Development Level

Tbio 8 | 10,625
Tclin 7 | 602
Tchem 6 | 1,890

IMPC Phenotype

decreased grip strength 2 | 123
abnormal behavior 1 | 226
abnormal retina morphology 1 | 100
decreased body length 1 | 108
decreased bone mineral content 1 | 157
decreased brain size 1 | 4
decreased circulating calcium ... 1 | 33
decreased circulating chloride... 1 | 32
decreased circulating triglyce... 1 | 83
decreased lean body mass 1 | 195
decreased total body fat amoun... 1 | 186
fusion of vertebral arches 1 | 7
hyperactivity 1 | 108
increased circulating HDL chol... 1 | 63
increased circulating alkaline... 1 | 119
increased circulating choleste... 1 | 53
increased circulating creatini... 1 | 29
increased circulating phosphat... 1 | 24
increased total body fat amoun... 1 | 57
limb grasping 1 | 35
no abnormal phenotype detected 1 | 3
polysyndactyly 1 | 2
preweaning lethality, incomple... 1 | 260
short tibia 1 | 82
small heart 1 | 8
small liver 1 | 8
small lung 1 | 5
small spleen 1 | 11
small stomach 1 | 3
small thymus 1 | 11
straub tail 1 | 26
vertebral transformation 1 | 12

Disease

Cancer 9 | 2,346
ovarian cancer 9 | 8,491
Obesity 8 | 616
osteosarcoma 8 | 7,933
psoriasis 8 | 6,685
diabetes mellitus 7 | 1,663
Carcinoma 6 | 2,147
Amenorrhea 5 | 60
Hyperthyroidism 5 | 50
Metabolic syndrome X 5 | 155
astrocytoma 5 | 1,493
glioblastoma 5 | 5,572
Adenoma 4 | 165
Endometriosis 4 | 535
Hyperglycemia 4 | 120
Hypoglycemia 4 | 81
Hypogonadism 4 | 70
Hypothyroidism 4 | 89
Male infertility 4 | 170
atypical teratoid / rhabdoid tumor 4 | 4,369
ductal carcinoma in situ 4 | 1,745
invasive ductal carcinoma 4 | 2,950
Anorexia nervosa 3 | 59
Female infertility 3 | 28
Goiter 3 | 27
Infertility 3 | 163
Multiple myeloma 3 | 1,327
Ovarian hyperstimulation syndrome 3 | 15
Pick disease 3 | 1,893
Polycystic Ovary Syndrome 3 | 334
Premature ovarian failure 3 | 64
astrocytic glioma 3 | 2,241
breast carcinoma 3 | 1,614
colon cancer 3 | 1,475
ependymoma 3 | 2,514
group 4 medulloblastoma 3 | 1,875
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,289
lung adenocarcinoma 3 | 2,714
lung carcinoma 3 | 2,844
malignant mesothelioma 3 | 3,163
medulloblastoma, large-cell 3 | 6,234
non-small cell lung cancer 3 | 2,798
oligodendroglioma 3 | 2,849
pediatric high grade glioma 3 | 2,712
pilocytic astrocytoma 3 | 3,086
primitive neuroectodermal tumor 3 | 3,031
46 XX gonadal dysgenesis 2 | 5
46, XY Disorders of Sex Development 2 | 3
Acquired metabolic disease 2 | 267
Adrenal cortical adenoma 2 | 10
Androgen insensitivity syndrome 2 | 11
Anovulation 2 | 20
Atherosclerosis 2 | 275
Cerebrovascular disease 2 | 231
Cocaine-Related Disorders 2 | 88
Congenital adrenal hyperplasia 2 | 74
Congenital hypothyroidism 2 | 20
Constipation 2 | 43
Coronary artery disease 2 | 240
Cryptorchidism 2 | 67
Cushing's syndrome 2 | 47
Down syndrome 2 | 548
Dyspepsia 2 | 34
Fatty liver disease 2 | 86
Gastritis 2 | 44
Gastroparesis 2 | 20
Gonadal Dysgenesis, 46,XX 2 | 4
Heart failure 2 | 80
Hyperinsulinism 2 | 63
Hypertension 2 | 293
Hypertensive disease 2 | 193
Hypospadias 2 | 65
Ileus 2 | 11
Kidney disease 2 | 397
Klinefelter's syndrome 2 | 59
Leydig cell tumor 2 | 9
Osteoporosis 2 | 259
Prader-Willi syndrome 2 | 45
Pseudohermaphroditism 2 | 16
Pure Gonadal Dysgenesis, 46, XX 2 | 4
Seizures 2 | 95
Thyroiditis 2 | 25
Thyrotoxicosis 2 | 38
acute myeloid leukemia 2 | 785
adrenocortical carcinoma 2 | 1,427
adult high grade glioma 2 | 2,148
dermatomyositis 2 | 966
group 3 medulloblastoma 2 | 2,254
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,988
lung cancer 2 | 4,473
non primary Sjogren syndrome sicca 2 | 840
pancreatic cancer 2 | 2,300
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,795
primary pancreatic ductal adenocarcinoma 2 | 1,271
sonic hedgehog group medulloblastoma 2 | 1,482
spina bifida 2 | 1,064
subependymal giant cell astrocytoma 2 | 2,287
ulcerative colitis 2 | 2,087
Hyperthyroxinemia 1 | 9
Juvenile xanthogranuloma 1 | 6

Tissue

Blood and immune system 21 | 17,994
Cardiovascular System 21 | 17,957
Digestive Tract 21 | 18,472
Endocrine System 21 | 18,511
Female tissues 21 | 18,646
Liver and Pancreas 21 | 18,135
Nervous System 21 | 18,560
Respiratory system 21 | 17,483
Skin and soft tissues 21 | 18,114
Urinary Tract 21 | 18,443
Male tissues 20 | 17,968

Target Family

Non-IDG 8 | 11,969
GPCR 5 | 408
Nuclear Receptor 3 | 48
Enzyme 2 | 4,146
Kinase 2 | 634
Epigenetic 1 | 242

GO Process

hormone-mediated signaling pat... 21 | 21
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 367 | 367
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
chemical synaptic transmission 238 | 238
MAPK cascade 237 | 237
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 199 | 199
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 180 | 180
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 175 | 175
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
protein folding 162 | 162
negative regulation of canonic... 161 | 161
response to lipopolysaccharide 161 | 161
T cell receptor signaling path... 160 | 160
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2-M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
type I interferon signaling pa... 130 | 130
endocytosis 129 | 129

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Agouti-signaling protein ASIP Tbio Non-IDG -1.73744 52.4 27
Adiponectin receptor protein 1 ADIPOR1 Tbio Non-IDG -2.34055 184.6 264
Renin REN Tclin Enzyme -4.52710 31987.6 454
Tyrosine-protein phosphatase non-receptor type 11 PTPN11 Tchem Enzyme -3.08398 1308.8 971
Corticotropin-releasing factor-binding protein CRHBP Tbio Non-IDG -1.98534 105.0 112
Agouti-related protein AGRP Tbio Non-IDG -2.65686 471.4 168
Glucagon receptor GCGR Tclin GPCR -2.23707 149.5 300
Thyroid hormone receptor alpha THRA Tclin Nuclear Receptor -2.71513 522.9 424
Growth hormone secretagogue receptor type 1 GHSR Tclin GPCR -2.68189 324.5 161
Lutropin-choriogonadotropic hormone receptor LHCGR Tclin GPCR -2.55746 355.6 134