Development Level

Tchem 3 | 1,598
Tbio 2 | 11,445

IMPC Phenotype

abnormal seminal vesicle morph... 1 | 114
decreased lymphocyte cell numb... 1 | 83
hydrometra 1 | 53
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
small superior vagus ganglion 1 | 74

Disease

Autosomal recessive congenital ichthyosis 3 | 11
Carcinoma 3 | 11,493
Congenital ichthyosiform erythroderma 3 | 28
Actinic keratosis 2 | 21
Anhidrosis 2 | 23
Cancer 2 | 2,499
Congenital Nonbullous Ichthyosiform Erythroderma 2 | 16
Congenital ichthyosis 2 | 3
Congenital non-bullous ichthyosiform erythroderma 2 | 7
ICHTHYOSIFORM ERYTHRODERMA, CONGENITAL, NONBULLOUS, 1 2 | 3
Ichthyosiform erythroderma, Brocq congenital, nonbullous form 2 | 2
Ichthyosis 2 | 56
Ichthyosis, Congenital, Autosomal Recessive 2 2 | 3
Ichthyosis, Lamellar 2 | 4
Self-Healing Collodion Baby 2 | 3
esophageal adenocarcinoma 2 | 737
osteosarcoma 2 | 7,950
ovarian cancer 2 | 8,520
psoriasis 2 | 6,694
Abnormal helices 1 | 11
Absence of eyebrows 1 | 31
Alopecia 1 | 115
Aplasia/Hypoplasia of the eyebrow 1 | 31
Arthritis, Juvenile 1 | 126
Asthma 1 | 385
Atherosclerosis 1 | 291
Autosomal recessive predisposition 1 | 1,442
Bipolar Disorder 1 | 666
Breast cancer 1 | 3,578
Congenital deafness 1 | 185
Corneal erosion 1 | 16
Deafness 1 | 198
Decreased joint mobility 1 | 53
Dermatologic disorders 1 | 93
Dry skin 1 | 75
Dull intelligence 1 | 645
Ectropion 1 | 38
Esophageal Neoplasms 1 | 69
Everted lower lip vermilion 1 | 54
Exfoliative dermatitis 1 | 24
Failure to gain weight 1 | 365
Growth delay 1 | 114
Growth failure 1 | 114
Growth retardation 1 | 115
Hair shaft abnormalities 1 | 30
Hearing Loss, Partial 1 | 185
Hyperalgesia 1 | 83
Hyperkeratosis 1 | 50
Hypertension 1 | 396
Hypertensive disease 1 | 292
Hypohidrosis 1 | 34
Hypotrichosis 1 | 47
ICHTHYOSIS, CONGENITAL, AUTOSOMAL RECESSIVE 3 1 | 1
Ichthyoses 1 | 41
Ichthyosiform Erythroderma, Congenital 1 | 6
Ichthyosis, Lamellar, 5 1 | 1
Intellectual disability 1 | 1,016
Juvenile arthritis 1 | 126
Keratitis 1 | 62
Lack of skin elasticity 1 | 10
Low intelligence 1 | 645
Mental Retardation 1 | 645
Mental deficiency 1 | 645
Nail Diseases 1 | 24
Nail abnormality 1 | 22
Palmoplantar keratosis 1 | 74
Paralysed 1 | 42
Pediatric failure to thrive 1 | 365
Peripheral Nervous System Diseases 1 | 52
Peripheral Neuropathy 1 | 134
Poor growth 1 | 114
Poor school performance 1 | 645
Prostatic Neoplasms 1 | 495
Protruding lower lip 1 | 54
Pruritus 1 | 58
Schizophrenia 1 | 1,160
Skin Diseases 1 | 71
Small genitalia 1 | 13
Sparse hair 1 | 59
Sparse or absent eyebrows 1 | 31
Sparse/absent eyebrows 1 | 31
Stretched skin 1 | 10
Thin, sparse hair 1 | 59
Tinea corporis 1 | 25
Very poor growth 1 | 114
Xerosis 1 | 75
cutaneous lupus erythematosus 1 | 1,057
cystic fibrosis 1 | 1,696
facioscapulohumeral dystrophy 1 | 288
glioblastoma 1 | 5,792
hair abnormalities (non-specific) 1 | 30
hearing impairment 1 | 199
lung adenocarcinoma 1 | 2,716
lung cancer 1 | 4,740
lung carcinoma 1 | 2,843
non-small cell lung cancer 1 | 2,890
pancreatic cancer 1 | 2,398
pancreatic carcinoma 1 | 562
sarcoidosis 1 | 370
uncontrolled asthma 1 | 56

Tissue

Blood and immune system 5 | 16,909
Digestive Tract 5 | 17,369
Endocrine System 5 | 18,159
Female tissues 5 | 17,400
Male tissues 5 | 17,142
Nervous System 5 | 16,725
Skin and soft tissues 5 | 17,230
Liver and Pancreas 4 | 16,750
Urinary Tract 4 | 16,678
Respiratory system 3 | 16,393
Cardiovascular System 2 | 15,192

Target Family

Enzyme 5 | 4,145

GO Process

hepoxilin biosynthetic process 5 | 5
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Arachidonate 12-lipoxygenase, 12R-type ALOX12B Tbio Enzyme -1.33994 24.1 71
Arachidonate 12-lipoxygenase, 12S-type ALOX12 Tchem Enzyme -2.35458 223.8 137
Hydroperoxide isomerase ALOXE3 ALOXE3 Tbio Enzyme -1.51120 32.2 118
Arachidonate 15-lipoxygenase B ALOX15B Tchem Enzyme -1.72305 55.2 171
Arachidonate 15-lipoxygenase ALOX15 Tchem Enzyme -2.43772 277.6 185