Complete... 3 | 25
Kinase: IDG Consortium (Target... 1 | 125
RFA-RM-18-021 1 | 328

IMPC Phenotype

decreased vertical activity 11 | 208
enlarged heart 8 | 210
preweaning lethality, complete... 6 | 979
preweaning lethality, incomple... 5 | 499
abnormal bone structure 4 | 187
abnormal heart morphology 4 | 162
decreased circulating insulin ... 4 | 76
decreased circulating triglyce... 4 | 79
increased lean body mass 4 | 172
increased mean corpuscular vol... 4 | 92
abnormal behavior 3 | 298
abnormal spleen morphology 3 | 55
cataract 3 | 92
decreased T cell number 3 | 15
embryonic lethality prior to o... 3 | 239
enlarged spleen 3 | 41
improved glucose tolerance 3 | 79
increased bone mineral content 3 | 108
increased startle reflex 3 | 112
short tibia 3 | 97
abnormal bone mineralization 2 | 38
abnormal cecum morphology 2 | 7
abnormal epididymis morphology 2 | 42
abnormal eye anterior chamber ... 2 | 9
abnormal lens morphology 2 | 81
abnormal skin morphology 2 | 50
abnormal sleep behavior 2 | 70
abnormal vertebrae morphology 2 | 18
decreased IgG1 level 2 | 8
decreased bone mineral content 2 | 151
decreased circulating amylase ... 2 | 28
decreased circulating bilirubi... 2 | 19
decreased circulating choleste... 2 | 93
decreased circulating creatini... 2 | 39
decreased circulating glucose ... 2 | 126
decreased erythrocyte cell num... 2 | 62
decreased fasted circulating g... 2 | 65
decreased heart weight 2 | 27
decreased hematocrit 2 | 46
decreased hemoglobin content 2 | 68
decreased red blood cell distr... 2 | 41
embryonic lethality prior to t... 2 | 278
enlarged epididymis 2 | 31
enlarged uterus 2 | 11
hypoactivity 2 | 132
increased bone mineral density 2 | 72
increased circulating HDL chol... 2 | 80
increased circulating alkaline... 2 | 122
increased circulating sodium l... 2 | 71
increased circulating triglyce... 2 | 42
increased eosinophil cell numb... 2 | 11
increased leukocyte cell numbe... 2 | 47
increased lymphocyte cell numb... 2 | 32
increased mean corpuscular hem... 2 | 96
limb grasping 2 | 41
male infertility 2 | 123
small superior vagus ganglion 2 | 74
thrombocytopenia 2 | 56
vertebral fusion 2 | 23
abnormal cornea morphology 1 | 31
abnormal gait 1 | 69
abnormal liver morphology 1 | 17
abnormal lung morphology 1 | 26
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal testis morphology 1 | 43
abnormal vibrissa morphology 1 | 25
decreased CD4-positive, alpha ... 1 | 7
decreased blood urea nitrogen ... 1 | 51
decreased circulating iron lev... 1 | 32
decreased grip strength 1 | 116
decreased heart left ventricle... 1 | 28
decreased heart rate 1 | 18
decreased lean body mass 1 | 135
decreased mean corpuscular hem... 1 | 31
decreased neutrophil cell numb... 1 | 42
decreased threshold for audito... 1 | 26
enlarged lymph nodes 1 | 37
female infertility 1 | 60
hydrometra 1 | 53
hyperactivity 1 | 148
impaired glucose tolerance 1 | 75
increased circulating amylase ... 1 | 25
increased circulating chloride... 1 | 41
increased circulating glucose ... 1 | 24
increased heart rate 1 | 23
increased heart weight 1 | 62
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased large unstained cell... 1 | 5
increased monocyte cell number 1 | 63
increased prepulse inhibition 1 | 32
increased total body fat amoun... 1 | 134
microphthalmia 1 | 26
prenatal lethality prior to he... 1 | 87
prolonged RR interval 1 | 8
small testis 1 | 58
small thymus 1 | 16
syndactyly 1 | 23
tremors 1 | 39

