Development Level

Tbio 5 | 11,445
Tdark 4 | 6,588
Tchem 2 | 1,598
Tclin 2 | 613

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal coat appearance 1 | 31
abnormal gait 1 | 69
abnormal lens morphology 1 | 81
cataract 1 | 92
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating chloride... 1 | 30
decreased circulating glucose ... 1 | 126
decreased circulating phosphat... 1 | 27
decreased circulating triglyce... 1 | 79
decreased leukocyte cell numbe... 1 | 73
decreased prepulse inhibition 1 | 82
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged heart atrium 1 | 4
increased circulating glucose ... 1 | 24
increased mean corpuscular hem... 1 | 96
increased or absent threshold ... 1 | 101
small spleen 1 | 19

Disease

psoriasis 8 | 6,694
ovarian cancer 5 | 8,520
Autosomal recessive predisposition 4 | 1,442
Breast cancer 4 | 3,578
Multiple myeloma 4 | 1,332
medulloblastoma, large-cell 4 | 6,241
osteosarcoma 4 | 7,950
Carcinoma 3 | 11,493
Dysarthria 3 | 192
Epilepsy 3 | 792
Hypertrophic Cardiomyopathy 3 | 117
Intellectual disability 3 | 1,016
Leigh disease 3 | 100
Metabolic acidosis 3 | 90
Progressive disorder 3 | 142
astrocytoma 3 | 1,146
atypical teratoid / rhabdoid tumor 3 | 5,112
cytochrome-c oxidase deficiency disease 3 | 19
Abnormal respiratory patterns 2 | 20
Acidosis, Lactic 2 | 97
Anemia 2 | 365
Blepharoptosis 2 | 231
CSF lactate increased 2 | 33
Central nervous system demyelination 2 | 28
Cerebellar Ataxia 2 | 304
Cognitive delay 2 | 608
Congenital myasthenic syndrome, acetazolamide-responsive 2 | 5
Cytochrome-c Oxidase Deficiency 2 | 17
Diabetes mellitus type 2 2 | 69
Dull intelligence 2 | 645
Dystonia 2 | 164
Dystonic disease 2 | 106
Failure to gain weight 2 | 365
Gliosis 2 | 56
Global developmental delay 2 | 608
Hepatocellular necrosis 2 | 14
Highly variable clinical phenotype 2 | 150
Highly variable phenotype and severity 2 | 150
Highly variable phenotype, even within families 2 | 150
Hyperreflexia 2 | 209
Hypertrichosis 2 | 46
Increased serum lactate 2 | 60
Infantile onset 2 | 238
Lactic acidemia 2 | 95
Leigh syndrome 2 | 28
Low intelligence 2 | 645
Mental Retardation 2 | 645
Mental and motor retardation 2 | 608
Mental deficiency 2 | 645
Mood swings 2 | 77
Motor delay 2 | 147
Muscle Spasticity 2 | 195
Muscle hypotonia 2 | 571
No development of motor milestones 2 | 147
Nystagmus 2 | 317
Ophthalmoplegia 2 | 106
Optic Atrophy 2 | 242
Pediatric failure to thrive 2 | 365
Phenotypic variability 2 | 150
Poor school performance 2 | 645
Respiratory Failure 2 | 104
Retinitis Pigmentosa 2 | 226
Rheumatoid arthritis 2 | 1,191
Seizures 2 | 596
Sensorineural Hearing Loss (disorder) 2 | 284
Strabismus 2 | 270
Treatment Refractory Type 2 Diabetes Mellitus 2 | 53
Waldenstrons macroglobulinemia 2 | 765
adult high grade glioma 2 | 3,801
ependymoma 2 | 4,679
glioblastoma 2 | 5,792
group 3 medulloblastoma 2 | 4,104
lung cancer 2 | 4,740
lung carcinoma 2 | 2,843
non-small cell lung cancer 2 | 2,890
subependymal giant cell astrocytoma 2 | 2,287
Abnormal urinary amino-acid findings 1 | 38
Alcohol dependence 1 | 107
Alcoholic Intoxication 1 | 34
Alcoholic Intoxication, Chronic 1 | 289
Aminoaciduria 1 | 38
Decreased liver function 1 | 24
Diabetes Mellitus, Experimental 1 | 108
Encephalopathies 1 | 43
Heart failure 1 | 162
Hereditary neuropathy with liability to pressure palsies 1 | 9
Hyperhomocysteinemia 1 | 37
Increased hepatocellular lipid droplets 1 | 7
Liver dysfunction, mild 1 | 24
Myocardial Infarction 1 | 151
Pancytopenia 1 | 45
Pneumonia 1 | 174
Reduced fetal movement 1 | 51
Renal Cell Carcinoma 1 | 214
Renal tubular acidosis 1 | 24
Respiratory distress 1 | 43
Retinitis pigmentosa 11 1 | 59
Tethered spinal cord syndrome 1 | 11
Typhoid fever 1 | 22
non-small cell lung carcinoma 1 | 317

Tissue

Blood and immune system 13 | 16,909
Digestive Tract 13 | 17,369
Endocrine System 13 | 18,159
Female tissues 13 | 17,400
Liver and Pancreas 13 | 16,750
Male tissues 13 | 17,142
Nervous System 13 | 16,725
Skin and soft tissues 13 | 17,230
Urinary Tract 13 | 16,678
Cardiovascular System 12 | 15,192
Respiratory system 12 | 16,393

Target Family

Enzyme 8 | 4,145
Transporter 3 | 473
Non-IDG 2 | 12,091

GO Process

hydrogen ion transmembrane tra... 13 | 13
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cytochrome c oxidase assembly protein COX15 homolog COX15 Tbio Enzyme -1.37513 23.0 104
Proton-coupled folate transporter SLC46A1 Tchem Transporter -2.23182 177.1 76
Protoheme IX farnesyltransferase, mitochondrial COX10 Tbio Enzyme -1.60266 40.9 154
Sodium/hydrogen exchanger 1 SLC9A1 Tchem Transporter -2.93178 921.2 198
Cytochrome c oxidase subunit 8C, mitochondrial COX8C Tdark Enzyme -0.21560 1.88 12
Cytochrome c oxidase subunit NDUFA4 NDUFA4 Tclin Enzyme -1.19987 14.3 97
Cytochrome c oxidase subunit 8A, mitochondrial COX8A Tbio Enzyme -2.16497 132.5 57
Sodium-driven chloride bicarbonate exchanger SLC4A10 Tbio Transporter -1.39974 27.9 12
Normal mucosa of esophagus-specific gene 1 protein C15orf48 Tdark Non-IDG -0.66009 4.60 20
Cytochrome b-c1 complex subunit 7 UQCRB Tbio Non-IDG -1.29421 22.8 112