Development Level

Tbio 38 | 10,625
Tdark 12 | 7,003
Tchem 7 | 1,890
Tclin 1 | 602

Collection

Eligible Ion Channel Proteins 1 | 117

IMPC Term

preweaning lethality, complete... 5 | 633
increased startle reflex 3 | 38
decreased body length 2 | 108
increased grip strength 2 | 83
abnormal bone mineralization 1 | 55
abnormal bone structure 1 | 131
abnormal coat/ hair morphology 1 | 18
abnormal embryo size 1 | 112
abnormal iris morphology 1 | 12
abnormal lens morphology 1 | 73
abnormal limb bud morphology 1 | 15
abnormal limb morphology 1 | 7
abnormal neural tube closure 1 | 37
abnormal placenta size 1 | 10
abnormal retinal blood vessel ... 1 | 18
abnormal skin coloration 1 | 18
abnormal spleen morphology 1 | 36
abnormal tail morphology 1 | 17
aorta dilation 1 | 3
cyanosis 1 | 6
decreased KLRG1+ CD8 alpha bet... 1 | 8
decreased basophil cell number 1 | 11
decreased body weight 1 | 174
decreased bone mineral content 1 | 157
decreased bone mineral density 1 | 126
decreased circulating chloride... 1 | 32
decreased circulating triglyce... 1 | 83
decreased mean platelet volume 1 | 12
edema 1 | 11
embryonic lethality prior to o... 1 | 148
embryonic lethality prior to t... 1 | 187
enlarged heart 1 | 111
head bobbing 1 | 3
hemorrhage 1 | 12
hydrops fetalis 1 | 22
improved glucose tolerance 1 | 56
increased circulating HDL chol... 1 | 63
increased circulating calcium ... 1 | 32
increased circulating sodium l... 1 | 71
increased exploration in new e... 1 | 56
increased mean corpuscular vol... 1 | 91
oligodactyly 1 | 14
pale yolk sac 1 | 12
pallor 1 | 13
respiratory system phenotype 1 | 2
thrombocytosis 1 | 23

