Development Level

Tbio 12 | 11,651
Tclin 7 | 612
Tchem 6 | 1,388
Tdark 2 | 6,593

IMPC Phenotype

improved glucose tolerance 2 | 79
increased bone mineral content 2 | 108
increased bone mineral density 2 | 72
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal male genitalia morpho... 1 | 3
abnormal retina morphology 1 | 71
absent startle reflex 1 | 24
decreased bone mineral content 1 | 151
decreased brain size 1 | 4
decreased circulating calcium ... 1 | 36
decreased circulating chloride... 1 | 30
decreased heart rate 1 | 18
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 50
decreased total body fat amoun... 1 | 207
fusion of vertebral arches 1 | 7
hyperactivity 1 | 148
hypoactivity 1 | 132
increased circulating HDL chol... 1 | 80
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased circulating phosphat... 1 | 26
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased red blood cell distr... 1 | 34
limb grasping 1 | 41
polysyndactyly 1 | 2
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499
prolonged RR interval 1 | 8
small heart 1 | 10
small liver 1 | 8
small lung 1 | 5
small spleen 1 | 19
small stomach 1 | 3
small testis 1 | 58
small thymus 1 | 16
vertebral transformation 1 | 12

Disease

Carcinoma 14 | 11,493
Autosomal recessive predisposition 10 | 1,442
Cancer 10 | 2,499
ovarian cancer 10 | 8,520
Obesity 9 | 678
diabetes mellitus 9 | 1,728
psoriasis 9 | 6,694
Polycystic ovary syndrome 8 | 360
osteosarcoma 8 | 7,950
Delayed bone age 7 | 136
Male infertility 7 | 206
Alcoholic Intoxication, Chronic 6 | 289
Hyperthyroidism 6 | 53
Hypogonadism 6 | 173
glioblastoma 6 | 5,792
Adenoma 5 | 167
Amenorrhea 5 | 58
Constipation 5 | 181
Female infertility 5 | 30
Hypoglycemia 5 | 152
Hypothyroidism 5 | 122
Infertility 5 | 188
Infertility, Female 5 | 28
Kidney cancer 5 | 2,613
astrocytoma 5 | 1,146
Abdomen distended 4 | 43
Abnormality of metabolism/homeostasis 4 | 134
Delayed Puberty 4 | 97
Depressive disorder 4 | 409
Dyschezia 4 | 135
Endometriosis 4 | 540
Goiter 4 | 38
Hyperglycemia 4 | 137
Hypertension 4 | 396
Infertility, Male 4 | 46
Muscle hypotonia 4 | 571
Osteoporosis 4 | 363
Short stature 4 | 531
Sparse pubic hair 4 | 31
adult high grade glioma 4 | 3,801
atypical teratoid / rhabdoid tumor 4 | 5,112
ductal carcinoma in situ 4 | 1,745
invasive ductal carcinoma 4 | 2,951
Alcoholism 3 | 45
Anorexia nervosa 3 | 80
Anovulation 3 | 21
Astrocytoma, Pilocytic 3 | 3,081
Bipolar Disorder 3 | 666
Coarse facial features 3 | 108
Congenital hypoplasia of penis 3 | 176
Congenital hypothyroidism 3 | 26
Coronary artery disease 3 | 268
Decreased fertility 3 | 33
Dry skin 3 | 75
Dull intelligence 3 | 645
Elevated gonadotropins 3 | 15
Feeding difficulties 3 | 127
Hypertensive disease 3 | 292
Hypogonadism, Isolated Hypogonadotropic 3 | 71
Hypogonadotropic hypogonadism 3 | 89
Icterus 3 | 82
Kidney disease 3 | 430
Large bregma sutures 3 | 46
Large fontanelle 3 | 46
Large, late-closing fontanelle 3 | 46
Low intelligence 3 | 645
Low serum estradiol levels 3 | 22
Macroglossia 3 | 65
Mental Depression 3 | 333
Mental Retardation 3 | 645
Mental deficiency 3 | 645
Multiple myeloma 3 | 1,332
Muscle Weakness 3 | 170
Ovarian hyperstimulation syndrome 3 | 19
Pick disease 3 | 1,894
Poor school performance 3 | 645
Premature ovarian failure 3 | 65
Primary physiologic amenorrhea 3 | 55
Sleep disturbances 3 | 37
Small testicle 3 | 75
Sparse axillary hair 3 | 28
Tachycardia 3 | 43
Thickened facial skin with coarse facial features 3 | 108
Umbilical hernia 3 | 93
Unipolar Depression 3 | 250
Wide bregma sutures 3 | 46
Xerosis 3 | 75
astrocytic glioma 3 | 2,597
breast carcinoma 3 | 1,638
colon cancer 3 | 1,478
group 3 medulloblastoma 3 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
lung adenocarcinoma 3 | 2,716
lung cancer 3 | 4,740
lung carcinoma 3 | 2,843
non-small cell lung cancer 3 | 2,890
oligodendroglioma 3 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
pituitary cancer 3 | 1,972
primitive neuroectodermal tumor 3 | 3,035

Tissue

Endocrine System 25 | 18,159
Digestive Tract 23 | 17,369
Female tissues 22 | 17,400
Skin and soft tissues 21 | 17,230
Blood and immune system 20 | 16,909
Liver and Pancreas 20 | 16,750
Nervous System 19 | 16,725
Respiratory system 19 | 16,393
Urinary Tract 19 | 16,678
Male tissues 17 | 17,142
Cardiovascular System 16 | 15,192

Target Family

Non-IDG 14 | 12,091
GPCR 5 | 408
Nuclear Receptor 3 | 48
Enzyme 2 | 4,145
Kinase 2 | 634
Epigenetic 1 | 242

GO Process

hormone-mediated signaling pat... 27 | 27
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Choriogonadotropin subunit beta variant 1 CGB1 Tdark Non-IDG -0.23045 0.00000 12
Agouti-signaling protein ASIP Tbio Non-IDG -1.78281 57.2 34
Nuclear pore glycoprotein p62 NUP62 Tbio Non-IDG -1.80390 62.5 241
Thyrotropin receptor TSHR Tclin GPCR -3.03356 1166.1 550
Adiponectin receptor protein 2 ADIPOR2 Tbio Non-IDG -2.24463 128.8 185
Serine/threonine-protein kinase LATS1 LATS1 Tbio Kinase -2.31749 179.0 253
Tyrosine-protein phosphatase non-receptor type 11 PTPN11 Tchem Enzyme -3.11032 1400.0 1077
Lutropin subunit beta LHB Tbio Non-IDG -2.74538 538.1 502
Follitropin subunit beta FSHB Tbio Non-IDG -2.18224 143.3 599
Thyrotropin subunit beta TSHB Tbio Non-IDG -2.65550 431.2 787