Development Level

Tbio 12 | 11,445
Tchem 3 | 1,598

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal coat-hair pigmentatio... 1 | 64
abnormal cornea morphology 1 | 31
abnormal lens morphology 1 | 81
abnormal retinal outer nuclear... 1 | 3
cataract 1 | 92
corneal opacity 1 | 32
decreased grip strength 1 | 116
decreased hematocrit 1 | 46
decreased startle reflex 1 | 75
decreased total retina thickne... 1 | 17
embryonic lethality prior to o... 1 | 239
female infertility 1 | 60
impaired glucose tolerance 1 | 75
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased circulating sodium l... 1 | 71
irregularly shaped pupil 1 | 7
male infertility 1 | 123
mydriasis 1 | 6
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 13 | 11,493
ovarian cancer 9 | 8,520
osteosarcoma 7 | 7,950
atypical teratoid / rhabdoid tumor 6 | 5,112
glioblastoma 5 | 5,792
group 3 medulloblastoma 5 | 4,104
medulloblastoma, large-cell 5 | 6,241
ependymoma 4 | 4,679
psoriasis 4 | 6,694
Breast cancer 3 | 3,578
Cancer 3 | 2,499
Intellectual disability 3 | 1,016
Kidney cancer 3 | 2,613
invasive ductal carcinoma 3 | 2,951
malignant mesothelioma 3 | 3,232
oligodendroglioma 3 | 2,850
subependymal giant cell astrocytoma 3 | 2,287
Koolen de Vries syndrome 2 | 18
Muscle hypotonia 2 | 571
active Crohn's disease 2 | 922
acute myeloid leukemia 2 | 783
adult high grade glioma 2 | 3,801
astrocytic glioma 2 | 2,597
colon cancer 2 | 1,478
dermatomyositis 2 | 966
diabetes mellitus 2 | 1,728
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
non-small cell lung cancer 2 | 2,890
pediatric high grade glioma 2 | 1,064
primitive neuroectodermal tumor 2 | 3,035
spina bifida 2 | 1,074
Adenoid Cystic Carcinoma 1 | 99
Aicardi syndrome 1 | 14
Alzheimer's disease 1 | 658
Amyotrophic lateral sclerosis 1 | 451
Brachycephaly 1 | 88
Broad cranium shape 1 | 88
Calcific tendinitis 1 | 8
Campylobacteriosis 1 | 11
Carcinoma, Adenoid Cystic 1 | 99
Cardiomyopathy, Hypertrophic 1 | 24
Chromosome 17 deletion 1 | 2
Chronic Lymphocytic Leukemia 1 | 262
Chronic obstructive pulmonary disease 1 | 184
Colorectal Neoplasms 1 | 243
Craniofacial Abnormalities 1 | 151
Diabetes Mellitus, Type 2 1 | 142
Edwards syndrome 1 | 17
Endometrial stromal nodule 1 | 11
Endometrial stromal sarcoma 1 | 15
Failure to gain weight 1 | 365
Gastroparesis 1 | 22
Heart failure 1 | 162
Hyperglycemia 1 | 137
Hypsarrhythmia 1 | 25
Infantile onset 1 | 238
Kabuki syndrome 1 | 27
Kleefstra syndrome 1 | 12
Leukemia, Megakaryoblastic, of Down Syndrome 1 | 8
Liver cancer 1 | 604
Liver neoplasms 1 | 130
Lymphangitis 1 | 6
Lymphatic Metastasis 1 | 15
Methylmalonic acidemia 1 | 37
Methylmalonic aciduria 1 | 9
Myxoid leiomyosarcoma 1 | 3
Neonatal abstinence syndrome 1 | 11
Ossifying fibromyxoid tumor 1 | 5
Parkinson's disease 1 | 392
Pediatric failure to thrive 1 | 365
Pick disease 1 | 1,894
Pitt-Hopkins syndrome 1 | 20
Pneumonia 1 | 174
Red color blindness 1 | 4
Retinitis pigmentosa 11 1 | 59
Schizophrenia 1 | 1,160
Smooth muscle tumor 1 | 13
Von Hippel-Lindau disease 1 | 19
Wide skull shape 1 | 88
X- linked recessive 1 | 110
aldosterone-producing adenoma 1 | 665
astrocytoma 1 | 1,146
breast carcinoma 1 | 1,638
cystic fibrosis 1 | 1,696
ductal carcinoma in situ 1 | 1,745
hereditary spastic paraplegia 1 | 318
hereditary spastic paraplegia 52 1 | 2
juvenile dermatomyositis 1 | 1,187
lung adenocarcinoma 1 | 2,716
lung cancer 1 | 4,740
lung carcinoma 1 | 2,843
non diabetic and post-ischemic heart failure 1 | 200
pancreatic cancer 1 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 1 | 1,962
pituitary cancer 1 | 1,972
posterior fossa group B ependymoma 1 | 416
progressive supranuclear palsy 1 | 676
tuberculosis 1 | 2,010
ulcerative colitis 1 | 1,819

Tissue

Blood and immune system 15 | 16,909
Cardiovascular System 15 | 15,192
Digestive Tract 15 | 17,369
Endocrine System 15 | 18,159
Female tissues 15 | 17,400
Liver and Pancreas 15 | 16,750
Male tissues 15 | 17,142
Nervous System 15 | 16,725
Respiratory system 15 | 16,393
Skin and soft tissues 15 | 17,230
Urinary Tract 15 | 16,678

Target Family

Non-IDG 7 | 12,091
Epigenetic 6 | 242
Enzyme 1 | 4,145
TF/Epigenetic 1 | 38

GO Process

histone H4-K5 acetylation 15 | 15
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Inhibitor of growth protein 4 ING4 Tbio Epigenetic -1.76632 69.3 193
KAT8 regulatory NSL complex subunit 3 KANSL3 Tbio Non-IDG -2.41893 257.3 75
Protein Jade-3 JADE3 Tbio Epigenetic -0.05872 0.71 93
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit OGT Tchem Enzyme -2.98896 993.7 264
Microspherule protein 1 MCRS1 Tbio Non-IDG -1.40659 32.1 99
KAT8 regulatory NSL complex subunit 2 KANSL2 Tbio Non-IDG -0.72700 5.47 32
PHD finger protein 20 PHF20 Tbio Epigenetic -2.89181 748.7 104
Protein Jade-1 JADE1 Tbio Epigenetic -1.03359 13.3 135
KAT8 regulatory NSL complex subunit 1 KANSL1 Tbio Non-IDG -1.27149 17.9 36
WD repeat-containing protein 5 WDR5 Tchem Non-IDG -2.10077 115.4 299