Development Level

Tbio 37 | 11,651
Tdark 12 | 6,593
Tchem 6 | 1,388
Tclin 2 | 612

Collection

Ion Channel: IDG Consortium (T... 1 | 99
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 7 | 979
abnormal behavior 2 | 298
decreased body length 2 | 101
abnormal bone structure 1 | 187
abnormal coat- hair morphology 1 | 19
abnormal embryo size 1 | 220
abnormal heart morphology 1 | 162
abnormal iris morphology 1 | 13
abnormal limb morphology 1 | 13
abnormal liver morphology 1 | 17
abnormal neural tube closure 1 | 46
abnormal placenta size 1 | 20
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal seminal vesicle morph... 1 | 114
abnormal skin morphology 1 | 50
abnormal sleep behavior 1 | 70
abnormal spleen morphology 1 | 55
abnormal tail morphology 1 | 25
abnormal testis morphology 1 | 43
aorta stenosis 1 | 2
cyanosis 1 | 7
decreased basophil cell number 1 | 16
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased heart left ventricle... 1 | 28
decreased heart rate 1 | 18
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
decreased mean platelet volume 1 | 25
decreased threshold for audito... 1 | 26
decreased vertical activity 1 | 208
edema 1 | 59
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
enlarged testis 1 | 6
head bobbing 1 | 5
hemorrhage 1 | 23
hyperactivity 1 | 148
increased body length 1 | 32
increased circulating calcium ... 1 | 34
increased circulating glucose ... 1 | 24
increased circulating sodium l... 1 | 71
increased grip strength 1 | 41
increased mean corpuscular vol... 1 | 92
increased startle reflex 1 | 112
pale yolk sac 1 | 25
pallor 1 | 34
preweaning lethality, incomple... 1 | 499
respiratory system phenotype 1 | 2
short tibia 1 | 97
thin ventricular wall 1 | 24
thrombocytosis 1 | 27

