Development Level

Tbio 10 | 11,445
Tchem 5 | 1,598
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 3 | 979
embryonic lethality prior to t... 2 | 278
abnormal cornea morphology 1 | 31
abnormal embryo size 1 | 220
abnormal eye morphology 1 | 68
abnormal lens morphology 1 | 81
abnormal retinal blood vessel ... 1 | 26
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
abnormal vertebral arch morpho... 1 | 9
cataract 1 | 92
decreased IgG2b level 1 | 4
decreased blood urea nitrogen ... 1 | 51
decreased body weight 1 | 161
decreased cardiac stroke volum... 1 | 6
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased lactate dehydrogenas... 1 | 16
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
increased circulating alkaline... 1 | 122
increased circulating magnesiu... 1 | 10
increased mean corpuscular vol... 1 | 92
increased respiratory quotient 1 | 2
small spleen 1 | 19
small testis 1 | 58
thrombocytopenia 1 | 56
tremors 1 | 39

Disease

osteosarcoma 13 | 7,950
Carcinoma 11 | 11,493
ovarian cancer 10 | 8,520
malignant mesothelioma 8 | 3,232
Breast cancer 6 | 3,578
group 3 medulloblastoma 6 | 4,104
psoriasis 6 | 6,694
Blepharoptosis 5 | 231
Cancer 5 | 2,499
Dull intelligence 5 | 645
Intellectual disability 5 | 1,016
Kidney cancer 5 | 2,613
Low intelligence 5 | 645
Low set ears 5 | 181
Mental Retardation 5 | 645
Mental deficiency 5 | 645
Muscle hypotonia 5 | 571
Poor school performance 5 | 645
Small head 5 | 374
astrocytoma 5 | 1,146
lung cancer 5 | 4,740
Acquired scoliosis 4 | 281
Atrial Septal Defects 4 | 85
Autistic Disorder 4 | 364
Byzanthine arch palate 4 | 194
Cognitive delay 4 | 608
Congenital Epicanthus 4 | 177
Congenital deafness 4 | 185
Cryptorchidism 4 | 296
Curvature of spine 4 | 282
Deafness 4 | 198
Delayed bone age 4 | 136
Delayed speech and language development 4 | 112
Epilepsy 4 | 792
Feeding difficulties in infancy 4 | 175
Global developmental delay 4 | 608
Hearing Loss, Partial 4 | 185
Hypoplastic mandible condyle 4 | 275
Language Delay 4 | 112
Mandibular hypoplasia 4 | 275
Mental and motor retardation 4 | 608
Micrognathism 4 | 275
Pectus excavatum 4 | 100
Schizophrenia 4 | 1,160
Seizures 4 | 596
Short stature 4 | 531
Speech Delay 4 | 112
Speech impairment 4 | 112
Strabismus 4 | 270
Ventricular Septal Defects 4 | 119
atypical teratoid / rhabdoid tumor 4 | 5,112
hearing impairment 4 | 199
medulloblastoma, large-cell 4 | 6,241
subependymal giant cell astrocytoma 4 | 2,287
Adenoid Cystic Carcinoma 3 | 99
Agenesis of corpus callosum 3 | 83
Bilateral fifth finger clinodactyly 3 | 110
Carcinoma, Adenoid Cystic 3 | 99
Cardiac Arrhythmia 3 | 103
Cardiac conduction abnormalities 3 | 78
Conduction disorder of the heart 3 | 79
Constipation 3 | 181
Curvature of little finger 3 | 110
Downward slant of palpebral fissure 3 | 158
Dyschezia 3 | 135
EKG abnormalities 3 | 78
Electrocardiogram abnormal 3 | 81
Electrocardiogram change 3 | 78
Electroencephalogram abnormal 3 | 101
Endometrial cancer 3 | 311
Exophthalmos 3 | 112
Failure to gain weight 3 | 365
Hyperreflexia 3 | 209
Immune system cancer 3 | 140
Laryngomalacia 3 | 14
Low posterior hairline 3 | 52
Microstomia 3 | 78
Patent ductus arteriosus 3 | 90
Pediatric failure to thrive 3 | 365
Penile hypospadias 3 | 106
Polyhydramnios 3 | 108
Prominent eyes 3 | 96
Prominent globes 3 | 96
Protruding eyes 3 | 96
Respiratory distress 3 | 43
Stereotyped Behavior 3 | 37
Stereotypic Movement Disorder 3 | 42
glioblastoma 3 | 5,792
primitive neuroectodermal tumor 3 | 3,035
Agoraphobia 2 | 21
Broad thumbs 2 | 28
Carcinoma, Squamous Cell 2 | 110
Decreased projection of maxilla 2 | 66
Deficiency of upper jaw bones 2 | 66
Deglutition Disorders 2 | 132
Hypotrophic maxilla 2 | 66
Maxillary retrognathia 2 | 66
Poor coordination 2 | 11
Retrusion of upper jaw bones 2 | 66
Spina bifida occulta 2 | 19

Tissue

Blood and immune system 16 | 16,909
Cardiovascular System 16 | 15,192
Digestive Tract 16 | 17,369
Endocrine System 16 | 18,159
Female tissues 16 | 17,400
Liver and Pancreas 16 | 16,750
Male tissues 16 | 17,142
Nervous System 16 | 16,725
Respiratory system 16 | 16,393
Skin and soft tissues 16 | 17,230
Urinary Tract 16 | 16,678

Target Family

Epigenetic 7 | 242
Non-IDG 5 | 12,091
Transcription Factor 3 | 1,400
Enzyme 1 | 4,145

GO Process

histone acetylation 16 | 16
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Methyl-CpG-binding domain protein 3 MBD3 Tbio Transcription Factor -0.85800 7.92 309
Carboxypeptidase A4 CPA4 Tbio Enzyme -1.69484 48.3 61
Transcription initiation factor TFIID subunit 5 TAF5 Tbio Non-IDG -1.08338 9.03 81
MRG/MORF4L-binding protein MRGBP Tbio Non-IDG -0.74186 5.72 147
Transformation/transcription domain-associated protein TRRAP Tbio Non-IDG -1.62460 39.0 162
Histone acetyltransferase KAT6B KAT6B Tbio Epigenetic -2.30232 201.0 58
Histone acetyltransferase p300 EP300 Tchem Epigenetic -3.79743 6016.7 775
Methyl-CpG-binding protein 2 MECP2 Tchem Transcription Factor -3.26513 1878.2 658
Polycomb group RING finger protein 2 PCGF2 Tbio Non-IDG -1.59185 43.8 189
Transcriptional adapter 2-beta TADA2B Tdark Transcription Factor -0.46789 2.68 52