Development Level

Tbio 7 | 10,625
Tchem 7 | 1,890

IMPC Term

preweaning lethality, complete... 3 | 633
abnormal behavior 1 | 226
abnormal bone structure 1 | 131
abnormal rib morphology 1 | 28
abnormal vitreous body morphol... 1 | 7
corneal opacity 1 | 25
decreased circulating serum al... 1 | 79
decreased erythrocyte cell num... 1 | 43
decreased lean body mass 1 | 195
decreased total body fat amoun... 1 | 186
hyperactivity 1 | 108
hypoactivity 1 | 89
increased body weight 1 | 42
increased bone mineral content 1 | 92
increased bone mineral density 1 | 52
increased circulating creatini... 1 | 29
increased grip strength 1 | 83
increased lean body mass 1 | 107
increased mean platelet volume 1 | 19
increased neutrophil cell numb... 1 | 15
increased sacral vertebrae num... 1 | 62
oligodactyly 1 | 14
preweaning lethality, incomple... 1 | 260

Disease

ovarian cancer 10 | 8,484
osteosarcoma 9 | 7,933
medulloblastoma, large-cell 8 | 6,234
Cancer 7 | 2,346
atypical teratoid / rhabdoid tumor 6 | 4,369
primitive neuroectodermal tumor 5 | 3,031
Intellectual disability 4 | 573
glioblastoma 4 | 5,572
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,956
psoriasis 4 | 6,685
Autistic Disorder 3 | 320
Breast cancer 3 | 3,094
Pick disease 3 | 1,893
Rheumatoid Arthritis 3 | 1,160
adult high grade glioma 3 | 2,148
astrocytic glioma 3 | 2,241
ependymoma 3 | 2,514
lung cancer 3 | 4,466
medulloblastoma 3 | 1,524
non-small cell lung cancer 3 | 2,798
pilocytic astrocytoma 3 | 3,086
Alzheimer's disease 2 | 644
Carcinoma 2 | 2,147
Cocaine-Related Disorders 2 | 88
Kleefstra syndrome 2 | 9
Learning disability 2 | 20
Leukemia, Myelocytic, Acute 2 | 113
Microcephaly 2 | 149
Sotos syndrome 2 | 13
Wolf-Hirschhorn syndrome 2 | 32
group 3 medulloblastoma 2 | 2,254
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,988
juvenile dermatomyositis 2 | 1,189
malignant mesothelioma 2 | 3,162
non primary Sjogren syndrome sicca 2 | 840
oligodendroglioma 2 | 2,849
pediatric high grade glioma 2 | 2,712
sonic hedgehog group medulloblastoma 2 | 1,482
subependymal giant cell astrocytoma 2 | 2,287
Acquired immunodeficiency syndrome 1 | 164
Adenoid Cystic Carcinoma 1 | 99
Angelman syndrome 1 | 38
Anxiety Disorders 1 | 37
Apraxia 1 | 25
Attention deficit hyperactivity disorder 1 | 156
Azoospermia 1 | 89
Bowen-Conradi syndrome 1 | 16
Bruxism 1 | 19
Child Development Disorders, Pervasive 1 | 55
Congenital heart disease 1 | 63
Craniofacial Abnormalities 1 | 147
Developmental Disabilities 1 | 20
Dyslexia 1 | 36
Epilepsy 1 | 346
Ewing sarcoma 1 | 26
Fragile X syndrome 1 | 31
Hepatitis B, Chronic 1 | 15
Idiopathic Membranous Glomerulonephritis 1 | 18
Infertility 1 | 163
Learning Disorders 1 | 27
Lung Neoplasms 1 | 171
Marshall-Smith syndrome 1 | 5
Mental depression 1 | 58
Muscle hypotonia 1 | 6
Myoclonus 1 | 1
Neoplasm Metastasis 1 | 138
PITT-HOPKINS SYNDROME 1 | 21
Psychomotor Disorders 1 | 7
Pulmonary Fibrosis 1 | 66
Respiratory Insufficiency 1 | 11
Rett Syndrome, Atypical 1 | 2
Rett syndrome 1 | 18
Schizophrenia 1 | 501
Scoliosis 1 | 40
Seizures 1 | 95
Sotos' syndrome 1 | 3
Syndromic intellectual disability 1 | 9
Waldenstrons macroglobulinemia 1 | 765
Weaver syndrome 1 | 6
acute myeloid leukemia 1 | 780
acute quadriplegic myopathy 1 | 1,157
astrocytoma 1 | 1,493
atypical teratoid/rhabdoid tumor 1 | 1,095
chronic lymphosyte leukemia 1 | 232
colon cancer 1 | 1,475
cystic fibrosis 1 | 1,665
dermatomyositis 1 | 933
diabetes mellitus 1 | 1,663
hepatocellular carcinoma 1 | 532
interstitial cystitis 1 | 2,299
intraductal papillary-mucinous neoplasm (IPMN) 1 | 3,289
lung carcinoma 1 | 2,844
multidrug-resistant tuberculosis 1 | 7
pancreatic ductal adenocarcinoma liver metastasis 1 | 1,795
pituitary cancer 1 | 1,972
posterior fossa group A ependymoma 1 | 1,511
primary pancreatic ductal adenocarcinoma 1 | 1,271
progressive supranuclear palsy 1 | 674
spina bifida 1 | 1,064
tuberculosis and treatment for 6 months 1 | 686

Tissue

Blood and immune system 14 | 17,995
Cardiovascular System 14 | 17,958
Digestive Tract 14 | 18,473
Endocrine System 14 | 18,512
Female tissues 14 | 18,647
Liver and Pancreas 14 | 18,136
Male tissues 14 | 17,969
Nervous System 14 | 18,561
Respiratory system 14 | 17,484
Skin and soft tissues 14 | 18,115
Urinary Tract 14 | 18,444

Target Family

Epigenetic 10 | 242
Transcription Factor 3 | 1,400
Enzyme 1 | 4,146

GO Process

histone methylation 14 | 14
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Methyl-CpG-binding protein 2 MECP2 Tchem Transcription Factor -3.22710 1827.6 567
Transcriptional repressor CTCFL CTCFL Tbio Transcription Factor -1.73078 41.1 129
DNA-binding protein SATB1 SATB1 Tbio Transcription Factor -2.19863 197.9 293
N-terminal Xaa-Pro-Lys N-methyltransferase 1 NTMT1 Tbio Enzyme -0.98900 9.15 77
Protein arginine N-methyltransferase 1 PRMT1 Tchem Epigenetic -2.26827 200.5 309
Histone-lysine N-methyltransferase NSD3 NSD3 Tbio Epigenetic -1.10607 15.4 192
Protein arginine N-methyltransferase 7 PRMT7 Tbio Epigenetic -1.22678 20.4 136
Histone-arginine methyltransferase CARM1 CARM1 Tchem Epigenetic -1.98286 118.4 453
Histone-lysine N-methyltransferase EHMT1 EHMT1 Tchem Epigenetic -2.30788 208.1 374
Protein arginine N-methyltransferase 2 PRMT2 Tbio Epigenetic -1.17307 18.6 272