Development Level

Tbio 8 | 11,445
Tclin 3 | 613
Tchem 1 | 1,598

IMPC Phenotype

hypoactivity 2 | 132
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal eye morphology 1 | 68
abnormal male genitalia morpho... 1 | 3
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal vibrissa morphology 1 | 25
abnormal vocalization 1 | 21
absent external male genitalia 1 | 1
cataract 1 | 92
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating phosphat... 1 | 27
decreased heart weight 1 | 27
decreased lean body mass 1 | 135
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased fasted circulating g... 1 | 76
increased total body fat amoun... 1 | 134
oligodactyly 1 | 1
polydactyly 1 | 7
preweaning lethality, complete... 1 | 979
small kidney 1 | 16

Disease

Carcinoma 8 | 11,493
Hypothyroidism 7 | 122
psoriasis 6 | 6,694
Autosomal recessive predisposition 5 | 1,442
Hyperthyroidism 5 | 53
Fatigue 4 | 182
Kidney cancer 4 | 2,613
Short stature 4 | 531
adrenocortical carcinoma 4 | 1,428
ependymoma 4 | 4,679
lung adenocarcinoma 4 | 2,716
Abdomen distended 3 | 43
Autism Spectrum Disorders 3 | 75
Autism spectrum disorder 3 | 101
Breast cancer 3 | 3,578
Coarse facial features 3 | 108
Cognitive delay 3 | 608
Congenital hypothyroidism 3 | 26
Constipation 3 | 181
Dull intelligence 3 | 645
Dyschezia 3 | 135
Global developmental delay 3 | 608
Goiter 3 | 38
Hypersomnia 3 | 8
Hypertension 3 | 396
Icterus 3 | 82
Intellectual disability 3 | 1,016
Large bregma sutures 3 | 46
Large fontanelle 3 | 46
Large, late-closing fontanelle 3 | 46
Low intelligence 3 | 645
Macroglossia 3 | 65
Mental Retardation 3 | 645
Mental and motor retardation 3 | 608
Mental deficiency 3 | 645
Muscle hypotonia 3 | 571
Poor school performance 3 | 645
Schizophrenia 3 | 1,160
Thickened facial skin with coarse facial features 3 | 108
Thyroid Dyshormonogenesis 1 3 | 6
Thyrotoxicosis 3 | 38
Umbilical hernia 3 | 93
Wide bregma sutures 3 | 46
diabetes mellitus 3 | 1,728
interstitial cystitis 3 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
lung carcinoma 3 | 2,843
malignant mesothelioma 3 | 3,232
nasopharyngeal carcinoma 3 | 1,058
pancreatic cancer 3 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
Addison's disease 2 | 31
Adenoma 2 | 167
Astrocytoma, Pilocytic 2 | 3,081
Atherosclerosis 2 | 291
Autoimmune Diseases 2 | 67
Autoimmune thyroiditis 2 | 27
Bipolar Disorder 2 | 666
Breast Neoplasms 2 | 445
Cancer 2 | 2,499
Celiac disease 2 | 116
Chronic granulomatous disease 2 | 13
Congenital adrenal hyperplasia 2 | 73
Electrocardiogram abnormal 2 | 81
Endometriosis 2 | 540
Essential Hypertension 2 | 94
Graves' disease 2 | 24
Gynecomastia 2 | 64
Hypogonadism 2 | 173
Kidney disease 2 | 430
Liver Cirrhosis, Experimental 2 | 769
Liver carcinoma 2 | 240
Mammary Neoplasms 2 | 425
Osteoporosis 2 | 363
Pendred Syndrome 2 | 22
Skin cancer 2 | 469
Thyroid Diseases 2 | 24
Thyroiditis 2 | 29
Thyrotoxic crisis 2 | 2
adult high grade glioma 2 | 3,801
astrocytic glioma 2 | 2,597
atypical teratoid / rhabdoid tumor 2 | 5,112
breast carcinoma 2 | 1,638
fibroadenoma 2 | 559
glioblastoma 2 | 5,792
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
lung cancer 2 | 4,740
non-small cell lung cancer 2 | 2,890
oligodendroglioma 2 | 2,850
osteosarcoma 2 | 7,950
ovarian cancer 2 | 8,520
ulcerative colitis 2 | 1,819
urothelial carcinoma 2 | 318
Aortic root dilatation 1 | 11
Arthropathy 1 | 43
Atrophy of testis 1 | 14
Coccidioidomycosis 1 | 8
Decreased plasma renin activity 1 | 9
Sparse axillary hair 1 | 28

Tissue

Blood and immune system 12 | 16,909
Digestive Tract 12 | 17,369
Endocrine System 12 | 18,159
Female tissues 12 | 17,400
Liver and Pancreas 12 | 16,750
Male tissues 12 | 17,142
Nervous System 12 | 16,725
Skin and soft tissues 12 | 17,230
Urinary Tract 12 | 16,678
Respiratory system 11 | 16,393
Cardiovascular System 9 | 15,192

Target Family

Enzyme 9 | 4,145
Non-IDG 3 | 12,091

GO Process

hormone biosynthetic process 12 | 12
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Type I iodothyronine deiodinase DIO1 Tclin Enzyme -2.19858 153.3 82
Thyroglobulin TG Tbio Non-IDG -3.88676 7423.9 1081
Steroid 17-alpha-hydroxylase/17,20 lyase CYP17A1 Tclin Enzyme -3.09734 1226.2 369
Thyroxine 5-deiodinase DIO3 Tbio Enzyme -2.21985 98.0 199
Adrenodoxin, mitochondrial FDX1 Tbio Non-IDG -2.81884 673.3 46
Type II iodothyronine deiodinase DIO2 Tbio Enzyme -2.60036 368.6 134
Thyroid peroxidase TPO Tclin Enzyme -2.83776 580.4 368
Dual oxidase 1 DUOX1 Tbio Enzyme -2.50131 279.5 85
Dual oxidase 2 DUOX2 Tchem Enzyme -2.45061 251.8 126
Hereditary hemochromatosis protein HFE Tbio Non-IDG -3.32815 2229.5 248