Development Level

Tbio 6 | 11,445
Tchem 1 | 1,598
Tdark 1 | 6,588

Disease

Carcinoma 7 | 11,493
osteosarcoma 4 | 7,950
Intellectual disability 3 | 1,016
lung cancer 3 | 4,740
medulloblastoma, large-cell 3 | 6,241
ovarian cancer 3 | 8,520
Astrocytoma, Pilocytic 2 | 3,081
Liver Cirrhosis, Experimental 2 | 769
adrenocortical carcinoma 2 | 1,428
adult high grade glioma 2 | 3,801
astrocytoma 2 | 1,146
cystic fibrosis 2 | 1,696
ependymoma 2 | 4,679
glioblastoma 2 | 5,792
group 3 medulloblastoma 2 | 4,104
invasive ductal carcinoma 2 | 2,951
non-small cell lung cancer 2 | 2,890
oligodendroglioma 2 | 2,850
pituitary cancer 2 | 1,972
primitive neuroectodermal tumor 2 | 3,035
psoriasis 2 | 6,694
subependymal giant cell astrocytoma 2 | 2,287
tuberculosis 2 | 2,010
Abnormal urinary amino-acid findings 1 | 38
Alcoholic Intoxication, Chronic 1 | 289
Allergic hypersensitivity disease 1 | 126
Amelogenesis imperfecta type 1B 1 | 4
Amelogenesis imperfecta type 1E 1 | 3
Aminoaciduria 1 | 38
Anemia, Megaloblastic 1 | 16
Arthus reaction 1 | 7
Asthma 1 | 385
Asthma, susceptibility to 1 | 11
Ataxia 1 | 15
Atypical lipomatous tumor 1 | 2
Autoimmune hepatitis 1 | 11
Autosomal recessive predisposition 1 | 1,442
Breast cancer 1 | 3,578
Burkitt Lymphoma 1 | 20
Cancer 1 | 2,499
Contact Dermatitis 1 | 81
Cortical blindness 1 | 16
Drug Hypersensitivity 1 | 34
Drug allergy 1 | 36
Duchenne muscular dystrophy 1 | 601
Dull intelligence 1 | 645
Endometriosis 1 | 540
Gaucher disease type 3 1 | 67
Gilles de la Tourette syndrome 1 | 47
Glutamate formiminotransferase deficiency 1 | 1
Growth delay 1 | 114
Growth failure 1 | 114
Growth retardation 1 | 115
Hepatomegaly 1 | 285
Histidinemia 1 | 9
Hypersegmentation of neutrophil nuclei 1 | 1
Kernicterus 1 | 11
Kidney cancer 1 | 2,613
Low intelligence 1 | 645
MENTAL RETARDATION, AUTOSOMAL RECESSIVE 51 1 | 1
Mental Retardation 1 | 645
Mental deficiency 1 | 645
Orotic aciduria 1 | 18
Pelvic inflammatory disease 1 | 21
Pick disease 1 | 1,894
Polycystic ovary syndrome 1 | 360
Poor growth 1 | 114
Poor school performance 1 | 645
Positive ferric chloride test 1 | 1
Propionic acidemia 1 | 16
Rhinitis 1 | 54
Sigmoid colon cancer 1 | 4
Specific language impairment 1 | 34
Tourette Syndrome 1 | 4
Urticaria 1 | 67
Very poor growth 1 | 114
active Crohn's disease 1 | 922
active ulcerative colitis 1 | 764
atypical teratoid/rhabdoid tumor 1 | 357
autosomal dominant Emery-Dreifuss muscular dystrophy 1 | 510
beta-ketothiolase deficiency 1 | 13
cutaneous lupus erythematosus 1 | 1,057
ductal carcinoma in situ 1 | 1,745
facioscapulohumeral dystrophy 1 | 288
gastric cancer 1 | 459
gastric carcinoma 1 | 807
interstitial cystitis 1 | 2,312
interstitial lung disease 1 | 298
intraductal papillary-mucinous adenoma (IPMA) 1 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 1 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 1 | 3,291
juvenile dermatomyositis 1 | 1,187
lung adenocarcinoma 1 | 2,716
lung carcinoma 1 | 2,843
malignant mesothelioma 1 | 3,232
nephrosclerosis 1 | 333
non primary Sjogren syndrome sicca 1 | 891
pancreatic ductal adenocarcinoma liver metastasis 1 | 1,962
pediatric high grade glioma 1 | 1,064
progressive supranuclear palsy 1 | 676

Tissue

Blood and immune system 8 | 16,909
Endocrine System 8 | 18,159
Female tissues 8 | 17,400
Liver and Pancreas 8 | 16,750
Nervous System 8 | 16,725
Cardiovascular System 7 | 15,192
Digestive Tract 7 | 17,369
Male tissues 7 | 17,142
Skin and soft tissues 7 | 17,230
Urinary Tract 7 | 16,678
Respiratory system 6 | 16,393

Target Family

Enzyme 8 | 4,145

GO Process

histidine catabolic process 8 | 8
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Formimidoyltransferase-cyclodeaminase FTCD Tbio Enzyme -2.23276 170.0 418
Carnosine synthase 1 CARNS1 Tbio Enzyme -0.64427 4.21 70
Histamine N-methyltransferase HNMT Tchem Enzyme -2.88300 757.5 234
Histidine decarboxylase HDC Tbio Enzyme -2.65393 472.2 175
Urocanate hydratase UROC1 Tbio Enzyme -1.01946 10.3 60
Probable imidazolonepropionase AMDHD1 Tdark Enzyme -0.17124 1.82 62
Histidine ammonia-lyase HAL Tbio Enzyme -2.01531 102.1 85
Carnosine N-methyltransferase CARNMT1 Tbio Enzyme -0.42597 1.92 80