Development Level

Tbio 2 | 11,445
Tchem 2 | 1,598
Tclin 2 | 613

IMPC Phenotype

decreased erythrocyte cell num... 1 | 62

Disease

Carcinoma 6 | 11,493
Atherosclerosis 4 | 291
Autosomal recessive predisposition 4 | 1,442
ovarian cancer 4 | 8,520
Cancer 3 | 2,499
Cognitive delay 3 | 608
Dull intelligence 3 | 645
Epilepsy 3 | 792
Global developmental delay 3 | 608
Homocystinuria 3 | 21
Hypertension 3 | 396
Intellectual disability 3 | 1,016
Kidney disease 3 | 430
Low intelligence 3 | 645
Mental Retardation 3 | 645
Mental and motor retardation 3 | 608
Mental deficiency 3 | 645
Poor school performance 3 | 645
Seizures 3 | 596
atypical teratoid / rhabdoid tumor 3 | 5,112
glioblastoma 3 | 5,792
medulloblastoma, large-cell 3 | 6,241
osteosarcoma 3 | 7,950
Bipolar Disorder 2 | 666
Brain Ischemia 2 | 110
Breast cancer 2 | 3,578
Cardiovascular Diseases 2 | 59
Cerebrovascular accident 2 | 63
Cerebrovascular disease 2 | 238
Chemical and Drug Induced Liver Injury 2 | 195
Colonic Neoplasms 2 | 142
Comatose 2 | 56
Dementia 2 | 175
Depressive disorder 2 | 409
Down syndrome 2 | 499
Dystonia 2 | 164
Failure to gain weight 2 | 365
Hyperammonemia 2 | 30
Hyperhomocysteinemia 2 | 37
Kidney cancer 2 | 2,613
Lethargy 2 | 77
Leukopenia 2 | 72
Liver Cirrhosis, Experimental 2 | 769
Liver cancer 2 | 604
Lymphoma, Non-Hodgkin 2 | 24
Malnutrition 2 | 11
Melanoma 2 | 711
Muscle hypotonia 2 | 571
Pancreatitis 2 | 123
Pediatric failure to thrive 2 | 365
Pulmonary embolism 2 | 55
Schizophrenia 2 | 1,160
Thrombocytopenia 2 | 197
Venous Thrombosis 2 | 47
Vitamin B12 deficiency 2 | 20
Vomiting 2 | 116
adult high grade glioma 2 | 3,801
cystic fibrosis 2 | 1,696
diabetes mellitus 2 | 1,728
ependymoma 2 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
invasive ductal carcinoma 2 | 2,951
lung cancer 2 | 4,740
non-small cell lung cancer 2 | 2,890
pancreatic cancer 2 | 2,398
primary pancreatic ductal adenocarcinoma 2 | 1,109
psoriasis 2 | 6,694
spina bifida 2 | 1,074
Abnormal urinary amino-acid findings 1 | 38
Aminoaciduria 1 | 38
Anorexia 1 | 43
Aphasia 1 | 26
Apraxia 1 | 26
Argininosuccinic aciduria 1 | 17
Cerebral Ischemia 1 | 37
Chronic kidney disease stage 5 1 | 31
Citrullinemia 1 | 14
Congenital arteriovenous malformation 1 | 8
Dehydration 1 | 40
Ectopia Lentis 1 | 17
Embolism and Thrombosis 1 | 6
Hyperargininemia 1 | 8
Hyperglycemia 1 | 137
Hyperkyphosis 1 | 111
Hypermethioninemia 1 | 11
Infection of bone 1 | 19
Irritation - emotion 1 | 68
Kidney Failure, Chronic 1 | 46
Kyphosis deformity of spine 1 | 114
Methylmalonic aciduria 1 | 9
Mitral Valve Prolapse Syndrome 1 | 39
Nephritis, Tubulointerstitial 1 | 8
Precancerous Conditions 1 | 80
Pulmonary Fibrosis 1 | 106
Pyelonephritis 1 | 13
Sparse scalp hair 1 | 42
Steatohepatitis 1 | 44
Systemic primary carnitine deficiency disease 1 | 15
Thromboembolism 1 | 15
Tinea manuum 1 | 4

Tissue

Blood and immune system 6 | 16,909
Cardiovascular System 6 | 15,192
Digestive Tract 6 | 17,369
Endocrine System 6 | 18,159
Female tissues 6 | 17,400
Liver and Pancreas 6 | 16,750
Male tissues 6 | 17,142
Nervous System 6 | 16,725
Respiratory system 6 | 16,393
Skin and soft tissues 6 | 17,230
Urinary Tract 6 | 16,678

Target Family

Enzyme 6 | 4,145

GO Process

homocysteine metabolic process 6 | 6
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Methylenetetrahydrofolate reductase MTHFR Tbio Enzyme -3.68447 5032.2 275
Methylmalonyl-CoA mutase, mitochondrial MUT Tbio Enzyme -2.51690 305.3 99
Carbamoyl-phosphate synthase [ammonia], mitochondrial CPS1 Tclin Enzyme -2.28267 188.9 238
Cystathionine beta-synthase CBS Tchem Enzyme -3.25635 3246.1 391
Dipeptidase 1 DPEP1 Tclin Enzyme -2.47338 295.7 145
NADPH oxidase 4 NOX4 Tchem Enzyme -2.87113 773.1 393