Development Level

Tbio 31 | 11,651
Tchem 7 | 1,388
Tdark 4 | 6,593

IMPC Phenotype

preweaning lethality, complete... 5 | 979
decreased body weight 3 | 161
abnormal heart morphology 2 | 162
decreased circulating glucose ... 2 | 126
enlarged heart 2 | 210
increased monocyte cell number 2 | 63
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal cornea morphology 1 | 31
abnormal cranium morphology 1 | 36
abnormal eye morphology 1 | 68
abnormal eye pigmentation 1 | 3
abnormal eye size 1 | 7
abnormal eyelid aperture 1 | 2
abnormal hair texture 1 | 4
abnormal iris morphology 1 | 13
abnormal lens morphology 1 | 81
abnormal maxilla morphology 1 | 17
abnormal tooth morphology 1 | 24
corneal opacity 1 | 32
corneal vascularization 1 | 6
decreased T cell number 1 | 15
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating alkaline... 1 | 46
decreased circulating potassiu... 1 | 20
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased lean body mass 1 | 135
decreased lymphocyte cell numb... 1 | 83
decreased prepulse inhibition 1 | 82
decreased total body fat amoun... 1 | 207
embryonic lethality prior to t... 1 | 278
eyelids fail to open 1 | 3
female infertility 1 | 60
impaired glucose tolerance 1 | 75
increased circulating sodium l... 1 | 71
increased startle reflex 1 | 112
male infertility 1 | 123
mammalian phenotype 1 | 17
tremors 1 | 39

Disease

Carcinoma 28 | 11,493
osteosarcoma 21 | 7,950
ovarian cancer 21 | 8,520
psoriasis 19 | 6,694
lung cancer 14 | 4,740
medulloblastoma, large-cell 14 | 6,241
Cancer 12 | 2,499
group 3 medulloblastoma 12 | 4,104
malignant mesothelioma 11 | 3,232
atypical teratoid / rhabdoid tumor 10 | 5,112
glioblastoma 10 | 5,792
Breast cancer 9 | 3,578
Kidney cancer 9 | 2,613
non-small cell lung cancer 8 | 2,890
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
lung adenocarcinoma 6 | 2,716
oligodendroglioma 6 | 2,850
subependymal giant cell astrocytoma 6 | 2,287
tuberculosis 6 | 2,010
colon cancer 5 | 1,478
ductal carcinoma in situ 5 | 1,745
ependymoma 5 | 4,679
group 4 medulloblastoma 5 | 1,855
invasive ductal carcinoma 5 | 2,951
Acquired scoliosis 4 | 281
Curvature of spine 4 | 282
Intellectual disability 4 | 1,016
Multiple myeloma 4 | 1,332
Pick disease 4 | 1,894
Spinocerebellar ataxia type 7 4 | 13
lung carcinoma 4 | 2,843
pancreatic cancer 4 | 2,398
primitive neuroectodermal tumor 4 | 3,035
Breast Neoplasms 3 | 445
Cognitive delay 3 | 608
Dull intelligence 3 | 645
Global developmental delay 3 | 608
Hypoplastic mandible condyle 3 | 275
Low intelligence 3 | 645
Mandibular hypoplasia 3 | 275
Mental Retardation 3 | 645
Mental and motor retardation 3 | 608
Mental deficiency 3 | 645
Micrognathism 3 | 275
Orbital separation excessive 3 | 244
Poor school performance 3 | 645
Short stature 3 | 531
Small head 3 | 374
adult high grade glioma 3 | 3,801
astrocytic glioma 3 | 2,597
breast carcinoma 3 | 1,638
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
non primary Sjogren syndrome sicca 3 | 891
pediatric high grade glioma 3 | 1,064
primary pancreatic ductal adenocarcinoma 3 | 1,109
sarcoidosis 3 | 370
ulcerative colitis 3 | 1,819
Adenoid Cystic Carcinoma 2 | 99
Arthritis, Juvenile 2 | 126
Arthrogryposis 2 | 54
Atrial Septal Defects 2 | 85
Attention deficit hyperactivity disorder 2 | 278
Autosomal recessive predisposition 2 | 1,442
Bipolar Disorder 2 | 666
Blepharoptosis 2 | 231
Byzanthine arch palate 2 | 194
Carcinoma, Adenoid Cystic 2 | 99
Chronic Lymphocytic Leukemia 2 | 262
Congenital hypoplasia of lung 2 | 48
Disease Models, Animal 2 | 155
Downward slant of palpebral fissure 2 | 158
Flexion contracture of proximal interphalangeal joint 2 | 75
Juvenile arthritis 2 | 126
Leukemia, Lymphocytic, Chronic, B-Cell 2 | 34
Liver cancer 2 | 604
Low set ears 2 | 181
Lymphangioma, Cystic 2 | 21
Muscle hypotonia 2 | 571
Neoplasm Invasiveness 2 | 161
Neoplasm Metastasis 2 | 168
Polyhydramnios 2 | 108
Posteriorly rotated ear 2 | 61
Prostatic Neoplasms 2 | 495
Rheumatoid arthritis 2 | 1,191
Schizophrenia 2 | 1,160
Strabismus 2 | 270
Ventricular Septal Defects 2 | 119
Waldenstrons macroglobulinemia 2 | 765
acute myeloid leukemia 2 | 783
acute quadriplegic myopathy 2 | 1,158
astrocytoma 2 | 1,146
diabetes mellitus 2 | 1,728
interstitial cystitis 2 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
medulloblastoma 2 | 720
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
posterior fossa group B ependymoma 2 | 416
spina bifida 2 | 1,074
tuberculosis and treatment for 6 months 2 | 409
urothelial carcinoma 2 | 318

Tissue

Digestive Tract 41 | 17,369
Endocrine System 41 | 18,159
Female tissues 41 | 17,400
Male tissues 41 | 17,142
Skin and soft tissues 41 | 17,230
Blood and immune system 40 | 16,909
Cardiovascular System 40 | 15,192
Liver and Pancreas 40 | 16,750
Nervous System 40 | 16,725
Respiratory system 40 | 16,393
Urinary Tract 40 | 16,678

Target Family

Non-IDG 17 | 12,091
Epigenetic 14 | 242
Transcription Factor 5 | 1,400
Enzyme 4 | 4,145
Kinase 1 | 634
TF/Epigenetic 1 | 38

GO Process

histone H3 acetylation 42 | 42
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L TAF6L Tdark Enzyme 0.55 0.23 173
Protein Dr1 DR1 Tbio Non-IDG -2.51135 313.8 146
Histone acetyltransferase KAT6B KAT6B Tbio Epigenetic -2.30232 201.0 58
Mitogen-activated protein kinase kinase kinase 7 MAP3K7 Tchem Kinase -1.46817 32.4 765
Inhibitor of growth protein 5 ING5 Tbio Epigenetic -1.34672 20.6 169
Lymphoid enhancer-binding factor 1 LEF1 Tchem Transcription Factor -2.60971 375.2 591
Myoblast determination protein 1 MYOD1 Tbio Transcription Factor -3.16910 1355.7 632
Period circadian protein homolog 1 PER1 Tbio Non-IDG -1.86449 71.4 178
TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L TAF5L Tbio Enzyme -0.10427 1.42 161
Transcriptional adapter 3 TADA3 Tbio Non-IDG -2.53694 342.6 193