Development Level

Tbio 43 | 11,651
Tchem 6 | 1,388
Tclin 5 | 612
Tdark 2 | 6,593

Collection

GPCR: IDG Consortium (Complete... 1 | 25

IMPC Phenotype

preweaning lethality, complete... 4 | 979
abnormal heart morphology 3 | 162
enlarged heart 3 | 210
increased neutrophil cell numb... 3 | 46
abnormal seminal vesicle morph... 2 | 114
decreased leukocyte cell numbe... 2 | 73
decreased lymphocyte cell numb... 2 | 83
embryonic lethality prior to t... 2 | 278
increased erythrocyte cell num... 2 | 39
increased leukocyte cell numbe... 2 | 47
abnormal eye morphology 1 | 68
abnormal lung morphology 1 | 26
abnormal pancreas morphology 1 | 13
abnormal retina morphology 1 | 71
abnormal vertebrae morphology 1 | 18
decreased T cell number 1 | 15
decreased bone mineral density 1 | 126
decreased circulating magnesiu... 1 | 13
decreased heart rate 1 | 18
decreased lean body mass 1 | 135
decreased threshold for audito... 1 | 26
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
impaired glucose tolerance 1 | 75
increased CD4-positive, alpha ... 1 | 4
increased cardiac muscle contr... 1 | 8
increased circulating alkaline... 1 | 122
increased circulating triglyce... 1 | 42
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased lymphocyte cell numb... 1 | 32
increased monocyte cell number 1 | 63
increased total body fat amoun... 1 | 134
prolonged RR interval 1 | 8

Disease

psoriasis 28 | 6,694
Carcinoma 24 | 11,493
lung cancer 23 | 4,740
Cancer 21 | 2,499
interstitial cystitis 20 | 2,312
glioblastoma 19 | 5,792
osteosarcoma 19 | 7,950
ovarian cancer 19 | 8,520
cutaneous lupus erythematosus 16 | 1,057
ulcerative colitis 16 | 1,819
lung carcinoma 15 | 2,843
malignant mesothelioma 15 | 3,232
Astrocytoma, Pilocytic 14 | 3,081
tuberculosis 14 | 2,010
Hypersensitivity reaction type II disease 13 | 253
Rheumatoid arthritis 13 | 1,191
invasive ductal carcinoma 13 | 2,951
Breast cancer 12 | 3,578
intraductal papillary-mucinous adenoma (IPMA) 12 | 2,955
medulloblastoma, large-cell 12 | 6,241
non-small cell lung cancer 12 | 2,890
Multiple Sclerosis 11 | 540
cystic fibrosis 11 | 1,696
adult high grade glioma 10 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,291
lung adenocarcinoma 10 | 2,716
pituitary cancer 10 | 1,972
primary Sjogren syndrome 10 | 735
ependymoma 9 | 4,679
nasopharyngeal carcinoma 9 | 1,058
Arthritis, Rheumatoid 8 | 174
Asthma 8 | 385
Diarrhea 8 | 253
Influenza 8 | 142
Pneumonia 8 | 174
Schizophrenia 8 | 1,160
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
pancreatic cancer 8 | 2,398
periodontitis 8 | 293
sarcoidosis 8 | 370
Anemia 7 | 365
Breast Neoplasms 7 | 445
Hepatitis B 7 | 108
Hepatitis C 7 | 94
Liver Cirrhosis, Experimental 7 | 769
Mammary Neoplasms 7 | 425
astrocytoma 7 | 1,146
atypical teratoid / rhabdoid tumor 7 | 5,112
diabetes mellitus 7 | 1,728
group 4 medulloblastoma 7 | 1,855
Alzheimer's disease 6 | 658
Arthritis 6 | 290
Autosomal recessive predisposition 6 | 1,442
Bipolar Disorder 6 | 666
Chemical and Drug Induced Liver Injury 6 | 195
Crohn's disease 6 | 321
Fever 6 | 138
Human immunodeficiency virus infectious disease 6 | 138
Hypertension 6 | 396
Inflammation 6 | 120
Leukopenia 6 | 72
Liver Cirrhosis 6 | 181
Lymphoma 6 | 81
Major Depressive Disorder 6 | 301
Melanoma 6 | 711
Meningitis 6 | 67
Multiple myeloma 6 | 1,332
Myocardial Infarction 6 | 151
Splenomegaly 6 | 190
Waldenstrons macroglobulinemia 6 | 765
colon cancer 6 | 1,478
ductal carcinoma in situ 6 | 1,745
oligodendroglioma 6 | 2,850
Adult T-Cell Lymphoma/Leukemia 5 | 30
Allergic hypersensitivity disease 5 | 126
Autoimmune Diseases 5 | 67
Brain Injuries 5 | 65
Carcinoma, Squamous Cell 5 | 110
Colonic Neoplasms 5 | 142
Coronary artery disease 5 | 268
Depressive disorder 5 | 409
Dermatitis 5 | 157
Encephalitis 5 | 64
Endometriosis 5 | 540
Heart disease 5 | 306
Hypersensitivity 5 | 63
Hypertensive disease 5 | 292
Inflammatory bowel disease 5 | 151
Kidney disease 5 | 430
Leukemia-Lymphoma, Adult T-Cell 5 | 30
Liver disease 5 | 237
Neuropathy 5 | 261
Renal Cell Carcinoma 5 | 214
Thrombocytopenia 5 | 197
Unipolar Depression 5 | 250
Vasculitis 5 | 80
acute myeloid leukemia 5 | 783
group 3 medulloblastoma 5 | 4,104
primitive neuroectodermal tumor 5 | 3,035
subependymal giant cell astrocytoma 5 | 2,287

Tissue

Blood and immune system 45 | 16,909
Male tissues 42 | 17,142
Digestive Tract 41 | 17,369
Endocrine System 41 | 18,159
Female tissues 40 | 17,400
Skin and soft tissues 40 | 17,230
Urinary Tract 40 | 16,678
Respiratory system 39 | 16,393
Liver and Pancreas 38 | 16,750
Nervous System 38 | 16,725
Cardiovascular System 34 | 15,192

Target Family

Non-IDG 40 | 12,091
Transcription Factor 9 | 1,400
Enzyme 4 | 4,145
GPCR 2 | 408
TF/Epigenetic 1 | 38

GO Process

humoral immune response 56 | 56
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Interleukin-6 IL6 Tclin Non-IDG -4.50976 30968.8 2075
Interferon epsilon IFNE Tbio Non-IDG -1.68928 47.2 109
Triggering receptor expressed on myeloid cells 2 TREM2 Tbio Non-IDG -2.42594 269.9 370
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2 BST1 Tbio Enzyme -1.86410 73.3 284
Autoimmune regulator AIRE Tbio TF/Epigenetic -2.96077 942.9 491
Lactotransferrin LTF Tbio Non-IDG -2.54978 349.0 918
B-cell linker protein BLNK Tbio Non-IDG -2.82834 659.4 509
Lymphocyte antigen 86 LY86 Tbio Non-IDG -2.71842 481.6 272
Interferon gamma IFNG Tbio Non-IDG -3.90985 5727.4 2248
Interferon beta IFNB1 Tbio Non-IDG -3.83887 6789.5 731