Development Level

Tbio 22 | 11,445
Tchem 5 | 1,598

Collection

Kinase: IDG Consortium (Target... 1 | 125
RFA-RM-18-021 1 | 328

IMPC Phenotype

abnormal bone structure 1 | 187
abnormal craniofacial morpholo... 1 | 33
abnormal embryo size 1 | 220
abnormal embryo turning 1 | 31
abnormal eye anterior chamber ... 1 | 9
abnormal heart left ventricle ... 1 | 16
abnormal skin morphology 1 | 50
abnormal spleen morphology 1 | 55
abnormal tooth morphology 1 | 24
decreased bone mineral content 1 | 151
decreased lean body mass 1 | 135
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
dilated heart left ventricle 1 | 11
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
increased anti-nuclear antigen... 1 | 19
increased bone mineral content 1 | 108
increased heart rate 1 | 23
increased heart weight 1 | 62
increased lean body mass 1 | 172
increased total body fat amoun... 1 | 134
microphthalmia 1 | 26
preweaning lethality, complete... 1 | 979

Disease

ovarian cancer 23 | 8,520
Carcinoma 19 | 11,493
osteosarcoma 19 | 7,950
medulloblastoma, large-cell 14 | 6,241
atypical teratoid / rhabdoid tumor 13 | 5,112
glioblastoma 13 | 5,792
invasive ductal carcinoma 12 | 2,951
psoriasis 12 | 6,694
group 3 medulloblastoma 11 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,989
Breast cancer 10 | 3,578
ependymoma 10 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
lung cancer 9 | 4,740
pancreatic cancer 9 | 2,398
Cancer 8 | 2,499
lung adenocarcinoma 8 | 2,716
malignant mesothelioma 8 | 3,232
primitive neuroectodermal tumor 8 | 3,035
spina bifida 8 | 1,074
Pick disease 7 | 1,894
breast carcinoma 7 | 1,638
juvenile dermatomyositis 7 | 1,187
lung carcinoma 7 | 2,843
Amyotrophic lateral sclerosis 6 | 451
Kidney cancer 6 | 2,613
colon cancer 6 | 1,478
interstitial cystitis 6 | 2,312
pituitary cancer 6 | 1,972
primary pancreatic ductal adenocarcinoma 6 | 1,109
subependymal giant cell astrocytoma 6 | 2,287
acute quadriplegic myopathy 5 | 1,158
adult high grade glioma 5 | 3,801
astrocytoma 5 | 1,146
dermatomyositis 5 | 966
ductal carcinoma in situ 5 | 1,745
group 4 medulloblastoma 5 | 1,855
Astrocytoma, Pilocytic 4 | 3,081
Down syndrome 4 | 499
Rheumatoid arthritis 4 | 1,191
medulloblastoma 4 | 720
non-small cell lung cancer 4 | 2,890
oligodendroglioma 4 | 2,850
pediatric high grade glioma 4 | 1,064
Autosomal recessive predisposition 3 | 1,442
Cerebrovascular disease 3 | 238
Intellectual disability 3 | 1,016
Liver cancer 3 | 604
Multiple myeloma 3 | 1,332
Parkinson's disease 3 | 392
Wilson-Turner syndrome 3 | 14
diabetes mellitus 3 | 1,728
hereditary spastic paraplegia 3 | 318
ulcerative colitis 3 | 1,819
Alzheimer's disease 2 | 658
Brain Neoplasms 2 | 33
Cerebro-facio-articular syndrome 2 | 2
Cholestasis 2 | 155
Congenital Epicanthus 2 | 177
Diabetic retinopathy 2 | 56
Dull intelligence 2 | 645
Epithelioid hemangioendothelioma 2 | 5
Growth delay 2 | 114
Growth failure 2 | 114
Growth retardation 2 | 115
Hennekam syndrome 2 | 7
Heterotopia, Periventricular, Autosomal Recessive 2 | 3
Inflammatory bowel disease 2 | 151
Kidney disease 2 | 430
Low intelligence 2 | 645
Mental Retardation 2 | 645
Mental deficiency 2 | 645
Muscle hypotonia 2 | 571
Neoplasm Metastasis 2 | 168
Orbital separation excessive 2 | 244
Polycystic ovary syndrome 2 | 360
Poor growth 2 | 114
Poor school performance 2 | 645
Schizophrenia 2 | 1,160
Sensorineural Hearing Loss (disorder) 2 | 284
Van Maldergem Wetzburger Verloes syndrome 2 | 2
Van Maldergem syndrome 2 | 5
Very poor growth 2 | 114
active Crohn's disease 2 | 922
active ulcerative colitis 2 | 764
astrocytic glioma 2 | 2,597
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
cutaneous lupus erythematosus 2 | 1,057
gastric carcinoma 2 | 807
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
Angle class 3 malocclusion 1 | 57
Carcinoma, squamous cell of head and neck 1 | 31
Hyperglycemia 1 | 137
Intrahepatic cholestasis 1 | 20
Malocclusion 1 | 57
Mitral Valve Prolapse Syndrome 1 | 39
Mitral regurgitation, mild 1 | 32
Sepsis 1 | 24
Short 4th metacarpal 1 | 7

Tissue

Blood and immune system 27 | 16,909
Cardiovascular System 27 | 15,192
Digestive Tract 27 | 17,369
Endocrine System 27 | 18,159
Female tissues 27 | 17,400
Liver and Pancreas 27 | 16,750
Male tissues 27 | 17,142
Nervous System 27 | 16,725
Respiratory system 27 | 16,393
Skin and soft tissues 27 | 17,230
Urinary Tract 27 | 16,678

Target Family

Non-IDG 15 | 12,091
Enzyme 4 | 4,145
Kinase 4 | 634
Transcription Factor 4 | 1,400

GO Process

hippo signaling 27 | 27
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
E3 ubiquitin-protein ligase Praja-2 PJA2 Tbio Enzyme -0.64427 3.70 175
Protein KIBRA WWC1 Tbio Non-IDG -1.96854 92.8 130
Angiomotin AMOT Tbio Non-IDG -1.75932 64.8 318
Tight junction protein ZO-1 TJP1 Tbio Non-IDG -3.20720 1368.9 292
Protocadherin Fat 4 FAT4 Tbio Non-IDG -1.70369 49.6 50
Protocadherin-16 DCHS1 Tbio Non-IDG -1.37602 23.5 62
Serine/threonine-protein kinase 4 STK4 Tchem Kinase -1.53051 32.9 266
14-3-3 protein beta/alpha YWHAB Tchem Non-IDG -2.06798 109.1 482
Caspase-3 CASP3 Tchem Enzyme -4.32112 18132.3 1689
Transcriptional enhancer factor TEF-1 TEAD1 Tbio Transcription Factor -1.71108 45.2 164