Development Level

Tbio 13 | 11,445
Tchem 2 | 1,598

IMPC Phenotype

preweaning lethality, complete... 4 | 979
abnormal coat-hair pigmentatio... 1 | 64
decreased bone mineral density 1 | 126
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
decreased total body fat amoun... 1 | 207
embryonic lethality prior to o... 1 | 239
increased lean body mass 1 | 172
increased startle reflex 1 | 112
prenatal lethality prior to he... 1 | 87
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 11 | 11,493
ovarian cancer 9 | 8,520
Breast cancer 6 | 3,578
Intellectual disability 5 | 1,016
atypical teratoid / rhabdoid tumor 5 | 5,112
osteosarcoma 5 | 7,950
psoriasis 5 | 6,694
Cancer 4 | 2,499
Kidney cancer 4 | 2,613
Lymphoid leukemia 4 | 160
acute myeloid leukemia 4 | 783
diabetes mellitus 4 | 1,728
glioblastoma 4 | 5,792
malignant mesothelioma 4 | 3,232
Immune system cancer 3 | 140
Multiple myeloma 3 | 1,332
gastric cancer 3 | 459
hepatocellular carcinoma 3 | 547
invasive ductal carcinoma 3 | 2,951
lung adenocarcinoma 3 | 2,716
lung cancer 3 | 4,740
medulloblastoma, large-cell 3 | 6,241
non-small cell lung cancer 3 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
primitive neuroectodermal tumor 3 | 3,035
subependymal giant cell astrocytoma 3 | 2,287
Alzheimer's disease 2 | 658
Carcinoma, Hepatocellular 2 | 228
Large intestine cancer 2 | 126
Leukemia, Myelocytic, Acute 2 | 120
Leukemia, Myeloid, Acute 2 | 105
Liver cancer 2 | 604
Liver carcinoma 2 | 240
Multiple Sclerosis 2 | 540
Pick disease 2 | 1,894
Schizophrenia 2 | 1,160
Waldenstrons macroglobulinemia 2 | 765
astrocytic glioma 2 | 2,597
cystic fibrosis 2 | 1,696
dermatomyositis 2 | 966
group 3 medulloblastoma 2 | 4,104
group 4 medulloblastoma 2 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
oligodendroglioma 2 | 2,850
progressive supranuclear palsy 2 | 676
spina bifida 2 | 1,074
Abdominal Pain 1 | 98
Acute blood cancer 1 | 6
Acute leukemia 1 | 15
Amaurosis Fugax 1 | 8
Angina Pectoris 1 | 32
Ankylosing spondylitis 1 | 140
Arterial thrombosis 1 | 9
Arthralgia 1 | 90
Bleeding time prolonged 1 | 31
Breast Neoplasms 1 | 445
Broad-based gait 1 | 19
Chest Pain 1 | 38
DOID:2627 1 | 94
Dizziness 1 | 26
Downward slant of palpebral fissure 1 | 158
Ecchymosis 1 | 66
Epistaxis 1 | 43
Essential thrombocythemia 1 | 10
Fatigue 1 | 182
Flat face 1 | 52
Gingival Hemorrhage 1 | 18
Headache 1 | 37
Hypoplastic myelodysplasia 1 | 18
Hypoplastic toes 1 | 29
Increased megakaryocyte count 1 | 6
Increased tendency to bruise 1 | 66
Kabuki syndrome 1 | 27
MYELODYSPLASTIC SYNDROME 1 | 53
Mammary Neoplasms 1 | 425
Myelofibrosis 1 | 14
Myocardial Infarction 1 | 151
Neoplasm Recurrence, Local 1 | 37
Neutropenia 1 | 72
Paratyphoid fever 1 | 10
Paresthesia 1 | 32
Platelet morphology abnormal 1 | 9
Polycythemia vera 1 | 27
Renal Cell Carcinoma 1 | 214
Somatic mutation 1 | 61
Synophrys 1 | 40
Systemic lupus erythematosus 1 | 194
Thin upper lip vermilion 1 | 67
Thrombocythemia, Essential 1 | 12
Thrombocytopenia 1 | 197
Thrombocytosis 1 | 38
Tinnitus 1 | 19
Transient Cerebral Ischemia 1 | 25
Venous Thrombosis 1 | 47
Vertigo 1 | 29
Weight decreased 1 | 103
Wide nose 1 | 35
X-linked cerebral adrenoleukodystrophy 1 | 116

Tissue

Blood and immune system 15 | 16,909
Cardiovascular System 15 | 15,192
Digestive Tract 15 | 17,369
Endocrine System 15 | 18,159
Female tissues 15 | 17,400
Liver and Pancreas 15 | 16,750
Male tissues 15 | 17,142
Nervous System 15 | 16,725
Respiratory system 15 | 16,393
Skin and soft tissues 15 | 17,230
Urinary Tract 15 | 16,678

Target Family

Non-IDG 6 | 12,091
Enzyme 5 | 4,145
Epigenetic 2 | 242
TF/Epigenetic 1 | 38
Transcription Factor 1 | 1,400

GO Process

histone H3-K4 trimethylation 15 | 15
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Methylcytosine dioxygenase TET3 TET3 Tbio Enzyme -1.96016 82.2 167
Histone-lysine N-methyltransferase 2B KMT2B Tbio Epigenetic -1.93899 84.8 153
Histone H1.2 HIST1H1C Tbio Non-IDG -2.01718 95.3 142
Histone H1.3 HIST1H1D Tbio Non-IDG -1.83212 63.8 66
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit OGT Tchem Enzyme -2.98896 993.7 264
RNA polymerase-associated protein RTF1 homolog RTF1 Tbio Enzyme -1.44682 29.1 157
Zinc finger protein 335 ZNF335 Tbio Transcription Factor -1.17336 14.8 83
WD repeat-containing protein 61 WDR61 Tbio Non-IDG -1.27258 18.3 189
BEN domain-containing protein 3 BEND3 Tbio Non-IDG -1.55740 31.6 81
RNA polymerase-associated protein CTR9 homolog CTR9 Tbio Enzyme -1.24736 19.1 120