Development Level

Tbio 11 | 11,651
Tdark 1 | 6,593

IMPC Phenotype

preweaning lethality, complete... 4 | 979
abnormal cornea morphology 1 | 31
abnormal gait 1 | 69
decreased blood urea nitrogen ... 1 | 51
decreased circulating creatini... 1 | 39
decreased circulating fructosa... 1 | 30
decreased mean corpuscular hem... 1 | 50
decreased mean platelet volume 1 | 25
decreased total body fat amoun... 1 | 207
increased circulating magnesiu... 1 | 10
increased mean corpuscular vol... 1 | 92
prenatal lethality prior to he... 1 | 87
preweaning lethality, incomple... 1 | 499
short tibia 1 | 97

Disease

Carcinoma 8 | 11,493
ovarian cancer 8 | 8,520
osteosarcoma 6 | 7,950
Spinocerebellar ataxia type 7 4 | 13
glioblastoma 4 | 5,792
oligodendroglioma 4 | 2,850
Breast cancer 3 | 3,578
Multiple myeloma 3 | 1,332
atypical teratoid / rhabdoid tumor 3 | 5,112
group 3 medulloblastoma 3 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
lung adenocarcinoma 3 | 2,716
lung cancer 3 | 4,740
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
Cancer 2 | 2,499
Gaucher disease type 1 2 | 180
Kidney cancer 2 | 2,613
astrocytic glioma 2 | 2,597
astrocytoma 2 | 1,146
dermatomyositis 2 | 966
juvenile dermatomyositis 2 | 1,187
malignant mesothelioma 2 | 3,232
medulloblastoma, large-cell 2 | 6,241
primitive neuroectodermal tumor 2 | 3,035
Acquired metabolic disease 1 | 336
Arsenic Poisoning 1 | 62
Ataxia, Spinocerebellar 1 | 16
Attention deficit hyperactivity disorder 1 | 278
Autosomal dominant cerebellar ataxia 1 | 33
Babinski Reflex 1 | 100
Becker muscular dystrophy 1 | 191
Blindness 1 | 88
Brain infarction 1 | 22
Cerebellar Ataxia 1 | 304
Cerebellar Dysmetria 1 | 56
Chorea 1 | 29
Choreatic disease 1 | 52
Cleidocranial dysplasia 1 | 10
Congestive heart failure 1 | 113
Decreased visual acuity, progressive 1 | 36
Deglutition Disorders 1 | 132
Dermatologic disorders 1 | 93
Down syndrome 1 | 499
Endometrial cancer 1 | 311
Epidermodysplasia verruciformis 1 | 21
Extrapyramidal Disorders 1 | 29
Extrapyramidal sign 1 | 29
Gait Ataxia 1 | 51
Gilles de la Tourette syndrome 1 | 47
Immune system cancer 1 | 140
Liver cancer 1 | 604
Macular degeneration 1 | 65
Melanoma 1 | 711
Metaphyseal dysplasia with maxillary hypoplasia and brachydactyly 1 | 2
Movement Disorders 1 | 55
Muscle Spasticity 1 | 195
Neurodegenerative disease 1 | 414
Neuronal ceroid lipofuscinosis 2 1 | 17
Olivopontocerebellar Atrophies 1 | 6
Osteoarthritis 1 | 184
Osteoporosis 1 | 363
Pick disease 1 | 1,894
Pigmentary retinal degeneration 1 | 11
Progressive visual loss 1 | 36
Reflex, Abnormal 1 | 5
Retinal Degeneration 1 | 106
Retinal exudates 1 | 11
Rheumatoid arthritis 1 | 1,191
Schizophrenia 1 | 1,160
Skin Diseases 1 | 71
Skin cancer 1 | 469
Slowed saccades 1 | 12
Solar retinopathy 1 | 3
Spinocerebellar Ataxias 1 | 34
Sporotrichosis 1 | 10
Supranuclear ophthalmoplegia 1 | 4
Tooth agenesis 1 | 44
Vision Disorders 1 | 6
Warsaw breakage syndrome 1 | 11
Xeroderma pigmentosum group B 1 | 20
acute myeloid leukemia 1 | 783
adrenocortical carcinoma 1 | 1,428
aldosterone-producing adenoma 1 | 665
chronic rhinosinusitis 1 | 512
diabetes mellitus 1 | 1,728
ependymoma 1 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 1 | 2,989
lingual-facial-buccal dyskinesia 1 | 13
lung carcinoma 1 | 2,843
non-small cell lung cancer 1 | 2,890
pediatric high grade glioma 1 | 1,064
pituitary cancer 1 | 1,972
posterior fossa group B ependymoma 1 | 416
progressive supranuclear palsy 1 | 676
psoriasis 1 | 6,694
sonic hedgehog group medulloblastoma 1 | 467
spina bifida 1 | 1,074
subependymal giant cell astrocytoma 1 | 2,287
tuberculosis 1 | 2,010

Tissue

Blood and immune system 12 | 16,909
Cardiovascular System 12 | 15,192
Digestive Tract 12 | 17,369
Endocrine System 12 | 18,159
Female tissues 12 | 17,400
Liver and Pancreas 12 | 16,750
Male tissues 12 | 17,142
Nervous System 12 | 16,725
Respiratory system 12 | 16,393
Skin and soft tissues 12 | 17,230
Urinary Tract 12 | 16,678

Target Family

Non-IDG 6 | 12,091
Enzyme 5 | 4,145
Epigenetic 1 | 242

GO Process

histone deubiquitination 12 | 12
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ubiquitin carboxyl-terminal hydrolase 3 USP3 Tbio Enzyme -1.16770 14.5 246
Ubiquitin carboxyl-terminal hydrolase 16 USP16 Tbio Enzyme -0.67094 5.97 248
Transformation/transcription domain-associated protein TRRAP Tbio Non-IDG -1.62460 39.0 162
Ataxin-7-like protein 3 ATXN7L3 Tdark Non-IDG -0.47792 2.50 44
Ataxin-7 ATXN7 Tbio Non-IDG -2.33556 232.9 120
Histone acetyltransferase KAT2A KAT2A Tbio Epigenetic -2.46487 271.9 262
Transcription initiation protein SPT3 homolog SUPT3H Tbio Non-IDG -0.68418 4.62 109
Ubiquitin carboxyl-terminal hydrolase 22 USP22 Tbio Enzyme -1.68483 57.9 220
Transcription initiation factor TFIID subunit 10 TAF10 Tbio Non-IDG -1.26261 15.2 107
Ubiquitin carboxyl-terminal hydrolase 21 USP21 Tbio Enzyme -1.64460 44.9 288