Development Level

Tbio 15 | 11,651
Tdark 1 | 6,593

IMPC Phenotype

preweaning lethality, complete... 3 | 979
abnormal behavior 2 | 298
decreased body weight 2 | 161
increased lean body mass 2 | 172
increased mean corpuscular vol... 2 | 92
increased total body fat amoun... 2 | 134
abnormal bone mineralization 1 | 38
abnormal cornea morphology 1 | 31
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
increased circulating creatine... 1 | 5
increased circulating magnesiu... 1 | 10
increased lactate dehydrogenas... 1 | 3

Disease

ovarian cancer 13 | 8,520
Carcinoma 11 | 11,493
osteosarcoma 10 | 7,950
group 3 medulloblastoma 8 | 4,104
Breast cancer 7 | 3,578
ependymoma 7 | 4,679
lung cancer 7 | 4,740
glioblastoma 6 | 5,792
malignant mesothelioma 6 | 3,232
medulloblastoma, large-cell 6 | 6,241
primitive neuroectodermal tumor 6 | 3,035
atypical teratoid / rhabdoid tumor 5 | 5,112
oligodendroglioma 5 | 2,850
Rheumatoid arthritis 4 | 1,191
psoriasis 4 | 6,694
Kidney cancer 3 | 2,613
Multiple myeloma 3 | 1,332
adult high grade glioma 3 | 3,801
astrocytoma 3 | 1,146
colon cancer 3 | 1,478
hepatocellular carcinoma 3 | 547
lung adenocarcinoma 3 | 2,716
non-small cell lung cancer 3 | 2,890
Astrocytoma, Pilocytic 2 | 3,081
Cancer 2 | 2,499
Endometrial cancer 2 | 311
adrenocortical carcinoma 2 | 1,428
aldosterone-producing adenoma 2 | 665
dermatomyositis 2 | 966
gastric cancer 2 | 459
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
medulloblastoma 2 | 720
Adenoid Cystic Carcinoma 1 | 99
Aicardi syndrome 1 | 14
Breast adenoma 1 | 4
Carcinoma, Adenoid Cystic 1 | 99
Cervix uteri carcinoma in situ 1 | 16
Creutzfeldt-Jakob Syndrome 1 | 10
Creutzfeldt-Jakob disease 1 | 21
Distal muscular dystrophy 1 | 8
Endometrial stromal nodule 1 | 11
Endometrial stromal sarcoma 1 | 15
Endometriosis 1 | 540
Focal dermal hypoplasia 1 | 8
Fragile X-associated tremor/ataxia syndrome 1 | 6
Gaucher disease type 1 1 | 180
Immune system cancer 1 | 140
Intellectual disability 1 | 1,016
Intermittent explosive disorder 1 | 4
Leukopenia 1 | 72
Liposarcoma 1 | 20
Liver cancer 1 | 604
Melanoma 1 | 711
Mucositis 1 | 29
Myxoid leiomyosarcoma 1 | 3
Ossifying fibromyxoid tumor 1 | 5
Pick disease 1 | 1,894
Schizophrenia 1 | 1,160
Sclerocornea 1 | 29
Sexual disorder 1 | 3
Skin cancer 1 | 469
Spinocerebellar ataxia type 7 1 | 13
Squamous cell carcinoma of the head and neck 1 | 29
Waldenstrons macroglobulinemia 1 | 765
Xeroderma pigmentosum group B 1 | 20
acute myeloid leukemia 1 | 783
astrocytic glioma 1 | 2,597
diabetes mellitus 1 | 1,728
invasive ductal carcinoma 1 | 2,951
juvenile dermatomyositis 1 | 1,187
lung carcinoma 1 | 2,843
non primary Sjogren syndrome sicca 1 | 891
pancreatic ductal adenocarcinoma liver metastasis 1 | 1,962
pituitary cancer 1 | 1,972
spina bifida 1 | 1,074
subependymal giant cell astrocytoma 1 | 2,287
substance-related disorder 1 | 162
tuberculosis 1 | 2,010

Tissue

Blood and immune system 15 | 16,909
Cardiovascular System 15 | 15,192
Digestive Tract 15 | 17,369
Endocrine System 15 | 18,159
Female tissues 15 | 17,400
Liver and Pancreas 15 | 16,750
Male tissues 15 | 17,142
Nervous System 15 | 16,725
Respiratory system 15 | 16,393
Skin and soft tissues 15 | 17,230
Urinary Tract 15 | 16,678

Target Family

Non-IDG 10 | 12,091
Epigenetic 4 | 242
Enzyme 2 | 4,145

GO Process

histone H2A acetylation 16 | 16
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
E1A-binding protein p400 EP400 Tbio Non-IDG -1.47248 27.6 69
N-alpha-acetyltransferase 40 NAA40 Tbio Enzyme -0.83322 7.67 49
Transformation/transcription domain-associated protein TRRAP Tbio Non-IDG -1.62460 39.0 162
Actin-like protein 6A ACTL6A Tbio Non-IDG -1.45479 28.3 286
Mortality factor 4-like protein 2 MORF4L2 Tbio Non-IDG -0.87952 8.10 128
DNA methyltransferase 1-associated protein 1 DMAP1 Tbio Enzyme -1.20904 16.0 220
Enhancer of polycomb homolog 1 EPC1 Tbio Non-IDG -1.32335 19.2 62
Bromodomain-containing protein 8 BRD8 Tbio Epigenetic -0.69185 6.07 117
Inhibitor of growth protein 3 ING3 Tbio Epigenetic -2.33680 199.4 175
Putative male-specific lethal-3 protein-like 2 MSL3P1 Tdark Non-IDG 0.00000 0