Development Level

Tchem 9 | 1,598
Tbio 6 | 11,445

IMPC Phenotype

preweaning lethality, complete... 5 | 979
preweaning lethality, incomple... 3 | 499
abnormal behavior 2 | 298
increased startle reflex 2 | 112
abnormal bone structure 1 | 187
abnormal iris morphology 1 | 13
abnormal optic disc morphology 1 | 10
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal rib morphology 1 | 10
abnormal vitreous body morphol... 1 | 10
corneal opacity 1 | 32
decreased blood urea nitrogen ... 1 | 51
decreased circulating serum al... 1 | 82
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased heart left ventricle... 1 | 28
decreased lean body mass 1 | 135
decreased neutrophil cell numb... 1 | 42
decreased prepulse inhibition 1 | 82
decreased threshold for audito... 1 | 26
decreased total body fat amoun... 1 | 207
embryonic lethality prior to t... 1 | 278
hemorrhage 1 | 23
hyperactivity 1 | 148
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
impaired pupillary reflex 1 | 26
increased body length 1 | 32
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating creatini... 1 | 38
increased circulating triglyce... 1 | 42
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased mean platelet volume 1 | 45
increased neutrophil cell numb... 1 | 46
irregularly shaped pupil 1 | 7
male infertility 1 | 123
persistence of hyaloid vascula... 1 | 33
small spleen 1 | 19
tremors 1 | 39
trunk curl 1 | 16

Disease

Carcinoma 13 | 11,493
ovarian cancer 11 | 8,520
osteosarcoma 10 | 7,950
medulloblastoma, large-cell 9 | 6,241
Cancer 8 | 2,499
atypical teratoid / rhabdoid tumor 8 | 5,112
primitive neuroectodermal tumor 6 | 3,035
Intellectual disability 5 | 1,016
adult high grade glioma 5 | 3,801
ependymoma 5 | 4,679
glioblastoma 5 | 5,792
psoriasis 5 | 6,694
Astrocytoma, Pilocytic 4 | 3,081
Breast cancer 4 | 3,578
astrocytic glioma 4 | 2,597
group 3 medulloblastoma 4 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
lung cancer 4 | 4,740
non-small cell lung cancer 4 | 2,890
Autistic Disorder 3 | 364
Cocaine-Related Disorders 3 | 92
Kidney cancer 3 | 2,613
Leukemia, Myelocytic, Acute 3 | 120
Pick disease 3 | 1,894
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
malignant mesothelioma 3 | 3,232
medulloblastoma 3 | 720
oligodendroglioma 3 | 2,850
Abnormality of the fingernails 2 | 51
Acquired scoliosis 2 | 281
Alzheimer's disease 2 | 658
Big calvaria 2 | 147
Cognitive delay 2 | 608
Concave bridge of nose 2 | 195
Congenital Epicanthus 2 | 177
Congenital pes cavus 2 | 88
Cryptorchidism 2 | 296
Curvature of spine 2 | 282
Delayed speech and language development 2 | 112
Depressed nasal bridge 2 | 195
Depressed nasal root/bridge 2 | 195
Disease Models, Animal 2 | 155
Dull intelligence 2 | 645
Epilepsy 2 | 792
Feeding difficulties in infancy 2 | 175
Fine hair 2 | 42
Flexion contracture of proximal interphalangeal joint 2 | 75
Global developmental delay 2 | 608
Hyperkyphosis 2 | 111
Hypoplastic mandible condyle 2 | 275
Immune system cancer 2 | 140
Increased head circumference 2 | 147
Increased size of cranium 2 | 147
Increased size of skull 2 | 147
Kleefstra syndrome 2 | 12
Kyphosis deformity of spine 2 | 114
Language Delay 2 | 112
Large auricle 2 | 87
Large dysplastic ears 2 | 87
Large pinnae 2 | 87
Large prominent ears 2 | 87
Large protruding ears 2 | 87
Large, floppy ears 2 | 87
Learning disability 2 | 17
Long philtrum 2 | 137
Low intelligence 2 | 645
Macrotia 2 | 87
Mandibular hypoplasia 2 | 275
Mental Retardation 2 | 645
Mental and motor retardation 2 | 608
Mental deficiency 2 | 645
Microcephaly 2 | 166
Micrognathism 2 | 275
Muscle Spasticity 2 | 195
Muscle hypotonia 2 | 571
Poor school performance 2 | 645
Rheumatoid arthritis 2 | 1,191
Scoliosis 2 | 44
Seizures 2 | 596
Sotos syndrome 2 | 13
Speech Delay 2 | 112
Speech impairment 2 | 112
Weaver syndrome 2 | 7
Wolf-Hirschhorn syndrome 2 | 32
group 4 medulloblastoma 2 | 1,855
interstitial cystitis 2 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
juvenile dermatomyositis 2 | 1,187
non primary Sjogren syndrome sicca 2 | 891
subependymal giant cell astrocytoma 2 | 2,287
Anxiety Disorders 1 | 38
Citrullinemia 1 | 14
Decreased projection of midface 1 | 105
Dyslexia 1 | 43
Hoarseness 1 | 31
Hypotrophic midface 1 | 105
Muscle Rigidity 1 | 49
Progressive mental retardation 1 | 37
Short ribs 1 | 30
Sotos' syndrome 1 | 3

Tissue

Cardiovascular System 15 | 15,192
Endocrine System 15 | 18,159
Female tissues 15 | 17,400
Liver and Pancreas 15 | 16,750
Nervous System 15 | 16,725
Respiratory system 15 | 16,393
Urinary Tract 15 | 16,678
Blood and immune system 14 | 16,909
Digestive Tract 14 | 17,369
Male tissues 14 | 17,142
Skin and soft tissues 14 | 17,230

Target Family

Epigenetic 11 | 242
Transcription Factor 3 | 1,400
Enzyme 1 | 4,145

GO Process

histone methylation 15 | 15
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Histone-arginine methyltransferase CARM1 CARM1 Tchem Epigenetic -2.04034 130.8 476
Protein arginine N-methyltransferase 7 PRMT7 Tchem Epigenetic -1.32370 24.3 163
Histone-lysine N-methyltransferase NSD3 NSD3 Tbio Epigenetic -1.36629 23.0 234
N-terminal Xaa-Pro-Lys N-methyltransferase 1 NTMT1 Tbio Enzyme -1.08039 12.3 89
Transcriptional repressor CTCFL CTCFL Tbio Transcription Factor -1.80632 44.8 164
Histone-lysine N-methyltransferase EHMT2 EHMT2 Tchem Epigenetic -2.49970 327.4 277
Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific NSD1 Tbio Epigenetic -2.16239 142.5 123
Protein arginine N-methyltransferase 1 PRMT1 Tchem Epigenetic -2.35804 229.5 394
DNA-binding protein SATB1 SATB1 Tbio Transcription Factor -2.28849 219.7 322
Methyl-CpG-binding protein 2 MECP2 Tchem Transcription Factor -3.26513 1878.2 658