Development Level

Tbio 20 | 11,178
Tchem 7 | 1,885

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

abnormal bone structure 1 | 187
abnormal craniofacial morpholo... 1 | 33
abnormal embryo size 1 | 220
abnormal embryo turning 1 | 31
abnormal eye anterior chamber ... 1 | 9
abnormal heart left ventricle ... 1 | 16
abnormal skin morphology 1 | 50
abnormal spleen morphology 1 | 55
abnormal tooth morphology 1 | 24
decreased bone mineral content 1 | 151
decreased lean body mass 1 | 135
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
dilated heart left ventricle 1 | 11
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
increased anti-nuclear antigen... 1 | 19
increased bone mineral content 1 | 108
increased heart rate 1 | 23
increased heart weight 1 | 62
increased lean body mass 1 | 172
increased total body fat amoun... 1 | 134
microphthalmia 1 | 26
preweaning lethality, complete... 1 | 979

Disease

ovarian cancer 22 | 8,297
Carcinoma 18 | 11,192
osteosarcoma 18 | 7,766
medulloblastoma, large-cell 14 | 6,086
glioblastoma 13 | 5,635
atypical teratoid / rhabdoid tumor 12 | 4,971
psoriasis 12 | 6,514
invasive ductal carcinoma 11 | 2,867
group 3 medulloblastoma 10 | 4,002
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,902
Breast cancer 9 | 3,469
ependymoma 9 | 4,559
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,872
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,204
pancreatic cancer 9 | 2,322
Cancer 8 | 2,388
lung cancer 8 | 4,607
malignant mesothelioma 8 | 3,135
spina bifida 8 | 1,053
Pick disease 7 | 1,856
breast carcinoma 7 | 1,589
juvenile dermatomyositis 7 | 1,147
lung adenocarcinoma 7 | 2,627
primitive neuroectodermal tumor 7 | 2,957
Amyotrophic lateral sclerosis 6 | 437
interstitial cystitis 6 | 2,237
lung carcinoma 6 | 2,755
pituitary cancer 6 | 1,915
primary pancreatic ductal adenocarcinoma 6 | 1,071
subependymal giant cell astrocytoma 6 | 2,230
Kidney cancer 5 | 2,548
acute quadriplegic myopathy 5 | 1,133
adult high grade glioma 5 | 3,701
astrocytoma 5 | 1,113
colon cancer 5 | 1,428
dermatomyositis 5 | 941
ductal carcinoma in situ 5 | 1,686
group 4 medulloblastoma 5 | 1,806
Astrocytoma, Pilocytic 4 | 3,006
Down syndrome 4 | 480
Rheumatoid arthritis 4 | 1,156
medulloblastoma 4 | 702
oligodendroglioma 4 | 2,768
pediatric high grade glioma 4 | 1,035
Autosomal recessive predisposition 3 | 1,407
Cerebrovascular disease 3 | 223
Multiple myeloma 3 | 1,296
Parkinson's disease 3 | 378
Wilson-Turner syndrome 3 | 14
diabetes mellitus 3 | 1,683
hereditary spastic paraplegia 3 | 313
non-small cell lung cancer 3 | 2,799
ulcerative colitis 3 | 1,765
Alzheimer's disease 2 | 640
Brain Neoplasms 2 | 30
Cholestasis 2 | 154
Congenital Epicanthus 2 | 175
Diabetic retinopathy 2 | 53
Dull intelligence 2 | 634
Epithelioid hemangioendothelioma 2 | 5
Growth delay 2 | 112
Growth failure 2 | 112
Growth retardation 2 | 113
Inflammatory bowel disease 2 | 148
Intellectual disability 2 | 998
Kidney disease 2 | 411
Liver cancer 2 | 589
Low intelligence 2 | 634
Mental Retardation 2 | 634
Mental deficiency 2 | 634
Muscle hypotonia 2 | 562
Neoplasm Metastasis 2 | 160
Orbital separation excessive 2 | 240
Polycystic ovary syndrome 2 | 348
Poor growth 2 | 112
Poor school performance 2 | 634
Schizophrenia 2 | 1,136
Sensorineural Hearing Loss (disorder) 2 | 281
Very poor growth 2 | 112
active Crohn's disease 2 | 882
active ulcerative colitis 2 | 736
astrocytic glioma 2 | 2,530
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 492
cutaneous lupus erythematosus 2 | 1,016
gastric carcinoma 2 | 781
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,911
Agyria 1 | 15
Carcinoma, squamous cell of head and neck 1 | 30
Corneal edema 1 | 14
Diabetes Mellitus, Experimental 1 | 101
Heterotopia, Periventricular, Autosomal Recessive 1 | 2
Hyperglycemia 1 | 134
Intrahepatic cholestasis 1 | 20
Malocclusion 1 | 57
Mitral Valve Prolapse Syndrome 1 | 38
Mitral regurgitation, mild 1 | 31
Sepsis 1 | 22
Short 4th metacarpal 1 | 7
Squamous cell carcinoma of the head and neck 1 | 28
non-syndromic X-linked intellectual disability 1 | 19

Tissue

Blood and immune system 27 | 16,909
Cardiovascular System 27 | 15,192
Digestive Tract 27 | 17,369
Endocrine System 27 | 18,159
Female tissues 27 | 17,400
Liver and Pancreas 27 | 16,750
Male tissues 27 | 17,142
Nervous System 27 | 16,725
Respiratory system 27 | 16,393
Skin and soft tissues 27 | 17,230
Urinary Tract 27 | 16,678

Target Family

Non-IDG 15 | 12,091
Enzyme 4 | 4,145
Kinase 4 | 634
Transcription Factor 4 | 1,400

GO Process

hippo signaling 27 | 27
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Angiomotin AMOT Tchem Non-IDG -1.75932 64.8 318
E3 ubiquitin-protein ligase Praja-2 PJA2 Tbio Enzyme -0.64427 3.70 175
Protocadherin-16 DCHS1 Tbio Non-IDG -1.37602 23.5 62
Serine/threonine-protein kinase 4 STK4 Tchem Kinase -1.53051 32.9 266
Protein KIBRA WWC1 Tbio Non-IDG -1.96854 92.8 130
Tight junction protein ZO-1 TJP1 Tbio Non-IDG -3.20720 1368.9 292
Protocadherin Fat 4 FAT4 Tbio Non-IDG -1.70369 49.6 50
14-3-3 protein epsilon YWHAE Tchem Non-IDG -2.23108 170.5 348
Serine/threonine-protein kinase 3 STK3 Tchem Kinase -1.13339 11.3 303
14-3-3 protein beta/alpha YWHAB Tchem Non-IDG -2.06798 109.1 482