Disease

Carcinoma 179 | 11,493
psoriasis 175 | 6,694
Cancer 155 | 2,499
lung cancer 152 | 4,740
osteosarcoma 148 | 7,950
ovarian cancer 136 | 8,520
interstitial cystitis 128 | 2,312
lung carcinoma 125 | 2,843
tuberculosis 116 | 2,010
glioblastoma 108 | 5,792
ulcerative colitis 102 | 1,819
non-small cell lung cancer 88 | 2,890
cutaneous lupus erythematosus 87 | 1,057
Rheumatoid arthritis 84 | 1,191
lung adenocarcinoma 84 | 2,716
Astrocytoma, Pilocytic 79 | 3,081
adult high grade glioma 78 | 3,801
medulloblastoma, large-cell 78 | 6,241
malignant mesothelioma 77 | 3,232
diabetes mellitus 74 | 1,728
invasive ductal carcinoma 74 | 2,951
pancreatic cancer 69 | 2,398
Hypersensitivity reaction type II disease 68 | 253
Breast cancer 67 | 3,578
Multiple Sclerosis 66 | 540
subependymal giant cell astrocytoma 61 | 2,287
cystic fibrosis 60 | 1,696
Arthritis 58 | 290
ependymoma 58 | 4,679
intraductal papillary-mucinous neoplasm (IPMN) 57 | 3,291
intraductal papillary-mucinous carcinoma (IPMC) 55 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 54 | 2,955
primary Sjogren syndrome 54 | 735
atypical teratoid / rhabdoid tumor 53 | 5,112
Asthma 52 | 385
periodontitis 44 | 293
Autosomal recessive predisposition 43 | 1,442
breast carcinoma 43 | 1,638
active Crohn's disease 41 | 922
juvenile dermatomyositis 41 | 1,187
colon cancer 40 | 1,478
Kidney disease 39 | 430
group 3 medulloblastoma 39 | 4,104
Human immunodeficiency virus infectious disease 38 | 138
Inflammatory bowel disease 38 | 151
mucosa-associated lymphoid tissue lymphoma 38 | 484
pancreatic ductal adenocarcinoma liver metastasis 38 | 1,962
pituitary cancer 38 | 1,972
sarcoidosis 38 | 370
Atopic dermatitis 37 | 952
Pneumonia 37 | 174
Dermatitis 36 | 157
adrenocortical carcinoma 36 | 1,428
Multiple myeloma 35 | 1,332
Schizophrenia 35 | 1,160
active ulcerative colitis 35 | 764
Liver Cirrhosis, Experimental 34 | 769
Lung disease 33 | 142
gastric carcinoma 33 | 807
primary pancreatic ductal adenocarcinoma 33 | 1,109
Liver disease 32 | 237
head and neck cancer and chronic obstructive pulmonary disease 32 | 239
Ankylosing spondylitis 30 | 140
Kidney cancer 30 | 2,613
esophageal adenocarcinoma 30 | 737
Hypersensitivity 29 | 63
dermatomyositis 29 | 966
Anemia 28 | 365
oligodendroglioma 28 | 2,850
Allergic hypersensitivity disease 27 | 126
group 4 medulloblastoma 27 | 1,855
nasopharyngeal carcinoma 27 | 1,058
Duchenne muscular dystrophy 26 | 601
chronic lymphosyte leukemia 26 | 204
hepatocellular carcinoma 26 | 547
Atherosclerosis 25 | 291
ductal carcinoma in situ 25 | 1,745
Acquired immunodeficiency syndrome 24 | 197
Fever 24 | 138
Diarrhea 23 | 253
Influenza 23 | 142
Obesity 23 | 678
pancreatic carcinoma 23 | 562
primitive neuroectodermal tumor 23 | 3,035
astrocytoma 22 | 1,146
posterior fossa group A ependymoma 22 | 468
Arthritis, Rheumatoid 21 | 174
Systemic lupus erythematosus 21 | 194
Uveitis 21 | 103
Vasculitis 21 | 80
Crohn's disease 20 | 321
Hepatitis B 20 | 108
Juvenile rheumatoid arthritis 20 | 111
Splenomegaly 20 | 190
Waldenstrons macroglobulinemia 20 | 765
Bipolar Disorder 19 | 666
Malaria 19 | 160
Vascular disease 19 | 319
acute myeloid leukemia 19 | 783
pediatric high grade glioma 19 | 1,064

Tissue

Blood and immune system 294 | 16,909
Digestive Tract 293 | 17,369
Skin and soft tissues 293 | 17,230
Endocrine System 287 | 18,159
Female tissues 287 | 17,400
Liver and Pancreas 287 | 16,750
Male tissues 286 | 17,142
Urinary Tract 286 | 16,678
Respiratory system 284 | 16,393
Nervous System 264 | 16,725
Cardiovascular System 248 | 15,192

Target Family

Non-IDG 346 | 12,091
GPCR 29 | 408
Enzyme 27 | 4,145
Transcription Factor 14 | 1,400
Kinase 9 | 634
TF/Epigenetic 1 | 38

GO Process

immune response 426 | 426
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Interleukin-9 IL9 Tbio Non-IDG -2.50811 334.4 459
Tyrosine-protein kinase ZAP-70 ZAP70 Tchem Kinase -2.91589 798.2 1515
Leukotriene B4 receptor 1 LTB4R Tchem GPCR -2.74171 557.6 365
Thrombospondin-1 THBS1 Tbio Non-IDG -3.06622 1281.6 504
Tumor necrosis factor receptor superfamily member 4 TNFRSF4 Tbio Non-IDG -2.60147 430.2 524
C-C motif chemokine 27 CCL27 Tbio Non-IDG -2.72180 519.6 214
Sphingosine 1-phosphate receptor 4 S1PR4 Tclin GPCR -1.78966 58.4 256
Immunoglobulin superfamily member 6 IGSF6 Tbio Non-IDG -1.87882 72.2 146
NF-kappa-B essential modulator IKBKG Tbio Kinase -3.07452 1188.4 879
Semaphorin-3C SEMA3C Tbio Non-IDG -1.95299 88.1 184