Development Level

Tchem 2 | 1,388
Tbio 1 | 11,651

IMPC Phenotype

abnormal behavioral response t... 1 | 66
decreased circulating choleste... 1 | 93
decreased mean corpuscular vol... 1 | 79
embryonic lethality prior to t... 1 | 278
female infertility 1 | 60
hemorrhage 1 | 23
preweaning lethality, complete... 1 | 979
sclerocornea 1 | 2

Disease

Carcinoma 3 | 11,493
Cancer 2 | 2,499
lung cancer 2 | 4,740
malignant mesothelioma 2 | 3,232
ovarian cancer 2 | 8,520
Abdominal pain, episodic 1 | 9
Abnormality of hair density 1 | 2
Abnormality of the pancreatic islet cells 1 | 4
Adrenal adenoma 1 | 4
Adrenocorticotropic hormone (ACTH) deficiency (disorder) 1 | 4
Adrenocorticotropin deficient adrenal insufficiency 1 | 4
Amnesia, Transient Global 1 | 9
Angiofibroma 1 | 7
Birthmark 1 | 35
Cafe-au-Lait Spots 1 | 37
Calcium pyrophosphate deposition disease 1 | 13
Carcinoid Tumor 1 | 2
Carney complex 1 | 25
Confetti-like hypopigmented macules 1 | 3
DOID:8600 1 | 4
Decreased circulating ACTH level 1 | 12
Decreased female libido 1 | 3
Decreased fertility in females 1 | 20
Decreased male fertility 1 | 7
Decreased visual acuity, progressive 1 | 36
Dyspareunia 1 | 12
Epithelial ovarian cancer 1 | 9
Erectile dysfunction 1 | 32
Esophagitis 1 | 35
Familial isolated hyperparathyroidism 1 | 2
Female hypogonadism syndrome 1 | 25
Fibrous skin tumor of tuberous sclerosis 1 | 18
Fluctuations in consciousness 1 | 3
Galactorrhea 1 | 5
Gastrinoma 1 | 1
Gastritis 1 | 47
Generalized osteopenia 1 | 99
Generalized osteoporosis with pathologic fractures 1 | 6
Growth hormone excess 1 | 14
Gynecomastia 1 | 64
HYPERPARATHYROIDISM 1 1 | 2
Hypercalcemia 1 | 59
Hypercalcemia, Infantile 1 | 3
Hypercalciuria 1 | 27
Hyperinsulinaemic hypoglycaemia 1 | 16
Hyperinsulinemia, fasting 1 | 7
Hyperinsulinemic hypoglycemia 1 | 17
Hyperparathyroidism, Primary 1 | 3
Hyperphagia 1 | 23
Hyperphosphaturia 1 | 21
Hyperprolactinemia 1 | 27
Hypogonadism, Isolated Hypogonadotropic 1 | 71
Hypogonadotropic hypogonadism 1 | 89
Hypoparathyroidism 1 | 41
Hypotension 1 | 82
Increased appetite (finding) 1 | 23
Increased calcium level in kidney 1 | 21
Increased circulating cortisol level 1 | 7
Increased serum parathyroid hormone 1 | 14
Insulinoma 1 | 24
Kleefstra syndrome 1 | 12
Leukemia, Myelocytic, Acute 1 | 120
Leukemia, Myeloid, Acute 1 | 105
Lipoma 1 | 32
McCune Albright syndrome 1 | 19
Multiple Endocrine Neoplasia Type 1 1 | 29
Multiple endocrine neoplasia type 2A 1 | 20
Multiple endocrine neoplasia type 2B 1 | 17
Multiple endocrine neoplasia type 4 1 | 5
Non-Functioning Pituitary Gland Neoplasm 1 | 6
Nonketotic hypoglycemia 1 | 6
Ocular hypertension 1 | 42
Osteopenia 1 | 99
Ovarian epithelial cancer 1 | 10
Pallor 1 | 40
Palpitations 1 | 18
Parathyroid Adenoma 1 | 19
Parathyroid carcinoma 1 | 7
Parathyroid hyperplasia 1 | 6
Peptic Ulcer 1 | 27
Pituitary Adenoma, Prolactin-Secreting 1 | 2
Pituitary growth hormone cell adenoma 1 | 8
Progressive visual loss 1 | 36
Prolactinoma 1 | 11
Recurrent hypoglycemia 1 | 4
Sebaceous adenoma 1 | 26
Secondary growth hormone deficiency 1 | 2
Secondary hypothyroidism 1 | 15
Subcutaneous lipomas 1 | 9
Testicular hypogonadism 1 | 21
Thyroid Diseases 1 | 24
Thyroid Gland Follicular Adenoma 1 | 9
Tuberous sclerosis 1 | 19
Urine phosphorous concentration above normal 1 | 21
Vipoma 1 | 2
Von Hippel-Lindau disease 1 | 19
Weight Gain 1 | 100
Zollinger-Ellison syndrome 1 | 18
intermittent abdominal pain 1 | 9
menstrual periods stopped for over 6 months 1 | 13

Tissue

Blood and immune system 3 | 16,909
Cardiovascular System 3 | 15,192
Digestive Tract 3 | 17,369
Endocrine System 3 | 18,159
Female tissues 3 | 17,400
Liver and Pancreas 3 | 16,750
Male tissues 3 | 17,142
Nervous System 3 | 16,725
Respiratory system 3 | 16,393
Skin and soft tissues 3 | 17,230
Urinary Tract 3 | 16,678

Target Family

Epigenetic 2 | 242
Non-IDG 1 | 12,091

GO Process

histone lysine methylation 3 | 3
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
N-lysine methyltransferase SETD6 SETD6 Tbio Epigenetic -0.79375 6.88 83
Menin MEN1 Tchem Non-IDG -3.23460 1803.0 382
Histone-lysine N-methyltransferase EHMT2 EHMT2 Tchem Epigenetic -2.49970 327.4 277