Disease

Carcinoma 44 | 11,493
ovarian cancer 34 | 8,520
osteosarcoma 31 | 7,950
glioblastoma 25 | 5,792
psoriasis 24 | 6,694
Astrocytoma, Pilocytic 23 | 3,081
atypical teratoid / rhabdoid tumor 21 | 5,112
medulloblastoma, large-cell 21 | 6,241
Kidney cancer 19 | 2,613
intraductal papillary-mucinous neoplasm (IPMN) 19 | 3,291
adult high grade glioma 18 | 3,801
lung cancer 18 | 4,740
ependymoma 17 | 4,679
group 3 medulloblastoma 16 | 4,104
Cancer 15 | 2,499
primitive neuroectodermal tumor 15 | 3,035
ulcerative colitis 15 | 1,819
invasive ductal carcinoma 14 | 2,951
intraductal papillary-mucinous carcinoma (IPMC) 13 | 2,989
lung carcinoma 13 | 2,843
malignant mesothelioma 13 | 3,232
pituitary cancer 13 | 1,972
subependymal giant cell astrocytoma 13 | 2,287
Breast cancer 12 | 3,578
non-small cell lung cancer 12 | 2,890
astrocytic glioma 11 | 2,597
breast carcinoma 11 | 1,638
cystic fibrosis 11 | 1,696
intraductal papillary-mucinous adenoma (IPMA) 11 | 2,955
colon cancer 10 | 1,478
interstitial cystitis 10 | 2,312
lung adenocarcinoma 10 | 2,716
oligodendroglioma 10 | 2,850
ductal carcinoma in situ 9 | 1,745
juvenile dermatomyositis 9 | 1,187
pancreatic cancer 8 | 2,398
primary Sjogren syndrome 8 | 735
tuberculosis 8 | 2,010
Pick disease 7 | 1,894
nasopharyngeal carcinoma 7 | 1,058
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
Atopic dermatitis 6 | 952
Breast Neoplasms 6 | 445
Cognitive delay 6 | 608
Global developmental delay 6 | 608
Liver Cirrhosis, Experimental 6 | 769
Mental and motor retardation 6 | 608
Rheumatoid arthritis 6 | 1,191
adrenocortical carcinoma 6 | 1,428
astrocytoma 6 | 1,146
cutaneous lupus erythematosus 6 | 1,057
dermatomyositis 6 | 966
Autosomal recessive predisposition 5 | 1,442
Intellectual disability 5 | 1,016
Mammary Neoplasms 5 | 425
Multiple myeloma 5 | 1,332
Schizophrenia 5 | 1,160
Seizures 5 | 596
Waldenstrons macroglobulinemia 5 | 765
acute quadriplegic myopathy 5 | 1,158
chronic rhinosinusitis 5 | 512
medulloblastoma 5 | 720
Cerebrovascular disease 4 | 238
Congenital Epicanthus 4 | 177
Duchenne muscular dystrophy 4 | 601
Epilepsy 4 | 792
Immunologic Deficiency Syndromes 4 | 113
Muscle hypotonia 4 | 571
Neurodegenerative disease 4 | 414
Polycystic ovary syndrome 4 | 360
Splenomegaly 4 | 190
acute myeloid leukemia 4 | 783
diabetes mellitus 4 | 1,728
primary pancreatic ductal adenocarcinoma 4 | 1,109
progressive supranuclear palsy 4 | 676
Arthritis, Rheumatoid 3 | 174
Brachycephaly 3 | 88
Broad cranium shape 3 | 88
Carcinoma, Hepatocellular 3 | 228
Depressive disorder 3 | 409
Diarrhea 3 | 253
Disease Models, Animal 3 | 155
Dull intelligence 3 | 645
Heart disease 3 | 306
Hepatomegaly 3 | 285
Isolated cases 3 | 72
Liver cancer 3 | 604
Liver carcinoma 3 | 240
Melanoma 3 | 711
Multiple Sclerosis 3 | 540
Pneumonia 3 | 174
Poor school performance 3 | 645
Skin cancer 3 | 469
Wide skull shape 3 | 88
aldosterone-producing adenoma 3 | 665
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
cystic fibrosis and chronic rhinosinusitis 3 | 214
nephrosclerosis 3 | 333
posterior fossa group A ependymoma 3 | 468
spina bifida 3 | 1,074

Tissue

Blood and immune system 57 | 16,909
Endocrine System 57 | 18,159
Male tissues 57 | 17,142
Digestive Tract 56 | 17,369
Female tissues 56 | 17,400
Skin and soft tissues 56 | 17,230
Respiratory system 55 | 16,393
Liver and Pancreas 54 | 16,750
Urinary Tract 54 | 16,678
Cardiovascular System 53 | 15,192
Nervous System 53 | 16,725

Target Family

Non-IDG 31 | 12,091
Enzyme 14 | 4,145
Transcription Factor 7 | 1,400
Transporter 2 | 473
Epigenetic 1 | 242
Ion Channel 1 | 344
Kinase 1 | 634

GO Process

hematopoietic progenitor cell ... 57 | 57
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Stonin-2 STON2 Tbio Non-IDG -1.43585 30.0 11
Sphingomyelin phosphodiesterase 3 SMPD3 Tbio Enzyme -1.84613 78.5 126
Pygopus homolog 1 PYGO1 Tdark Epigenetic -0.48368 2.66 135
Paired amphipathic helix protein Sin3a SIN3A Tbio Non-IDG -1.93639 70.1 171
Transforming growth factor beta-1 TGFB1 Tchem Non-IDG -3.84680 5672.0 1222
Single-stranded DNA-binding protein 3 SSBP3 Tbio Non-IDG -1.53585 34.1 98
Zinc finger and BTB domain-containing protein 24 ZBTB24 Tbio Transcription Factor -0.95306 9.98 105
Hyaluronidase-2 HYAL2 Tbio Enzyme -2.01424 105.1 212
Zinc finger protein 784 ZNF784 Tdark Transcription Factor 0.00000 19
Probable E3 ubiquitin-protein ligase HERC6 HERC6 Tdark Enzyme -0.66272 4.25 39