Disease

ovarian cancer 33 | 8,484
osteosarcoma 31 | 7,933
glioblastoma 24 | 5,572
psoriasis 24 | 6,685
pilocytic astrocytoma 23 | 3,086
atypical teratoid / rhabdoid tumor 21 | 4,369
medulloblastoma, large-cell 21 | 6,234
intraductal papillary-mucinous neoplasm (IPMN) 18 | 3,289
lung cancer 16 | 4,466
primitive neuroectodermal tumor 15 | 3,031
ulcerative colitis 15 | 2,087
Cancer 14 | 2,346
Carcinoma 14 | 2,147
pediatric high grade glioma 14 | 2,712
invasive ductal carcinoma 13 | 2,950
pituitary cancer 13 | 1,972
subependymal giant cell astrocytoma 13 | 2,287
intraductal papillary-mucinous carcinoma (IPMC) 12 | 2,988
lung carcinoma 12 | 2,844
malignant mesothelioma 12 | 3,162
interstitial cystitis 11 | 2,299
intraductal papillary-mucinous adenoma (IPMA) 11 | 2,956
Breast cancer 10 | 3,094
breast carcinoma 10 | 1,614
lung adenocarcinoma 10 | 2,713
non-small cell lung cancer 10 | 2,798
colon cancer 9 | 1,475
cystic fibrosis 9 | 1,665
ependymoma 9 | 2,514
juvenile dermatomyositis 9 | 1,189
oligodendroglioma 9 | 2,849
astrocytic glioma 8 | 2,241
astrocytoma 8 | 1,493
ductal carcinoma in situ 8 | 1,745
posterior fossa group A ependymoma 8 | 1,511
primary Sjogren syndrome 8 | 789
Pick disease 7 | 1,893
Rheumatoid Arthritis 7 | 1,160
adult high grade glioma 7 | 2,148
group 3 medulloblastoma 7 | 2,254
nasopharyngeal carcinoma 7 | 1,056
pancreatic cancer 7 | 2,300
tuberculosis 7 | 1,557
cutaneous lupus erythematosus 6 | 1,056
dermatomyositis 6 | 933
sonic hedgehog group medulloblastoma 6 | 1,482
Atopic dermatitis 5 | 944
IGA Glomerulonephritis 5 | 454
Mammary Neoplasms 5 | 410
Multiple Sclerosis 5 | 498
Multiple myeloma 5 | 1,327
Waldenstrons macroglobulinemia 5 | 765
acute quadriplegic myopathy 5 | 1,157
adrenocortical carcinoma 5 | 1,427
chronic rhinosinusitis 5 | 512
group 4 medulloblastoma 5 | 1,875
medulloblastoma 5 | 1,524
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,795
posterior fossa group B ependymoma 5 | 1,530
primary pancreatic ductal adenocarcinoma 5 | 1,271
Polycystic Ovary Syndrome 4 | 332
acute myeloid leukemia 4 | 780
diabetes mellitus 4 | 1,663
progressive supranuclear palsy 4 | 674
tuberculosis and treatment for 6 months 4 | 686
Alzheimer's disease 3 | 644
Cerebrovascular disease 3 | 231
Colorectal Neoplasms 3 | 217
Diaphragmatic Hernia 3 | 40
Down syndrome 3 | 548
Duchenne muscular dystrophy 3 | 602
Endometriosis 3 | 535
Epilepsy 3 | 346
Heart disease 3 | 279
Liver carcinoma 3 | 217
Neurodegenerative disease 3 | 383
Obesity 3 | 616
Osteoporosis 3 | 257
aldosterone-producing adenoma 3 | 664
cystic fibrosis and chronic rhinosinusitis 3 | 213
nephrosclerosis 3 | 329
non-small cell lung carcinoma 3 | 413
sarcoidosis 3 | 358
Arthritis 2 | 248
Hypersensitivity reaction type II disease 2 | 235
Hypertension 2 | 287
Hypertensive disease 2 | 193
Inflammatory bowel disease 2 | 142
Kidney disease 2 | 396
Leukemia 2 | 88
Lung disease 2 | 132
Peripheral vascular disease 2 | 90
Prostatic Neoplasms 2 | 471
Spontaneous abortion 2 | 108
active Crohn's disease 2 | 918
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 499
esophageal adenocarcinoma 2 | 737
gastric carcinoma 2 | 832
head and neck cancer 2 | 270
spina bifida 2 | 1,064

Tissue

Blood and immune system 58 | 17,995
Cardiovascular System 58 | 17,958
Digestive Tract 57 | 18,473
Endocrine System 57 | 18,512
Female tissues 57 | 18,647
Liver and Pancreas 57 | 18,136
Male tissues 57 | 17,969
Nervous System 57 | 18,561
Respiratory system 57 | 17,484
Skin and soft tissues 57 | 18,115
Urinary Tract 57 | 18,444

Target Family

Non-IDG 32 | 11,971
Enzyme 15 | 4,146
Transcription Factor 7 | 1,400
Transporter 2 | 473
Epigenetic 1 | 242
Ion Channel 1 | 341

GO Process

hematopoietic progenitor cell ... 58 | 58
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Homeobox protein Hox-B3 HOXB3 Tbio Transcription Factor -1.60816 41.2 104
Blood vessel epicardial substance BVES Tbio Non-IDG -1.46376 36.1 156
DNA topoisomerase 2-alpha TOP2A Tclin Enzyme -2.81595 662.3 551
Bone morphogenetic protein 4 BMP4 Tchem Non-IDG -3.16723 1539.5 438
Elongation factor 2 EEF2 Tchem Non-IDG -2.93803 911.5 347
Transmembrane protein 190 TMEM190 Tdark Non-IDG 0.20 0.91 12
Probable E3 ubiquitin-protein ligase HERC6 HERC6 Tdark Enzyme -0.53762 4.15 30
Zinc finger protein 784 ZNF784 Tdark Transcription Factor 0.00000 13
N-acetyltransferase ESCO2 ESCO2 Tbio Enzyme -2.35311 229.2 53
Zinc finger and BTB domain-containing protein 24 ZBTB24 Tbio Transcription Factor -0.81068 8.70 94