Development Level

Tbio 7 | 11,651
Tchem 1 | 1,388

IMPC Phenotype

increased body weight 1 | 25
preweaning lethality, complete... 1 | 979

Disease

Carcinoma 8 | 11,493
psoriasis 6 | 6,694
osteosarcoma 5 | 7,950
Craniofacial Abnormalities 4 | 151
Kidney cancer 4 | 2,613
medulloblastoma, large-cell 4 | 6,241
ovarian cancer 4 | 8,520
Breast cancer 3 | 3,578
Cancer 3 | 2,499
atypical teratoid / rhabdoid tumor 3 | 5,112
interstitial cystitis 3 | 2,312
lung cancer 3 | 4,740
Acquired metabolic disease 2 | 336
Acquired scoliosis 2 | 281
Adenoma 2 | 167
Arthritis, Rheumatoid 2 | 174
Bilateral fifth finger clinodactyly 2 | 110
Brachydactyly 2 | 156
Curvature of little finger 2 | 110
Curvature of spine 2 | 282
Downward slant of palpebral fissure 2 | 158
Flatfoot 2 | 73
Fused vertebrae 2 | 25
Gastrointestinal Stromal Tumors 2 | 48
Late tooth eruption 2 | 61
Liver cancer 2 | 604
Low set ears 2 | 181
Orbital separation excessive 2 | 244
Polydactyly 2 | 107
Rheumatoid arthritis 2 | 1,191
Short middle phalanx of the 5th finger 2 | 13
Spinal fusion 2 | 25
Strabismus 2 | 270
Syndactyly 2 | 88
Vertebral body fusion 2 | 25
adult high grade glioma 2 | 3,801
glioblastoma 2 | 5,792
group 3 medulloblastoma 2 | 4,104
malignant mesothelioma 2 | 3,232
posterior fossa group A ependymoma 2 | 468
primitive neuroectodermal tumor 2 | 3,035
Abnormality of the ankles 1 | 5
Abnormality of the radius 1 | 3
Abnormality of the tibia 1 | 9
Absent toes 1 | 4
Absent/hypoplastic middle phalanx of 5th finger 1 | 4
Aplasia/Hypoplasia involving the metacarpal bones 1 | 5
Aplasia/Hypoplasia of metatarsal bones 1 | 3
BRACHYDACTYLY, TYPE A1 (disorder) 1 | 3
BRACHYDACTYLY, TYPE A2 1 | 4
Brachydactyly syndrome type C 1 | 2
Brachydactyly type A2 1 | 3
Brachydactyly type C 1 | 2
Brachydactyly, Type C 1 | 2
Bracket epiphysis of the middle phalanx of the 2nd finger 1 | 3
Bracket epiphysis of the middle phalanx of the 5th finger 1 | 3
CHROMOSOME 10q22.3-q23.2 DELETION SYNDROME 1 | 2
Char syndrome 1 | 1
Chondrodysplasia, Grebe Type 1 | 3
Chromosome 18q deletion syndrome 1 | 10
Congenital Hand Deformities 1 | 8
Congenital hypoplasia of femur 1 | 8
Cronkhite-Canada syndrome 1 | 1
Disproportionately short middle phalanges 1 | 6
Distal femoral bowing 1 | 3
Ductus Arteriosus, Patent 1 | 6
Fibular aplasia 1 | 6
Fibular hypoplasia and complex brachydactyly 1 | 4
Fifth finger distal interphalangeal joint symphalangism 1 | 1
Fusion of the terminal and middle phalanges of the 5th finger 1 | 1
Hand Deformities, Congenital 1 | 8
Hyperplastic colonic polyposis 1 | 1
Hypoplastic/aplastic fibulae 1 | 5
Hypoplastic/aplastic middle phalanx (2nd finger) 1 | 4
Juvenile colonic polyposis 1 | 1
Madelung Deformity 1 | 5
Medially deviated second toe 1 | 3
Mesoaxial hand polydactyly 1 | 4
Multiple synostoses syndrome 2 1 | 2
Osteoarthritis of hip 1 | 6
POLYPOSIS SYNDROME, HEREDITARY MIXED, 1 1 | 3
Polyposis Syndrome, Hereditary Mixed, 2 1 | 1
Proximal symphalangism 1 | 7
Radial bowing 1 | 13
Second finger clinodactyly 1 | 5
Short digit 1 | 2
Short first metacarpals 1 | 11
Short hallux 1 | 16
Short index finger 1 | 6
Short middle phalanges 1 | 12
Shortening of all proximal phalanges of the fingers 1 | 2
Spondylolysis 1 | 14
Symphalangism, proximal, 1b 1 | 2
Synostosis of carpal bones 1 | 9
Thoracic outlet syndrome 1 | 7
Thumb deformity 1 | 3
Triangular shaped middle phalanx of the 2nd finger 1 | 3
Triangular shaped middle phalanx of the 5th finger 1 | 3
Ulnar angulation of the index finger 1 | 5
Very short digits 1 | 2

Tissue

Endocrine System 8 | 18,159
Male tissues 8 | 17,142
Urinary Tract 8 | 16,678
Digestive Tract 7 | 17,369
Female tissues 7 | 17,400
Skin and soft tissues 7 | 17,230
Blood and immune system 6 | 16,909
Liver and Pancreas 6 | 16,750
Nervous System 6 | 16,725
Respiratory system 6 | 16,393
Cardiovascular System 4 | 15,192

Target Family

Transcription Factor 4 | 1,400
Non-IDG 3 | 12,091
Kinase 1 | 634

GO Process

hindlimb morphogenesis 8 | 8
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protein patched homolog 1 PTCH1 Tbio Non-IDG -3.04637 1057.4 452
Homeobox protein Hox-D10 HOXD10 Tbio Transcription Factor -1.78620 51.3 214
Transcription factor AP-2-beta TFAP2B Tbio Transcription Factor -1.74089 52.9 225
Bone morphogenetic protein receptor type-1A BMPR1A Tchem Kinase -2.34984 211.0 622
Sal-like protein 3 SALL3 Tbio Transcription Factor -0.98197 10.1 22
Homeobox protein Hox-D9 HOXD9 Tbio Transcription Factor -1.52954 36.2 137
Formin-1 FMN1 Tbio Non-IDG -2.80166 584.6 58
Growth/differentiation factor 5 GDF5 Tbio Non-IDG -2.57648 401.8 301