Development Level

Tbio 20 | 10,625
Tchem 7 | 1,890

Collection

Eligible Kinase Proteins 1 | 134

IMPC Term

decreased lean body mass 2 | 195
abnormal bone structure 1 | 131
abnormal embryo size 1 | 112
abnormal embryo turning 1 | 15
abnormal retina morphology 1 | 100
abnormal skin morphology 1 | 23
abnormal spleen morphology 1 | 36
decreased Ly6C low monocyte nu... 1 | 23
decreased body length 1 | 108
decreased bone mineral density 1 | 126
decreased eosinophil cell numb... 1 | 41
decreased gamma-delta T cell n... 1 | 18
decreased grip strength 1 | 123
decreased heart weight 1 | 44
decreased total body fat amoun... 1 | 186
decreased vertical activity 1 | 22
embryonic lethality prior to o... 1 | 148
embryonic lethality prior to t... 1 | 187
increased Ly6C high monocyte n... 1 | 12
increased heart rate 1 | 17
increased lean body mass 1 | 107
increased or absent threshold ... 1 | 128
increased total body fat amoun... 1 | 57
preweaning lethality, complete... 1 | 633
shortened RR interval 1 | 19
shortened ST segment 1 | 9

Disease

ovarian cancer 23 | 8,484
osteosarcoma 19 | 7,933
medulloblastoma, large-cell 14 | 6,234
invasive ductal carcinoma 12 | 2,950
psoriasis 12 | 6,685
atypical teratoid / rhabdoid tumor 11 | 4,369
glioblastoma 11 | 5,572
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,988
Cancer 9 | 2,346
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,956
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,289
Breast cancer 8 | 3,094
lung adenocarcinoma 8 | 2,713
lung cancer 8 | 4,466
pancreatic cancer 8 | 2,300
primitive neuroectodermal tumor 8 | 3,031
spina bifida 8 | 1,064
Pick disease 7 | 1,893
breast carcinoma 7 | 1,614
group 4 medulloblastoma 7 | 1,875
juvenile dermatomyositis 7 | 1,189
lung carcinoma 7 | 2,844
malignant mesothelioma 7 | 3,162
pediatric high grade glioma 7 | 2,712
primary pancreatic ductal adenocarcinoma 7 | 1,271
Amyotrophic Lateral Sclerosis 6 | 431
colon cancer 6 | 1,475
pituitary cancer 6 | 1,972
subependymal giant cell astrocytoma 6 | 2,287
acute quadriplegic myopathy 5 | 1,157
astrocytoma 5 | 1,493
dermatomyositis 5 | 933
ductal carcinoma in situ 5 | 1,745
ependymoma 5 | 2,514
interstitial cystitis 5 | 2,299
sonic hedgehog group medulloblastoma 5 | 1,482
Carcinoma 4 | 2,147
Down syndrome 4 | 548
Rheumatoid Arthritis 4 | 1,160
group 3 medulloblastoma 4 | 2,254
medulloblastoma 4 | 1,524
oligodendroglioma 4 | 2,849
Cerebrovascular disease 3 | 231
Multiple myeloma 3 | 1,327
Parkinson's disease 3 | 364
diabetes mellitus 3 | 1,663
glioblastoma multiforme 3 | 347
hereditary spastic paraplegia 3 | 313
non-small cell lung cancer 3 | 2,798
pilocytic astrocytoma 3 | 3,086
posterior fossa group A ependymoma 3 | 1,511
ulcerative colitis 3 | 2,087
Alzheimer's disease 2 | 644
Cholestasis 2 | 93
Diabetic Retinopathy 2 | 53
Epithelioid hemangioendothelioma 2 | 5
Heterotopia, Periventricular, Autosomal Recessive 2 | 3
Inflammatory bowel disease 2 | 142
Intellectual disability 2 | 573
Kidney disease 2 | 396
Polycystic Ovary Syndrome 2 | 332
Van Maldergem Wetzburger Verloes syndrome 2 | 2
Van Maldergem syndrome 2 | 4
active Crohn's disease 2 | 918
active ulcerative colitis 2 | 477
adult high grade glioma 2 | 2,148
astrocytic glioma 2 | 2,241
atypical teratoid/rhabdoid tumor 2 | 1,095
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 499
cutaneous lupus erythematosus 2 | 1,056
gastric carcinoma 2 | 832
posterior fossa group B ependymoma 2 | 1,530
Adenocarcinoma 1 | 115
Brain disease 1 | 83
Celiac disease 1 | 112
Cerebral artery occlusion 1 | 3
Ciliopathy 1 | 57
Diabetes Mellitus, Experimental 1 | 106
Irritable bowel syndrome 1 | 59
Kidney cancer 1 | 118
Leber congenital amaurosis 1 | 72
Liver disease 1 | 219
Melanoma 1 | 261
Mitral valve insufficiency 1 | 17
Muscular atrophy 1 | 67
Nerve Degeneration 1 | 73
Pancreatitis 1 | 97
Prion disease 1 | 10
Refractive Errors 1 | 18
Renal Cell Carcinoma 1 | 199
Retinal Degeneration 1 | 49
Sideroblastic anemia 1 | 18
Splenic marginal zone lymphoma 1 | 7
Squamous cell carcinoma of esophagus 1 | 82
Wernicke encephalopathy 1 | 12
cone-rod dystrophy 1 | 56
interstitial lung disease 1 | 291
nervous system disorder 1 | 53
non-inflammatory breast cancer 1 | 208
ovarian neoplasm 1 | 97

Tissue

Blood and immune system 27 | 17,995
Cardiovascular System 27 | 17,958
Digestive Tract 27 | 18,473
Endocrine System 27 | 18,512
Female tissues 27 | 18,647
Liver and Pancreas 27 | 18,136
Male tissues 27 | 17,969
Nervous System 27 | 18,561
Respiratory system 27 | 17,484
Skin and soft tissues 27 | 18,115
Urinary Tract 27 | 18,444

Target Family

Non-IDG 15 | 11,971
Enzyme 4 | 4,146
Kinase 4 | 634
Transcription Factor 4 | 1,400

GO Process

hippo signaling 27 | 27
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protein KIBRA WWC1 Tbio Non-IDG -1.88892 84.4 96
Nephrocystin-4 NPHP4 Tbio Non-IDG -1.39275 26.0 48
14-3-3 protein epsilon YWHAE Tchem Non-IDG -2.18406 158.6 309
E3 ubiquitin-protein ligase Praja-2 PJA2 Tbio Enzyme -0.52612 2.59 159
Caspase-3 CASP3 Tchem Enzyme -4.25532 16628.4 1445
Transcriptional enhancer factor TEF-1 TEAD1 Tbio Transcription Factor -1.56556 37.7 135
14-3-3 protein beta/alpha YWHAB Tchem Non-IDG -2.02614 102.4 440
MOB kinase activator 1B MOB1B Tbio Enzyme -0.75722 4.89 195
Serine/threonine-protein kinase LATS1 LATS1 Tbio Kinase -2.20073 158.3 217
Tight junction protein ZO-1 TJP1 Tbio Non-IDG -3.14176 1243.9 230