Development Level

Tbio 26 | 10,625
Tchem 3 | 1,890
Tdark 1 | 7,003

IMPC Term

abnormal behavior 2 | 226
decreased body weight 2 | 174
increased mean corpuscular vol... 2 | 91
preweaning lethality, complete... 2 | 633
abnormal bone mineralization 1 | 55
abnormal coat/hair pigmentatio... 1 | 54
abnormal coping response 1 | 12
abnormal cornea morphology 1 | 24
abnormal gait 1 | 51
decreased blood urea nitrogen ... 1 | 31
decreased circulating choleste... 1 | 85
decreased circulating insulin ... 1 | 75
decreased fasted circulating g... 1 | 49
decreased leukocyte cell numbe... 1 | 54
decreased lumbar vertebrae num... 1 | 62
decreased mean corpuscular vol... 1 | 50
decreased prepulse inhibition 1 | 52
decreased respiratory quotient 1 | 12
embryonic lethality prior to o... 1 | 148
embryonic lethality prior to t... 1 | 187
increased circulating creatine... 1 | 2
increased circulating magnesiu... 1 | 10
increased granulocyte number 1 | 8
increased lactate dehydrogenas... 1 | 3
increased sacral vertebrae num... 1 | 62
increased startle reflex 1 | 38
prenatal lethality prior to he... 1 | 64

Disease

ovarian cancer 19 | 8,484
osteosarcoma 14 | 7,933
medulloblastoma, large-cell 12 | 6,234
Cancer 10 | 2,346
lung cancer 10 | 4,466
malignant mesothelioma 10 | 3,162
psoriasis 10 | 6,685
atypical teratoid / rhabdoid tumor 9 | 4,369
glioblastoma 9 | 5,572
primitive neuroectodermal tumor 9 | 3,031
Carcinoma 7 | 2,147
astrocytoma 7 | 1,493
Breast cancer 6 | 3,094
Multiple myeloma 6 | 1,327
ependymoma 6 | 2,514
oligodendroglioma 6 | 2,849
pediatric high grade glioma 6 | 2,712
Rheumatoid Arthritis 5 | 1,160
colon cancer 5 | 1,475
non-small cell lung cancer 5 | 2,798
sonic hedgehog group medulloblastoma 5 | 1,482
adult high grade glioma 4 | 2,148
group 3 medulloblastoma 4 | 2,254
hepatocellular carcinoma 4 | 532
invasive ductal carcinoma 4 | 2,950
lung adenocarcinoma 4 | 2,713
lung carcinoma 4 | 2,844
Kidney cancer 3 | 118
Mammary Neoplasms 3 | 410
Waldenstrons macroglobulinemia 3 | 765
acute myeloid leukemia 3 | 780
adrenocortical carcinoma 3 | 1,427
dermatomyositis 3 | 933
ductal carcinoma in situ 3 | 1,745
group 4 medulloblastoma 3 | 1,875
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,988
medulloblastoma 3 | 1,524
pilocytic astrocytoma 3 | 3,086
posterior fossa group A ependymoma 3 | 1,511
Adenoid Cystic Carcinoma 2 | 99
Chronic Lymphocytic Leukemia 2 | 242
Colorectal Neoplasms 2 | 217
Endometriosis 2 | 535
Melanoma 2 | 261
Neuroblastoma 2 | 78
Neurodegenerative disease 2 | 383
Peripheral Neuropathy 2 | 303
Pick disease 2 | 1,893
Prostate cancer 2 | 172
Prostatic Neoplasms 2 | 471
Schizophrenia 2 | 501
aldosterone-producing adenoma 2 | 664
breast carcinoma 2 | 1,614
diabetes mellitus 2 | 1,663
gastric cancer 2 | 430
interstitial cystitis 2 | 2,299
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,956
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,289
juvenile dermatomyositis 2 | 1,189
non primary Sjogren syndrome sicca 2 | 840
progressive supranuclear palsy 2 | 674
sarcoidosis 2 | 358
subependymal giant cell astrocytoma 2 | 2,287
ulcerative colitis 2 | 2,087
urothelial carcinoma 2 | 318
Adult T-Cell Lymphoma/Leukemia 1 | 30
Alcohol dependence 1 | 107
Benign epilepsy with centrotemporal spikes 1 | 11
Brain disease 1 | 83
Celiac disease 1 | 112
Common variable immunodeficiency 1 | 72
Creutzfeldt-Jakob disease 1 | 19
Dyslexia 1 | 36
Dysplastic nevus syndrome 1 | 7
Endometrial Neoplasms 1 | 50
Epicondylitis 1 | 19
Fanconi's anemia 1 | 50
Freckles 1 | 6
Glioma 1 | 65
Idiopathic scoliosis 1 | 29
Leukopenia 1 | 42
Lung Neoplasms 1 | 171
Lymphoma, T-Cell, Cutaneous 1 | 21
Lynch syndrome 1 | 33
Malignant neoplasm of ovary 1 | 13
Mammary Neoplasms, Experimental 1 | 150
Motor neuron disease 1 | 39
Neoplasm Metastasis 1 | 138
Neoplastic Syndromes, Hereditary 1 | 48
Pancreatic carcinoma, familial 1 | 8
Periodic limb movement disorder 1 | 6
Progressive relapsing multiple sclerosis 1 | 18
Rectal prolapse 1 | 12
Silver-Russell syndrome 1 | 37
Skin carcinoma 1 | 3
Squamous cell carcinoma of esophagus 1 | 82
Squamous cell carcinoma of the head and neck 1 | 24
Stevens-Johnson syndrome 1 | 78
interstitial lung disease 1 | 291
ovarian neoplasm 1 | 97

Tissue

Blood and immune system 29 | 17,995
Cardiovascular System 29 | 17,958
Digestive Tract 29 | 18,473
Endocrine System 29 | 18,512
Female tissues 29 | 18,647
Liver and Pancreas 29 | 18,136
Male tissues 29 | 17,969
Nervous System 29 | 18,561
Skin and soft tissues 29 | 18,115
Urinary Tract 29 | 18,444
Respiratory system 28 | 17,484

Target Family

Non-IDG 16 | 11,971
Epigenetic 8 | 242
Enzyme 3 | 4,146
Transcription Factor 3 | 1,400

GO Process

histone H4 acetylation 30 | 30
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ubiquitin carboxyl-terminal hydrolase 22 USP22 Tbio Enzyme -1.59877 51.0 199
Period circadian protein homolog 1 PER1 Tbio Non-IDG -1.79100 61.2 150
Bromodomain-containing protein 8 BRD8 Tbio Epigenetic -0.58943 5.02 106
Lymphoid enhancer-binding factor 1 LEF1 Tchem Transcription Factor -2.56120 352.4 554
Inhibitor of growth protein 3 ING3 Tbio Epigenetic -2.29256 191.2 148
Breast cancer type 2 susceptibility protein BRCA2 Tbio Non-IDG -3.42019 2495.6 219
Histone acetyltransferase p300 EP300 Tchem Epigenetic -3.75838 5701.8 723
Myoblast determination protein 1 MYOD1 Tbio Transcription Factor -3.13423 1281.5 563
Transformation/transcription domain-associated protein TRRAP Tbio Non-IDG -1.58619 36.3 148
Amyloid beta A4 precursor protein-binding family B member 1 APBB1 Tbio Non-IDG -2.30369 219.3 273