Development Level

Tbio 12 | 10,625
Tdark 2 | 7,003

IMPC Term

preweaning lethality, complete... 3 | 633
abnormal cornea morphology 1 | 24
abnormal gait 1 | 51
decreased blood urea nitrogen ... 1 | 31
decreased circulating creatini... 1 | 31
decreased circulating fructosa... 1 | 31
decreased lumbar vertebrae num... 1 | 62
decreased mean corpuscular hem... 1 | 34
decreased respiratory quotient 1 | 12
increased circulating magnesiu... 1 | 10
increased granulocyte number 1 | 8
increased mean corpuscular vol... 1 | 91
increased sacral vertebrae num... 1 | 62
prenatal lethality prior to he... 1 | 64
preweaning lethality, incomple... 1 | 260
short tibia 1 | 82

Disease

ovarian cancer 9 | 8,484
osteosarcoma 7 | 7,933
glioblastoma 6 | 5,572
atypical teratoid / rhabdoid tumor 5 | 4,369
oligodendroglioma 5 | 2,849
Spinocerebellar ataxia type 7 4 | 13
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,956
lung cancer 4 | 4,466
medulloblastoma, large-cell 4 | 6,234
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,795
Breast cancer 3 | 3,094
Gaucher disease type 1 3 | 171
Multiple myeloma 3 | 1,327
astrocytic glioma 3 | 2,241
astrocytoma 3 | 1,493
dermatomyositis 3 | 933
ependymoma 3 | 2,514
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,289
lung adenocarcinoma 3 | 2,713
malignant mesothelioma 3 | 3,162
primitive neuroectodermal tumor 3 | 3,031
Cancer 2 | 2,346
Carcinoma 2 | 2,147
Pick disease 2 | 1,893
group 3 medulloblastoma 2 | 2,254
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,988
juvenile dermatomyositis 2 | 1,189
lung carcinoma 2 | 2,844
psoriasis 2 | 6,685
sonic hedgehog group medulloblastoma 2 | 1,482
Acquired metabolic disease 1 | 267
Arsenic Poisoning 1 | 59
Ataxia, Spinocerebellar 1 | 15
Autosomal dominant cerebellar ataxia 1 | 34
Becker muscular dystrophy 1 | 187
Blindness 1 | 84
Brain infarction 1 | 17
Celiac disease 1 | 112
Cerebellar Ataxia 1 | 72
Cleidocranial dysplasia 1 | 10
Congestive heart failure 1 | 30
Degenerative polyarthritis 1 | 93
Dermatologic disorders 1 | 65
Down syndrome 1 | 548
Epidermodysplasia verruciformis 1 | 21
Gilles de la Tourette syndrome 1 | 47
Kidney cancer 1 | 118
Melanoma 1 | 261
Muscle Weakness 1 | 92
Neurodegenerative disease 1 | 383
Osteoarthritis 1 | 96
Osteoporosis 1 | 257
Polycystic Ovary Syndrome 1 | 332
Retinal Degeneration 1 | 49
Rheumatoid Arthritis 1 | 1,160
Schizophrenia 1 | 501
Solar retinopathy 1 | 3
Tooth agenesis 1 | 36
Waldenstrons macroglobulinemia 1 | 765
Warsaw breakage syndrome 1 | 12
acute myeloid leukemia 1 | 780
adrenocortical carcinoma 1 | 1,427
adult high grade glioma 1 | 2,148
aldosterone-producing adenoma 1 | 664
chronic rhinosinusitis 1 | 512
diabetes mellitus 1 | 1,663
esophageal adenocarcinoma 1 | 737
group 4 medulloblastoma 1 | 1,875
medulloblastoma 1 | 1,524
non-small cell lung cancer 1 | 2,798
pediatric high grade glioma 1 | 2,712
pituitary cancer 1 | 1,972
posterior fossa group B ependymoma 1 | 1,530
progressive supranuclear palsy 1 | 674
spina bifida 1 | 1,064
subependymal giant cell astrocytoma 1 | 2,287
tuberculosis 1 | 1,557

Tissue

Blood and immune system 14 | 17,995
Cardiovascular System 14 | 17,958
Female tissues 14 | 18,647
Male tissues 14 | 17,969
Nervous System 14 | 18,561
Digestive Tract 13 | 18,473
Endocrine System 13 | 18,512
Liver and Pancreas 13 | 18,136
Respiratory system 13 | 17,484
Skin and soft tissues 13 | 18,115
Urinary Tract 13 | 18,444

Target Family

Enzyme 7 | 4,146
Non-IDG 6 | 11,971
Epigenetic 1 | 242

GO Process

histone deubiquitination 14 | 14
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ubiquitin carboxyl-terminal hydrolase 22 USP22 Tbio Enzyme -1.59877 51.0 199
Ataxin-7 ATXN7 Tbio Non-IDG -2.31354 225.6 109
Ubiquitin carboxyl-terminal hydrolase 3 USP3 Tbio Enzyme -1.06110 12.5 218
Transcription initiation factor TFIID subunit 10 TAF10 Tbio Non-IDG -1.16545 13.4 86
Ubiquitin carboxyl-terminal hydrolase 21 USP21 Tbio Enzyme -1.62273 43.6 243
Transformation/transcription domain-associated protein TRRAP Tbio Non-IDG -1.58619 36.3 148
Ubiquitin carboxyl-terminal hydrolase 16 USP16 Tbio Enzyme -0.67521 5.64 210
Ataxin-7-like protein 3 ATXN7L3 Tdark Non-IDG -0.50326 2.82 34
Transcription initiation protein SPT3 homolog SUPT3H Tbio Non-IDG -0.68337 4.62 95
Histone acetyltransferase KAT2A KAT2A Tbio Epigenetic -2.42447 258.2 245